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NANO: TECHNOLOGY,
MATERIALS & APPLICATIONS
Introductory Lecture from Shah & Schulman Nano Technology Centre
Dharmasinh Desai University, Nadiad
Prof. Samirsinh P Parmar
under the Guidance of Prof. A.D.Shukla
Mail: samirddu@gmail.com
Asst. Professor, Department of Civil Engineering,
Faculty of Technology,
Dharmasinh Desai University, Nadiad-387001
Gujarat, INDIA
T
opics Covered
• Introduction
• Definition
• History
• Timeline
• Tools & techniques
• ▫ Carbon nanotubes
• ▫ Nanorods
• ▫ Nanobots
• Approaches used
• ▫ Top-down
• ▫ Bottom-up
• Materials used
• Application
• ▫ Drugs
• ▫ Fabrics
• ▫ Mobiles
• ▫ Electronics
• ▫ Computers
• ▫ Other uses
• Nanotechnology in INDIA
• Possibilities for future
• Pitfalls of nanotechnology.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
2
Defination
• Nanotechnology is the study
of manipulating matter on an
atomic scale.
• Nanotechnology refers to the
constructing and engineering of
the functional systems at very micro
level or we can say at atomic level.
• A Nanometer is one billionth
of a meter, roughly the width of
three or four atoms. The average
human hair is about 25,000
nanometers wide.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
3
Nanomaterials:
Materials consisting of particles of the size of nanometer
Volume = Surface Area * Thickness
❖ For a given volume:
Surface area Thickness
➢More atoms at surface than in the interior
➢Extraordinary activity
SCOPE: DEFINITION
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
4
Nanomaterials: Features
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
5
➢Synergistic combinations of materials of different kinds & characteristics
is possible through nanotechnology
Coatings, Films
10 nm
Homogeneous
Surface modification
Size Reduction
1 m
1 cm
+
Compatibility
Huge interfaces
Solid Liquid
solution
Inorganic
nanoparticles
in a liquid
media
Synthesis of Nanomaterials: Ex-situ
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
6
TiO2 TiO2
-
-
-
-
-
-
TiO2
TiO2
-
-
-
-
-
-
10 nm
Polymerization
Monomer
Monomer
Polymer
Surfactant
-
-Radical
Polymerization 100 µm
Grinding
Latex Fe2O3-Particles
Fe2O3-Particles
Latex
bead
Pre-treatment
Copolymer
layer
Encapsulated particle
Amphiphilic
molecule
➢ Ex-situ synthesis of nanomaterials involves number of steps
Polymer encapsulated nanomaterials used for targeted delivery of drugs- good example
of ex-situ synthesis
Synthesis of Nanomaterials : In-situ
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
7
Metal salt + Monomer
Adopting in-situ approach of synthesizing nanomaterials reduces
number of steps involved and hence simple process !
Nanocomposite
1. Hydrolysis
2. Polymerization
0 - D
1 - D
2 - D
Dimension
Thermal conductivity is more prominent in 1-D & 2-D nanomaterials
Thermal conductivity of C nanotubes (2-D nanomaterial) = 3000 Wm-1K-1; Copper (bulk) = 400 Wm-1K-1
Structure of Nanomaterials: Size and Shape
3 - D
Bulk
x , y , z
Nanocomposite
thick film
Rods
Wires
Tubes
Nanofilms
Nanocoatings
d=100 nm
d 100 nm
Example
Nanoparticles
Application
Bottle-neck
Waveguides
Components
for PC, Mobile
phones
x , y
x
Nil
Direction of
confinement
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
8
Unique Properties of Nanomaterials
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
9
Nano-size
Bulk
Properties
Thermal • S / V
• Heat
transport
Small
Electrons
Large
Phonons
Unique properties at the nanoscale have led to the use of nanomaterials in
fields where conventional materials have limitations
Magnetic
Optical
• Super-
paramagnetism
Absent Prominent
• Absorption
• Emission
• Reflection
Bulk effects
Material
dependent
Surface Plasmon
effects
Size dependent
The play of light on a butterfly’s wings has inspired designing of
novel photonic materials for solar cells, photovoltaics,
camouflaging, optical fibers and military applications
Invisibility cloak
Color play
Tailor-making of
refractive index
and dielectric
constant
Nanomaterials : Camouflaging
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
10
Nanomaterials: Photochemical Conversion
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
11
Advantages
➢Utilization of unabsorbed part of solar spectrum
➢Reduced heat dissipation
Quantum Dots
100 nm
50 nm
Reactivity
10 nm
Size (nm)
Nanotubes & nanowires
Mesoporous
Nanomaterials: Self-Cleaning
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
12
Hydrophobic Photocatalytic
Designing of materials with novel effects like hydrophobic,
hydrophilic, photocatalytic, etc. has made
applications like self cleaning, coatings, etc.
possible new
Coating Dirt run-
off
Light
Coating
Roll-off effect
NANOTECHNOLOGY
. METAMATERIALS,
AND THEIR APPLICATIONS
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
13
1
NANOMATERIALS - materials of which a section is between 1 and 100
nanometers long. (a billionth of a meter !)
Materials with structure at the nanoscale often have unique optical,
electronic, thermal (heat), or mechanical properties.
Examples of biological materials that are nanomaterials are:
▪ The overlapping scales on the wing of the Blue Morpho
Butterfly contain nanoscale structures that reflect light to create
iridescent colors.
▪ Chalk
▪ Viruses
▪ Wax crystals covering a lotus leaf
▪ Spider and spider-mite silk
▪ “Spatulae" on the bottom of a Gecko lizard’s feet
▪ Milk and blood
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
14
HOW SMALL IS NANO ?
https://www.youtube.com/watch?v=5AAR7bNSMs go to 55 sec
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
15
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
16
µm = a millionth of a meter nm = a billionth of a meter
.000001 meter .000000001 meter
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
17
2/23/2021 6
A comparison of a
nanotube to the size of a
human hair !!
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
18
SIZE OF THE MARKET FOR NANOMATERIALS
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
19
The global nanomaterials
market size was valued at
8.5 billion in US dollars in
2019.
Aerospace applications are
expected to drive the
market.
Rapid developments in
healthcare technology,
growth in the medical
diagnostics industry, and
various advantages of
medicinal imaging
applications are anticipated.
https://www.youtube.com/watch?reload=9&v=dQhhcgn8YZo
NANO MATERIALS- CLASSIFICATION
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
20
DIFFERENT TYPES OF NANOMATERIALS
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
21
NANOMATERIALS CAN BE DIVIDED INTO 4 TYPES:
1) CARBON-BASED
2) METAL-BASED
3) DENDRIMERS
4) COMPOSITES
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
22
NANOMATERIAL CLASSIFICATION
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
23
Another way to classify
Nanomaterials is based on their
dimensions.
This diagram shows the different
types, depending if they are 0, 1,
2, or 3 dimensional.
CARBON
NANOTUBES (CNT)
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
24
1) CARBON BASED MATERIALS
These nanomaterials are composed
mostly of carbon atoms, most
commonly taking the form of a
hollow spheres, ellipsoids, or
tubes.
Spherical and ellipsoidal
carbon nanomaterials are
referred to as fullerenes,
while cylindrical ones are
called nanotubes.
These particles have many potential
applications, including improved films
and coatings, stronger and lighter
materials, and applications in
electronics.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
25
GRAPHENE – HEXAGON-SHAPED PLANE OF CARBON ATOMS IN SHEET FORM
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
26
11
NANOTUBES ARE FLAT AREAS OF GRAPHENE
THAT IS ROLLED UP INTO A TUBE
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
27
CARBON-BASED
FULLERENES (ALSO CALLED
BUCKYBALLS)
Fullerenes are nanomaterials that are made
of round hollow cages and
have high electrical conductivity and strength.
