brief view of genome annotation.

1.  In order to make use of the genome
sequence, we need to understand all of
its components. Assigning identities and
functions to sequences within the genome
is called genome annotation.

2. Genome sequencing helps in:
• identifying new genes (“gene discovery”)
• looking at chromosome organization and
structure
• finding gene regulatory sequences
• comparative genomics
These in turn lead to advances in:
•medicine
•agriculture
•biotechnology
•understanding evolution and other basic
science questions

5. 1. Identifying portions of the
genome that do not code for
proteins
2. Identifying elements on the
genome, a process called gene
prediction.
3. Attaching biological information
to these elements.

18. Despite good progress in identifying both
protein coding and non-protein coding
genes, much work remains to be done
before even the best-studied genomes are
fully annotated. For the higher eukaryotes,
only a tiny percentage of features such as
TFBSs, CRMs, and other non-gene features
have so far been indentified.
Genome Annotation—much work remains