This document provides guidelines for management of well newborns in the nursery. It outlines procedures for examination and screening of newborns, management of common conditions, guidelines for observation and discharge. Risk factors requiring longer observation or follow up are defined. Procedures for identifying and managing various issues such as jaundice, feeding problems, and abnormalities are described.
1. Author: Sitratullah O Maiyegun MD
Editors: Namrata Singh MD
Maria Villanos MD
Jesus Peinado MD
Ashish Loomba MD
Well baby Nursery Director: Carmen
Prieto MD
07/03/13 1S O MAIYEGUN MD
2. The guidelines do not indicate an exclusive
course of treatment or serve as a standard of
medical care
Appropriate management can be modified
according to individual circumstances
Please apply evidence based medicine as
appropriate
07/03/13 2S O MAIYEGUN MD
3. Evaluate well newborns with history, physical
exam and routine screening procedures, and
provide preventive counseling and intervention
as indicated
Manage breast and formula feeding in the
newborn period
Evaluate and manage common conditions and
infections in the normal newborn
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4. Recognize and manage jaundice in the newborn
period
Provide anticipatory counseling at nursery
discharge that relates to newborn behavior,
family adjustment, injury prevention, and access
to medical services
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5. Wash hands before and after examining any
infant
All babies must be examined within 24 hours of
birth
All admission orders (entered by nurses) must
be signed
Maternal prenatal lab results and GBS status,
and mother and infant’s blood types
HIV, RPR and Hep B status must be updated
within 12 hours of delivery
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6. Admission and discharge diagnoses to be
documented with problem lists
Update maternal labs prior to discharges
Any abnormal results reported to the intern must
be reported to the senior and/or faculty
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7. Birth weight < 2250 gms
Gestational age < 35 wks
Apgar score of <5 at 5 mins
Prolonged period of abnormal transition (more
than 4 hrs )
Initial Se. Glucose <30 mg% (after ISTAT)
Maternal chorio detected in L&D
Initial rectal temp 102 F or more
Unstable baby in L&D or OR
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8. All babies will be placed skin-to-skin with mom
for breastfeeding for as long as they are stable
Nursing procedures and further assessment will
be done while with mom
Babies will be transferred to room with mom
from L&D
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9. Babies of diabetics and moms on magnesium
will also be placed skin-to-skin unless otherwise
symptomatic or per pediatrician order
After skin-to-skin they will go to the NBN for
further assessment or stay with mom if mom is
stable
Stable C/S babies stay with the relatives in
OR /L&D till mom is able to handle the baby
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10. Maternal history of diabetes, Fever
PROM >18hours (CDC, AAP)
<37wks
Weight ≥3800 gms and ≥2500gms
LGA >90th
percentile or SGA/IUGR < 10th
percentile for weight
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11. Blood glucose within 30mins-1hour of admission
in high risk babies
Peripheral hematocrit: in high risk babies
Eye prophylaxis with 0.5% erythromycin
ophthalmic ointment
Vitamin K 1mg IM X1
Hepatitis B vaccine X1( after consent)
Cord blood studies if mother is O+ or Rh (-)
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12. Radiant warmer in the nursery until stable to
transfer to mom’s room
If needed , formula feeds need to be prescribed
( Baby-friendly policy)
Normal delivery24hours observation if all
discharge criteria fulfilled
If risk factors 48hours
C/S delivery observe for 48hrs
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13. Breastfed and formula fed infants should be
supplemented with 400 IU/day of vitamin D
beginning in the first few days of life
Supplementation should be continued unless
the infant is weaned to at least 1 L/day vitamin
D–fortified formula (1 or 2 months)
1liter of regular infant formula(406 IU of Vitamin
D)
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14. Newborn hearing screen before discharge
If failed Algo X2Refer for BAER
Newborn screen at 24hrs of life
Jaundice meter reading upon admission and q
shift until discharge
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15. History
Adequate prenatal care≥ 4 visits
Maternal age > 17years
No maternal drug use
Mother not A1or A2 diabetic
Mother not GBS+ or Chlamydia +
Mother not RPR+, HIV +, HepB/C +
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16. Delivery
Vaginal delivery in the hospital
Rupture of Membranes < 18hours (CDC)
No maternal temperature >101 or concern
regarding chorioamnionitis
Apgar score at 5minutes at least 7
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17. Examination
Gestational age of at least 37weeks
Baby is not on 24-hour glucose series (LGA,
SGA or initial hypoglycemia)
No physical findings that requires further
monitoring
Vital signs are documented as being within
normalranges and stable for the last 12 hours
preceding discharge
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18. No vital signs abnomalities: No Temp instability,
RR<60, HR 100-160, axillary temperature of
36.5°C to 37.4°C (97.7°F to 99.3°F)
No Jaundice in the first 24hrs
The clinical significance of jaundice, if present
before discharge,has been determined, and
appropriate managementand/or follow-upplans
have been put in place
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19. No Jaundice in the first 24hrs
The clinical significance of jaundice, if present
before discharge,has been determined, and
appropriate managementand/or follow-upplans
have been put in place
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20. No history of poor feeding or emesis
Able to coordinate sucking,swallowing, and
breathing while feeding
Normal voiding and stooling pattern
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21. Labs
No Glucose issues during the first 24hrs
Bilirubin in the normal range as per risks
Maternal RPR, HIV, HBsAG status known
If Rubella non-immune inform OB resident to
make sure mom is vaccinated PTD
No ABO setup, baby is Coombs negative
Algo hearing test done (otoacoustic emission)
done
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22. Psychosocial
At least 2 successful feedings without the help
of nurses (lactation consult if needed)
Good maternal-baby bonding, no maternal
depression
No nursing concerns
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23. ◦ Cord, skin, and genitalcare for infant
◦ Ability to recognize signs of illness and
common infant problems,particularly jaundice
◦ Proper infantsafety (proper use of a car safety
seat andsupine positioningfor sleeping)
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24. Teenage mothers <17 yrs with or without
prenatal care
Teenage mothers <17 yrs without a family or
support system in place or other specified
problems (i.e. depression, lack of planning,
bonding)
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25. Mothers with substance abuse (present +
screen or previous)
Mother with previous hx of post-partum
depression
Discharge against medical advice
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26. Early discharges < 48 hours follow-up within 1
to 2 days or 72 hours (earlier visit not possible)
If no risk factors, clinically well d/c after 24
hours
If risk factors are present, clinically not well
appearing, required limited evaluation d/c
after 48 hours
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28. Problem-
◦ Any deviation from completely normal external
male or female genitalia
Clitoral enlargement (> 1.0 cm)
Labioscrotal fusion of any degree
Hypospadias (penoscrotal, scrotal or perineal
)
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29. Any degree of hypospadias with unilateral or
bilateral cryptorchidism
Micropenis (stretched length < 2.5 cm)
Bilateral cryptorchidism ( with other
anomalies )
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30. 30
Please do not include prominent labia minora
in a preterm
Check the gestational age!!!!!!!
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31. First degree (glandular): urethral meatus opens
on the underside of the glans penis in about 50–
75% of cases
Second degree(Midshaft) :when the urethra
opens on the shaft
Third degree (penoscrotal and perineal): when
the urethra opens on the perineum) occur in up
to 20 and 30% of cases respectively
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34. Severe degrees are more likely to be associated
with chordee
The phallus is incompletely separated from the
perineum or is still tethered downwards by
connective tissue, or with undescended testes
(cryptorchidism)
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35. 35
Hypospadias ( 1st
and 2nd
degree) with
palpable testicles
Observe and referral to urologist outpt
No need for US kidneys (develops from
genital tubercles)
Advice against circumcision (prepuce for
repair)
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37. Plan-
No gender assignment until after endocrine
consult
◦ As soon as possible after birth
U/S abdomen ( uterus, testes, adrenals)
Karyotype
17-OH progesterone
Electrolytes BMP ( virilization )
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38. LH, FSH, Testostorone, dihydrotestostrone,
DHT,
Peds endo consult stat !!!!