They are named after Buckminster
Fuller who designed the Geodesic
dome.
The illustration shows some of the well-
known fullerenes consisting of C60
(A) and C70 atoms (B) of carbon.
The number of Carbon atoms can range from
20 to 90.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
28
2) METAL BASED NANOMATERIALS
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
29
These nanomaterials include quantum
dots, nanogold, nanosilver and metal
oxides, such as titanium dioxide.
A quantum dot is a closely packed
semiconductor crystal comprised of
hundreds or thousands of atoms, and
whose size is on the order of a few
nanometers to a few hundred
nanometers.
Changing the size of quantum dots
changes their optical properties.
• Nanoparticles exhibit unique optical properties.
• A change in optical absorption with reduced sizes cause them to glow
when exposed to UV light.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
30
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
31
3) DENDRIMERS
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
32
These nanomaterials are nanosized
polymers built from branched units.
The surface of a dendrimer has numerous
chain ends, which can be tailored to
perform specific chemical functions.
This property could also be useful for
catalysts, to help with chemical reactions.
Also, because three- dimensional
dendrimers contain interior cavities into
which other molecules could be placed,
they may be useful for drug delivery.
4) COMPOSITES
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
33
Composites combine nanoparticles
with other nanoparticles or with
larger
, bulk-type materials.
Clays and Polymers can be used to
make them.
Nanoparticles are already being
added to products ranging from
auto parts to packaging materials,
to enhance the following
properties:
▪ Mechanical
▪ Thermal
▪ Barrier
▪ Flame-retardance
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
34
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
35
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
36
THEY CAN ALSO BE DESCRIBED BY
THEIR DIFFERENT SHAPES
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
37
SCHEMATIC ILLUSTRATION OF DIFFERENT ARCHITECTURES
OF ENGINEERED NANOMATERIALS.
Micelles are a group of molecules in a solution, such as those formed by detergents.
ALiposome is a minute spherical sac of molecules enclosing a water droplet, especially formed
artificially to carry drugs or other substances into the tissues.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
38
NANOWIRES
Background
Nanowires are just like normal
electrical wires other than the fact that
they are extremely small. Like
conventional wires, nanowires can be
made from a variety of conducting and
semiconducting materials like copper,
silver, gold, iron, silicon, zinc
oxide and germanium.
Nanowires can also be made from
carbon nanotubes.
Nanowire Size
Nanowires are less than 100
nanometers in diameter and can be as
small as 3 nanometers. T
ypically
nanowires are more than 1000 times
longer than their diameter
.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
39
Sensor test chips
containing thousands
of nanowires, able to
detect proteins and
other biomarkers left
behind by cancer
cells, could enable
the detection and
diagnosis of cancer in
the early stages from
a few drops of a
patient's blood. Researchers at the Emory/Georgia T
ech Center
of Cancer Nanotechnology Excellence
synthesize, by vapor-solid process, aligned
Zinc Oxide nanowire arrays as shown in the
scanning electron microscopy (SEM) image.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
40
NANORODS
Nanorods are one form of nanoscale objects with
dimensions ranging from 1–100 nm.
A combination of ligands act as shape control agents
and bond to different facets of the nanorod with different
strengths.
This allows different faces of the nanorod to grow at
different rates, producing an elongated object.
USES:
▪ In display technologies, because the reflectivity of
the rods can be changed by changing their
orientation with an applied electric field.
▪ In micro-electro-mechanical systems (MEMS).
▪ In cancer therapeutics.
27
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
41
Carbon Nanotube
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
42
• Carbon nanotubes are allotropes of carbon
with a cylindrical nanostructure.
• They have length-to-diameter ratio of upto
132,000,000:1.
• Nanotubes are members of the fullerene structural family. Their name is
derived from their long, hollow structure with the walls formed by one-atom-
thick sheets of carbon, called graphene.
• Properties
▫ Highest strength to weight ratio, helps
in creating light weight spacecrafts.
▫ Easily penetrate membranes such as
cell walls. Helps in cancer treatment.
▫ Electrical resistance changes significantly when other molecules attach
themselves to the carbon atoms. Helps in developing sensors that can
detect chemical vapours.
Carbon Nanotube
• Application ▫ Easton-Bell Sports, Inc. using
CNT in making bicycle component.
▫ Zyvex Technologies using CNT for
manufacturing of light weight boats.
▫ Replacing transistors from the silicon
chips as they are small and emits less
heat.
▫ In electric cables and wires
▫ In solar cells
▫ In fabrics
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
43
Nanorods(quantum dots)
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
44
• Nanorods are one morphology of
objects.
nanoscale
• Dimensions range from 1–100 nm.
• They may be synthesized from metals or semiconducting
materials.
• A combination of ligands act as shape control agents and
bond to different facets of the nanorod with different
strengths. This allows different faces of the nanorod to grow
at different rates, producing an elongated object.
 USES:
▫ In display technologies, because the reflectivity of the
rods can be changed by changing their orientation with
an applied electric field.
▫ In microelectromechanical systems (MEMS).
▫ In cancer therapeutics.
Nanobots
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
45
• Close to the scale of 10-9.
• Largely in R&d phase .
• Nanobots of 1.5 nanometers across, capable
of counting specific molecules in a chemical sample.
• Since nanorobots would be microscopic in size, it would probably be necessary for very
large numbers of them to work together to perform microscopic and macroscopic tasks.
• Capable of replication using environmental resources .
• Application:
▫ Detection of toxic components in environment.
▫ In drug delivery.
▫ Biomedical instrumention.
Approaches in nanotechnology
1. Bottom up:
In the bottom up approach different
materials
constructed
components
and devices are
from molecular
of their own. They
chemically assemble themselves by
recognizing the molecules of their
own breed.
• Examples of molecular self
assembly are Watson crick base
pairing , nano-lithoghraphy .
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
46
2. Top down:
In top down approach nano objects and materials
are created by larger entities without bouncing
its atomic reactions usually top down approach is
practiced less as compared to the bottom up
approach.
• Solid-state techniques can also be used
• MEMS became practical once they could be fabricated
using modified semiconductor device fabrication
technologies, normally used to make electronics.
to create devices known as
nanoelectromechanical systems or
NEMS, which are related to
microelctromechanical systems or
MEMS.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
47
Materials used
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
48
• Zinc oxide:
▫ Dirt repellent, hydrophobic , cosmetics & stain resistant.
• Silver ion:
▫ Healing property
• Aluminum silicate:
▫ Scratch resistance
• Gold ion:
▫ Chip fabrication, drug delivery.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
49
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
50
Application Of Nanotechnology
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
51
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
52
Application Of Nanotechnology
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
53
Application Of Nanotechnology
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
54
Application Of Nanotechnology
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
55
35
• Materials
• Waterproof and stain-
resistant clothes
• Health Care
• Chemical and biological
sensors, drugs and
delivery devices
POTENTIAL IMPACTS OF NANOTECHNOLOGY
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
56
Thin layers of gold
are used in tiny
medical devices
Carbon nanotubes can
be used for Hydrogen
fuel storage
Possible entry point for
nanomedical device
• Technology
– Better data storage
and computation
• Environment
– Clean energy, clean air
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
57
Nanomaterials in Consumer Products
The Future is Now
2/23/2021 37
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
58
NANOMATERIALS IN CONSUMER PRODUCTS:
THE PERSONAL CARE INDUSTRY IS LEADING
THE WAY
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
59
NANOMATERIALS IN COSMETICS
Shampoos
Conditioners
T
oothpastes
Anti-wrinkle creams
Anti-cellulite creams
Skin moisturizers
Face powders
Aftershave lotions
Deodorants Soaps
Sunscreens
Make up
Perfumes Nail polishes
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology,
DDU Nadiad.
