1. DNA is often
called the
blueprint of life.
In simple terms,
DNA contains the
instructions for
making proteins
within the cell.
2. We study DNA forWe study DNA for
many reasons:many reasons:
its centralits central
importance to allimportance to all
life on Earthlife on Earth
medical benefitsmedical benefits
such as cures forsuch as cures for
diseasesdiseases
better foodbetter food
crops.crops.
3. ChromosomesChromosomes
are made up ofare made up of
genes.genes.
Genes areGenes are
made up of amade up of a
chemical calledchemical called
DNA.DNA.
4. DNA is a veryDNA is a very
long molecule.long molecule.
The basic shapeThe basic shape
is like a twistedis like a twisted
ladder or zipper.ladder or zipper.
This is called aThis is called a
double helix.double helix.
5. The backbone ofThe backbone of
the molecule isthe molecule is
alternatingalternating
phosphatephosphate andand
deoxyribosedeoxyribose, a, a
sugar, parts.sugar, parts.
The teeth areThe teeth are
nitrogenousnitrogenous
basesbases..
phosphate
deoxyribose
bases
6. The DNA doubleThe DNA double
helix has twohelix has two
strands twistedstrands twisted
together.together.
(In the rest of(In the rest of
this unit we willthis unit we will
look at thelook at the
structure of onestructure of one
strand.)strand.)
11. Each side of the
ladder is made up
of nucleic acids.
The backbone is a
phosphate and a
sugar
The rung of the
ladder is the
nitrogen base.
12. When makingWhen making
hydrogen bonds,hydrogen bonds,
cytosine alwayscytosine always
pairs up withpairs up with
guanine,guanine,
And adenineAnd adenine
always pairs upalways pairs up
with thymine.with thymine.
(Adenine and(Adenine and
thymine arethymine are
shown here.)shown here.)
C
C
C
C
N
N
N
N
N
C
C
C
C
C
N
N
OO
OO
C
13. CytosineCytosine CC
ThymineThymine TT
AdenineAdenine AA
GuanineGuanine GG
DNA has four different bases:DNA has four different bases:
14. Remember, DNARemember, DNA
has two strandshas two strands
that fit togetherthat fit together
something like asomething like a
zipper.zipper.
The teeth are theThe teeth are the
nitrogenousnitrogenous
bases but why dobases but why do
they stickthey stick
together?together?
17. Where is DNA
located?
What does it look
like?
What are its bases?
What is bound
between of bases
and bound between
of nucleotide?
Editor's Notes
Why is DNA called the blueprint of life?
About better food crops, this area is controversial. There is a Dr. Charles Arntzen who is working on bioengineering foods with vaccines in them. People in poor countries could be immunized against diseases just by eating a banana, for instance.
{Ask students where the chromosomes are in this picture. Or ask them where the DNA is. Remind them that the mitochondria also have DNA.}
{Show students a model of the double helix. Explain what a spiral is and a helix is.}
{Point to the 3-D mode, if you have one, to show the parts as you discuss them.}
We will take apart the DNA molecule to see how it is put together.
First, we will look at one strand.
{Ask students where they have seen a similar molecule before in this class.
Answer: ATP . Emphasize that nucleotides are the basic building blocks or units of a DNA molecule and that a single molecule has many millions of nucleotides.}
These four bases are abbreviated by using their respective first letters.
{Point to the 3-D model to show the parts as you discuss them.}