Late Antiquity saw a shift from polytheism to monotheism with the rise of religions like Mithraism and early Christianity between the 3rd and 4th centuries AD. During this time, Christians faced periods of persecution, most notably under Emperor Diocletian, until Emperor Constantine granted tolerance to Christianity in 313. Archaeological sites like Dura Europos provide evidence of this transition, with remains showing spaces for worship of traditional gods, Mithraism, and early Christian churches and synagogues decorated with biblical scenes.