Carnegie Mellon University researchers are advancing strategic reasoning and machine learning through high-performance computing, particularly focusing on decision-making under imperfect information, as exemplified by their work with poker as a benchmark. The researchers utilize novel algorithms to improve strategic reasoning capabilities in business contexts, indicating future applications in areas such as automated negotiation and strategic pricing. The discussion highlights the collaboration with Hewlett Packard Enterprise and the significant computational resources required to achieve superhuman-level performance in strategic reasoning tasks.