SlideShare a Scribd company logo
1 of 309
Author: Sitratullah O Maiyegun MD
Editors: Namrata Singh MD
Maria Villanos MD
Jesus Peinado MD
Ashish Loomba MD
Well baby Nursery Director: Carmen
Prieto MD
07/03/13 1S O MAIYEGUN MD
 The guidelines do not indicate an exclusive
course of treatment or serve as a standard of
medical care
 Appropriate management can be modified
according to individual circumstances
 Please apply evidence based medicine as
appropriate
07/03/13 2S O MAIYEGUN MD
 Evaluate well newborns with history, physical
exam and routine screening procedures, and
provide preventive counseling and intervention
as indicated
 Manage breast and formula feeding in the
newborn period
 Evaluate and manage common conditions and
infections in the normal newborn
07/03/13S O MAIYEGUN MD 3
 Recognize and manage jaundice in the newborn
period
 Provide anticipatory counseling at nursery
discharge that relates to newborn behavior,
family adjustment, injury prevention, and access
to medical services
07/03/13S O MAIYEGUN MD 4
 Wash hands before and after examining any
infant
 All babies must be examined within 24 hours of
birth
 All admission orders (entered by nurses) must
be signed
 Maternal prenatal lab results and GBS status,
and mother and infant’s blood types
 HIV, RPR and Hep B status must be updated
within 12 hours of delivery
  
07/03/13S O MAIYEGUN MD 5
 Admission and discharge diagnoses to be
documented with problem lists
 Update maternal labs prior to discharges
 Any abnormal results reported to the intern must
be reported to the senior and/or faculty
07/03/13S O MAIYEGUN MD 6
 Birth weight < 2250 gms
 Gestational age < 35 wks
 Apgar score of <5 at 5 mins
 Prolonged period of abnormal transition (more
than 4 hrs )
 Initial Se. Glucose <30 mg% (after ISTAT)
 Maternal chorio detected in L&D
 Initial rectal temp 102 F or more
 Unstable baby in L&D or OR
07/03/13 7S O MAIYEGUN MD
 All babies will be placed skin-to-skin with mom
for breastfeeding for as long as they are stable
 Nursing procedures and further assessment will
be done while with mom
 Babies will be transferred to room with mom
from L&D
07/03/13S O MAIYEGUN MD 8
 Babies of diabetics and moms on magnesium
will also be placed skin-to-skin unless otherwise
symptomatic or per pediatrician order
 After skin-to-skin they will go to the NBN for
further assessment or stay with mom if mom is
stable
 Stable C/S babies stay with the relatives in
OR /L&D till mom is able to handle the baby
07/03/13S O MAIYEGUN MD 9
 Maternal history of diabetes, Fever
 PROM >18hours (CDC, AAP)
 <37wks
 Weight ≥3800 gms and ≥2500gms
 LGA >90th
percentile or SGA/IUGR < 10th
percentile for weight
07/03/13S O MAIYEGUN MD 10
 Blood glucose within 30mins-1hour of admission
in high risk babies
 Peripheral hematocrit: in high risk babies
 Eye prophylaxis with 0.5% erythromycin
ophthalmic ointment
 Vitamin K 1mg IM X1
 Hepatitis B vaccine X1( after consent)
 Cord blood studies if mother is O+ or Rh (-)
07/03/13 11S O MAIYEGUN MD
 Radiant warmer in the nursery until stable to
transfer to mom’s room
 If needed , formula feeds need to be prescribed
( Baby-friendly policy)
 Normal delivery24hours observation if all
discharge criteria fulfilled
 If risk factors  48hours
 C/S delivery  observe for 48hrs
07/03/13 12S O MAIYEGUN MD
 Breastfed and formula fed infants should be
supplemented with 400 IU/day of vitamin D
beginning in the first few days of life
 Supplementation should be continued unless
the infant is weaned to at least 1 L/day vitamin
D–fortified formula (1 or 2 months)
 1liter of regular infant formula(406 IU of Vitamin
D)
07/03/13S O MAIYEGUN MD 13
 Newborn hearing screen before discharge
 If failed Algo X2Refer for BAER
 Newborn screen at 24hrs of life
 Jaundice meter reading upon admission and q
shift until discharge
07/03/13 14S O MAIYEGUN MD
 History
 Adequate prenatal care≥ 4 visits
 Maternal age > 17years
 No maternal drug use
 Mother not A1or A2 diabetic
 Mother not GBS+ or Chlamydia +
 Mother not RPR+, HIV +, HepB/C +
07/03/13 15S O MAIYEGUN MD
 Delivery
 Vaginal delivery in the hospital
 Rupture of Membranes < 18hours (CDC)
 No maternal temperature >101 or concern
regarding chorioamnionitis
 Apgar score at 5minutes at least 7
07/03/13 16S O MAIYEGUN MD
 Examination
 Gestational age of at least 37weeks
