On 17 and 18 June 2020 the EPA held its National Water Event as an online conference.
This presentation was by Con McLaughlin, Donegal County Council and Andy Griggs, Armagh City, Banbridge and Craigavon District Council.
This year's theme was 'Restoring our waters'.
This years event was free to attend. It was the EPA's largest water event ever, with over 1250 attending.
To everyone who joined us: thanks for attending; thanks for your probing questions; thanks for your passion; thanks for caring about our waters. We can achieve more working together.
Special thanks to all our presenters and the team who worked behind the scenes to make sure this years conference happened.
For science and stories about water quality in Ireland, check out www.catchments.ie
This presentation was given on 17 July 2020 as part of the EPA's online Water Conference by Feargal Ó'Coigligh, Department of Housing Planning and Local Government.
On 17 and 18 June 2020 the EPA held its National Water Event as an online conference.
This year's theme was 'Restoring our waters'.
This years event was free to attend. It was the EPA's largest water event ever, with over 1250 attending.
To everyone who joined us: thanks for attending; thanks for your probing questions; thanks for your passion; thanks for caring about our waters. We can achieve more working together.
Special thanks to all our presenters and the team who worked behind the scenes to make sure this years conference happened.
For science and stories about water quality in Ireland, check out www.catchments.ie
On 17 and 18 June 2020 the EPA held its National Water Event as an online conference.
This year's theme was 'Restoring our waters'.
This years event was free to attend. It was the EPA's largest water event ever, with over 1250 attending.
To everyone who joined us: thanks for attending; thanks for your probing questions; thanks for your passion; thanks for caring about our waters. We can achieve more working together.
Special thanks to all our presenters and the team who worked behind the scenes to make sure this years conference happened.
For science and stories about water quality in Ireland, check out www.catchments.ie
On 17 and 18 June 2020 the EPA held its National Water Event as an online conference.
This year's theme was 'Restoring our waters'.
This years event was free to attend. It was the EPA's largest water event ever, with over 1250 attending.
To everyone who joined us: thanks for attending; thanks for your probing questions; thanks for your passion; thanks for caring about our waters. We can achieve more working together.
Special thanks to all our presenters and the team who worked behind the scenes to make sure this years conference happened.
For science and stories about water quality in Ireland, check out www.catchments.ie
This presentation was given at the 2019 Catchment Management Notwork meeting, which was held on the 11 October in Tullamore. All our local authorities and other bodies responsible for implementing the Water Framework Directive in Ireland attended to share knowledge and learn from each other.
This presentation was given at the 2019 Catchment Management Notwork meeting, which was held on the 11 October in Tullamore. All our local authorities and other bodies responsible for implementing the Water Framework Directive in Ireland attended to share knowledge and learn from each other.
This presentation was given at the 2019 Catchment Management Network meeting, which was held on the 11 October in Tullamore. All our local authorities and other bodies responsible for implementing the Water Framework Directive in Ireland attended to share knowledge and learn from each other.
This presentation was given on 17 July 2020 as part of the EPA's online Water Conference by Feargal Ó'Coigligh, Department of Housing Planning and Local Government.
On 17 and 18 June 2020 the EPA held its National Water Event as an online conference.
This year's theme was 'Restoring our waters'.
This years event was free to attend. It was the EPA's largest water event ever, with over 1250 attending.
To everyone who joined us: thanks for attending; thanks for your probing questions; thanks for your passion; thanks for caring about our waters. We can achieve more working together.
Special thanks to all our presenters and the team who worked behind the scenes to make sure this years conference happened.
For science and stories about water quality in Ireland, check out www.catchments.ie
On 17 and 18 June 2020 the EPA held its National Water Event as an online conference.
This year's theme was 'Restoring our waters'.
This years event was free to attend. It was the EPA's largest water event ever, with over 1250 attending.
To everyone who joined us: thanks for attending; thanks for your probing questions; thanks for your passion; thanks for caring about our waters. We can achieve more working together.
Special thanks to all our presenters and the team who worked behind the scenes to make sure this years conference happened.
For science and stories about water quality in Ireland, check out www.catchments.ie
On 17 and 18 June 2020 the EPA held its National Water Event as an online conference.
This year's theme was 'Restoring our waters'.
This years event was free to attend. It was the EPA's largest water event ever, with over 1250 attending.
To everyone who joined us: thanks for attending; thanks for your probing questions; thanks for your passion; thanks for caring about our waters. We can achieve more working together.