60
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
61
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
62
SUNSCREENS
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
63
Zinc oxide and Titanium dioxide have been used
in sunscreens because of their powerful UV blocking
properties but they leave a white coating on the
skin, which most people find unpleasant.
Many sunscreens and moisturizers available
now use these nanoparticles, including
products from;
 BootAvon
 The Body Shop L'Oreal
 Nivea
 Unilever
THESE
SUNSCREEN
PRODUCTS DO
HAVE NANO
MATERIALS IN
THEM.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
64
MODERN NANOTECHNOLOGY –
ANTIMICROBIAL FABRICS
• Nanohorizons, a company in Pennsylvania,
has started producing a silver nanoparticle
• material as both a dye and
• use in polyester and nylon.
• The silver nanoparticles are toxic to
microbes, and so colonies will never form,
and clothes using this material will not have
odors.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
65
USES FOR CARS
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
66
Nanotechnology in Fabrics
• The properties of familiar materials are
being changed by manufacturers who are
adding nano-sized components to
conventional materials to improve
performance.
▫ For example, some clothing
manufacturers are making water and
stain repellent clothing using nano-
sized whiskers in the fabric that cause
water to bead up on the surface.
▫ In manufacturing bullet proof jackets.
▫ Making spill & dirt resistant,
antimicrobial, antibacterial fabrics.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
67
Some clothing manufacturers are making
water and stain repellent clothing using
nano-sized whiskers in the fabric that
cause water to bead up on the surface.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
68
TITANIUM DIOXIDEPARTICLES IN OUR FOODS
Candies, sweets and chewing gum have been
found to contain the highest levels of titanium
dioxide.
Powdered doughnuts, candies and gums with
hard shells, products with white icing and even
bread, mayonnaise, yogurt and other dairy
products may also contain titanium dioxide.
According to research published in
Environmental Science and Technology, up
to 36 percent of the titanium dioxide found
in nearly 90 food products was in the
nanoparticle sizes.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
69
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
70
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
71
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
72
Candies, sweets and chewing gum have
been found to contain the highest levels
of titanium dioxide.
Powdered doughnuts, candies and gums
with hard shells, products with white
icing and even bread, mayonnaise,
yogurt and other dairy products may also
contain titanium dioxide.
According to research published in
Environmental Science and
Technology, up to 36 percent of the
titanium dioxide found in nearly 90
food products was in the nanoparticle
sizes.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
73
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
74
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
75
GECKO NANOSCALE
FOOT PADS
Animals that cling to walls and walk
on ceilings owe this ability to micro-
and nanoscale hairs on their feet.
The highest adhesion forces are
encountered in lizards called
geckos.
On the sole of a gecko’s toes
there are some one billion tiny
adhesive hairs, about 200
nanometers in both width and
length that have spatula-
shaped ends on them for strong
adhesion to flat surfaces.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
76
GECKO NANO-SCALE FOOT-HAIRS FOR WALKING ANYWHERE
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
77
CC BY-SA 3.0, https://en.wikipedia.org/w/index.php?curid=25482399
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
78
SMART NANOMATERIALS
They are materials which can respond to
Stimuli (forces) from the surrounding
environment.
Stimuli agents are further classified as:
• Light
• T
emperature
• Electricity
• Magnetic
• fields Stress
• Pressure
• pH
• They can be used for controlled release
of drugs, treatment of various diseases,
biosensors, etc.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
79
Nanotechnology in Mobile
• Morph, a nanotechnology concept device
developed by Nokia Research Center (NRC)
and the University of Cambridge (UK).
• The Morph will be super hydrophobic making
it extremely dirt repellent.
• It will be able to charge itself from available light sources
using
photovoltaic nanowire grass covering it's surface.
• Nanoscale electronics also allow stretching. Nokia envisage that
a nanoscale mesh of fibers will allow our mobile devices to be
bent, stretched and folded into any number of conceivable shapes.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
80
Nano Technology in
Energy Sector
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
81
Nanotechnology products in energy
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
82
Nanotechnology products in energy by
application Given the predominance of
photovoltaic products, as expected,
the largest share of products (46%) is
categorized as solar (SO), as seen in
the figure below. Energy storage (ST)
accounts for the second
Nanotechnology in Electronics
• Electrodes made from nanowires
enable flat panel displays to be flexible
as well as thinner than current flat
panel displays.
▫ Nanolithography is used for
fabrication of chips.
glass or thin films of flexible plastic.
▫ E-paper, displays on sunglasses
and
map on car windshields.
▫ The transistors are made of
nanowires, that are assembled on
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
83
Nanotechnology in computers
• The silicon transistors in your computer may be replaced by
transistors based on carbon nanotubes.
• A carbon nanotube is a molecule in form of a hollow cylinder
with a diameter of around a nanometer which consists of
pure carbon.
• Nanorods is a upcoming technology in the displays techniques
due to less consumption of electricity and less heat emission.
• Size of the microprocessors are reduced to greater extend.
• Researchers at North Carolina State University says that growing
arrays of magnetic nanoparticles, called nanodots.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
84
• Hewett Packard is developing a memory device that uses nanowires coated with
titanium dioxide.
• One group of these nanowires is deposited parallel to another group.
• When a perpendicular nanowire is laid over a group of parallel
wires, at each intersection a device called a memristor is formed.
• A memristor can be used as a single-component memory cell in an integrated circuit.
• By reducing the diameter of the nanowires, researchers believe memristor memory
chips can achieve higher memory density than flash memory chips.
• Magnetic nanowires made of an alloy of iron and nickel are being used to create
dense memory devices.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
85
MEDICAL USES OF NANO TECHNOLOGY
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
86
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
87
2/23/2021 62
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
88
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
89
Medical Applications
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
90
•Cancer treatment
•Bone treatment
•Drug delivery
•Appetite control
•Drug development
•Medical tools
•Diagnostic tests
•Imaging
HEALTH CARE
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
91
NERVE TISSUE TALKING TO COMPUTERS
• Neuro-electronic networks interface nerve cells with semiconductors
• Possible applications in brain research, neuro-computation, prosthetics, and
biosensors
Snail neuron grown on a chip that records the neuron’s
electrical activity
Gold tethered to the
67
protein shell of a virus
Health Care: Preventing Viruses from Infecting Us
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
92
• Applying nano-coatings over proteins on viruses
• Could stop viruses from binding to cells
• Never get another cold or flu?
Influenza virus: Note
proteins on outside that
bind to cells
HEALTH CARE: MAKING REPAIRS TO THE BODY
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
93
• Nanorobots are imaginary
, but nano-sized delivery systems could…
• Break apart kidney stones, clear plaque from blood vessels, and
ferry drugs to tumor cells
Nanotechnology in Drugs(Cancer)
• Provide new options for drug delivery and drug therapies.
• Enable drugs to be delivered to precisely the right location
in the body and release drug doses on
a predetermined schedule for optimal treatment.
• Attach the drug to a nanosized carrier.
• They become localized at the disease site, i.e cancer tumour.
• Then they release medicine that kills the tumour.
• Current treatment is through radiotherapy or
chemotherapy.
• Nanobots can clear the blockage in arteries.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
94
COVID-19 DISEASE
MANAGEMENT
Uses include:
▪ Nano-based disinfectants
▪ Personal protective equipment
▪ Diagnostic systems
▪ Treatments and vaccine development
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
95
VARIOUS TYPES OF NANO MEDICINES
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
96
Cancer is a leading cause of
death worldwide.
Currently available therapies
are inadequate and spur
demand for improved
technologies.