Parent education and counseling !!!!
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39. Problem-
◦ Initial HCT of <40 mg% (spun Hct)
◦ Pale newborn
Plan-
◦ Do PE & check for symptoms ( splenomegaly,
tachypnea, tachycardia, shock, CHF, murmur )
—if present consult attending
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40. Plan-
◦ Check maternal history
Severe prenatal anemia
Perinatal blood loss
3rd
trimester bleeding
Maternal blood type & antibody screen
Abruptio placenta or placenta previa
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41. ◦ Check birth history
Asphyxia & Apgar scores
Delivery method & special circumstances
Plan-
◦ Lab w/u-
CBC & peripheral smear
Retics count, fractionated bili
Blood type & Coombs
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42. Plan-
Maternal Kleihauer Betke test (request OB
resident to order)
Repeat HCT in 12-24 hrs – if decreasing
notify attending ( may need head &/or
abdominal US- liver/adrenal hemorrhage)
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44. Problem-
◦ Blood streaked diaper with normal stool
Plan-
◦ Check for-
◦ Clinical activity
Small laceration/fissure or area of irritation in
anal area
Abdominal distention
Other symptoms (poor feeding , vomiting
etc.)
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45. Plan-
◦ If no fissure-
Stool for occult blood
Stool for culture, WBC and rotavirus
Stool for reducing substance
**Apt test (send-out) take a while to get result
If maternal blood – f/u
If fetal blood – discuss with attending
Make sure Vit K has been given
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46. CBC with diff :
◦ inflammatory response
◦ thrombocytopenia
◦ anemia
If abdominal distention
Stat KUB
Stat CBC & CRP
Discuss with attending
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47. Problem-
◦ Infant not moving arm ; arm & held limply
extended to the side with hand flexed
◦ Erb-Duchenne palsy (C5 - C6)
◦ Klumpke’ s paralysis ( C7-8 , T1)
Plan –
◦ Examine infant-
Clavicular crepitus
Presence of grasp ( absent in Klumpke’s)
Assoc. resp distress ( Erb’s) ; Horners synd
( Klumpke’s)
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49. Plan-
◦ Cxr with clavicles
If clavicle fractured –immobilize arm
F/u outpt with Orthopedics
◦ Physical Tx consult as outpt
◦ Neurology consult as outpt if severe Erb’s
palsy
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51. HR=85-160bpm (0-24hr) 100-175bpm(1-7days)
or > 2SD above the mean for age, asleep or
awake
HR persistently < 80-100/min(awake),<70-
90/min(asleep) and/or dropped beats
Dropped or skipped beats
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52. Plans:
Maternal Hx of SLE
Ionized Ca with BMP(K+)
EKG and CXR (pneumothorax/heart shape)
Cardiac consult
Echo after discussion with the attending
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54. 54
Molding of the head
Crosses the suture lines
Subcutaneous soft tissue swelling
Poorly defined margins
Usually resolves over the first few days
Observation
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55. Subperiosteal hemorrhage
◦Unilateral or bilateral, most commonly over
parietal bone, rarely the occipital bone
◦Firm swelling or fluctuant
◦Limited by suture lines/ does not cross the
suture lines
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56. Plan-
◦ Obtain delivery history: SVD, forceps and
vacuum
◦ Check for jaundice q 12hrs (J-meter)
◦ Discuss with mother- reassurance
May be felt till 3 mos of age & may calcify
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61. If large or bilateral, CNS signs, difficult delivery,
depressed skull fracture AP & Lat skull X-
Rays or CT head( discuss)
If Hct dropped rapidly inform attending
US head or CT head to r/o ICH/IVH
◦ PT/PTT, CBC (Immune
thrombocytopenia)
◦ If signs of shock IMCN
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62. There is increased risk of intracranial
hemorrhage among infants delivered by vacuum
extraction or forceps or unassisted vaginal
deliveries (or prolonged labor )
ICH: subdural or cerebral hemorrhage,
intraventricular hemorrhage, subarachnoid
hemorrhage
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63. Problem –
◦ Shoulder dystocia @ birth
◦ Tenderness , swelling over clavicle
◦ Crepitus over clavicle
◦ Decreased movement of arm
Plan—
◦ X-rays of clavicle
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64. It may be asymptomatic
Generally, there is no treatment other than lifting
the child gently to prevent discomfort
The arm on the affected side may be
immobilized by pinning the sleeve to the
clothes (Swaddle / immobilize)
Orthopedic referral as out-patient, if severe
as in-patient ( discuss with attending)
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66. DD: partial dislocation of the elbow, Erb palsy,
fractured humerus
Reassure mother and inform about subsequent
callus formation
Full recovery usually occurs without treatment
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67. Problem-
◦ Abnormal buccal cavity
◦ Maybe unilateral , bilateral or midline
◦ Maybe mild , severe or partial
◦ Maybe submucosal with bifid uvula
Plan-
◦ Obtain fam hx ,prenatal hx (meds)
◦ If midline head U/S to r/o
holoprosencephaly
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69. Plan-
◦ Assess feeding
Special nipple- Haberman nipple
No bottle propping
Feed in upright position
Occupation therapy (OT) consult
Plastic surgery consult as outpatient
Genetics consult as outpatient if indicated
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71. Problem-fixed or flexible (positional)
◦ Forefoot in fixed adduction
◦ Calcaneal tendon is shortened
◦ Foot is inverted with plantar flexion
◦ Inability to correct itself by stroking the outside
& inside of foot (fixed)
Plan-if fixed
◦ Check hips
◦ Ortho consult as in-patient (X-ray, stretching
and serial casting)
◦ Discuss with mother
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72. If flexible (positional) , reassurance and passive
stretching by mother q prn
Any orthopedic abnormalities, discuss with
attending prior to ortho consult
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74. Eye prophylaxis with 0.5% erythromycin
ophthalmic ointment
It is not effective in preventing neonatal
chlamydial conjunctivitis or extraocular infection
Effective for prevention of gonococcal
ophthalmia
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75. Problem-
◦ Newborn with eye discharge
◦ Can be unilateral or bilateral
◦ Possible periorbital edema
◦ Eyelids may be erythematous or appear glued
shut
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76. Plan-
◦ Maternal hx of GC , Chlamydia , Herpes
◦ Delivery hx –( Erthromycin ointment application
, maternal vaginal discharge , PROM)
◦ Evaluate timing of onset , amount ,color,
consistency, tendency to return
◦ Plans;
Gram stain and culture
07/03/13 76S O MAIYEGUN MD
77. Plan-
◦ If Gram stain positive for bacteria or PMN’s ,
discuss with attending
◦ Cleanse eyes with sterile water
Note—
◦ Chemical conjunctivitis—
Develops within hours after birth & resolves
in 36-48 hours
Gram stain negative but PMN’s are present
07/03/13 77S O MAIYEGUN MD
78. ◦ GC conjunctivitis–
Presents usually 1-4 days after birth
Can present within a few hours after birth