Special thanks to all our presenters and the team who worked behind the scenes to make sure this years conference happened.
For science and stories about water quality in Ireland, check out www.catchments.ie
This presentation was given at the 2019 Catchment Management Notwork meeting, which was held on the 11 October in Tullamore. All our local authorities and other bodies responsible for implementing the Water Framework Directive in Ireland attended to share knowledge and learn from each other.
This presentation was given at the 2019 Catchment Management Notwork meeting, which was held on the 11 October in Tullamore. All our local authorities and other bodies responsible for implementing the Water Framework Directive in Ireland attended to share knowledge and learn from each other.
This presentation was given at the 2019 Catchment Management Network meeting, which was held on the 11 October in Tullamore. All our local authorities and other bodies responsible for implementing the Water Framework Directive in Ireland attended to share knowledge and learn from each other.
On 17 and 18 June 2020 the EPA held its National Water Event as an online conference.
This year's theme was 'Restoring our waters'.
This years event was free to attend. It was the EPA's largest water event ever, with over 1250 attending.
To everyone who joined us: thanks for attending; thanks for your probing questions; thanks for your passion; thanks for caring about our waters. We can achieve more working together.
Special thanks to all our presenters and the team who worked behind the scenes to make sure this years conference happened.
For science and stories about water quality in Ireland, check out www.catchments.ie
This presentation was given at the 2019 Catchment Management Notwork meeting, which was held on the 11 October in Tullamore. All our local authorities and other bodies responsible for implementing the Water Framework Directive in Ireland attended to share knowledge and learn from each other.
This presentation was given at the 2019 Catchment Management Notwork meeting, which was held on the 11 October in Tullamore. All our local authorities and other bodies responsible for implementing the Water Framework Directive in Ireland attended to share knowledge and learn from each other.
The EPA Catchments Unit held its 2018 annual Catchment Management Network Meeting on 14 November. All our local authorities and many other public bodies are invited to this meeting to talk about how to protect and improve Ireland's waters.
The EPA Catchments Unit held its 2018 annual Catchment Management Network Meeting on 14 November. All our local authorities and many other public bodies are invited to this meeting to talk about how to protect and improve Ireland's waters.
Donal Daly, EPA Catchment Science and Management Unit outlines a possible approach to integrating Water Framework Directive and Biodiversity goals at the catchment scale.
The EPA Catchments Unit held its 2018 annual Catchment Management Network Meeting on 14 November. All our local authorities and many other public bodies are invited to this meeting to talk about how to protect and improve Ireland's waters.
This presentation was given at the 2019 Catchment Management Notwork meeting, which was held on the 11 October in Tullamore. All our local authorities and other bodies responsible for implementing the Water Framework Directive in Ireland attended to share knowledge and learn from each other.
This presentation was given at the 2019 Catchment Management Notwork meeting, which was held on the 11 October in Tullamore. All our local authorities and other bodies responsible for implementing the Water Framework Directive in Ireland attended to share knowledge and learn from each other.
This presentation was given at the 2019 Catchment Management Notwork meeting, which was held on the 11 October in Tullamore. All our local authorities and other bodies responsible for implementing the Water Framework Directive in Ireland attended to share knowledge and learn from each other.
This presentation was given at the 2019 Catchment Management Notwork meeting, which was held on the 11 October in Tullamore. All our local authorities and other bodies responsible for implementing the Water Framework Directive in Ireland attended to share knowledge and learn from each other.
This presentation was given at the Catchment Management Network meeting on February 3rd 2017. The Catchment Management Network consists of the EPA, all of Ireland's Local Authorities, and other public bodies involved in looking after Ireland's catchments, sub-catchments and water bodies. For more information about this work see www.catchments.ie
The Danube - Black Sea Strategic Partnership Program: Progress, Issues and Wa...Iwl Pcu
Jitendra Srivastava & Meeta Sehgal
Environmentally and Socially Sustainable Development Unit
Europe and Central Asia Region, World Bank
U.S.A.
Moldova, October 2006
This presentation was given at the Catchment Management Network meeting on February 3rd 2017. The Catchment Management Network consists of the EPA, all of Ireland's Local Authorities, and other public bodies involved in looking after Ireland's catchments, sub-catchments and water bodies. For more information about this work see www.catchments.ie
On 17 and 18 June 2020 the EPA held its National Water Event as an online conference.