Rapid growth in nanotechnology
towards the development of
nanomedicine products holds
great promise to improve
therapeutic strategies against
cancer
.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
97
Theranostic nanoparticles are designed for combining
diagnostic and therapeutic capabilities into one single
biocompatible and biodegradable nanoparticle.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
98
SOME NANOTECHNOLOGY-BASED DRUGS THAT
ARE COMMERCIALLY AVAILABLE OR IN HUMAN
CLINICAL TRIALS
Abraxane, approved by the U.S. Food and Drug
Administration (FDA) is used to treat breast cancer
,
non-small-cell lung cancer
, and pancreatic cancer
.
Doxil was originally approved by the FDA for the use on
HIV-related Kaposi's sarcoma. It is now being used to
also treat ovarian cancer and multiple myeloma.
Onivyde, liposome encapsulated irinotecan to treat
metastatic pancreatic cancer
, was approved by FDA in
October 2015.
Rapamune is a nanocrystal-based drug that was
approved by the FDA in 2000 to prevent organ
rejection after transplantation.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
99
2/23/2021 73
Researchers from North Carolina State
University have developed a wearable,
wireless sensor that can monitor a
person's skin hydration for use in
applications that need to detect
dehydration before it poses a health
problem.
It is made of made of
conductive silver nanowire
inlaid in a silicone matrix.
The device is lightweight, flexible and
stretchable and has already been
incorporated into prototype devices that
can be worn on the wrist or as a chest
patch.
a chest patch. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
100
LAB-ON-SKIN
Stretchable and flexible electronic devices as biosensors for measuring (clockwise from top right)
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
101
skin modulus stiffness)
Electro-cardiology
Hydration
Blood oxygen
Wound-healing rate
Sweat content
Skin surface temperature
Blood pressure,
Electromyography
Electroencephalography. (© ACS)
Nanotechnology materials are going to open
new realms of possibility for flexible and
stretchable monitoring gadgets that are
wearable directly on the skin
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
102
Injected into a healthy mouse,
nanoparticles of cadmium
selenide glow when exposed to
ultra- violet light.
Such quantum dots can seep
into cancerous tumors to help
surgeons find and remove sick
cells without disturbing healthy
ones.
2/23/2021 76
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
103
2/23/2021 77
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
104
2/23/2021 78
Nanoshells
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
105
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
106
They also can be improved diagnostic
tools for cancer and other diseases as
well as low-cost solar energy cells
2/23/2021
81
NANO BORANES FOR CANCER
AND OTHER DISEASE
TREATMENT
Polyhedral Boranes, or clusters of boron
atoms bound to hydrogen atoms, are
transforming the biomedical industry.
These man-made materials have become
the basis for the creation of cancer
therapies, enhanced drug delivery and
new contrast agents needed for radio-
imaging and diagnosis.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
107
NANODENTRISTY
Nanotechnology used in the dental
field is called nanodentistry.
Nanoparticles are used for:
▪ Prevention of oral diseases
▪ Cavity preventive drugs
▪ Prostheses for teeth
implantation
▪ Maintaining oral health
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
108
SAFETY ASPECTS OF
NANOMATERIALS
Nanopollutants could be a risk to the
general population, but especially to
workers in nanotechnology research
and those in manufacturing of buildings.
They are very small nanoparticles
which can let them enter the skin and
be absorbed by the lungs, which can
cause severe health problems.
If the nanopollutants enter the
bloodstream, they may be able to cross
the blood-brain barrier
, therefore
opening up the possibility that these
nanoparticles could severely damage the
brain.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
109
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
110
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
111
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
112
Consumer Products Inventory
An inventory of nanotechnology-based consumer products
introduced on the market.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
113
After more than twenty years of basic and applied research, nanotechnologies
are gaining in commercial use.
But it has been difficult to find out how many “nano” consumer products are on the
market and which merchandise could be called “nano.
”
This inventory gives the public the best available look at the 5,003 !
manufacturer-identified nanotechnology-based consumer products
introduced to the market.
This "living" inventory is a resource for consumers, citizens, policymakers, and others
who are interested in learning about how nanotechnology is entering the
marketplace.
https://www.nanodb.dk/
85
THE END
Nanotechnology in India
• IIT Mumbai is the premier organization in the field of nanotechnology.
• Research in the field of health, environment, medicines are still on.
• Starting in 2001 the Government of India launched the Nano Science and Technology Initiative
(NSTI).
• Then in 2007 the Nanoscience and Technology Mission 2007 was initiated with an allocation of
Rupees 1000 crores for a period of five years.
• The main objectives of the Nano Mission are:
- basic research promotion,
- infrastructure development for carrying out front-ranking research,
- development of nano technologies and their applications,
- human resource development and
- international collaborations.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
114
IIT mumbai project
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
115
https://www.ee.iitb.ac.in/~nanotechnology/
https://www.iitg.ac.in/proj/inup-i2i/iit-bombay.html
Possibilities for the future
• Nanotechnology may make it possible to manufacture lighter, stronger, and
programmable materials that
▫ require less energy to produce than conventional material
▫ and that promise greater fuel efficiency in land transportation, ships, aircraft,
and space vehicles.
• The future of nanotechnology could very well include the use of
nanorobotics.
• These nanorobots have the potential to take on human tasks as well as tasks that
humans could never complete. The rebuilding of the depleted ozone layer could
potentially be able to be performed.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
116
• There would be an entire nano surgical field to help cure everything
from natural aging to diabetes to bone spurs.
• There would be almost nothing that couldn’t be repaired (eventually) with the
introduction of nano surgery.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
117
Pitfalls of nanotechnology
▫ Nano-particles can get into the body through the skin, lungs and digestive system,
thus creating free radicals that can cause cell damage.
▫ Once nano-particles are in the bloodstream, they will be able to cross the blood-brain
barrier.
▫ The most dangerous Nano-application use for military purposes is the Nano-bomb
that contain engineered self multiplying deadly viruses that can continue to wipe out a
community, country or even a civilization.
▫ Nanobots because of their replicating behavior can be big threat for GRAY GOO.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
118
References
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
119
1. http://science.howstuffworks.com/nanotechnology3.htm
2. http://en.wikipedia.org/wiki/Carbon_nanotube
3. http://en.wikipedia.org/wiki/Nanotechnology
4. http://crnano.org/whatis.htm
5. http://www.wifinotes.com/nanotechnology/introduction-to-
nanotechnology.html
6. www.iitb.ac.in/~crnts/
7. www.nafenindia.com/Final_Report_Nano_OK.pd
8. www.sciencedaily.com/releases/2010/05/100531082857.ht m
9. http://www.nanostart.de/index.php/en/nanotechnology/nan
otechnology-information/610-schneller-sparsamer-robuster-
nanotechnologie-in-computer-handy-a-co
10. https://arxiv.org/ftp/arxiv/papers/0801/0801.3280.pdf
Special thanks to HOWIE BAUM – originally compiled by
To see our Research Projects , do visit :-
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
120
• Parmar, S. P., Patel, B. S., Shukla, A., & Dixit, M. (2022). Surfactant Modified Bentonite
Characterization: Effects and Comparative Analysis.
• Pretreatment of biopolymer composite to manufacture sustainable green geotextile: A Review, S. P.
Parmar, Shukla A.D.(2021) Conference Green Technologies for Sustainable Development-
GTSD2021
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
121
Prof. S.P.Parmar - Publications
https://www.slideshare.net/samirsinhparmar/pretreatment-of-biopolymer-composite-ss-606pptx
Disclaimer:
• The presentation published on internet for academic purpose
only.
• Data (in terms of numbers) given may vary, depending on the
experimentation and material variability.
• Figures, websites, references, photos etc. were compiled from
various sources, we respect copyright law, but it is violated in
favor of mankind (students).
• In case of any complaint contact me on given mail ID.