Lid edema , copious purulent exudate ,
chemosis , clouding of the cornea
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79. Gm stain PMN’s & intracellular Gm negative
diplococci
Tx – Inform attending for transfer to IMCN for
Ceftriaxone and workup for sepsis
Reportable to Department of Health within
72hours
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80. Ceftriaxone (25-50 mg/kg, intravenously or
intramuscularly, not to exceed 125 mg) given x 1
Cefotaxime x1 (100mg/kg IV or IM) is
recommended for infants with hyperbilirubinemia
Infants with gonococcal ophthalmia should
receive eye irrigations with saline solution
immediately and at frequent intervals until the
discharge is eliminated
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81. Topical antimicrobial treatment alone is
inadequate and is unnecessary when
recommended systemic antimicrobial treatment
is given
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82. Hospitalized and evaluated for disseminated
infection (sepsis, arthritis, meningitis)
Recommended therapy for arthritis and
septicemia is ceftriaxone or cefotaxime for 7
days, if meningitis is document treatment should
be continued for a total of 10 to 14 days
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83. ◦ If late onset > 1st
24 hours of life or suspected
causes other than reaction to eye prophylaxis
Gram stain & culture
◦ Chlamydia conjunctivitis—
Presents 5-14 days after birth
Purulent discharge, eyelid edema &
conjunctival inflammation
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84. Conjunctival scraping for Chlamydia:
Infectious disease consult
Reportable to Department of Health within
72hours
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85. If mom is Chlamydia positive and with or
without treatment
Baby is asymptomatic no treatment FU
in out-pt for signs of infection
Prompt treatment of mother and her sexual
partner(s)
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86. Oral azithromycin for 5 days or erythromycin
base or ethylsuccinate for 14 days +
erythromycin eye ointment
If unstable and severe respiratory IV
erythromycin after evaluation for sepsis in IMCN
Infantile hypertrophic pyloric stenosis (IHPS) in
< 6weeks (erythromycin)
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87. Problem—
◦ Infant with soft or ping-pong skull
◦ Usually over temporo-parietal region & along
suture lines
◦ Causes-
Hydrocephalus ,OI ,syphilis, rickets ,
hypervitaminosis A , normal variation (sagittal
suture craniotabes in premies)
07/03/13 87S O MAIYEGUN MD
88. Plan—
◦ Maternal Hx– infections , medications , family
history
◦ Transilluminate skull
◦ Head US & skull X-rays – if needed
◦ Check maternal RPR – if positive follow
syphilis protocol
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90. 90
Problem-
◦ Hip “clunk”
◦ Positive Barlow or Ortolani sign
◦ Unequal thigh/gluteal creases or leg lengths
◦ Strong family history
◦ Breech presentation
SOMAIYEGUN MD
07/03/13 90S O MAIYEGUN MD
91. Plan-
◦ If “click” present re-examine @ D/C
◦ If “click” & + strong family history Ortho
consult
◦ If “clunk” present Ortho consult
◦ U/S hip if needed, will be ordered or advised
by orthopedics
◦ Discuss with mother
◦ FU with PCP
◦ Only ClickRe-check hips in 2 weeks(AAP)
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92. Breech with abnormal click/clunk prior to
discharge Ortho consult or otherwise U/S hip at
4-6 weeks of age and/or radiographic imaging at
4-6 mos (AAP)
US hip screening of all breech newborns will not
eliminate the possibility of later acetabular
dysplasia (AAP)
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93. Problem—
◦ 2 abnormal stools in an 8 hour period
◦ Numerous large watery , foul smelling stools
with blood , mucous
Plan—
◦ Examine baby & review vitals
◦ Look at stool
◦ Send stool for reducing substances,
leucocytes, RBC & culture, rotavirus
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94. 94
If reducing substance positive(+) switch to
soy based formula/ lactose free milk
◦ If stool is watery++ sent stool for electrolytes
◦ BMP
◦ Suspect chloride diarrhea in mom with hx of
polyhydramnios
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95. Plan—
◦ If baby looks sick , abnormal vitals , abdominal
distention get KUB stat , CBC , CRP, BMP
◦ Inform attending
◦ Discuss normal variations in stooling patterns
with mother
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96. Breast fed stools-frequent, without form, may
be mucousy; affected by maternal diet ( fruit ,
laxatives ,medications)
If starvation present may be frequent , small
quantity, dark green
Stools can be less frequent & pasty
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97. ◦ Discuss normal variations in stooling patterns
with mother
Breast fed stools-frequent, without form ,may
be mucousy; affected by maternal diet ( fruit ,
laxatives ,medications)
If starvation present may be frequent , small
quantity, dark green
Stools can be less frequent & pasty
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99. 3-8% of NB
The possibility of occult spinal dysraphism
(OSD) is more likely if above the gluteal cleft
(truly sacral in location) because they are more
likely to be contiguous with the dura
Within the gluteal fold: less likely to be
contiguous with the dura and are much more
likely to be a normal variant
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100. Simple or low risk :
Position – within the gluteal fold or coccygeal
position
Single dimple
< 5 mm diameter
Base of dimple is visible
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101. Dimple is oriented straight down (i.e. caudal) not
cephalically (i.e. toward the head)
No other dermal abnormalities or masses
Distance < 2.5 cm from anus
Normal neurological examination
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102. Difficult to clearly distinguish all variations
consider the individual circumstances
Plan: U/S spine
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103. Midline / vertebra appearance of significant
tuft of hair ,hemangioma or nevus
Plan: U/S spine
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104. Discharge diagnosis is very important
Make an assessment regarding what
observation and treatment the infant needs and
discuss findings with the parents
Explain to the parent(s) of the possible
consequences for their infant if they leave e.g
sepsis, jaundice
Explain the need for FU in 1 or 2 days and ER
warnings
Consult with the social worker (SW)
07/03/13 104S O MAIYEGUN MD
105. If medical diagnosis or concerns exist which
may result in immediate harm to the infant
Remind parent(s) that their action is contrary to
the welfare of their infant and that Department
for Child Protective Services (CPS) will be
notified
Child can be kept in the holding nursery if
mother wants to go home
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106. Consult with the social worker (SW)
They will make an assessment and consult with
CPS or Crisis Care (after hours/weekends) as
necessary
CPS hold statutory powers and have the
authority under the Children and Community
Services Act 2004 to protect the welfare, care
and protection of children