 Baby is not on 24-hour glucose series (LGA,
SGA or initial hypoglycemia)
 No physical findings that requires further
monitoring
 Vital signs are documented as being within
normalranges and stable for the last 12 hours
preceding discharge
07/03/13 17S O MAIYEGUN MD
 No vital signs abnomalities: No Temp instability,
RR<60, HR 100-160, axillary temperature of
36.5°C to 37.4°C (97.7°F to 99.3°F)
 No Jaundice in the first 24hrs
 The clinical significance of jaundice, if present
before discharge,has been determined, and
appropriate managementand/or follow-upplans
have been put in place
07/03/13S O MAIYEGUN MD 18
 No Jaundice in the first 24hrs
 The clinical significance of jaundice, if present
before discharge,has been determined, and
appropriate managementand/or follow-upplans
have been put in place
07/03/13S O MAIYEGUN MD 19
 No history of poor feeding or emesis
 Able to coordinate sucking,swallowing, and
breathing while feeding
 Normal voiding and stooling pattern
07/03/13 20S O MAIYEGUN MD
 Labs
 No Glucose issues during the first 24hrs
 Bilirubin in the normal range as per risks
 Maternal RPR, HIV, HBsAG status known
 If Rubella non-immune inform OB resident to
make sure mom is vaccinated PTD
 No ABO setup, baby is Coombs negative
 Algo hearing test done (otoacoustic emission)
done
07/03/13S O MAIYEGUN MD 21
 Psychosocial
 At least 2 successful feedings without the help
of nurses (lactation consult if needed)
 Good maternal-baby bonding, no maternal
depression
 No nursing concerns
07/03/13 22S O MAIYEGUN MD
◦ Cord, skin, and genitalcare for infant
◦ Ability to recognize signs of illness and
common infant problems,particularly jaundice
◦ Proper infantsafety (proper use of a car safety
seat andsupine positioningfor sleeping)
07/03/13S O MAIYEGUN MD 23
 Teenage mothers <17 yrs with or without
prenatal care
 Teenage mothers <17 yrs without a family or
support system in place or other specified
problems (i.e. depression, lack of planning,
bonding)
07/03/13 24S O MAIYEGUN MD
 Mothers with substance abuse (present +
screen or previous)
 Mother with previous hx of post-partum
depression
 Discharge against medical advice
07/03/13S O MAIYEGUN MD 25
 Early discharges < 48 hours follow-up within 1
to 2 days or 72 hours (earlier visit not possible)
 If no risk factors, clinically well d/c after 24
hours
 If risk factors are present, clinically not well
appearing, required limited evaluation d/c
after 48 hours
07/03/13S O MAIYEGUN MD 26
A
07/03/13S O MAIYEGUN MD 27
 Problem-
◦ Any deviation from completely normal external
male or female genitalia
 Clitoral enlargement (> 1.0 cm)
 Labioscrotal fusion of any degree
 Hypospadias (penoscrotal, scrotal or perineal
)
07/03/13 28S O MAIYEGUN MD
 Any degree of hypospadias with unilateral or
bilateral cryptorchidism
 Micropenis (stretched length < 2.5 cm)
 Bilateral cryptorchidism ( with other
anomalies )
07/03/13S O MAIYEGUN MD 29
30
 Please do not include prominent labia minora
in a preterm
 Check the gestational age!!!!!!!
3/2/2011S O MAIYEGUN MD 07/03/13 30S O MAIYEGUN MD
 First degree (glandular): urethral meatus opens
on the underside of the glans penis in about 50–
75% of cases
 Second degree(Midshaft) :when the urethra
opens on the shaft
 Third degree (penoscrotal and perineal): when
the urethra opens on the perineum) occur in up
to 20 and 30% of cases respectively
07/03/13S O MAIYEGUN MD 31
07/03/13 32S O MAIYEGUN MD
07/03/13 33S O MAIYEGUN MD
 Severe degrees are more likely to be associated
with chordee
 The phallus is incompletely separated from the
perineum or is still tethered downwards by
connective tissue, or with undescended testes
(cryptorchidism)
07/03/13S O MAIYEGUN MD 34
35
 Hypospadias ( 1st
and 2nd
degree) with
palpable testicles
 Observe and referral to urologist outpt
 No need for US kidneys (develops from
genital tubercles)
 Advice against circumcision (prepuce for
repair)
3/2/2011S O MAIYEGUN MD 07/03/13 35S O MAIYEGUN MD
07/03/13S O MAIYEGUN MD 36
CHORDEE
 Plan-
 No gender assignment until after endocrine
consult
◦ As soon as possible after birth
 U/S abdomen ( uterus, testes, adrenals)
 Karyotype
 17-OH progesterone
 Electrolytes BMP ( virilization )
07/03/13 37S O MAIYEGUN MD
 LH, FSH, Testostorone, dihydrotestostrone,
DHT,
 Peds endo consult stat !!!!
