This document outlines the scientific method and the nature of science. It discusses that science is a way to propose answers about natural events through observation and understanding the natural world using a problem-solving process called the scientific method. The scientific method involves making observations, forming a hypothesis, testing the hypothesis through experimentation, collecting and analyzing data, drawing conclusions, and communicating results. Theories and laws are also discussed as explanations for phenomena based on experimentation and observation.
The Scientific MethodSteps in the Scientific MethodThere is a .docxssusera34210
The Scientific Method
Steps in the Scientific Method
There is a great deal of variation in the specific techniques scientists use explore the natural world. However, the following steps characterize the majority of scientific investigations:
Step 1: Make observations
Step 2: Propose a hypothesis to explain observations
Step 3: Test the hypothesis with further observations or experiments
Step 4: Analyze data
Step 5: State conclusions about hypothesis based on data analysis
Each of these steps is explained briefly below, and in more detail later in this section.
Step 1: Make observations
A scientific inquiry typically starts with observations. Often, simple observations will trigger a question in the researcher's mind.
Example: A biologist frequently sees monarch caterpillars feeding on milkweed plants, but rarely sees them feeding on other types of plants. She wonders if it is because the caterpillars prefer milkweed over other food choices.
Step 2: Propose a hypothesis
The researcher develops a hypothesis (singular) or hypotheses (plural) to explain these observations. A hypothesis is a tentative explanation of a phenomenon or observation(s) that can be supported or falsified by further observations or experimentation.
Example: The researcher hypothesizes that monarch caterpillars prefer to feed on milkweed compared to other common plants. (Notice how the hypothesis is a statement, not a question as in step 1.)
Step 3: Test the hypothesis
The researcher makes further observations and/or may design an experimentto test the hypothesis. An experiment is a controlled situation created by a researcher to test the validity of a hypothesis. Whether further observations or an experiment is used to test the hypothesis will depend on the nature of the question and the practicality of manipulating the factors involved.
Example: The researcher sets up an experiment in the lab in which a number of monarch caterpillars are given a choice between milkweed and a number of other common plants to feed on.
Step 4: Analyze data
The researchersummarizes and analyzes the information, or data, generated by these further observations or experiments.
Example: In her experiment, milkweed was chosen by caterpillars 9 times out of 10 over all other plant selections.
Step 5: State conclusions
The researcher interprets the results of experiments or observations and forms conclusions about the meaning of these results. These conclusions are generally expressed as probability statements about their hypothesis.
Example: She concludes that when given a choice, 90 percent of monarch caterpillars prefer to feed on milkweed over other common plants.
Often, the results of one scientific study will raise questions that may be addressed in subsequent research. For example, the above study might lead the researcher to wonder why monarchs seem to prefer to feed on milkweed, and she may plan additional experiments to explore this question. For example, perhaps the milkweed has higher ...
Introduc on to Science
12
The Scientific Method
Observations
Variables
Controls
Data Analysis
Calculations
Data Collection
Percent Error
Scientific Reasoning
Writing a Lab Report
Socrates (469 B.C. - 399 B.C.), Plato (427 B.C. - 347 B.C.), and Aristotle (384
B.C. - 322 B.C.) are among the most famous of the Greek philosophers
(Figure 1). Plato was a student of Socrates, and Aristotle was a student of Pla-
to. These three philosophers are considered to be the greatest thinkers of
their time.
Aristotle’s views on science profoundly shaped medieval academics, and his
influence extended into the Renaissance (14th - 16th century). His opinions
were the authority on science well into the 1300s. Unfortunately, the philoso-
pher’s method was logical thinking and did not involve making direct observa-
tions on the natural world. As a result, many of Aristotle’s opinions were incor-
rect. Although he was extremely intelligent, he used a method for determining
the nature of science that was insufficient for the task. For example, in Aris-
totle’s opinion, men were bigger than women. Therefore, he made the de-
duction that men would have more teeth than women. It is assumed that he
never actually looked into the mouths of both men and women and counted
their teeth. If he had, he would have found that males and females have ex-
actly the same number of teeth (Figure 2).
In the 16th and 17th centuries, innovative thinkers began developing a new
way to investigate the world around them. They were developing a method
that relied upon making observations of phenomena and trying to explain
why that phenomena occurred. From these techniques, the scientific method
was born. The scientific method is a process of investigation that involves
Figure 1: Neoclassical statue
of ancient Greek philosopher,
Plato, in front of the Academy
of Athens in Greece.
Figure 2: Humans—male and
female—have 20 baby teeth
and 32 permanent teeth.
13
experimentation and observation to acquire new knowledge, solve problems, and answer questions. Scien-
tists eventually perfected the methods and reduced it to a series of steps (Figure 3).