This year's theme was 'Restoring our waters'.
This years event was free to attend. It was the EPA's largest water event ever, with over 1250 attending.
To everyone who joined us: thanks for attending; thanks for your probing questions; thanks for your passion; thanks for caring about our waters. We can achieve more working together.
Special thanks to all our presenters and the team who worked behind the scenes to make sure this years conference happened.
For science and stories about water quality in Ireland, check out www.catchments.ie
This presentation was given at the 2019 Catchment Management Notwork meeting, which was held on the 11 October in Tullamore. All our local authorities and other bodies responsible for implementing the Water Framework Directive in Ireland attended to share knowledge and learn from each other.
This presentation was given at the 2019 Catchment Management Notwork meeting, which was held on the 11 October in Tullamore. All our local authorities and other bodies responsible for implementing the Water Framework Directive in Ireland attended to share knowledge and learn from each other.
The EPA Catchments Unit held its 2018 annual Catchment Management Network Meeting on 14 November. All our local authorities and many other public bodies are invited to this meeting to talk about how to protect and improve Ireland's waters.
The EPA Catchments Unit held its 2018 annual Catchment Management Network Meeting on 14 November. All our local authorities and many other public bodies are invited to this meeting to talk about how to protect and improve Ireland's waters.
Donal Daly, EPA Catchment Science and Management Unit outlines a possible approach to integrating Water Framework Directive and Biodiversity goals at the catchment scale.
The EPA Catchments Unit held its 2018 annual Catchment Management Network Meeting on 14 November. All our local authorities and many other public bodies are invited to this meeting to talk about how to protect and improve Ireland's waters.
This presentation was given at the 2019 Catchment Management Notwork meeting, which was held on the 11 October in Tullamore. All our local authorities and other bodies responsible for implementing the Water Framework Directive in Ireland attended to share knowledge and learn from each other.
This presentation was given at the 2019 Catchment Management Notwork meeting, which was held on the 11 October in Tullamore. All our local authorities and other bodies responsible for implementing the Water Framework Directive in Ireland attended to share knowledge and learn from each other.
This presentation was given at the 2019 Catchment Management Notwork meeting, which was held on the 11 October in Tullamore. All our local authorities and other bodies responsible for implementing the Water Framework Directive in Ireland attended to share knowledge and learn from each other.
This presentation was given at the 2019 Catchment Management Notwork meeting, which was held on the 11 October in Tullamore. All our local authorities and other bodies responsible for implementing the Water Framework Directive in Ireland attended to share knowledge and learn from each other.
This presentation was given at the Catchment Management Network meeting on February 3rd 2017. The Catchment Management Network consists of the EPA, all of Ireland's Local Authorities, and other public bodies involved in looking after Ireland's catchments, sub-catchments and water bodies. For more information about this work see www.catchments.ie
The Danube - Black Sea Strategic Partnership Program: Progress, Issues and Wa...Iwl Pcu
Jitendra Srivastava & Meeta Sehgal
Environmentally and Socially Sustainable Development Unit
Europe and Central Asia Region, World Bank
U.S.A.
Moldova, October 2006
This presentation was given at the Catchment Management Network meeting on February 3rd 2017. The Catchment Management Network consists of the EPA, all of Ireland's Local Authorities, and other public bodies involved in looking after Ireland's catchments, sub-catchments and water bodies. For more information about this work see www.catchments.ie
Presentation: Romania Agricultural Pollution Control Project [4th Global Nitr...Iwl Pcu
Presentation given by Stefan Nicolau on behalf of the Romania Agricultural Pollution Control project at the 4th Nitrogen Conference, part of the Global Nitrogen Initiative.
Moldovan Experience with Nutrient Pollution Control in Agro-Processing Iwl Pcu
Dr. Alexandru Jolondcovschi, APCP Manager
Presented at the Black Sea – Danube Regional Conference on Nutrient Pollution Control in Chisinau, Moldova – October 2006
Uganda Country Experience Ecosystem-based Approaches to Climate Change Adapta...NAP Events
Presentation by: Muhammad Semambo
4a. Experience with ecosystem-based approaches under the Convention on Biological Diversity
The session will present findings from a synthesis report prepared by the CBD Secretariat on experiences with ecosystem-based approaches to climate change adaptation (EBA) and disaster risk reduction (Eco-DRR). It will provide opportunities for countries to share experiences and discuss ways to mainstream EBA and Eco-DRR into NAPs and other plans and strategies. Participants will be invited to take part in a group exercise to identify gaps and needs, as well as entry points and opportunities for integrating EBA.