• Jurisdiction is limited to , District court – Godhra.
Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano
Technology, DDU Nadiad.
122
NANO - TECHNOLOGY,MATERIALS & APPLICATIONS.pptx

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NANO - TECHNOLOGY,MATERIALS & APPLICATIONS.pptx

  • 1. NANO: TECHNOLOGY, MATERIALS & APPLICATIONS Introductory Lecture from Shah & Schulman Nano Technology Centre Dharmasinh Desai University, Nadiad Prof. Samirsinh P Parmar under the Guidance of Prof. A.D.Shukla Mail: samirddu@gmail.com Asst. Professor, Department of Civil Engineering, Faculty of Technology, Dharmasinh Desai University, Nadiad-387001 Gujarat, INDIA
  • 2. T opics Covered • Introduction • Definition • History • Timeline • Tools & techniques • ▫ Carbon nanotubes • ▫ Nanorods • ▫ Nanobots • Approaches used • ▫ Top-down • ▫ Bottom-up • Materials used • Application • ▫ Drugs • ▫ Fabrics • ▫ Mobiles • ▫ Electronics • ▫ Computers • ▫ Other uses • Nanotechnology in INDIA • Possibilities for future • Pitfalls of nanotechnology. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 2
  • 3. Defination • Nanotechnology is the study of manipulating matter on an atomic scale. • Nanotechnology refers to the constructing and engineering of the functional systems at very micro level or we can say at atomic level. • A Nanometer is one billionth of a meter, roughly the width of three or four atoms. The average human hair is about 25,000 nanometers wide. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 3
  • 4. Nanomaterials: Materials consisting of particles of the size of nanometer Volume = Surface Area * Thickness ❖ For a given volume: Surface area Thickness ➢More atoms at surface than in the interior ➢Extraordinary activity SCOPE: DEFINITION Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 4
  • 5. Nanomaterials: Features Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 5 ➢Synergistic combinations of materials of different kinds & characteristics is possible through nanotechnology Coatings, Films 10 nm Homogeneous Surface modification Size Reduction 1 m 1 cm + Compatibility Huge interfaces Solid Liquid solution Inorganic nanoparticles in a liquid media
  • 6. Synthesis of Nanomaterials: Ex-situ Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 6 TiO2 TiO2 - - - - - - TiO2 TiO2 - - - - - - 10 nm Polymerization Monomer Monomer Polymer Surfactant - -Radical Polymerization 100 µm Grinding Latex Fe2O3-Particles Fe2O3-Particles Latex bead Pre-treatment Copolymer layer Encapsulated particle Amphiphilic molecule ➢ Ex-situ synthesis of nanomaterials involves number of steps Polymer encapsulated nanomaterials used for targeted delivery of drugs- good example of ex-situ synthesis
  • 7. Synthesis of Nanomaterials : In-situ Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 7 Metal salt + Monomer Adopting in-situ approach of synthesizing nanomaterials reduces number of steps involved and hence simple process ! Nanocomposite 1. Hydrolysis 2. Polymerization
  • 8. 0 - D 1 - D 2 - D Dimension Thermal conductivity is more prominent in 1-D & 2-D nanomaterials Thermal conductivity of C nanotubes (2-D nanomaterial) = 3000 Wm-1K-1; Copper (bulk) = 400 Wm-1K-1 Structure of Nanomaterials: Size and Shape 3 - D Bulk x , y , z Nanocomposite thick film Rods Wires Tubes Nanofilms Nanocoatings d=100 nm d 100 nm Example Nanoparticles Application Bottle-neck Waveguides Components for PC, Mobile phones x , y x Nil Direction of confinement Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 8
  • 9. Unique Properties of Nanomaterials Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 9 Nano-size Bulk Properties Thermal • S / V • Heat transport Small Electrons Large Phonons Unique properties at the nanoscale have led to the use of nanomaterials in fields where conventional materials have limitations Magnetic Optical • Super- paramagnetism Absent Prominent • Absorption • Emission • Reflection Bulk effects Material dependent Surface Plasmon effects Size dependent
  • 10. The play of light on a butterfly’s wings has inspired designing of novel photonic materials for solar cells, photovoltaics, camouflaging, optical fibers and military applications Invisibility cloak Color play Tailor-making of refractive index and dielectric constant Nanomaterials : Camouflaging Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 10
  • 11. Nanomaterials: Photochemical Conversion Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 11 Advantages ➢Utilization of unabsorbed part of solar spectrum ➢Reduced heat dissipation Quantum Dots 100 nm 50 nm Reactivity 10 nm Size (nm) Nanotubes & nanowires Mesoporous
  • 12. Nanomaterials: Self-Cleaning Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 12 Hydrophobic Photocatalytic Designing of materials with novel effects like hydrophobic, hydrophilic, photocatalytic, etc. has made applications like self cleaning, coatings, etc. possible new Coating Dirt run- off Light Coating Roll-off effect
  • 13. NANOTECHNOLOGY . METAMATERIALS, AND THEIR APPLICATIONS Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 13 1
  • 14. NANOMATERIALS - materials of which a section is between 1 and 100 nanometers long. (a billionth of a meter !) Materials with structure at the nanoscale often have unique optical, electronic, thermal (heat), or mechanical properties. Examples of biological materials that are nanomaterials are: ▪ The overlapping scales on the wing of the Blue Morpho Butterfly contain nanoscale structures that reflect light to create iridescent colors. ▪ Chalk ▪ Viruses ▪ Wax crystals covering a lotus leaf ▪ Spider and spider-mite silk ▪ “Spatulae" on the bottom of a Gecko lizard’s feet ▪ Milk and blood Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 14
  • 15. HOW SMALL IS NANO ? https://www.youtube.com/watch?v=5AAR7bNSMs go to 55 sec Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 15
  • 16. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 16
  • 17. µm = a millionth of a meter nm = a billionth of a meter .000001 meter .000000001 meter Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 17
  • 18. 2/23/2021 6 A comparison of a nanotube to the size of a human hair !! Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 18
  • 19. SIZE OF THE MARKET FOR NANOMATERIALS Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 19 The global nanomaterials market size was valued at 8.5 billion in US dollars in 2019. Aerospace applications are expected to drive the market. Rapid developments in healthcare technology, growth in the medical diagnostics industry, and various advantages of medicinal imaging applications are anticipated. https://www.youtube.com/watch?reload=9&v=dQhhcgn8YZo
  • 20. NANO MATERIALS- CLASSIFICATION Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 20
  • 21. DIFFERENT TYPES OF NANOMATERIALS Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 21 NANOMATERIALS CAN BE DIVIDED INTO 4 TYPES: 1) CARBON-BASED 2) METAL-BASED 3) DENDRIMERS 4) COMPOSITES
  • 22. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 22
  • 23. NANOMATERIAL CLASSIFICATION Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 23 Another way to classify Nanomaterials is based on their dimensions. This diagram shows the different types, depending if they are 0, 1, 2, or 3 dimensional. CARBON NANOTUBES (CNT)
  • 24. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 24
  • 25. 1) CARBON BASED MATERIALS These nanomaterials are composed mostly of carbon atoms, most commonly taking the form of a hollow spheres, ellipsoids, or tubes. Spherical and ellipsoidal carbon nanomaterials are referred to as fullerenes, while cylindrical ones are called nanotubes. These particles have many potential applications, including improved films and coatings, stronger and lighter materials, and applications in electronics. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 25
  • 26. GRAPHENE – HEXAGON-SHAPED PLANE OF CARBON ATOMS IN SHEET FORM Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 26
  • 27. 11 NANOTUBES ARE FLAT AREAS OF GRAPHENE THAT IS ROLLED UP INTO A TUBE Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 27
  • 28. CARBON-BASED FULLERENES (ALSO CALLED BUCKYBALLS) Fullerenes are nanomaterials that are made of round hollow cages and have high electrical conductivity and strength. They are named after Buckminster Fuller who designed the Geodesic dome. The illustration shows some of the well- known fullerenes consisting of C60 (A) and C70 atoms (B) of carbon. The number of Carbon atoms can range from 20 to 90. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 28
  • 29. 2) METAL BASED NANOMATERIALS Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 29 These nanomaterials include quantum dots, nanogold, nanosilver and metal oxides, such as titanium dioxide. A quantum dot is a closely packed semiconductor crystal comprised of hundreds or thousands of atoms, and whose size is on the order of a few nanometers to a few hundred nanometers. Changing the size of quantum dots changes their optical properties.
