Emergencies Caused By Psychiatric Drugs

Emergency caused by psychiatric medications side effects ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

SEROTONIN SYNDROME EMERGENCY IN PSYCHIATRY

DANGERS OF SEROTONIN SYNDROME ,[object Object],[object Object]

Mild Serotonin Syndrome ,[object Object],[object Object]

Increase serotonin synthesis ,[object Object]

Decrease serotonin metabolism ,[object Object]

Increase serotonin release ,[object Object],[object Object],[object Object]

Inhibit serotonin uptake ,[object Object],[object Object],[object Object],[object Object],[object Object]

Serotonin receptor agonists ,[object Object],[object Object],[object Object]

Nonspecific increase in serotonin levels ,[object Object],[object Object],[object Object],[object Object]

Risk of using Paroxetine (Paxil) ,[object Object]

Behavioral symptoms of serotonin syndrome ,[object Object],[object Object],[object Object],[object Object]

Autonomic symptoms of serotonin syndrome ,[object Object],[object Object],[object Object],[object Object],[object Object]

Neuromuscular symptoms of serotonin syndrome ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Diseases predisposing to serotonin syndrome ,[object Object],[object Object],[object Object],[object Object]

Treatment of serotonin syndrome ,[object Object],[object Object]

Medications of serotonin syndrome ,[object Object],[object Object],[object Object]

Treament of severe serotonin syndrome ,[object Object],[object Object]

TREATMENT OF SEROTONIN SYNDROME Refractory or severe cases Cryoheptadine 4 mg PO q 6 hrs Propranolol (Inderal) a mg IV q 30-60 min or 40mg PO q 6 hrs Methysergide (Sansert), 2 mg PO TID Lorazepam, 1 to 3 mg IV q 20-30 min up to 16 mg per day Mild cases Lorazepam (Ativan) 0.5-1.0 mg orally q 4-6 h Cryoheptadine (Periactin), 4 mg PO q6 h

EMERGENCIES CAUSED BY PSYCHIATRIC DRUGS Neuroleptic Malignant Syndrome

DRUGS CAUSING NMS ,[object Object],[object Object]

Differences in manifestations of NMS from serotonin syn ,[object Object],[object Object],[object Object]

Similarities of NMS and serotonin syndrome ,[object Object],[object Object]

Extra pyramidal Reactions Difficult to treat Involuntary movements of face, trunk and extremities -often irreversible c Tardive dyskinesia Antihistamines Anticholineric Inability to sit still C Akinesia Beta blockers Inability to sit still B Akathisia Anticholinergic Rigidity, decreased movements, abnormalities in gait B Parkinsonism Antihistamines Anticholinergic Neck and facial muscle spasm; Oculogyric crisis a Dystonia Treatment Symptoms Ac Ch Condition

Clinical manifestations of Dystonia ,[object Object],[object Object],[object Object],[object Object]

Clinical manifestations of Parkinsonism reaction ,[object Object],[object Object],[object Object],[object Object],[object Object]

Clinical manifestations of Akathisia ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Clinical manifestations of Akinesia ,[object Object],[object Object],[object Object]

Clinical Manifestations of Tardive dyskinesia ,[object Object],[object Object],[object Object],[object Object],[object Object]

Emergency caused by the use of tricyclics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Priapism- an emergency caused by Trazodone ,[object Object],[object Object],[object Object]

Anticholinergic syndrome ,[object Object],[object Object],[object Object],[object Object]

Hyper adrenergic crisis ,[object Object],[object Object],[object Object]

Lithium toxicity ,[object Object],[object Object]

Conclusion ,[object Object],[object Object]

Syndromes associated with the use of psychotherapeutic agents ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Emergencies Caused By Psychiatric Drugs

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Emergencies Caused By Psychiatric Drugs