1. Which of the following proteins does NOT directly interact with TFIID? a.Co-activator protein b.Repressor protein c.Mediator d.Activator protein e.RNA polymerase f. Histone deacetylase 2. maintenance methykation of DNA is rare and highly reguated a.true b.false Solution f. Histone deacetylase.....has nothing to dowith transcriptional matchinery .... a.true.... Because methylation is epigentic control resulting in differentiating cell types Hope it helps regards.