  • 30. • Nanoparticles exhibit unique optical properties. • A change in optical absorption with reduced sizes cause them to glow when exposed to UV light. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 30
  • 31. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 31
  • 32. 3) DENDRIMERS Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 32 These nanomaterials are nanosized polymers built from branched units. The surface of a dendrimer has numerous chain ends, which can be tailored to perform specific chemical functions. This property could also be useful for catalysts, to help with chemical reactions. Also, because three- dimensional dendrimers contain interior cavities into which other molecules could be placed, they may be useful for drug delivery.
  • 33. 4) COMPOSITES Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 33 Composites combine nanoparticles with other nanoparticles or with larger , bulk-type materials. Clays and Polymers can be used to make them. Nanoparticles are already being added to products ranging from auto parts to packaging materials, to enhance the following properties: ▪ Mechanical ▪ Thermal ▪ Barrier ▪ Flame-retardance
  • 34. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 34
  • 35. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 35
  • 36. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 36
  • 37. THEY CAN ALSO BE DESCRIBED BY THEIR DIFFERENT SHAPES Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 37
  • 38. SCHEMATIC ILLUSTRATION OF DIFFERENT ARCHITECTURES OF ENGINEERED NANOMATERIALS. Micelles are a group of molecules in a solution, such as those formed by detergents. ALiposome is a minute spherical sac of molecules enclosing a water droplet, especially formed artificially to carry drugs or other substances into the tissues. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 38
  • 39. NANOWIRES Background Nanowires are just like normal electrical wires other than the fact that they are extremely small. Like conventional wires, nanowires can be made from a variety of conducting and semiconducting materials like copper, silver, gold, iron, silicon, zinc oxide and germanium. Nanowires can also be made from carbon nanotubes. Nanowire Size Nanowires are less than 100 nanometers in diameter and can be as small as 3 nanometers. T ypically nanowires are more than 1000 times longer than their diameter . Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 39
  • 40. Sensor test chips containing thousands of nanowires, able to detect proteins and other biomarkers left behind by cancer cells, could enable the detection and diagnosis of cancer in the early stages from a few drops of a patient's blood. Researchers at the Emory/Georgia T ech Center of Cancer Nanotechnology Excellence synthesize, by vapor-solid process, aligned Zinc Oxide nanowire arrays as shown in the scanning electron microscopy (SEM) image. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 40
  • 41. NANORODS Nanorods are one form of nanoscale objects with dimensions ranging from 1–100 nm. A combination of ligands act as shape control agents and bond to different facets of the nanorod with different strengths. This allows different faces of the nanorod to grow at different rates, producing an elongated object. USES: ▪ In display technologies, because the reflectivity of the rods can be changed by changing their orientation with an applied electric field. ▪ In micro-electro-mechanical systems (MEMS). ▪ In cancer therapeutics. 27 Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 41
  • 42. Carbon Nanotube Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 42 • Carbon nanotubes are allotropes of carbon with a cylindrical nanostructure. • They have length-to-diameter ratio of upto 132,000,000:1. • Nanotubes are members of the fullerene structural family. Their name is derived from their long, hollow structure with the walls formed by one-atom- thick sheets of carbon, called graphene. • Properties ▫ Highest strength to weight ratio, helps in creating light weight spacecrafts. ▫ Easily penetrate membranes such as cell walls. Helps in cancer treatment. ▫ Electrical resistance changes significantly when other molecules attach themselves to the carbon atoms. Helps in developing sensors that can detect chemical vapours.
  • 43. Carbon Nanotube • Application ▫ Easton-Bell Sports, Inc. using CNT in making bicycle component. ▫ Zyvex Technologies using CNT for manufacturing of light weight boats. ▫ Replacing transistors from the silicon chips as they are small and emits less heat. ▫ In electric cables and wires ▫ In solar cells ▫ In fabrics Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 43
  • 44. Nanorods(quantum dots) Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 44 • Nanorods are one morphology of objects. nanoscale • Dimensions range from 1–100 nm. • They may be synthesized from metals or semiconducting materials. • A combination of ligands act as shape control agents and bond to different facets of the nanorod with different strengths. This allows different faces of the nanorod to grow at different rates, producing an elongated object.  USES: ▫ In display technologies, because the reflectivity of the rods can be changed by changing their orientation with an applied electric field. ▫ In microelectromechanical systems (MEMS). ▫ In cancer therapeutics.
  • 45. Nanobots Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 45 • Close to the scale of 10-9. • Largely in R&d phase . • Nanobots of 1.5 nanometers across, capable of counting specific molecules in a chemical sample. • Since nanorobots would be microscopic in size, it would probably be necessary for very large numbers of them to work together to perform microscopic and macroscopic tasks. • Capable of replication using environmental resources . • Application: ▫ Detection of toxic components in environment. ▫ In drug delivery. ▫ Biomedical instrumention.
  • 46. Approaches in nanotechnology 1. Bottom up: In the bottom up approach different materials constructed components and devices are from molecular of their own. They chemically assemble themselves by recognizing the molecules of their own breed. • Examples of molecular self assembly are Watson crick base pairing , nano-lithoghraphy . Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 46
  • 47. 2. Top down: In top down approach nano objects and materials are created by larger entities without bouncing its atomic reactions usually top down approach is practiced less as compared to the bottom up approach. • Solid-state techniques can also be used • MEMS became practical once they could be fabricated using modified semiconductor device fabrication technologies, normally used to make electronics. to create devices known as nanoelectromechanical systems or NEMS, which are related to microelctromechanical systems or MEMS. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 47
  • 48. Materials used Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 48 • Zinc oxide: ▫ Dirt repellent, hydrophobic , cosmetics & stain resistant. • Silver ion: ▫ Healing property • Aluminum silicate: ▫ Scratch resistance • Gold ion: ▫ Chip fabrication, drug delivery.