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108. Infant with features of Down syndrome
◦ Talk to the family (mom)
◦ No d/c prior to 48 hrs of age
◦ Evaluate feeding / vomiting (duodenal atresia)
◦ Glucose series (hypoglycemia)
◦ CBC with diff & platelets(polycythemia,
leukemoid reaction or leukemia)
◦ Ensure good follow-up
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109. Karyotype (with informed consent)
◦ Maternal and family history
◦ Echocardiogram prior to discharge
◦ Cardiac consult as needed
◦ Genetics consult as out-patient
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111. Problem—
◦ Grossly abnormal ears
◦ Significant low set and posteriorly rotated ears
◦ Incomplete auricle
◦ No visible ear (anotia)
◦ Multiple significant ear tags (pre-auricular tags)
◦ Pre-auricular sinus/pit with a blind end is not
included
07/03/13 111S O MAIYEGUN MD
114. Plan—
◦ Strong family history of similar defects
◦ Hearing test (ALGO 2) if failed schedule for
BAER test
◦ Renal US to r/o abnormalities after discussing
with faculty
◦ Look for other dysmorphic features and
associations
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115. C coloboma
H congenital heart defects
A choanal atresia
R retardation of growth and development/ CNS
G genitourinary anomalies
E ear and/or auditory anomalies
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116. Newborn with copious oral secretions and
episodes of coughing, choking, and cyanosis
Hx of pregnancy complicated by polyhydramnios
Plans: place an orogastric suction catheter and
obtain a chest radiograph
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117. VACTERL association
V Vertebral or Ventriculoseptal defects
A Anal atresia
C Cardiac anomalies
T/E Tracheoesophageal fistula/ esophageal
atresia
R Radial dysplasia / Renal anomaly
L limbs
3/2/2011 117S O MAIYEGUN MD 07/03/13 117S O MAIYEGUN MD
123. ◦ GBS+ mother with 1 dose of intrapartum abx
< 4hrs PTD CBC and CRP at 24 hrs
◦ GBS+ mother with at least 1 dose of
intrapartun abx > 4hrs PTD asymptomatic
observe for 48hrs
◦ No discharge prior to 48 hrs of age
If baby is unstable CBC/+ CRP (if
>24hr) stat ± transfer to IMCN as
appropriate
07/03/13 123S O MAIYEGUN MD
124. ◦ PROM >18hrs (+ intrapartum abx given to
mum), if stable CBC & CRP at 24 hrs and
re-evaluate
◦ PROM >18hrs (no intrapartum abx given to
mum) CBC at birth and CBC & CRP at 24
hrs and re-evaluate
◦ No discharge prior to 48 hrs of age
07/03/13 124S O MAIYEGUN MD
125. ◦ GBS (+)mum, good PNC, term ≥37wks, SVD
◦ Adequate intrapartum antibiotic prophylaxis
(IAP) given
◦ Asymptomatic baby
◦ Mom is able to comply with home instruction for
observation
◦ Can be discharged home after 24hrs if other
discharge criteria are met
◦ If discharge criteria are not met observe for
48hrs
07/03/13 125S O MAIYEGUN MD
126. ◦ Intrapartum antibiotic prophylaxis (IAP)
◦ Adequate if penicillin, ampicillin or cefazolin is
given at the proper doses for four or more
hours prior to delivery
◦ Duration of IAP shorter than four hours and all
other antimicrobial regimens,
clindamycin
Vancomycin
◦ are considered as inadequate because no data
regarding efficacy are available
07/03/13 126S O MAIYEGUN MD
127. Penicillin and ampicillin rapidlyachieve
therapeutic levels in the fetal circulation and
requirethree hours to achieve therapeutic levels
in amniotic fluid
Cefazolin has similar pharmacokinetics and is
the preferredagent for IAP in penicillin allergic
women with no history ofanaphylaxis,
angioedema, respiratory distress or urticaria
07/03/13 127S O MAIYEGUN MD
128. Problem:
◦ No documented PNC or GBS unknown
◦ Prenatal care at lay midwife maternity center
◦ Less than 4 visits starting later than 28th
week
of gestation
Plan—
◦ Check perinatally drawn maternal labs and
please document prior to D/C
07/03/13 128S O MAIYEGUN MD
129. If baby is stable: NO screening with CBC and
CRP at 24 hours
Observe for 48hour in the hospital
If baby symptomatic at anytime
<24hours CBC stat ± transfer to IMCN
as appropriate
If symptomatic > 24hours CBC and
CRP ± transfer to IMCN as appropriate
3/2/2011 129S O MAIYEGUN MD 07/03/13 129S O MAIYEGUN MD
130. ◦ PROM >18hrs (+ intrapartum abx given to
mom), if stable CBC & CRP at 24 hrs and
re-evaluate
◦ PROM >18hrs (no intrapartum abx given to
mom) CBC at birth and CBC & CRP at 24
hrs and re-evaluate
◦ GBS (–)negative in the hospital and NPC
48hrs observation
◦ No discharge prior to 48 hrs of age
3/2/2011 130S O MAIYEGUN MD 07/03/13 130S O MAIYEGUN MD
131. ◦ Any symptoms CBC stat or CBC and CRP if
>24hrs or transfer to IMCN as appropriate
◦ If labs are grossly abnormal CRP>20 x 2 or
CRP >40 X1, WCC>30 or <5, even if clinically
stable, discuss with attending for possible
transfer to IMCN
**48-hour CBC and CRP will be ordered after
24-hour lab is reviewed
07/03/13 131S O MAIYEGUN MD
132. Problem—
◦ Maternal h/o GC during pregnancy
Plan—
◦ Maternal h/o tx & documentation of cure
◦ If inadequate or no documented test of cure
Ceftriaxone 125 mg I/M x 1
◦ No discharge prior to 48hrs
07/03/13 132S O MAIYEGUN MD
134. Problem—
◦ Maternal h/o hepatitis
◦ Mother known HBsAg carrier
◦ Mother @ high risk for being a Hep B carrier
( known or suspect IV drug use , mother from
endemic region)
07/03/13 134S O MAIYEGUN MD
135. Plan—
◦ Verify maternal HBsAg status
◦ If mother positive
◦ Hep B Ig (0.5 cc I/M) within 12 hrs of birth
Hepatitis B vaccine ( 0.5 cc I/M) concurrently
@ different site
Breastfeeding is not C/I
ID consult as outpt
07/03/13 135S O MAIYEGUN MD
136. Plan—
◦ Infants delivered to mothers who are jaundiced
,h/o hepatitis of unknown etiology or who are
in a high risk group & have not been screened
—
Hep B vaccine (0.5 cc I/M ) within 12 hrs of
birth
Verify mothers HBsAg status ; make sure it is
drawn. If positive give HBIG
07/03/13 136S O MAIYEGUN MD
137. Plan—
◦ Mother is Hepatitis C+(anti-HCV-positive )
Order Hep C Ag on baby : (Ig) G antibody
enzyme immunoassays for HCV and NAA
tests to detect HCV RNA
Assays for IgM to detect early or
acute infection are not available
Transmission of HCV by breastfeeding has
not been documented
07/03/13 137S O MAIYEGUN MD
138. Not a contraindication to breastfeeding
Mothers who are HCV positive and choose to
breastfeed should consider abstaining if their
nipples are cracked or bleeding
F/U with ID as outpt to monitor LFT and anti-
HCV
07/03/13 138S O MAIYEGUN MD
139. Problem—
◦ Mother identified as having vaginal herpes
◦ Previous h/o herpes
Plan—
◦ PE of the baby for rash (vesicles)
◦ Delivery hx-C/S or vaginal ( higher risk)
◦ Instruct mother on care of infant (good hand
washing etc)
07/03/13 139S O MAIYEGUN MD
140. Care of infants born vaginally to a mother with
active genital ulcerative lesions. Primary 1st
episode of HSV infection or known recurrent
lesion or status unknown IMCN in isolation
Care of the infant born via C/S to a mother with
active genital ulcerative lesions (primary,
recurrent or unknown) esp if onset of labor or
ROM > 4hoursIMCN in isolation
07/03/13 140S O MAIYEGUN MD
141. Care of the infant born to a mother with a history
of HSV infection and no active lesions at
delivery.
Neither HSV cultures nor empiric therapy with IV
Acyclovir are indicated
No isolation necessary
Care of the infant born by C/S (intact
membrane) and no active lesions at delivery.
