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Benign prostatic hypertrophy
Azm-e-Guda-e Mazi
Dr. MSM Shiffa
MD, BUMS, LLB, AAL
Definition
• Benign prostatic hypertrophy (BPH) is a
condition of unknown aetiology characterized
by an increase in size of the inner zone
(periurethral glands) of the prostate gland
Epidemiology
• Present in 50% of 60–90-year-old-men
Pathophysiology
• Microscopic stromal nodules develop around
the periurethral glands
• Glandular hyperplasia originates around these
nodules
• As the gland increases in size, it compresses
the urethra, leading to urinary tract
obstruction
Asbab
• Kasarat-e-mubasharat
• Excessive use of Sharab
• Effect of sardi and garmi
• Sitting on a hard surface for a long time
Aqsam
• Narm – soft
• Sakht - hard
Clinical features
Initially outlet obstruction:
• Weak stream, hesitancy, intermittency, dribbling,
straining to void, acute urinary retention
Subsequent detrusor instability:
• Frequency, urgency, nocturia, dysuria, urge
incontinence
Finally detrusor failure and chronic retention:
• Palpable (or percussible) bladder, overflow
incontinence
• Enlarged smooth prostate on digital rectal
examination
• Narrowing of urethra
• Hesitancy at the beginning
• Desire to urinate but unable to do so
• Dysuria
• Salasul bole (incontinence)
• Bole ud dam
• Ihtibas e bol
• Bad odour of urine
• Sleep disturbance
Investigations
• Basic investigations
• Urinalysis and urine culture for evidence of
infection or haematuria.
• FBC: infection.
• U+E and serum creatinine: renal function.
• PSA: suspicion of underlying malignancy.
Further investigations
• Voiding diary.
• Uroflowmetry and residual volume
measurement (normal <100 ml): evidence of
obstruction.
• Ultrasonography of kidneys and bladder:
structural abnormalities.
• Transrectal ultrasound: to determine prostate
size.
• IVU: structural abnormalities.
• Cystoscopy.
Complications (of surgical treatment)
• Postoperative haemorrhage and clot retention.
• UTI.
• Retrograde ejaculation, impotence.
• TURP syndrome: in 2% of patients absorption of
irrigation fluid via venous sinuses in the prostate
causes hyponatraemia, hypotension and
metabolic acidosis.
• Incontinence.
• Urethral stricture.
ESSENTIAL MANAGEMENT
Medical
• Alter oral fluid intake, reduce caffeine intake.
• α-Adrenergic blockers (e.g. phenoxybenzamine,
prazosin).
• Anti-androgens acting selectively at prostatic
cellular level (e.g. finasteride).
• Intermittent self-catheterization if detrusor
failure.
• Balloon dilatation and stenting of prostate (unfit
patient).
Surgical
• Majority of patients are treated surgically.
• Surgical removal of the adenomatous portion
of the prostate.
• TURP with electrocautery or laser.
• Thermal ablation of prostate.
• Open prostatectomy if large which may be
transvesical or retropubic.
Usool-e-ilaj
• Eliminate the cause
• Stop alcohol
• Reduce the kasarat e mubasharat
• Avoid extreme hotn and cold
• Mudir-e-bole
• Daf-e-tasannuj
• Muhallil
• Daf-e-tafoon
• Abzan
• Dalak
• Qabizat (cautious)
Ilaj
• Balooti 5 g with milk or water
• Jawarish-e-zarooni 5 -10 g
• Majoone dabeedul ward 5 g along 60 ml of
arq-e-mako
• Majoon-e-masikul bole
• Lunuwarana pothu kasaya 12 kalang
• Chandrabrabawati - P2 m & e
• Thripala choorna - 1 tsp m & e
• Vasti
– Narayana thaila : Dashamula kasaya = 1:5 or
Narayana alone
• Apply Dasanga lepa + siyambala kola
Thank you

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Prostatic enlargement

  • 1. Benign prostatic hypertrophy Azm-e-Guda-e Mazi Dr. MSM Shiffa MD, BUMS, LLB, AAL
  • 2. Definition • Benign prostatic hypertrophy (BPH) is a condition of unknown aetiology characterized by an increase in size of the inner zone (periurethral glands) of the prostate gland Epidemiology • Present in 50% of 60–90-year-old-men
  • 3. Pathophysiology • Microscopic stromal nodules develop around the periurethral glands • Glandular hyperplasia originates around these nodules • As the gland increases in size, it compresses the urethra, leading to urinary tract obstruction
  • 4. Asbab • Kasarat-e-mubasharat • Excessive use of Sharab • Effect of sardi and garmi • Sitting on a hard surface for a long time
  • 5. Aqsam • Narm – soft • Sakht - hard
  • 6. Clinical features Initially outlet obstruction: • Weak stream, hesitancy, intermittency, dribbling, straining to void, acute urinary retention Subsequent detrusor instability: • Frequency, urgency, nocturia, dysuria, urge incontinence Finally detrusor failure and chronic retention: • Palpable (or percussible) bladder, overflow incontinence • Enlarged smooth prostate on digital rectal examination
  • 7. • Narrowing of urethra • Hesitancy at the beginning • Desire to urinate but unable to do so • Dysuria • Salasul bole (incontinence) • Bole ud dam • Ihtibas e bol • Bad odour of urine • Sleep disturbance
  • 8. Investigations • Basic investigations • Urinalysis and urine culture for evidence of infection or haematuria. • FBC: infection. • U+E and serum creatinine: renal function. • PSA: suspicion of underlying malignancy.
  • 9. Further investigations • Voiding diary. • Uroflowmetry and residual volume measurement (normal <100 ml): evidence of obstruction. • Ultrasonography of kidneys and bladder: structural abnormalities. • Transrectal ultrasound: to determine prostate size. • IVU: structural abnormalities. • Cystoscopy.
  • 10. Complications (of surgical treatment) • Postoperative haemorrhage and clot retention. • UTI. • Retrograde ejaculation, impotence. • TURP syndrome: in 2% of patients absorption of irrigation fluid via venous sinuses in the prostate causes hyponatraemia, hypotension and metabolic acidosis. • Incontinence. • Urethral stricture.
  • 11. ESSENTIAL MANAGEMENT Medical • Alter oral fluid intake, reduce caffeine intake. • α-Adrenergic blockers (e.g. phenoxybenzamine, prazosin). • Anti-androgens acting selectively at prostatic cellular level (e.g. finasteride). • Intermittent self-catheterization if detrusor failure. • Balloon dilatation and stenting of prostate (unfit patient).
  • 12. Surgical • Majority of patients are treated surgically. • Surgical removal of the adenomatous portion of the prostate. • TURP with electrocautery or laser. • Thermal ablation of prostate. • Open prostatectomy if large which may be transvesical or retropubic.
  • 13. Usool-e-ilaj • Eliminate the cause • Stop alcohol • Reduce the kasarat e mubasharat • Avoid extreme hotn and cold • Mudir-e-bole • Daf-e-tasannuj • Muhallil • Daf-e-tafoon • Abzan • Dalak • Qabizat (cautious)
  • 14. Ilaj • Balooti 5 g with milk or water • Jawarish-e-zarooni 5 -10 g • Majoone dabeedul ward 5 g along 60 ml of arq-e-mako • Majoon-e-masikul bole
  • 15. • Lunuwarana pothu kasaya 12 kalang • Chandrabrabawati - P2 m & e • Thripala choorna - 1 tsp m & e • Vasti – Narayana thaila : Dashamula kasaya = 1:5 or Narayana alone • Apply Dasanga lepa + siyambala kola