  • 49. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 49
  • 50. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 50
  • 51. Application Of Nanotechnology Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 51
  • 52. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 52 Application Of Nanotechnology
  • 53. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 53 Application Of Nanotechnology
  • 54. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 54 Application Of Nanotechnology
  • 55. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 55
  • 56. 35 • Materials • Waterproof and stain- resistant clothes • Health Care • Chemical and biological sensors, drugs and delivery devices POTENTIAL IMPACTS OF NANOTECHNOLOGY Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 56 Thin layers of gold are used in tiny medical devices Carbon nanotubes can be used for Hydrogen fuel storage Possible entry point for nanomedical device • Technology – Better data storage and computation • Environment – Clean energy, clean air
  • 57. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 57
  • 58. Nanomaterials in Consumer Products The Future is Now 2/23/2021 37 Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 58
  • 59. NANOMATERIALS IN CONSUMER PRODUCTS: THE PERSONAL CARE INDUSTRY IS LEADING THE WAY Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 59
  • 60. NANOMATERIALS IN COSMETICS Shampoos Conditioners T oothpastes Anti-wrinkle creams Anti-cellulite creams Skin moisturizers Face powders Aftershave lotions Deodorants Soaps Sunscreens Make up Perfumes Nail polishes Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 60
  • 61. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 61
  • 62. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 62
  • 63. SUNSCREENS Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 63 Zinc oxide and Titanium dioxide have been used in sunscreens because of their powerful UV blocking properties but they leave a white coating on the skin, which most people find unpleasant. Many sunscreens and moisturizers available now use these nanoparticles, including products from;  BootAvon  The Body Shop L'Oreal  Nivea  Unilever
  • 64. THESE SUNSCREEN PRODUCTS DO HAVE NANO MATERIALS IN THEM. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 64
  • 65. MODERN NANOTECHNOLOGY – ANTIMICROBIAL FABRICS • Nanohorizons, a company in Pennsylvania, has started producing a silver nanoparticle • material as both a dye and • use in polyester and nylon. • The silver nanoparticles are toxic to microbes, and so colonies will never form, and clothes using this material will not have odors. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 65
  • 66. USES FOR CARS Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 66
  • 67. Nanotechnology in Fabrics • The properties of familiar materials are being changed by manufacturers who are adding nano-sized components to conventional materials to improve performance. ▫ For example, some clothing manufacturers are making water and stain repellent clothing using nano- sized whiskers in the fabric that cause water to bead up on the surface. ▫ In manufacturing bullet proof jackets. ▫ Making spill & dirt resistant, antimicrobial, antibacterial fabrics. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 67
  • 68. Some clothing manufacturers are making water and stain repellent clothing using nano-sized whiskers in the fabric that cause water to bead up on the surface. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 68
  • 69. TITANIUM DIOXIDEPARTICLES IN OUR FOODS Candies, sweets and chewing gum have been found to contain the highest levels of titanium dioxide. Powdered doughnuts, candies and gums with hard shells, products with white icing and even bread, mayonnaise, yogurt and other dairy products may also contain titanium dioxide. According to research published in Environmental Science and Technology, up to 36 percent of the titanium dioxide found in nearly 90 food products was in the nanoparticle sizes. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 69
  • 70. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 70
  • 71. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 71
  • 72. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 72
  • 73. Candies, sweets and chewing gum have been found to contain the highest levels of titanium dioxide. Powdered doughnuts, candies and gums with hard shells, products with white icing and even bread, mayonnaise, yogurt and other dairy products may also contain titanium dioxide. According to research published in Environmental Science and Technology, up to 36 percent of the titanium dioxide found in nearly 90 food products was in the nanoparticle sizes. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 73
  • 74. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 74
  • 75. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 75
  • 76. GECKO NANOSCALE FOOT PADS Animals that cling to walls and walk on ceilings owe this ability to micro- and nanoscale hairs on their feet. The highest adhesion forces are encountered in lizards called geckos. On the sole of a gecko’s toes there are some one billion tiny adhesive hairs, about 200 nanometers in both width and length that have spatula- shaped ends on them for strong adhesion to flat surfaces. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 76
  • 77. GECKO NANO-SCALE FOOT-HAIRS FOR WALKING ANYWHERE Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 77 CC BY-SA 3.0, https://en.wikipedia.org/w/index.php?curid=25482399
  • 78. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 78
  • 79. SMART NANOMATERIALS They are materials which can respond to Stimuli (forces) from the surrounding environment. Stimuli agents are further classified as: • Light • T emperature • Electricity • Magnetic • fields Stress • Pressure • pH • They can be used for controlled release of drugs, treatment of various diseases, biosensors, etc. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 79
  • 80. Nanotechnology in Mobile • Morph, a nanotechnology concept device developed by Nokia Research Center (NRC) and the University of Cambridge (UK). • The Morph will be super hydrophobic making it extremely dirt repellent. • It will be able to charge itself from available light sources using photovoltaic nanowire grass covering it's surface. • Nanoscale electronics also allow stretching. Nokia envisage that a nanoscale mesh of fibers will allow our mobile devices to be bent, stretched and folded into any number of conceivable shapes. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 80
  • 81. Nano Technology in Energy Sector Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 81
  • 82. Nanotechnology products in energy Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 82 Nanotechnology products in energy by application Given the predominance of photovoltaic products, as expected, the largest share of products (46%) is categorized as solar (SO), as seen in the figure below. Energy storage (ST) accounts for the second
  • 83. Nanotechnology in Electronics • Electrodes made from nanowires enable flat panel displays to be flexible as well as thinner than current flat panel displays. ▫ Nanolithography is used for fabrication of chips. glass or thin films of flexible plastic. ▫ E-paper, displays on sunglasses and map on car windshields. ▫ The transistors are made of nanowires, that are assembled on Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 83
  • 84. Nanotechnology in computers • The silicon transistors in your computer may be replaced by transistors based on carbon nanotubes. • A carbon nanotube is a molecule in form of a hollow cylinder with a diameter of around a nanometer which consists of pure carbon. • Nanorods is a upcoming technology in the displays techniques due to less consumption of electricity and less heat emission. • Size of the microprocessors are reduced to greater extend. • Researchers at North Carolina State University says that growing arrays of magnetic nanoparticles, called nanodots. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 84
  • 85. • Hewett Packard is developing a memory device that uses nanowires coated with titanium dioxide. • One group of these nanowires is deposited parallel to another group. • When a perpendicular nanowire is laid over a group of parallel wires, at each intersection a device called a memristor is formed. • A memristor can be used as a single-component memory cell in an integrated circuit. • By reducing the diameter of the nanowires, researchers believe memristor memory chips can achieve higher memory density than flash memory chips. • Magnetic nanowires made of an alloy of iron and nickel are being used to create dense memory devices. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 85
  • 86. MEDICAL USES OF NANO TECHNOLOGY Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 86
  • 87. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 87
  • 88. 2/23/2021 62 Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 88
  • 89. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 89
  • 90. Medical Applications Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 90 •Cancer treatment •Bone treatment •Drug delivery •Appetite control •Drug development •Medical tools •Diagnostic tests •Imaging
  • 91. HEALTH CARE Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 91 NERVE TISSUE TALKING TO COMPUTERS • Neuro-electronic networks interface nerve cells with semiconductors • Possible applications in brain research, neuro-computation, prosthetics, and biosensors Snail neuron grown on a chip that records the neuron’s electrical activity
  • 92. Gold tethered to the 67 protein shell of a virus Health Care: Preventing Viruses from Infecting Us Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 92 • Applying nano-coatings over proteins on viruses • Could stop viruses from binding to cells • Never get another cold or flu? Influenza virus: Note proteins on outside that bind to cells
  • 93. HEALTH CARE: MAKING REPAIRS TO THE BODY Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 93 • Nanorobots are imaginary , but nano-sized delivery systems could… • Break apart kidney stones, clear plaque from blood vessels, and ferry drugs to tumor cells