 Parent education and counseling !!!!
07/03/13S O MAIYEGUN MD 38
 Problem-
◦ Initial HCT of <40 mg% (spun Hct)
◦ Pale newborn
 Plan-
◦ Do PE & check for symptoms ( splenomegaly,
tachypnea, tachycardia, shock, CHF, murmur )
—if present consult attending
07/03/13 39S O MAIYEGUN MD
 Plan-
◦ Check maternal history
 Severe prenatal anemia
 Perinatal blood loss
 3rd
trimester bleeding
 Maternal blood type & antibody screen
 Abruptio placenta or placenta previa
07/03/13 40S O MAIYEGUN MD
◦ Check birth history
 Asphyxia & Apgar scores
 Delivery method & special circumstances
 Plan-
◦ Lab w/u-
 CBC & peripheral smear
 Retics count, fractionated bili
 Blood type & Coombs
07/03/13S O MAIYEGUN MD 41
 Plan-
 Maternal Kleihauer Betke test (request OB
resident to order)
 Repeat HCT in 12-24 hrs – if decreasing
notify attending ( may need head &/or
abdominal US- liver/adrenal hemorrhage)
07/03/13 42S O MAIYEGUN MD
B
07/03/13S O MAIYEGUN MD 43
 Problem-
◦ Blood streaked diaper with normal stool
 Plan-
◦ Check for-
◦ Clinical activity
 Small laceration/fissure or area of irritation in
anal area
 Abdominal distention
 Other symptoms (poor feeding , vomiting
etc.)
07/03/13 44S O MAIYEGUN MD
 Plan-
◦ If no fissure-
 Stool for occult blood
 Stool for culture, WBC and rotavirus
 Stool for reducing substance
 **Apt test (send-out) take a while to get result
 If maternal blood – f/u
 If fetal blood – discuss with attending
 Make sure Vit K has been given
07/03/13 45S O MAIYEGUN MD
 CBC with diff :
◦ inflammatory response
◦ thrombocytopenia
◦ anemia
 If abdominal distention
 Stat KUB
 Stat CBC & CRP
 Discuss with attending
07/03/13S O MAIYEGUN MD 46
 Problem-
◦ Infant not moving arm ; arm & held limply
extended to the side with hand flexed
◦ Erb-Duchenne palsy (C5 - C6)
◦ Klumpke’ s paralysis ( C7-8 , T1)
 Plan –
◦ Examine infant-
 Clavicular crepitus
 Presence of grasp ( absent in Klumpke’s)
 Assoc. resp distress ( Erb’s) ; Horners synd
( Klumpke’s)
07/03/13 47S O MAIYEGUN MD
07/03/13 48S O MAIYEGUN MD
 Plan-
◦ Cxr with clavicles
 If clavicle fractured –immobilize arm
 F/u outpt with Orthopedics
◦ Physical Tx consult as outpt
◦ Neurology consult as outpt if severe Erb’s
palsy
07/03/13 49S O MAIYEGUN MD
07/03/13 50S O MAIYEGUN MD
 HR=85-160bpm (0-24hr) 100-175bpm(1-7days)
or > 2SD above the mean for age, asleep or
awake
 HR persistently < 80-100/min(awake),<70-
90/min(asleep) and/or dropped beats
 Dropped or skipped beats
07/03/13SOMAIYEGUN MD 5107/03/13 51S O MAIYEGUN MD
 Plans:
 Maternal Hx of SLE
 Ionized Ca with BMP(K+)
 EKG and CXR (pneumothorax/heart shape)
 Cardiac consult
 Echo after discussion with the attending
07/03/13SOMAIYEGUN MD 5207/03/13 52S O MAIYEGUN MD
C
07/03/13SOMAIYEGUN MD 5307/03/13 53S O MAIYEGUN MD
54
 Molding of the head
 Crosses the suture lines
 Subcutaneous soft tissue swelling
 Poorly defined margins
 Usually resolves over the first few days
 Observation
SOMAIYEGUN MD07/03/13 54S O MAIYEGUN MD
Subperiosteal hemorrhage
◦Unilateral or bilateral, most commonly over
parietal bone, rarely the occipital bone
◦Firm swelling or fluctuant
◦Limited by suture lines/ does not cross the
suture lines
07/03/13 55S O MAIYEGUN MD
 Plan-
◦ Obtain delivery history: SVD, forceps and
vacuum
◦ Check for jaundice q 12hrs (J-meter)
◦ Discuss with mother- reassurance
 May be felt till 3 mos of age & may calcify
07/03/13S O MAIYEGUN MD 56
07/03/13 57S O MAIYEGUN MD
