This document summarizes the physiology of the human menstrual cycle and ovulation. It describes the complex interactions between the hypothalamus, pituitary gland, ovaries, and endometrium that regulate the cycle. Key events include follicular development in the ovaries driven by FSH and LH from the pituitary. This results in ovulation of an egg. The ruptured follicle then forms the corpus luteum, which produces progesterone. Progesterone prepares the endometrium for potential implantation. If implantation does not occur, the corpus luteum regresses and menstruation begins, starting a new cycle.