Increasing the storage of carbon in the soil has been a controversial strategy for addressing climate change mitigation. What is the potential and why is there debate about this? How can we push beyond the debate to constructive action?
Lini Wollenberg, a Gund Fellow, is an anthropologist and natural resource management specialist concerned with rural livelihoods and the environment. She currently leads a research program on Low Emissions Agricultural Development for the CGIAR Research Program on Climate Change, Agriculture and Food Security (CCAFS), based at the University of Vermont. Her work seeks to identify options for reducing the impacts of agricultural development and land use on the climate, while also improving livelihoods for the poor in developing countries.
This presentation was given by Lini Wollenberg, CCAFS, on September 11, 2020 as part of the GundxChange Series.
Jenny Deakin from the EPA Catchments Unit gave a Teagasc Signpost Seminar on April 20 2021. The seminar covered water quality, focused on the agricultural sector, and the solutions needed to improve water quality, and new tools to target the right measure in the right place. This includes upgraded Pollution Impact Potential Maps for Nitrogen and Phosphorus, together with overland flow and focused delivery points.
On 25 November 2020 the EPA published Ireland’s Environment - An Integrated Assessment 2020 which provides an assessment of the overall quality of Ireland's environment, the pressures being placed on it and the societal responses to current and emerging environmental issues.
This plain English fact sheet outlines the work done by the EPA in monitoring Ireland’s rivers.
Ireland has more than 73,000 km of river channels. If placed end-to-end, they could encircle the Earth almost twice. Three-quarters of these channels are very small streams that typically flow into larger rivers.
Biological monitoring has been carried out in Irish rivers since 1971. The current national river monitoring programme covers more than 13,000 km of river channel.
The national monitoring programme is run by the EPA and focuses on the main river channels rather than the smaller streams. The programme includes more than 2,800 sites sampled for biology, with almost half of these being sampled for physical and chemical parameters.
This plain English fact sheet outlines the work done by the EPA in monitoring phytoplankton in Ireland's marine environment.
The EPA and the Marine Institute sample phytoplankton in estuaries and coastal waters around Ireland. They carry out sampling three times during the summer and once during winter. At each location, they take water samples just below the surface and above the seabed. They use the samples to assess how much phytoplankton is in the water and what species are present.
Phytoplankton are tiny, free-floating plants found suspended in the world’s oceans. Their name comes from Greek and means ‘plant drifter’. They are carried along by ocean currents and are usually found floating near the surface of the water. Like all plants they need sunlight to grow.
The main sources of nutrients around Ireland’s coast are discharges from wastewater treatment plants and run off from agricultural land. Phytoplankton in the estuaries and coastal waters around Ireland are monitored by the EnvironmentalProtection Agency (EPA) and the Marine Institute. They monitor phytoplankton to assess the quality (status) of our marine environment. They must do this as part of the requirements of the European Water Framework Directive.
This plain English fact sheet outlines the work done by the EPA in monitoring Ireland’s marine environment.
Ecologically healthy marine waters are a valuable natural resource. They support a rich and diverse range of ecosystems, habitats and species, and they are also a source of food – from wild fisheries and aquaculture. They are also important for recreational activities and tourism.
Transitional and coastal waters are assessed under the European Water Framework Directive (WFD) and the Marine Strategy Framework Directive (MSFD). Having coordinated frameworks for water quality for all the water bodies in Ireland, and across Europe, allows us to compare our results with other countries. It allows us to see what works to help us make sure all our water bodies achieve at least ‘good’ status, and no deterioration occurs.
This plain English fact sheet outlines the work done by the EPA in monitoring Ireland’s lakes.
A total of 225 lakes are currently included as part of the national surface waters monitoring programme run by the EPA, this covers around 80% of the surface area of all lakes in Ireland.
This includes:
• all lakes greater than 50 hectares
• lakes that are used for supplying drinking water
• lakes that are of regional, local or scientific interest
This Plain English fact sheet outlines the work done by the EPA in monitoring aquatic plants in Irish lakes.
Aquatic plants are good at showing if the quality of the water is good or bad and play an important role in lake ecology by providing food and a habitat for many smaller plants, animals and birds.
