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SHREE MEDICAL AND TECHNICAL COLLEGE
BHARATPUR -12, GONDRANG
Presentation on Erythropoietin
PRESENTED BY:
SANJAY KUMAR YADAV
ROLL NO.: 22 (5th sem.)1/18/2020 0sanjay k. yadav
INTRODUCTION
Erythropoietin is a Hormone.
Also called Epo.
Produced by kidney.
By which stimulation of red-bone marrow to
produce erythrocytes ( RBCs ).
RBCs transport oxygen throughout the body.
Finally , prevents from the anemia, hypoxia etc.
1/18/2020 1sanjay k. yadav
REGULATION
1/18/2020 2sanjay k. yadav
DRUGS
Epo drugs are used for treatment of
chemotherapy-induced anemia,
Anemia is common side effect occuring due to
chemotheraphy of ESRD, cancer and HIV.
Forms of Epo such as epoetin alfa, epoetin beta,
epoetin omega, epoetin delta, derbepoetin alfa.
1/18/2020 3sanjay k. yadav
DOSES
 ANEMIA ASSOCIATED WITH CKD:
----Adult: Initial dose: 50 to 100 units/kg IV or subcutaneously 3
times a week
----Pediatric (1 Month to 16 Years): Initial dose: 50 units/kg IV or
subcutaneously 3 times a week
 Conditions:
----If hemoglobin increases by more than 1 g/dL in 2 weeks, reduce dose
by 25%
----If hemoglobin has not increased by more than 1 g/dL after 4 weeks
of therapy, increase dose by 25%.
1/18/2020 4sanjay k. yadav
Storage conditions: -Protect from light.
-Store at 2 to 8C. - Do not freeze.
Other conditions:
-Do not dilute.
-Do not shake.
-Allow this drug to reach room temperature before
injecting.
- Do not use preservative-free vials.
1/18/2020 5sanjay k. yadav
1/18/2020 6sanjay k. yadav

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Erythropoietin

  • 1. SHREE MEDICAL AND TECHNICAL COLLEGE BHARATPUR -12, GONDRANG Presentation on Erythropoietin PRESENTED BY: SANJAY KUMAR YADAV ROLL NO.: 22 (5th sem.)1/18/2020 0sanjay k. yadav
  • 2. INTRODUCTION Erythropoietin is a Hormone. Also called Epo. Produced by kidney. By which stimulation of red-bone marrow to produce erythrocytes ( RBCs ). RBCs transport oxygen throughout the body. Finally , prevents from the anemia, hypoxia etc. 1/18/2020 1sanjay k. yadav
  • 4. DRUGS Epo drugs are used for treatment of chemotherapy-induced anemia, Anemia is common side effect occuring due to chemotheraphy of ESRD, cancer and HIV. Forms of Epo such as epoetin alfa, epoetin beta, epoetin omega, epoetin delta, derbepoetin alfa. 1/18/2020 3sanjay k. yadav
  • 5. DOSES  ANEMIA ASSOCIATED WITH CKD: ----Adult: Initial dose: 50 to 100 units/kg IV or subcutaneously 3 times a week ----Pediatric (1 Month to 16 Years): Initial dose: 50 units/kg IV or subcutaneously 3 times a week  Conditions: ----If hemoglobin increases by more than 1 g/dL in 2 weeks, reduce dose by 25% ----If hemoglobin has not increased by more than 1 g/dL after 4 weeks of therapy, increase dose by 25%. 1/18/2020 4sanjay k. yadav
  • 6. Storage conditions: -Protect from light. -Store at 2 to 8C. - Do not freeze. Other conditions: -Do not dilute. -Do not shake. -Allow this drug to reach room temperature before injecting. - Do not use preservative-free vials. 1/18/2020 5sanjay k. yadav

Editor's Notes

  1. End stage renal diseases, also used in neural diseases, wound healing
  2. CHRONIC KIDNEY DISEASE
  3. 0.9% sodium chloride injection, USP, with benzyl alcohol 0.9% (bacteriostatic saline) in a 1:1 ratio using aseptic technique at the time of administration.