Today, the scientific method is used as a systematic approach to solving problems. Science begins with ob-
servations. Once enough observations or results from preliminary library or experimental research have been
collected, a hypothesis can be constructed. Experiments then either verify or disprove the hypothesis. If
enough evidence can support a hypothesis, the hypothesis can become a theory, or proven fact. Theories
can be further refined by other hypotheses and experimentation. An example of this is how we further refine
our knowledge of germ theory by learning about specific pathogens. A scientific law is a summary of observa-
tions in which there are no current exceptions using the most recent technology. It can be a general state-
ment, like the Law of Gravity (what goes up m.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
The Scientific MethodSteps in the Scientific MethodThere is a .docxssusera34210
The Scientific Method
Steps in the Scientific Method
There is a great deal of variation in the specific techniques scientists use explore the natural world. However, the following steps characterize the majority of scientific investigations:
Step 1: Make observations
Step 2: Propose a hypothesis to explain observations
Step 3: Test the hypothesis with further observations or experiments
Step 4: Analyze data
Step 5: State conclusions about hypothesis based on data analysis
Each of these steps is explained briefly below, and in more detail later in this section.
Step 1: Make observations
A scientific inquiry typically starts with observations. Often, simple observations will trigger a question in the researcher's mind.
Example: A biologist frequently sees monarch caterpillars feeding on milkweed plants, but rarely sees them feeding on other types of plants. She wonders if it is because the caterpillars prefer milkweed over other food choices.
Step 2: Propose a hypothesis
The researcher develops a hypothesis (singular) or hypotheses (plural) to explain these observations. A hypothesis is a tentative explanation of a phenomenon or observation(s) that can be supported or falsified by further observations or experimentation.
Example: The researcher hypothesizes that monarch caterpillars prefer to feed on milkweed compared to other common plants. (Notice how the hypothesis is a statement, not a question as in step 1.)
Step 3: Test the hypothesis
The researcher makes further observations and/or may design an experimentto test the hypothesis. An experiment is a controlled situation created by a researcher to test the validity of a hypothesis. Whether further observations or an experiment is used to test the hypothesis will depend on the nature of the question and the practicality of manipulating the factors involved.
Example: The researcher sets up an experiment in the lab in which a number of monarch caterpillars are given a choice between milkweed and a number of other common plants to feed on.
Step 4: Analyze data
The researchersummarizes and analyzes the information, or data, generated by these further observations or experiments.
Example: In her experiment, milkweed was chosen by caterpillars 9 times out of 10 over all other plant selections.
Step 5: State conclusions
The researcher interprets the results of experiments or observations and forms conclusions about the meaning of these results. These conclusions are generally expressed as probability statements about their hypothesis.
Example: She concludes that when given a choice, 90 percent of monarch caterpillars prefer to feed on milkweed over other common plants.
Often, the results of one scientific study will raise questions that may be addressed in subsequent research. For example, the above study might lead the researcher to wonder why monarchs seem to prefer to feed on milkweed, and she may plan additional experiments to explore this question. For example, perhaps the milkweed has higher ...
Introduc on to Science
12
The Scientific Method
Observations
Variables
Controls
Data Analysis
Calculations
Data Collection
Percent Error
Scientific Reasoning
Writing a Lab Report
Socrates (469 B.C. - 399 B.C.), Plato (427 B.C. - 347 B.C.), and Aristotle (384
B.C. - 322 B.C.) are among the most famous of the Greek philosophers
(Figure 1). Plato was a student of Socrates, and Aristotle was a student of Pla-
to. These three philosophers are considered to be the greatest thinkers of
their time.
Aristotle’s views on science profoundly shaped medieval academics, and his
influence extended into the Renaissance (14th - 16th century). His opinions
were the authority on science well into the 1300s. Unfortunately, the philoso-
pher’s method was logical thinking and did not involve making direct observa-
tions on the natural world. As a result, many of Aristotle’s opinions were incor-
rect. Although he was extremely intelligent, he used a method for determining
the nature of science that was insufficient for the task. For example, in Aris-
totle’s opinion, men were bigger than women. Therefore, he made the de-
duction that men would have more teeth than women. It is assumed that he
never actually looked into the mouths of both men and women and counted
their teeth. If he had, he would have found that males and females have ex-
actly the same number of teeth (Figure 2).
In the 16th and 17th centuries, innovative thinkers began developing a new
way to investigate the world around them. They were developing a method
that relied upon making observations of phenomena and trying to explain
why that phenomena occurred. From these techniques, the scientific method
was born. The scientific method is a process of investigation that involves
Figure 1: Neoclassical statue
of ancient Greek philosopher,
Plato, in front of the Academy
of Athens in Greece.
Figure 2: Humans—male and
female—have 20 baby teeth
and 32 permanent teeth.