07/03/13 58S O MAIYEGUN MD
07/03/13 59S O MAIYEGUN MD
07/03/13 60S O MAIYEGUN MD
 If large or bilateral, CNS signs, difficult delivery,
depressed skull fracture AP & Lat skull X-
Rays or CT head( discuss)
 If Hct dropped rapidly inform attending
 US head or CT head to r/o ICH/IVH
◦ PT/PTT, CBC (Immune
thrombocytopenia)
◦ If signs of shock IMCN
07/03/13 61S O MAIYEGUN MD
 There is increased risk of intracranial
hemorrhage among infants delivered by vacuum
extraction or forceps or unassisted vaginal
deliveries (or prolonged labor )
 ICH: subdural or cerebral hemorrhage,
intraventricular hemorrhage, subarachnoid
hemorrhage
07/03/13 62S O MAIYEGUN MD
 Problem –
◦ Shoulder dystocia @ birth
◦ Tenderness , swelling over clavicle
◦ Crepitus over clavicle
◦ Decreased movement of arm
 Plan—
◦ X-rays of clavicle
07/03/13 63S O MAIYEGUN MD
 It may be asymptomatic
 Generally, there is no treatment other than lifting
the child gently to prevent discomfort
 The arm on the affected side may be
immobilized by pinning the sleeve to the
clothes (Swaddle / immobilize)
 Orthopedic referral as out-patient, if severe
as in-patient ( discuss with attending)
07/03/13S O MAIYEGUN MD 64
07/03/13S O MAIYEGUN MD 65
 DD: partial dislocation of the elbow, Erb palsy,
fractured humerus
 Reassure mother and inform about subsequent
callus formation
 Full recovery usually occurs without treatment
07/03/13S O MAIYEGUN MD 66
 Problem-
◦ Abnormal buccal cavity
◦ Maybe unilateral , bilateral or midline
◦ Maybe mild , severe or partial
◦ Maybe submucosal with bifid uvula
 Plan-
◦ Obtain fam hx ,prenatal hx (meds)
◦ If midline  head U/S to r/o
holoprosencephaly
07/03/13 67S O MAIYEGUN MD
07/03/13 68S O MAIYEGUN MD
 Plan-
◦ Assess feeding
 Special nipple- Haberman nipple
 No bottle propping
 Feed in upright position
 Occupation therapy (OT) consult
 Plastic surgery consult as outpatient
 Genetics consult as outpatient if indicated
07/03/13 69S O MAIYEGUN MD
 Haberman nipple for feeding
07/03/13 70S O MAIYEGUN MD
 Problem-fixed or flexible (positional)
◦ Forefoot in fixed adduction
◦ Calcaneal tendon is shortened
◦ Foot is inverted with plantar flexion
◦ Inability to correct itself by stroking the outside
& inside of foot (fixed)
 Plan-if fixed
◦ Check hips
◦ Ortho consult as in-patient (X-ray, stretching
and serial casting)
◦ Discuss with mother
07/03/13 71S O MAIYEGUN MD
 If flexible (positional) , reassurance and passive
stretching by mother q prn
 Any orthopedic abnormalities, discuss with
attending prior to ortho consult
07/03/13 72S O MAIYEGUN MD
07/03/13 73S O MAIYEGUN MD
 Eye prophylaxis with 0.5% erythromycin
ophthalmic ointment
 It is not effective in preventing neonatal
chlamydial conjunctivitis or extraocular infection
 Effective for prevention of gonococcal
ophthalmia
07/03/13 74S O MAIYEGUN MD
 Problem-
◦ Newborn with eye discharge
◦ Can be unilateral or bilateral
◦ Possible periorbital edema
◦ Eyelids may be erythematous or appear glued
shut
07/03/13 75S O MAIYEGUN MD
 Plan-
◦ Maternal hx of GC , Chlamydia , Herpes
◦ Delivery hx –( Erthromycin ointment application
, maternal vaginal discharge , PROM)
◦ Evaluate timing of onset , amount ,color,
consistency, tendency to return
◦ Plans;
 Gram stain and culture
07/03/13 76S O MAIYEGUN MD
 Plan-
◦ If Gram stain positive for bacteria or PMN’s ,
discuss with attending
◦ Cleanse eyes with sterile water
 Note—
◦ Chemical conjunctivitis—