No isolation necessary
07/03/13 141S O MAIYEGUN MD
142. A mother with herpes labialis or stomatitis
should wear a disposable surgical mask when
touching her newborn infant until the lesions
have crusted and dried
She should not kiss or nuzzle her newborn until
lesions have cleared
Herpetic lesions on other skin sites should be
covered
07/03/13 142S O MAIYEGUN MD
143. Problem—
◦ Mother’s HIV is positive
Plan If complete HIV testing is pending after
birth and the mom is Elisa positive
Western Blot (WB) still pending then breast
feeding should not be initiated until the WB has
been reported negative
◦ If mother’s WB is (+)
◦ if baby is stable, can start PO AZT
◦ if unstable IMCN to start on IV AZT
◦ If mothers WB is (-) ,no issues
07/03/13 143S O MAIYEGUN MD
144. Plan—
Detailed hx for risk factors
Zidovudine (AZT) must be started 6-12
hours after AZT(8mg/kg/day) PO q6hrs X 6
weeks
Send HIV DNA PCR within the first 48
hours after birth
Cord blood should not be used
ID consult as in-patient
07/03/13 144S O MAIYEGUN MD
145. Plan—
If hx inconclusive
ID consult
FU on HIV DNA PCR in baby
07/03/13 145S O MAIYEGUN MD
146. Maternal history of diabetes, Fever
PROM >18hours (CDC, AAP)
<37wks
Weight ≥3800 gms and ≥2500gms
LGA >90th
percentile or SGA/IUGR < 10th
percentile for weight
07/03/13S O MAIYEGUN MD 146
147. All high risk babies are screened with blood
glucose
Regardless of gestation a serum glucose <
40 mg/dL is hypoglycemia
A serum glucose < 45 mg/dl if symptomatic will
be treated as hypoglycemia
07/03/13 147S O MAIYEGUN MD
148. Glucose level less than 30mg/dL (<30mg/dL) by
I-STAT will be admitted to EPCH
Treatment will not be postponed
Newborns will be formula fed as medically
indicated for hypoglycemia less than 30mg/dl
prior to admission to EPCH at 10ml/kg
07/03/13 148S O MAIYEGUN MD
149. Pre-prandial serum glucose q 3 hours during the
first 24 hours of life
Glucometer and confirmed by I-STAT if level is
less than 40mg/dl
07/03/13 149S O MAIYEGUN MD
150. Glucose Series =>
Glucose level > 30mg/dL but < 40 mg/dL
immediate feeding and a repeat glucose 30 to
60 minutes after feeding
If repeat glucose is > 40mg/dL monitor pre-
prandial glucoses and oral feedings every 3
hours for 24 hours
07/03/13 150S O MAIYEGUN MD
151. Glucose is < 40mg/dL after initial feeding, and
result after one hour postprandial retesting is still
< 40mg/dL transfer to EPCH
Glucose level > 40mg/dL will be treated orally by
breastfeeding every 1 to 3 hours expressed
formula and/or house formula every 2-3 hours
07/03/13 151S O MAIYEGUN MD
152. Breastfeeding shall occur every 1 to 3 hours and
on demand
If at 24 hours preprandial glucoses are < 50
mg/dL, preprandial glucose should be monitored
another 12 hours
If preprandial glucoses are < 50 mg/dL at 36
hours, the Newborn will be transferred to EPCH
for further evaluation
07/03/13 152S O MAIYEGUN MD
153. Problem—
◦ Infant with enlarged scrotum
Plan—
◦ PE to palpate testes
◦ Transilluminate, if unable to palpate testes
◦ If scrotum is hard , indurated & discolored
Doppler U/S of testes
◦ Doppler U/S Testicular torsion surgery
consult immediately
07/03/13 153S O MAIYEGUN MD
156. Problem—
◦ Evidence of hydronephrosis on prenatal ultrasound
◦ Enlarged palpable kidneys on PE
◦ Hydronephrosis on US done for other anomalies
07/03/13 156S O MAIYEGUN MD
158. 158
Plan—
◦ Check voiding—if no void in 24 hrs
transfer to IMCN
◦ Minimal hydronephrosis grade 1 US and
reassurance if still minimal or negative
◦ If no urine >24hrs UA , BMP and follow
protocol for anuria >24hrs
07/03/13 158S O MAIYEGUN MD
159. ◦ Moderate hydronephrosis grade 2 US, if still
moderate VCUG, If no urine >24hrs UA ,
BMP
◦ If VCUG is abnormal discuss with attending for
Mx, prophylactic abx
◦ Urology referral as out-pt or in-pt as
appropriately
07/03/13 159S O MAIYEGUN MD
160. 160
Plan—
◦ Grade 3 and 4 IMCN ( US, UA , BMP
,VCUG) discuss with attending & mother
◦ Urology referral as in-pt or out-pt as
appropriate
◦ Outpatient: FU U/S in 6 weeks (mild and
moderate) and if still abnormal VCUG
Urology referral as outpt (MAG3)
07/03/13 160S O MAIYEGUN MD
161. Problem –
◦ Rectal temp > 101.0
Plan –
◦ Unwrap pt & repeat temp in 30 mins
◦ Review maternal hx ( GBS , PROM , fever , s/s
of chorio )
If positive CBC stat or CBC & CRP if > 24
hrs
◦ If temp not decreased in 2 hrs – inform
atttending for transfer to IMCN
07/03/13 161S O MAIYEGUN MD
162. Plan –
◦ Transfer to IMCN if symptomatic @ any time ,
temp > 102 , abnormal CBC or CRP > 20 or
rising
◦ IT ratio >0.2
◦ No d/c before 48 hrs of age
07/03/13 162S O MAIYEGUN MD
163. Problem—
◦ Infant with increased muscle tone
Plan—
◦ Perinatal hx for asphyxia , traumatic delivery ,
dysmorphic features
◦ Suspect drug withdrawal-
Maternal hx
Urine/Mec tox screen in baby
Watch for other signs of withdrawal
07/03/13 163S O MAIYEGUN MD
164. Plan—
◦ CT scan of head ( structural abnormalities,
hemorrhage )
◦ If dysmorphic features karyotyping
◦ No D/C prior to 48 hrs of age
07/03/13 164S O MAIYEGUN MD
165. Problem—
◦ Infant with rectal temp < 97.6
Plan –
◦ Evaluate environmental conditions
◦ Check gest age , weight , feedings
◦ Check maternal hx for possibility of ascending
infections
◦ Place under radiant warmer & check rectal
temp in 30 mins
07/03/13 165S O MAIYEGUN MD
166. Plan—
◦ If persistent low temps > 2hrs – CBC , CRP
◦ If results abnormal transfer to IMCN
◦ If 2 temp drops CBC stat or CBC& CRP if >
24hrs If results abnormal ,transfer to IMCN
◦ If 3 temp drops transfer to IMCN
07/03/13 166S O MAIYEGUN MD
167. Problem—
◦ Floppy infant
Plan—
◦ Complete CNS exam
◦ Maternal narcotic admn in last 4hrs PTD
I/M Narcan ( 0.1 mg/kg )
◦ Maternal h/o of MgSO4 tx for PIH
If present – magnesium level
07/03/13 167S O MAIYEGUN MD
168. Plan—
◦ Birth h/o asphyxia ; apgar scores
◦ Check feeding
◦ Lab w/u—
Mg , glucose , HCT , CBC ,CRP
Head US (consult attending )
◦ Discuss with mother
◦ No d/c home prior to 48 hrs of age
07/03/13 168S O MAIYEGUN MD
170. Problem—
◦ Maternal h/o diabetes
Plan—
◦ PE for associated anomalies
◦ If no stool – discuss with attending
◦ Place on glucose monitoring series
If 2 drops in glucose ( <40 mg %) while on
the series , transfer to IMCN
If glucose is < 30 mg% at any time transfer
07/03/13 170S O MAIYEGUN MD
172. Plan—
◦ Check HCT
If > 65 ( central ) and symptomatic transfer
to SCN
◦ If jittery , check Se calcium & glucose at once
◦ Discuss with mother
◦ No d/c prior to 48 hrs of age
07/03/13 172S O MAIYEGUN MD
173. Problem—
◦ Maternal h/o substance abuse during
pregnancy
◦ Maternal h/o substance abuse
◦ Maternal s/s suggestive of drug or alcohol use
◦ Positive toxicology in mother
◦ Unexplained irritability /jitteriness in baby
07/03/13 173S O MAIYEGUN MD
175. Plan—
◦ Observe infant for s/s of withdrawal
◦ Check mother’s urine tox
◦ Send meconium and urine tox screen in baby
◦ If h/o cocaine use during pregnancy and urine
tox is positive in baby transfer to IMCN
07/03/13 175S O MAIYEGUN MD
176. ◦ If h/o marijuana use & urine tox is negative in
baby, observe in MB for 48hrs
◦ If h/o amphetamine use during pregnancy or
urine tox is positive in baby IMCN
◦ If negative amphetamine in baby’s urine tox
screen observe in MB for 48hrs
07/03/13 176S O MAIYEGUN MD
177. Plan –
◦ If baby’s & mother’s tox screen is negative –
observe in MB
◦ Check maternal HBsAg & HIV status
◦ ***Social service consult
◦ If any signs of withdrawal ,discuss with
attending or transfer to IMCN
◦ No d/c prior to 48 hrs of age
07/03/13 177S O MAIYEGUN MD
182. Plan—
J-meter q shift
Rh & ABO incompatibility J meter q 6 hrs or
12 hrs and T.bili and retics count earlier (6hr) or
at 24hrs (depending on severity)
If retics is high and bili increasing Hct earlier