13
experimentation and observation to acquire new knowledge, solve problems, and answer questions. Scien-
tists eventually perfected the methods and reduced it to a series of steps (Figure 3).
Today, the scientific method is used as a systematic approach to solving problems. Science begins with ob-
servations. Once enough observations or results from preliminary library or experimental research have been
collected, a hypothesis can be constructed. Experiments then either verify or disprove the hypothesis. If
enough evidence can support a hypothesis, the hypothesis can become a theory, or proven fact. Theories
can be further refined by other hypotheses and experimentation. An example of this is how we further refine
our knowledge of germ theory by learning about specific pathogens. A scientific law is a summary of observa-
tions in which there are no current exceptions using the most recent technology. It can be a general state-
ment, like the Law of Gravity (what goes up m.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
2. What is Science
SCIENCE IS…..
a way in which answers related to NATURAL events
are proposed
a way in which people can learn and UNDERSTAND
events in the NATURAL WORLD.
based on OBSERVABLE EVENTS
a study of the NATURAL WORLD
a method of DISCOVERY and UNDERSTANDING
by using a PROBLEM SOLVING process called
the????
3. 6 Steps to the Scientific Method
1. Make an observation
2. Form a hypothesis
3. Test the hypothesis
4. Collect, Organize and Analyze the
Data
5. Draw Conclusions
6. Communicate the results
4. Step 1: Observations
Observations based on senses or tools
Sight, Smell, Touch etc.
Observations of natural events usually
raise a question
Why did the water rise when the candle went
out?
Research is usually done to help find out
more about the question raised
5. Step 2: Form A Hypothesis
Based on your observation a Hypothesis is
formed that tries to explain your observation or
answer your question
A hypothesis tries to predict or determine the
outcome of your experiment even before the
experiment is done
Predictions usually stated in an “if ….. Then” statement. Ex:
If I drop a rock then it will fall down toward the ground
HYPOTHESIS MUST BE TESTABLE!
6. Step 3: Test the Hypothesis
Controlled Experiments are used to test a
hypothesis
A controlled experiment is an experiment that
tests only one factor at a time by
a control group is compared with an experimental
group. Variables are not changed in the Control
Group.
Control groups allows you to see if a change in a
variable creates an observed outcome by
comparing the control group with the exp gp
A variable is a factor that changes in a controlled
experiment. Variables are changed in the Exp
Group AND SERVE AS THE FACTOR TESTED
7. VARIABLES
INDEPENDENT
The variable being changed in the experiment
DEPENDENT
The variable that responds to the changed
independent variable
The variable being measured
EX: growing plants with different amounts
of fertilizer
8. Step 3 Continued
Scientists try to design experiments that will clearly
show whether a particular VARIABLE caused an
observed outcome
IF IT CANNOT BE OBSERVED THEN IT CANNOT
BE TESTED!!!
Can we test if a comet impact kill the dinosaurs? Why or Why
Not?
Sometimes models are used to represent a real
object
Used when it is difficult to control all of the variables or not
possible to test “the real thing”
10. Step 4: Collect, Organize &
Analyze Data
Data collected from experiments
Data is defined as: recorded observations or
measurements (qualitative = description, quantitative
= number data)
Based on observations
Utilize tools or senses: sight, smell, temperature
change etc.
Data is organized in tables, charts and graphs
so that it can be more easily analyzed
11. Step 5: Draw Conclusions
Scientists decide whether the results of
the experiment support a hypothesis.
When the hypothesis is not supported by
the tests the scientist must find another
explanation for what they have observed
NO EXPERIMENT IS A FAILURE: All
experiments are observations of real events
12. Step 6: Communicate the
Results
Results must be communicated in the form
of a written paper or presentation
Communication helps other scientists
performing the same experiments to see if
the results of your experiment are the
same as their results
Helps people see if results are repeatable!
13. Theories
Theories are explanations for some
phenomena based on observation,
experimentation, and reasoning.
BASED ON MANY EXPERIMENTS
Experiments that explain a theory MUST
be repeatable
You must be able to predict from a
theory
14. LAWS
Laws are summaries of many
experimental results and
observations
Laws are not the same as theories
because laws tell only what happens,
not why it happens.
15. Pure Science
PURE SCIENCE
Pure Science: An attempt to learn more about the world
or the continuing search for scientific knowledge.
pure science is done by scientists or people with
inquisitive minds
involves experimentation, observations, questioning and
research
involves technology
16. Technology
Technology: An application of science to meet the needs of society
engineers, inventors and creative people apply scientific knowledge
to build new “things” or tools
new technology can lead to new scientific discoveries
ex: we could not learn about cells before the invention of the
microscope
Question: How does science lead to new technology
and how does technology add to our scientific
understanding of the natural world?
