On World Autism Day, April 2, 2015, Swinburne University of Technology commenced offering a seven-week Massive Open Online Course (MOOC) for families, educators and carers who support individuals on the Autism spectrum. Blackboard OpenEducation MOOC platform hosted the Autism MOOC enabling over 15,000 enrolments and use of groups within the MOOC environment. This presentation demonstrates how the MOOC was designed and delivered via Blackboard OpenEducation, and how the MOOC activities were designed based on the e-tivity model (Salmon, 2013) to faciliate interaction. The presenters will provide an overview of the similiarities and differences in the design of the Autism MOOC, and the Carpe Diem MOOC which was offered by the Learning Transformations Unit at Swinburne University in 2014. Reflections on the design processes for these MOOCs will highlight the issues and challenges when designing an interactive MOOC for large cohorts. Delivered at Innovate and Educate: Teaching and Learning Conference by Blackboard. 24 -27 August 2015 in Adelaide, Australia.