(6hr) or at 24hrs ( depending on severity)
07/03/13 182S O MAIYEGUN MD
183. ***If any child is jaundiced in the 1st
24 hrs of life
and J-meter is above the curve
Do initial total bilirubin ,if above the curve as
per the risks in the child plan for
phototherapy (PT)
If below the curve as per the risks then FU J-
meter q shift and fractionated bili q 12 hrs as
necessary
07/03/13 183S O MAIYEGUN MD
184. If concerning do F.Bili q 4-6 hrs and decide
If the rate of rise is greater than 0.5mg/dl/hr
or above the appropriate curve plan for PT
If set-up for sepsis discuss transfer to
IMCN
07/03/13 184S O MAIYEGUN MD
185. Obtain informed consent from mother prior to PT
Start PT as per jaundice chart
Use total bilirubin (do not subtract direct
bilirubin)
Keep baby naked (genitalia and eyes covered)
Monitor temperature and thermal environment
Monitor input/output and increase fluid intake by
10ml/kg/PT
07/03/13MAIYEGUN MD 185
186. Provide irradiance of at least 4µW/cm2/nm
Provide irradiance 30 4µW/cm2/nm or > if
intensive PT is needed
Use double or triple light with biliblanket if level
is high or rapidly rising
Brief interruption for feeding will not interfere
with PT
07/03/13MAIYEGUN MD 186
187. Lab w/u in infant’s under phototx—
◦ CBC at 24hr of life ; retics count (ABO or Rh)
◦ Follow F. bili q 6-12 hrs
◦ If bili rising then order hct and retics
◦ BMP ± Urine SG (dehydration)
◦ Urine reducing substance ( if Coombs neg) r/o
galactosemia
07/03/13 187S O MAIYEGUN MD
188. ◦ Peripheral smear ( if Coombs neg and severe),
spherocytosis (Fx Hx) ,fragmented RBCs in
hemolysis
◦ If African/Asian/ Middle Eastern and severe
and Coombs neg G6PD assay
◦ If there is setup for sepsis or abnormal labs
discuss for transfer to IMCN
07/03/13 188S O MAIYEGUN MD
189. ◦ Discontinue phototx
when bili decreases 2 consecutive times
check bili at 12 hrs after stopping phototx
(d/c home if rebound does not exceed 3.0
mg/dl)
Direct bilirubin > 20% of total bilirubin (Tbili)
07/03/13S O MAIYEGUN MD 189
190. ◦ If direct bili rising, please inform attending
Direct hyperbili >20% of the total bilirubin is
abnormal at any age
◦ Urine reducing substance (galactosemia)
◦ UA for bilirubin
◦ No PT or discontinue
◦ Physical exam (hepato-splenomegaly)
◦ Discuss for transfer to IMCN for further work-
up
07/03/13 190S O MAIYEGUN MD
193. Jitteriness is not associated with ocular
deviation
Generalized and symmetrical
It is stimulus sensitive (easily stopped with
passive movement of the limb by holding onto
the baby’sarm)
Also becoming most prominent after startle
The movement resembles a tremor, and no
autonomic changes are associated with it
07/03/13 193S O MAIYEGUN MD
194. Plan—
◦ Maternal h/o drug use, diabetes,infections
◦ Check initial CBC stat or CBC & CRP at
24hrs, if set-up for sepsis
◦ Urine and mec toxicology screen
◦ Ionized Ca , glucose level
◦ If severe, check Mg ,Phosphate, Parathyroid
hormone (PTH)
07/03/13 194S O MAIYEGUN MD
195. Plan—
◦ Discuss with attending if CBC ,CRP abnormal
◦ Hypocalcemia: If Se Ca is < 2.0mmol/L
(8.0mg/dl) and ionized calcium < 1.0mmol/L
(4.0mg/dl) in symptomatic NB discuss
◦ Se calcium < 7.0 mg /dl and ionized calcium <
0.9mmol/L (3.6mg/dl) asymptomatic discuss
07/03/13 195S O MAIYEGUN MD
196. ◦ If Se Magnesium < 1.0 mg/dl with
hypocalcaemia –discuss for transfer
◦ If Se Glucose < 40 mg/dl --- follow glucose
protocol
◦ FU results for discussion
07/03/13 196S O MAIYEGUN MD
200. Problem—
◦ Head circumference > 38.0 cm
◦ HC disproportionately greater than 50th
% tile to
BW & length
Plan—
◦ Check HC yourself
◦ Family hx of large heads
◦ Maternal h/o TORCH infections
◦ Check head for split sutures
07/03/13 200S O MAIYEGUN MD
202. Plan—
◦ Head US if abnormally split sutures
◦ Transilluminate skull
◦ If transillumination positive or hydrocephalus
present, inform attending for discussion
◦ CT head as needed
07/03/13 202S O MAIYEGUN MD
203. Mom given MgSO4:
If term baby, stable in nursery or MB and
asymptomatic: NO serum magnesium
necessary, but monitor closely
If symptomatic (preterm, poor feeding, low apgar
scores, apnea, resp distress or frequent
desaturation, cyanosis, no meconium in
>48hours) then serum magnesium ± transfer
to IMCN/ICN as appropriate
07/03/13 203S O MAIYEGUN MD
204. No meconium in >48hours
99% of term and 76% of preterm pass stool in
the 1st
24hrs
99% of preterm pass stool in the 48hrs
Plans :
Medications in mother: MgSO4, opiates
Imperforate anus, intestinal obstruction,
hirschsprung disease, malrotation, meconium
plug/ileus, duodenal atresia, small left colon
syndrome (IDM)
07/03/13 204S O MAIYEGUN MD
205. PE: Document patency of the anus (rectal
thermometer or feeding tube
Abdominal exam ( distension, rigidity, BS, mass)
CBC stat or CBC& CRP if set up for sepsis
KUB stat
If Hx of drug use urine and mec tox screen
S. magnesium level if maternal MgSO4
FT4 and TSH
07/03/13 205S O MAIYEGUN MD
206. If all labs normal, If no meconium > 48 hours
consider barium enema to evaluate for
Hirschsprung disease
Surgical consultation for rectal biopsy
***Discuss the use of suppository after 48hours
with attending
No discharge until passage of stool
07/03/13S O MAIYEGUN MD 206
207. Problem—
◦ Infant with small head ( HC <10%ile) or greater
than 50th
percentile difference between head &
weight /length
Plan—
◦ Maternal hx for TORCH infections , drug or
alcohol use ,Rxn drugs ( phenytoin)
◦ Fam hx of small heads & MR
07/03/13 207S O MAIYEGUN MD
208. Plan—
◦ Head US /CT scan
◦ If needed Total IgM for TORCHES & Urine
culture for CMV
◦ Discuss with faculty
07/03/13 208S O MAIYEGUN MD
209. Perinatal Hx
Exam for resp distress
Pulse ox stat and continuous as needed
CXR to r/o abnormalities
CBC stat or CBC& CRP(>24hrs) if set up for
sepsis
If significant abnormal results consider
transfer to EPCH
If grunting (discuss and consider transfer)
07/03/13S O MAIYEGUN MD 209
211. Apparently healthy infant noted to have heart
murmur on PE
Grade 1-2 murmur @ birth
Acyanotic with no significant problems ,re-
examine @ 2nd
day of life
Grade 3-4 on day 1 or significant murmur found
on 2nd
day of life
07/03/13 211S O MAIYEGUN MD
212. Plan—
◦ Full cardiac exam
4 limb BP’s
Pulse ox- spot or continuous as
appropriate
Hepatosplenomegaly
Feeding
CXR (cardiac shape)
Echocardiogram (specific and diagnostic)
◦ EKG as needed
07/03/13 212S O MAIYEGUN MD
213. Plan—
◦ Cyanosis or severe respiratory distress
transfer to IMCN
◦ Grade 1-2 murmur on 1st
day of life with
symptoms
◦ Discuss with faculty for possible transfer to
IMCN/ICN
07/03/13 213S O MAIYEGUN MD
215. Problem—
◦ Red/purple , non-blanching spots on skin/ face
Plan—
◦ Maternal hx of TORCH infection or at risk for
ascending infection
◦ Maternal labs –thrombocytopenia
◦ CBC stat and CBC and CRP at 24hrs
◦ Perinatal h/o asphyxia , nuchal cord , trauma ,
forceps
◦ Observe for signs of sepsis & discuss with
attending
07/03/13 215S O MAIYEGUN MD
216. All high risk babies are screen with capillary
hematocrit
Central venous hematocrit >65%
If capillary hematocrit is more than 65%
repeat from central venous from a cubital vein
◦ Central HCT ( no tourniquet , deep vein
, no femoral sticks )
◦ Check for jaundice ; check Se glucose
07/03/13 216S O MAIYEGUN MD
217. Symptoms of hyperviscosity: Plethora
temperature instability
feeding problems
plethora
irritability
lethargy
hypoglycemia
respiratory distress
hypoperfusion
07/03/13 217S O MAIYEGUN MD
218. Central Hct is 65-69% and the infant is
asymptomatic no intervention is warranted,
repeat central Hct at 24 hrs
If ≥ 65 % and the infant is symptomatic IMCN
for partial exchange reduction
If >70% IMCN for a partial reduction exchange
Discuss with faculty
07/03/13 218S O MAIYEGUN MD
219.
