3. OBJECTIVES
• To review brief anatomy of meninges
• To introduce and define the topic
• To state the incidence of meningitis
• To enlist the etiology
• To explain clinical manifestation and
pathophysiology
• To enumerate diagnostic evaluation
4.
5.
6. Terms / Values to Remember
• Leptomeninges
• Normal ICP
• Normal production of CSF / day
• Normal CSF contents
• BBB
7. DEFINITION
• Meningitis is a inflammation of the meninges,
the three layers of membranes that enclose the
brain and spinal cord.
8. INCIDENCE
• With almost 4100 cases and 500 deaths
occurring annually in India, bacterial
meningitis continues to be a significant source
of morbidity and mortality; the annual
incidence in the India is 1.33 cases per 100,000
population.
- 2020 WHO census
9. CAUSES
• Bacteria. S. Pneumonai, is the most common
bacterial cause of meningitis.
• Viruses – HSV, Entero Virus
• Fungi
• Parasites
• Others