This document provides guidance on writing a manuscript. It discusses the key components and structure, including an introduction, methodology, results, discussion, acknowledgments and references. The methodology section should provide enough detail that other researchers could reproduce the study. Results should describe findings from data, tables and figures. The discussion section should interpret the findings, compare to prior literature, and discuss implications. References should be in the style specified by the target journal. Overall, the manuscript should tell a clear and cohesive story to communicate the science to readers.

1. How to write a Manuscript:
Components and Structure of
Manuscript writing
An Academic presentation by
Dr. Nancy Agnes, Head, Technical Operations, Pubrica
Group: www.pubrica.com
Email: sales@pubrica.com

2. Make sure your message is clear
Components and structure of Manuscript Writing
Methodology
Methodology sub-sections for Research paper writing
Result
Discussion
Acknowledgement
References
About Pubrica
Outline
TODAY'S DISCUSSION

3. Contd...
The goal of manuscript writing is to go
beyond simply presenting facts and ideas.
It is to reach out to the reader to successfully
explain your findings and assist readers in
comprehending the topics at hand..
INTRODUCTION

4. This blog introduces and shows several
techniques for arranging a manuscript so that
readers remember the most important
messages you want to communicate after
reading it.
Although manuscript writing has a strict
format, there is still room to weave a
captivating story that communicates the
science while still being enjoyable. Scientists,
authors, and editors discuss the value and
significance of creativity and how to create a
great study.

5. Consider the message you wish to send to
your readers. If that isn't clear, there may be
later misinterpretations.
When a multidisciplinary group of authors is
becoming more common, a clear message is
even more crucial.
Make sure your message is clear
Contd...

6. I encourage groups to meet in person and
seek consensus on the main message and
the data selection, visual presentation, and
information needed to convey a powerful
message.
The main text should contain the most crucial
information, and additional data should be
placed in the supplementary content to avoid
distraction.
Contd...

7. Countless manuscripts are turned down
because the discussion part is so lacking that
it's plain the author doesn't understand the
existing literature.
Writers should place their findings in a larger
context to show what makes them valuable or
unique.
Contd...

8. There is a fine line between hypothesis and
evidence-based judgments to be drawn. In
the conversation, a writer can conjecture but
not excessively.
It's never good when the conversation is just
guesswork because it's not based on the
author's experience. Include a one- or two-
sentence statement in the end on the study
you want to conduct in the future and what
else needs to be investigated.

9. Components and structure
of Manuscript Writing
After the title and abstract, the first part of a
research paper is the abstract. It is usually
short and communicates the scope of the
research paper writing (the rationale and goal
of the investigation).
It should include the study's background (the
existing body of knowledge), significance,
and objectives. It should explicitly explain or
describe the research questions/hypotheses
being tested.

11. METHODOLOGY
The approach used determines whether or
not a study is valid. The Methodology
section should be given in such detail and
clarity that other researchers can reproduce
the work in their own environment.
The section on methodology is divided into
two parts: "Materials" and "Methods."
Contd...

12. Who/what was studied (e.g., humans, animals, corpses, tissue preparations)?
Who/what was inspected (e.g., humans, animals, corpses, tissue preparations)?
What types of therapies were used (for example, oral, injectable, and gas)?
What tools were employed in the investigation (e.g., HPLC, haemoglobin meters)?

13. The "Methods" section explains how
individuals were manipulated to answer the
experimental question, how measurements
and computations were performed, and how
data was stored and analyzed."

14. METHODOLOGY SUB-SECTIONS
FOR RESEARCH PAPER WRITING
The ethical criteria established by the country
or region should be mentioned and followed
in the Methods section.
The ICMR's Ethical Guidelines for Biomedical
Research on Human Participants, for
example, are a valuable resource for
reference while researching human subjects
in India.
Contd...

15. The ICMR's Guidelines for the use of Animals
in Scientific Research/INSA's Guidelines for
Care and Use of Animals in Scientific
Research.
The Committee for Control and Supervision
of Experiments on Animals (CPCSEA
Guidelines) for Care and Use of Animals in
Scientific Research (CPCSEA Guidelines) for
Care and Use of Animals in Scientific
Research (INSR).
Contd...

16. The Methodology sections of manuscript
writing are the final subcomponent deals with
data management and statistical analysis.
In the publication, it is critical to state how
data quality was ensured throughout the
investigation, including whether a single or
double data entry approach was utilized for
data management.
Contd...

17. As part of the data management technique,
the authors should specify whether
consistency or random checks were
performed. It's critical to include the name of
the statistical programme used for data entry
and analysis, along with the required
references.
The Methodology part should always be
written in the past tense and presented
logically and ordered.

18. Contd...
RESULT
The easiest section to write is the Results
section for manuscript writing. In this section,
one must describe the intervention/findings.
Observation’s Text, Tables, and Graphs are
the most common components of the Results
section.

19. So that unnecessary duplication of material
supplied in tables and figures is avoided in
the text.
The text should deliver unique information
and highlight the most significant features of
the figures and tables. Only the most critical
points should be underlined or summarized. It
is not necessary to display the same data in
tables and figures.

20. One of the most challenging portions of a manuscript
to write is the Discussion section. The commentary
adds value to the paper by comparing the authors'
work to that of other scientists.
The discussion should be on the interpretation
(findings), and the debate should focus on how the
study results contribute to the overall picture.
DISCUSSION
Contd...

21. Current manuscript writing, explain the
findings and compare the study's
conclusions.
Discuss the limits and, if possible, the
implications for future research after
comparing your results to other literature. A
summary is usually given at the end of the
conversation.

22. ACKNOWLEDGEMENT
It's important to recognize people who don't
fit the authorship standards, and the
acknowledgement should be brief and limited
to particular scientific or technical aid and
financial support.
Individuals who provide standard
departmental services and help produce
manuscript writing without actually
contributing to scientific content are not
needed to be acknowledged.

23. The manuscript's writing type and nature
determine the overall number of references.
It's always a moral idea to check the
"Instructions to the Authors" page for specific
instructions.
Citations should be numbered in the same
order as they appear in the text and placed
after the document. The referencing style
varies on the magazine, so careful
consideration should be given before journal
publication.
REFERENCES

24. Pubrica's manuscript writing service has
worked with several medical and scientific
journals.
The Pubrica Researcher Team creates a
solid review that can be a valuable tool for
practitioners, offering a concise synthesis and
analysis of the relevant information in a
specific field.
ABOUT PUBRICA

25. REFERENCES
Virginia Gewin How to write a first-class
paper; nature 16 March 2018.
Sitanshu Sekhar Kar, Rakhee Kar
Components and Structure of a Manuscript,
Writing and Publishing a Scientific Research
Paper pp 9-15.

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