220. Ulnar or postaxial polydactyly commonly
isolated in African black children, autosomal
dominant transmission
More frequent in blacks than in whites and is
more frequent in male children
07/03/13 220S O MAIYEGUN MD
221. Ulnar or postaxial polydactyly commonly
isolated in African black children, autosomal
dominant transmission
More frequent in blacks than in whites and is
more frequent in male children
07/03/13 221S O MAIYEGUN MD
222. In contrast, postaxial polydactyly seen in white
children is usually syndromic and associated
with an autosomal recessive transmission
Radial or preaxial polydactyly is frequently
associated with several syndromes
Any other forms of polydactyly/syndacytly/cleft
hand or feet need orthopedic consult
07/03/13 222S O MAIYEGUN MD
223. Problem—
◦ Skin tag or extra digit on healthy infant
◦ Look for other dysmorphic features
◦ Document pre or post-axial polydactyl
Plan—
◦ Inform mother
◦ If skin tag has a thin pedicle tie off with vicryl
suture after obtaining informed consent from
mother
07/03/13 223S O MAIYEGUN MD
224. ◦ Extra digit—
X-rays to document if bone present
◦ If no bone can tie off with vicryl suture after
obtaining informed consent from mother
If bone present refer to pediatrics
orthopedics as outpatient
Any lower limb polydactyl or preaxial need
referral to orthopedics
07/03/13 224S O MAIYEGUN MD
228. Problem –
◦ Mother with positive serology for syphilis
◦ RPR and TPPA
Plan—
◦ RPR on baby
◦ Detailed maternal hx ( confirmatory labs &
treatment hx)
◦ If mothers TPPA negative no issues
07/03/13 228S O MAIYEGUN MD
229. Plan—
◦ If mothers TPPA is positive
◦ detailed h/o treatment
documented evidence of drug used
(Penicillin)
timing of tx
decreased titers 4x after tx
evidence of tx of spouse )
07/03/13 229S O MAIYEGUN MD
230. ◦ Transfer to IMCN for full work-up
◦ If baby’s titer is at least 4 X maternal titer
◦ No h/o tx
Last dose of PCN within the last month prior
to delivery
Drug other than PCN used
No evidence of decreased titers
Possibility of re-infection( no tx of spouse)
07/03/13 230S O MAIYEGUN MD
231. Plan
If mothers TPPA + & documentation of
satisfactory treatment available (follow the CDC
guideline attached)
refer to ID as out-pt after discussion with
faculty
◦ Transfer to IMCN if infants RPR > 1:4 after
discussion with faculty
07/03/13 231S O MAIYEGUN MD
233. Problem—
◦ Maternal h/o SLE
Plan—
◦ EKG ( bradycardia , complete ht block)
◦ CBC (thrombocytopenia/leukopenia/anemia)
◦ Examine skin for rash ,if present – no sun
exposure, self limiting
◦ FU with PCP
07/03/13 233S O MAIYEGUN MD
234. Problem—
◦ Weight < 10%ile for age
Plan—
◦ Determine gestational age
◦ Determine IUGR status
◦ Maternal h/o placental insufficiency , TORCH
infections , nutrition hx ,h/o chronic diseases &
drug use )
07/03/13 234S O MAIYEGUN MD
235. Plan
Place on glucose series
◦ Check HCT
◦ Follow feedings
◦ Follow temperatures
◦ If hx suggestive of TORCH infection –CBC ,
Total IgM & discuss with attending
07/03/13 235S O MAIYEGUN MD
236. Problem—
◦ Stuffy nose , trouble breathing
Plan—
◦ Check patency of nares ( pass 8Fr feeding
tube B/L ) auscultate for air passing through
each nare after blocking the other one)
◦ Pulse ox as needed
◦ Normal saline nasal drops and bulb suction
◦ Bedside Humidifier (cool mist)
07/03/13 236S O MAIYEGUN MD
237. Plan—
Check maternal h/o syphilis ( snuffles)
◦ Follow feedings
◦ If severe discuss with attending
◦ Bedside Humidifier (cool mist) @ home
07/03/13 237S O MAIYEGUN MD
238. Bleeding in the potential space between the
periosteum and the galea aponeurosis
Risk factors as in cephalhematoma
Fluctuant boggy mass and crosses the suture
lines
Hemorrhagic shock and significant
hyperbilirubinemia
Labs for coagulopathy
Close observation, if severe IMCN
07/03/13 238S O MAIYEGUN MD
240. HR persistently more than 160-175bpm or >
2SD above the mean for age, asleep or awake
Plan:
Maternal Hx of thyroid disorder
Fever check temperature
Birth Hx (forceps or vaccum)
EKG stat
CXR and CBC stat and >24hrs CBC and CRP
Inform attending for transfer to IMCN
07/03/13 240S O MAIYEGUN MD
241. Problem—
◦ Infant born with teeth ( loose or firm) ;either
visible or soft mucoid tissue cysts along
alveolar ridge with palpable loose tooth in it
Plan—
◦ If loose talk with mother regarding need for
removal refer to dentist
◦ If well embedded can FU later with dentist
07/03/13 241S O MAIYEGUN MD
243. Problem—
◦ Empty scrotum or hemiscrotum
Plan—
◦ Unilateral cryptorchidism – no intervention
Urology consult as out-pt
◦ Bilateral, with no palpable testes in canal
abdominal US (testes, ovaries, adrenals)
◦ If U/S shows abdominal testes Urology
consult as out-pt
07/03/13 243S O MAIYEGUN MD
244. ◦ Bilateral with palpable testes in inguinal
canal no intervention recheck gestational
age
◦ If no testes on US ambiguous genitalia
protocol
07/03/13 244S O MAIYEGUN MD
245. Problem—
◦ Maternal h/o thrombocytopenia at time of
delivery or during pregnancy
◦ Platelet count< 150,000
Plan: Repeat platelet count before decision is
made
CBC with platelet on baby
◦ If < 50,000 – transfer to IMCN
◦ If > 50,000 – repeat in 24 hrs
◦ Check baby for petechiae ,bruising, oozing
from cord
07/03/13 245S O MAIYEGUN MD
247. 4% of newborns
Can breastfeed without difficulty, but in some
cases, a tight frenulum makes latching on
difficult
No evidence based reason to clip the frenulum
in the nursery
In cases of difficulty feeding , frenotomy may be
indicated
07/03/13S O MAIYEGUN MD 247
248. Problem—
◦ Single umbilical artery
Plan—
◦ Renal US
◦ Check for urination
◦ Check for dysmorphic features
07/03/13 248S O MAIYEGUN MD
251. Urate crystals look different from blood in the
newborn’s diaper but can be confused
They tend to sit on the surface of the diaper and
are iridescent and completely benign
M=F
More observed in boys
07/03/13S O MAIYEGUN MD 251
252. No urine in > 24hrs
100% of neonates pass urine in 24 hours Plan:
Maternal History: olighydramnios (renal
anomalies)
Prenatal history of fetal hydronephrosis, kidney
anomalies
Check L& D papers
MOST likely reason: undocumented void in
the delivery room