  • 94. Nanotechnology in Drugs(Cancer) • Provide new options for drug delivery and drug therapies. • Enable drugs to be delivered to precisely the right location in the body and release drug doses on a predetermined schedule for optimal treatment. • Attach the drug to a nanosized carrier. • They become localized at the disease site, i.e cancer tumour. • Then they release medicine that kills the tumour. • Current treatment is through radiotherapy or chemotherapy. • Nanobots can clear the blockage in arteries. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 94
  • 95. COVID-19 DISEASE MANAGEMENT Uses include: ▪ Nano-based disinfectants ▪ Personal protective equipment ▪ Diagnostic systems ▪ Treatments and vaccine development Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 95
  • 96. VARIOUS TYPES OF NANO MEDICINES Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 96
  • 97. Cancer is a leading cause of death worldwide. Currently available therapies are inadequate and spur demand for improved technologies. Rapid growth in nanotechnology towards the development of nanomedicine products holds great promise to improve therapeutic strategies against cancer . Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 97
  • 98. Theranostic nanoparticles are designed for combining diagnostic and therapeutic capabilities into one single biocompatible and biodegradable nanoparticle. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 98
  • 99. SOME NANOTECHNOLOGY-BASED DRUGS THAT ARE COMMERCIALLY AVAILABLE OR IN HUMAN CLINICAL TRIALS Abraxane, approved by the U.S. Food and Drug Administration (FDA) is used to treat breast cancer , non-small-cell lung cancer , and pancreatic cancer . Doxil was originally approved by the FDA for the use on HIV-related Kaposi's sarcoma. It is now being used to also treat ovarian cancer and multiple myeloma. Onivyde, liposome encapsulated irinotecan to treat metastatic pancreatic cancer , was approved by FDA in October 2015. Rapamune is a nanocrystal-based drug that was approved by the FDA in 2000 to prevent organ rejection after transplantation. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 99
  • 100. 2/23/2021 73 Researchers from North Carolina State University have developed a wearable, wireless sensor that can monitor a person's skin hydration for use in applications that need to detect dehydration before it poses a health problem. It is made of made of conductive silver nanowire inlaid in a silicone matrix. The device is lightweight, flexible and stretchable and has already been incorporated into prototype devices that can be worn on the wrist or as a chest patch. a chest patch. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 100
  • 101. LAB-ON-SKIN Stretchable and flexible electronic devices as biosensors for measuring (clockwise from top right) Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 101 skin modulus stiffness) Electro-cardiology Hydration Blood oxygen Wound-healing rate Sweat content Skin surface temperature Blood pressure, Electromyography Electroencephalography. (© ACS) Nanotechnology materials are going to open new realms of possibility for flexible and stretchable monitoring gadgets that are wearable directly on the skin
  • 102. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 102
  • 103. Injected into a healthy mouse, nanoparticles of cadmium selenide glow when exposed to ultra- violet light. Such quantum dots can seep into cancerous tumors to help surgeons find and remove sick cells without disturbing healthy ones. 2/23/2021 76 Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 103
  • 104. 2/23/2021 77 Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 104
  • 105. 2/23/2021 78 Nanoshells Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 105
  • 106. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 106
  • 107. They also can be improved diagnostic tools for cancer and other diseases as well as low-cost solar energy cells 2/23/2021 81 NANO BORANES FOR CANCER AND OTHER DISEASE TREATMENT Polyhedral Boranes, or clusters of boron atoms bound to hydrogen atoms, are transforming the biomedical industry. These man-made materials have become the basis for the creation of cancer therapies, enhanced drug delivery and new contrast agents needed for radio- imaging and diagnosis. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 107
  • 108. NANODENTRISTY Nanotechnology used in the dental field is called nanodentistry. Nanoparticles are used for: ▪ Prevention of oral diseases ▪ Cavity preventive drugs ▪ Prostheses for teeth implantation ▪ Maintaining oral health Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 108
  • 109. SAFETY ASPECTS OF NANOMATERIALS Nanopollutants could be a risk to the general population, but especially to workers in nanotechnology research and those in manufacturing of buildings. They are very small nanoparticles which can let them enter the skin and be absorbed by the lungs, which can cause severe health problems. If the nanopollutants enter the bloodstream, they may be able to cross the blood-brain barrier , therefore opening up the possibility that these nanoparticles could severely damage the brain. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 109
  • 110. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 110
  • 111. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 111
  • 112. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 112
  • 113. Consumer Products Inventory An inventory of nanotechnology-based consumer products introduced on the market. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 113 After more than twenty years of basic and applied research, nanotechnologies are gaining in commercial use. But it has been difficult to find out how many “nano” consumer products are on the market and which merchandise could be called “nano. ” This inventory gives the public the best available look at the 5,003 ! manufacturer-identified nanotechnology-based consumer products introduced to the market. This "living" inventory is a resource for consumers, citizens, policymakers, and others who are interested in learning about how nanotechnology is entering the marketplace. https://www.nanodb.dk/ 85 THE END
  • 114. Nanotechnology in India • IIT Mumbai is the premier organization in the field of nanotechnology. • Research in the field of health, environment, medicines are still on. • Starting in 2001 the Government of India launched the Nano Science and Technology Initiative (NSTI). • Then in 2007 the Nanoscience and Technology Mission 2007 was initiated with an allocation of Rupees 1000 crores for a period of five years. • The main objectives of the Nano Mission are: - basic research promotion, - infrastructure development for carrying out front-ranking research, - development of nano technologies and their applications, - human resource development and - international collaborations. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 114
  • 115. IIT mumbai project Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 115 https://www.ee.iitb.ac.in/~nanotechnology/ https://www.iitg.ac.in/proj/inup-i2i/iit-bombay.html
  • 116. Possibilities for the future • Nanotechnology may make it possible to manufacture lighter, stronger, and programmable materials that ▫ require less energy to produce than conventional material ▫ and that promise greater fuel efficiency in land transportation, ships, aircraft, and space vehicles. • The future of nanotechnology could very well include the use of nanorobotics. • These nanorobots have the potential to take on human tasks as well as tasks that humans could never complete. The rebuilding of the depleted ozone layer could potentially be able to be performed. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 116
  • 117. • There would be an entire nano surgical field to help cure everything from natural aging to diabetes to bone spurs. • There would be almost nothing that couldn’t be repaired (eventually) with the introduction of nano surgery. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 117
  • 118. Pitfalls of nanotechnology ▫ Nano-particles can get into the body through the skin, lungs and digestive system, thus creating free radicals that can cause cell damage. ▫ Once nano-particles are in the bloodstream, they will be able to cross the blood-brain barrier. ▫ The most dangerous Nano-application use for military purposes is the Nano-bomb that contain engineered self multiplying deadly viruses that can continue to wipe out a community, country or even a civilization. ▫ Nanobots because of their replicating behavior can be big threat for GRAY GOO. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 118
  • 119. References Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 119 1. http://science.howstuffworks.com/nanotechnology3.htm 2. http://en.wikipedia.org/wiki/Carbon_nanotube 3. http://en.wikipedia.org/wiki/Nanotechnology 4. http://crnano.org/whatis.htm 5. http://www.wifinotes.com/nanotechnology/introduction-to- nanotechnology.html 6. www.iitb.ac.in/~crnts/ 7. www.nafenindia.com/Final_Report_Nano_OK.pd 8. www.sciencedaily.com/releases/2010/05/100531082857.ht m 9. http://www.nanostart.de/index.php/en/nanotechnology/nan otechnology-information/610-schneller-sparsamer-robuster- nanotechnologie-in-computer-handy-a-co 10. https://arxiv.org/ftp/arxiv/papers/0801/0801.3280.pdf Special thanks to HOWIE BAUM – originally compiled by
  • 120. To see our Research Projects , do visit :- Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 120
  • 121. • Parmar, S. P., Patel, B. S., Shukla, A., & Dixit, M. (2022). Surfactant Modified Bentonite Characterization: Effects and Comparative Analysis. • Pretreatment of biopolymer composite to manufacture sustainable green geotextile: A Review, S. P. Parmar, Shukla A.D.(2021) Conference Green Technologies for Sustainable Development- GTSD2021 Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 121 Prof. S.P.Parmar - Publications https://www.slideshare.net/samirsinhparmar/pretreatment-of-biopolymer-composite-ss-606pptx
  • 122. Disclaimer: • The presentation published on internet for academic purpose only. • Data (in terms of numbers) given may vary, depending on the experimentation and material variability. • Figures, websites, references, photos etc. were compiled from various sources, we respect copyright law, but it is violated in favor of mankind (students). • In case of any complaint contact me on given mail ID. • Jurisdiction is limited to , District court – Godhra. Prof. S.P.Parmar, & Shukla A.K.- Centre of Nano Technology, DDU Nadiad. 122