They also:
• provide shelter for young fish
• help to improve the clarity of the water
• help stabilise lake shore banks
• reduce the amount of sediment being suspended in the water
The Environmental Protection Agency (EPA) monitors these aquatic plants at more than 10,000 sites in over 200 lakes once every three years.
On 17 and 18 June 2020 the EPA held its National Water Event as an online conference.
This year's theme was 'Restoring our waters'.
This years event was free to attend. It was the EPA's largest water event ever, with over 1250 attending.
To everyone who joined us: thanks for attending; thanks for your probing questions; thanks for your passion; thanks for caring about our waters. We can achieve more working together.
Special thanks to all our presenters and the team who worked behind the scenes to make sure this years conference happened.
For science and stories about water quality in Ireland, check out www.catchments.ie
On 17 and 18 June 2020 the EPA held its National Water Event as an online conference.
This year's theme was 'Restoring our waters'.
This years event was free to attend. It was the EPA's largest water event ever, with over 1250 attending.
To everyone who joined us: thanks for attending; thanks for your probing questions; thanks for your passion; thanks for caring about our waters. We can achieve more working together.
Special thanks to all our presenters and the team who worked behind the scenes to make sure this years conference happened.
For science and stories about water quality in Ireland, check out www.catchments.ie
On 17 and 18 June 2020 the EPA held its National Water Event as an online conference.
This year's theme was 'Restoring our waters'.
This years event was free to attend. It was the EPA's largest water event ever, with over 1250 attending.
To everyone who joined us: thanks for attending; thanks for your probing questions; thanks for your passion; thanks for caring about our waters. We can achieve more working together.
Special thanks to all our presenters and the team who worked behind the scenes to make sure this years conference happened.
For science and stories about water quality in Ireland, check out www.catchments.ie
On 17 and 18 June 2020 the EPA held its National Water Event as an online conference.
This year's theme was 'Restoring our waters'.
This years event was free to attend. It was the EPA's largest water event ever, with over 1250 attending.
To everyone who joined us: thanks for attending; thanks for your probing questions; thanks for your passion; thanks for caring about our waters. We can achieve more working together.
Special thanks to all our presenters and the team who worked behind the scenes to make sure this years conference happened.
For science and stories about water quality in Ireland, check out www.catchments.ie
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
11. CatchmentCARE: improving water quality in cross-border catchments - Con McLaughlin / Andy Griggs
1. EPA NationalWater Event 2020 Online Conference
Restoring Our Waters
ImprovingWater Quality in cross border Catchments
18th June 202018 June 2020
2. • €13.8 million over 5 years to October 2022
• EU Programme for N. Ireland, Border Region & Western
Scotland
• Match funding kindly provided by the
Department of Housing, Planning and Local Government Department of Housing, Planning and Local Government
in Ireland and the
Department of Agricultural,Environment and Rural
Affairs in Northern Ireland
• CatchmentCARE is funded under Priority Axis 2 –
Environment,Priority 2b – Invest in Water Sector, Objective
2.4 – Improve freshwater quality in river basins
• I would like to credit our Project Partners for some of the
slides to follow
3. Project Outputs:
Establish 3 water quality improvement
projects
1. Arney catchment
(304km2)(304km2)
2. Blackwater catchment
(1,500km2)
3. Finn catchment
(494km2)
Install 50 groundwater monitoring
stations across the region
4. The Project will be delivered through a combination of . .
- policy actions
- catchment and water body actions
- enhancing the capacity of local stakeholders to
contribute to improvements in water quality
. . . very relevant for this mornings
‘Communities in Action’ theme
My colleague Andy Griggs, will focus on the
community aspect in the second half of this
presentation
5. Recent trends in water
quality at a glance . .
Mary Gurrie,EPA
Water Quality in Ireland 2013-2018
7. Scoping work package. .
Detailed‘story-maps’
which describe the
CatchmentCatchment
characterisations
can be found
on our project website ..
www.catchmentcare.eu
8. Loughs Agency are leading out on
• Water quality improvement schemes
to include in-stream and riparian
AT THE FINN . .
to include in-stream and riparian
improvements;
• Removal of barriers to migration
across three catchments;
• Investigate Chemical Export issue
and mitigating measures required to
address that;
• Sheep dipping and forestry have
been highlighted as areas for
mitigation.
9. Desk Study to
identify sites for
surveying
Survey sites and
complete data
Submit the NIS to
Create an NIS
(Natura Impact
Assessment).