07/03/13 252S O MAIYEGUN MD
253. Make sure there is adequate intake, lactation
consult if necessary
Supplement with formula if needed
07/03/13 253S O MAIYEGUN MD
254. If no urine more than 24hrs
Placed a cotton ball between the labia or a urine
bag ( check urine)
Bladder palpable (manual compression may
initiate voiding) if a boy think of PUV
Bladder catheterization If no urine US
bladder, kidneys IMCN for further workup
Check BP, BMP
No discharge until the passage of stool and
urine can be documented
07/03/13S O MAIYEGUN MD 254
255. There is no immediate danger to the baby, so
parents can sign that they do not consent
There is no need for social service consult
07/03/13S O MAIYEGUN MD 255
256. Projectile and forceful, vomiting with feedings
>2, ± abdominal distension/tenderness
Greenish emesis or Bloody emesis
Confirm passage of meconium
Look for dysmorphic features (Down Syndrome)
07/03/13 256S O MAIYEGUN MD
257. Plan: Hx of sepsis set-up
KUB stat (NEC, pneumoperitoneum, double
bubble, etc )
CBC stat or CBC & CRP >24hrs
Inform faculty
07/03/13 257S O MAIYEGUN MD
259. Most common
Dermal melanocytosis
96% of African-American
46% of Hispanic
10% of white children
Common locations are the buttocks, midsacral but
shoulders and extremities may be involved
07/03/13 259S O MAIYEGUN MD
263. Sebaceous retention cyst
These small, whitish-yellow
papules are found close to
the skin surface, being
particularly common around
the eyes and midface
Reassurance
07/03/13 263S O MAIYEGUN MD
264. Note the yellowish
papules on the nose of
this infant
Sebaceous gland
hyperplasia
Reassurance
07/03/13 264S O MAIYEGUN MD
265. Caused by sweat retention
Characterized by a vesicular eruption with
subsequent maceration and obstruction of the
eccrine ducts
Keratinous plugging of eccrine ducts and the
escape of eccrine sweat into the skin below the
level of obstruction
266. Miliaria crystallina (sudamina): clear superficial
pinpoint vesicles without an inflammatory areola
Miliaria rubra (prickly heat): deeper level of sweat
gland obstruction, and characterized by small
discrete erythematous papules, vesicles, or
papulovesicles
267. Sweat rash and heat
rash :ducts connecting
sweat glands with the
surface of the skin get
blocked & perspiration
gets trapped under the
skin
Reassurance
07/03/13S O MAIYEGUN MD 267
273. Pearls (sebaceous retention cyst) may be found in a
variety of locations in the newborn
The tip of the foreskin is another relatively common
location
The pearl is a small, firm, white nodule that contains
keratin
It will spontaneously exfoliate and resolve with time
It is a normal finding and is not a contraindication to
circumcision, if desired
07/03/13 273S O MAIYEGUN MD
274. Numerous yellow papules
and pustules are surrounded
by large intensely
erythematous rings
50% of full terms
Rare in preterms
Eosinophils + (Wright stain)
Reassurance
07/03/13 274S O MAIYEGUN MD
275. Note the reticulated bluish-
purple mottling of this infant's
thigh
-Vasomotor instability
-Normal
-Poor perfusion, hypovolumia
-septic shock
-Cornelia de Lange
syndrome
-Down syndrome
07/03/13 275S O MAIYEGUN MD
276. Nevus flammeus
neonatorum: a typical light
red splotchy area is seen at
the nape of the neck and
forehead
Dilated superficial capillaries
Reassurance
07/03/13 276S O MAIYEGUN MD
277. Characteristic purplish-red
lesion covering nearly half of
face
Capillary malformation
If neurologic signs MRI
brain and Ophthalmology
consult
Reassurance
07/03/13 277S O MAIYEGUN MD
278. Multiple soft, red, raised
lesions dot the back and
arms
Reassurance
07/03/13 278S O MAIYEGUN MD
279. The vessels that make
up this large, partially
compressible lesion are
deep beneath the skin
surface but still impart
a bluish hue to the
overlying skin. Note the
indistinctness of the
margins.
MRI chest
280. The hemangioma on
this child's nasal
bridge has both
superficial and deep
components.
MRI brain
281. A, Two small nevi with
differing degrees of
hyperpigmentation
B, The giant nevus
covering the lower back
and buttocks, is uniformly
pigmented and has
smaller satellite nevi.
MRI spine
282. Red papules and pustules
are present over the nose
and cheeks
07/03/13 282S O MAIYEGUN MD
283. Present at birth
Pustules without surrounding
erythema
Ruptured pustules with
hyperpigmented macules
with a rim of surrounding
scale
Occur in 5% African-
American, rare in other racial
groups
Pustules contain PMN’s
07/03/13 283S O MAIYEGUN MD
287. While the blister created by the infant sucking on his
extremity in the womb may still be intact at the time of
delivery
Often it appears as a flat, scabbed, healing area (as
shown)
Sucking blisters are solitary lesions that occur only in
areas accessible to the infant's mouth
They are benign and resolve spontaneously
The appearance and location of the lesion is usually
sufficient for diagnosis, but if the infant is observed
sucking on the affected area, the diagnosis is certain
07/03/13 287S O MAIYEGUN MD
288. Breakage of small vessels
during the pressure of
delivery
Reassurance
307. http://newborns.stanford.edu/PhotoGallery
Atlas of Pediatric Physical Diagnosis : Basil J.
Zitelli MD, Holly W. Davis MD
Nelson Textbook of Pediatrics
The Atlas of Emergency Medicine .Chapter 15.
Child Abuse
Lynne Uhring, MD, FAAP Frequently Asked
Questions About Newborn Babies
07/03/13 307S O MAIYEGUN MD
308. Carrie L. Byington and Carol J. Baker: CDC
updates guidelines on prevention of perinatal
GBS ,AAP News, Dec 2012
Revised previous edition by Dr. N Singh
Guidelines for Perinatal Care, 7th Edition Jointly
developed by the AAP Committee on Fetus and
Newborn and ACOG Committee on Obstetric
Practice
07/03/13S O MAIYEGUN MD 308
309. Red Book: 2012 Report of the Committee on
Infectious Diseases, 29th Edition
Lynne Uhring, MD, FAAP Frequently Asked
Questions About Newborn Babies
Neonatology Management, procedure, on-call
problems, diseases and drugs: 6th
Edition,
Gomella TL
07/03/13S O MAIYEGUN MD 309
Editor's Notes
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Mongolian spots appear on the buttocks, back, and upper arms of many infants.