Seek planning
permission /
Erect site notice
Identify the type
of tender
The approach required in the
Finn (Protected Area):
• Natura Impact Statement
• Notifiable Actions Consent
• Planning Permission Docs
• Site Location and Layout maps
complete data
analysis
Prioritise areas in
terms of need for
enhancement
works.
Site Walkovers to
identify action for
works.
Meet landowners
re potential plans
/ gain landowner
permission.
Determine the
definite course of
action & methods
of works.
Submit the NIS to
NPWS
of tender
documents
needed for works
Tender process /
select successful
contractor +
commence works
Monitoring of
works delivery.
• Site Location and Layout maps
• Elevation Blueprints
• Work Specifications
• Tender Documents
• Landowner permissions
• Landowner Appeasement
12. AT THE ARNEY:
The Groundwater Team are progressing . .
Data loggers deployed at/near groundwater risings –
Electrical conductivity,temperature,water level at 11
sites including Marble Arch and Cladagh river with 5
other sites to be monitored.other sites to be monitored.
Possible drilling locations – Mill street (NW of
catchment in sandstone)
Marble Arch caves – provides very good opportunity for
linking with UNESCO Geopark
GW Team are collaborating with one of our
community groups –on dye tracing in karst locations
which has great potential
13. AT THE ARNEY:
IFI are progressing various
In-stream & Riparian
works in conjunction with
landowners;
Working through AA
Screening and liaising with
DAERA/ DfI/ OPW on
consents required
Working with Community
Groups and with the GW
Team;
14. AT THE
BLACKWATER:
ABC / IFI are progressing
various In-stream & Riparian
works in conjunction withworks in conjunction with
landowners
Also liaising with DAERA/ DfI/
OPW on consents required
ABC are working with the
farming community (soil
sampling) in conjunction with
AFBI
15. Evaluation of Farm Nutrient Management Practices
Farm scale study,agronomic trial,Farmyard surveys,
soil P
Main driver - changes to zero or low P inputs
Evaluation of the Lag-Time in Achieving
AT THE BLACKWATER:
Agri-food & Biosciences Institute (Afbi) work
on 17 selected farms includes . .
Evaluation of the Lag-Time in Achieving
WFD Nutrient Targets for waterbodies
Catchment modelling,Lake sediment coring/sediment
re-suspension in conjunction with UU
Evaluation of the cost effectiveness and cost benefit
of achieving theWFD objectives
Farm optimisation modelling
Harmonizing the Soil Phosphorus Index Systems
Examining the relationship between Olsen and Morgan
16. Harmonizing the Soil Phosphorus Index Systems
10% (56 samples) were sent to Teagasc Johnstown
Castle for quality control,
To ensure that the AFBI and Teagasc analyses areTo ensure that the AFBI and Teagasc analyses are
consistent
200 samples sent for textural analysis to indicate
whether the relationship between Olsen and Morgan
Phosphorus was influenced by soil type.
17. Afbi are also delivering work
with willows including:
Potential for mitigation of
diffuse pollution
In conjunction with UU, point
source discharge fromWWtWs
- construction of 3no src
willow enhancements to
wastewater treatment
schemes within sensitive
catchments
18. Paper to follow!
An assessment of
stakeholder
Sub – catchment approx. 22ha
Afbi) work on diffuse pollution includes . .
stakeholder
commitment to the
principle of SRC
willow planting
and how this fits
with national
strategies
19. Paper to follow!
An assessment of
stakeholder
commitment to the
principle of SRC willow
Afbi) work on diffuse pollution includes . .
principle of SRC willow
planting and how this
fits with national
strategies
Separate Conference
held in Dundalk at
5th March 2020
see presentation on
www.catchmentcare.eu
20. Afbi) work on diffuse pollution
includes . .
Paper to follow!
An assessment of stakeholder
commitment to the principle ofcommitment to the principle of
SRC willow planting and how this
fits with national strategies
Positive interest in a Conference
held in Dundalk at 5th March
2020,see presentation on
www.catchmentcare.eu
21. Ulster University (UU) are progressing work:
1) on the feasibility of lake remediation via phosphorus-fixing. .
Draft reports, (Risk assessment & Ecological effects) of the
of aluminium and iron salts on lakes, submitted to the
two environment agencies / WIP!
2) with AFBI on the hydrological connectivity & point source
pollution at Liscooley (Finn) & Cavanagrow (Blackwater)
Monitoring up-stream & down-stream of discharge points
Biological monitoring - Diatom and Chlorophyll-A
Concrete block with tiles u/p & d/s - Algal growth substrate
BenthoTorch
Soluble Reactive Phosphorus (SRP)
22. Ulster University (UU) are working (with Afbi) on the evaluation of lagtime
in achievingWFD nutrient targets in Lakes and Rivers
This work package seeks to establish the extent of the internal phosphorus load to
Upper and Lower Lough Macnean from sediment and suspended sediment.
The work will have two main focuses:
Analysis of the phosphorus fractions of cores taken from the lakes in order to
establish phosphorus concentrations present & dated in order to establish a
timescale for recovery for the lakes
Deployment of sediment traps in the lakes to evaluate the volume of suspended
sediment present in the lakes during differing weather conditions.
Coring sites at Lower &
Upper Lough Macnean
23. Provide
recommendat
ions
Assist with
X border representation from:
• Loughs Agency (Chair)
• DCC
Project Governance –
Steering Group with 3 Sub Committees
WFD
Sub-
Committ
ee
Identify issues
and solutions
Liaise with
other sub-
committees
Act as a
facilitator to
both
jurisdictions
Assist with
knowledge
transfer and
best practice
• DCC
• EPA
• DAERA
• IFI
• DoAFM
(Forestry/WFD/Agricultural)
• DoHPLG (Water Advisory Unit)
• OPW
• GSI
• DfI Rivers
WFD Co-ordination Sub Committee
24. Thank you –
I’ll hand you over to Andy
Griggs now who will focus
on Community engagement
for the remainder of this
presentation
25. • Plan and execute a programme of activities that satisfies the
identified needs of the stakeholder groups
• Engage landowners,farmers and local interest groups to develop a
shared understanding of the challenges facing individual catchments
in order to then agree specific actions and implement them
CatchmentCARE Communication Objectives
in order to then agree specific actions and implement them
• Maximise public interest in the work and ultimately to heighten
awareness of water quality issues and management.
• Inform relevant regional and national organisations of the value of
the work, particularly to encourage collaboration with organisations
that have an environmental or technical interest
• Inform government,academia and industry of the value and
availability of the information and to encourage these sectors to use
the new data in improving environmental management in the project
area.
26. 1. Press Releases
2. Events
3.Website – www.catchmentcare.eu
4. Social media presence – Facebook / Twitter / Instagram /
You Tube
CatchmentCARE Communication Methods
You Tube
5. Community engagement events
6. Newsletters
7. Brochure
8. Factsheet
9 Fliers
10. Info graphic(s)
11. Resources for schools
12. Resources for farmers and industry
27. • Support communities to take innovative approaches
to looking after and caring for their local river
systems including associated lakes.
• 17 projects funded across the 3 Catchments in 2019
Community Incentive Scheme (CIS)
• 17 projects funded across the 3 Catchments in 2019
• CatchmentCARE staff helping to develop and
deliver project in partnership with groups –
including procurement process
• Access projects,Education programmes,Training
for group members, Equipment supply,
Interpretation,Community action days, Bioblitzes all
funded
• Successful element of CC to date with huge potential
for positive legacy to the project
30. Education Programmes
- Successful pilot education programme rolled
out in 2019 (April – June), 8 schools in 3
Catchments
- 200 pupils involved / 17 teachers & assistants- 200 pupils involved / 17 teachers & assistants
- 4 Catchment Films developed with Drone
Footage on local rivers.All narrated by the
children as part of their ‘River Journey’ – can be
viewed on CatchmentCAREYouTube Channel
or www.facebook.com/catchmentCARE
- Further education programmes developed for
2020 - teacher training included
31. Community Engagement Sub Committee
- The project has a Community sub Committee which meets on a bi-annual basis
- Its role is to provide strategic advice to the project team on the direction and implementation of
community engagement work across the three catchments and to share any new knowledge
gained through the course of the project with NGOs and the community sectorgained through the course of the project with NGOs and the community sector
- The sub committee is made up of the statutory,Community / NGO and local government sectors
- Included on the current committee are representatives from LAWCO, NIEA, River Blackwater
Catchment Trust, IFA, UFU, NI Forest Service,IFI, Mid Ulster Council,Monaghan County Council,
Ballinderry Rivers Trust, Donegal County Council & Armagh City, Banbridge & Craigavon Borough
Council.