 Develops within hours after birth & resolves
in 36-48 hours
 Gram stain negative but PMN’s are present
07/03/13 77S O MAIYEGUN MD
◦ GC conjunctivitis–
 Presents usually 1-4 days after birth
 Can present within a few hours after birth
 Lid edema , copious purulent exudate ,
chemosis , clouding of the cornea
07/03/13 78S O MAIYEGUN MD
Gm stain  PMN’s & intracellular Gm negative
diplococci
Tx – Inform attending for transfer to IMCN for
Ceftriaxone and workup for sepsis
Reportable to Department of Health within
72hours
07/03/13S O MAIYEGUN MD 79
 Ceftriaxone (25-50 mg/kg, intravenously or
intramuscularly, not to exceed 125 mg) given x 1
 Cefotaxime x1 (100mg/kg IV or IM) is
recommended for infants with hyperbilirubinemia
 Infants with gonococcal ophthalmia should
receive eye irrigations with saline solution
immediately and at frequent intervals until the
discharge is eliminated
07/03/13 80S O MAIYEGUN MD
 Topical antimicrobial treatment alone is
inadequate and is unnecessary when
recommended systemic antimicrobial treatment
is given
07/03/13 81S O MAIYEGUN MD
 Hospitalized and evaluated for disseminated
infection (sepsis, arthritis, meningitis)
 Recommended therapy for arthritis and
septicemia is ceftriaxone or cefotaxime for 7
days, if meningitis is document treatment should
be continued for a total of 10 to 14 days
07/03/13S O MAIYEGUN MD 82
◦ If late onset > 1st
24 hours of life or suspected
causes other than reaction to eye prophylaxis
 Gram stain & culture
◦ Chlamydia conjunctivitis—
 Presents 5-14 days after birth
 Purulent discharge, eyelid edema &
conjunctival inflammation
07/03/13S O MAIYEGUN MD 83
 Conjunctival scraping for Chlamydia:
Infectious disease consult
 Reportable to Department of Health within
72hours
07/03/13S O MAIYEGUN MD 84
If mom is Chlamydia positive and with or
without treatment
Baby is asymptomatic  no treatment FU
in out-pt for signs of infection
 Prompt treatment of mother and her sexual
partner(s)
07/03/13S O MAIYEGUN MD 85
 Oral azithromycin for 5 days or erythromycin
base or ethylsuccinate for 14 days +
erythromycin eye ointment
 If unstable and severe respiratory  IV
erythromycin after evaluation for sepsis in IMCN
 Infantile hypertrophic pyloric stenosis (IHPS) in
< 6weeks (erythromycin)
07/03/13 86S O MAIYEGUN MD
 Problem—
◦ Infant with soft or ping-pong skull
◦ Usually over temporo-parietal region & along
suture lines
◦ Causes-
 Hydrocephalus ,OI ,syphilis, rickets ,
hypervitaminosis A , normal variation (sagittal
suture craniotabes in premies)
07/03/13 87S O MAIYEGUN MD
 Plan—
◦ Maternal Hx– infections , medications , family
history
◦ Transilluminate skull
◦ Head US & skull X-rays – if needed
◦ Check maternal RPR – if positive follow
syphilis protocol
07/03/13 88S O MAIYEGUN MD
D
07/03/13S O MAIYEGUN MD 89
90
 Problem-
◦ Hip “clunk”
◦ Positive Barlow or Ortolani sign
◦ Unequal thigh/gluteal creases or leg lengths
◦ Strong family history
◦ Breech presentation
SOMAIYEGUN MD
07/03/13 90S O MAIYEGUN MD
 Plan-
◦ If “click” present  re-examine @ D/C
◦ If “click” & + strong family history Ortho
consult
◦ If “clunk” present Ortho consult
◦ U/S hip if needed, will be ordered or advised
by orthopedics
◦ Discuss with mother
◦ FU with PCP
◦ Only ClickRe-check hips in 2 weeks(AAP)
SOMAIYEGUN MD07/03/13 91S O MAIYEGUN MD
 Breech with abnormal click/clunk prior to
discharge Ortho consult or otherwise U/S hip at
4-6 weeks of age and/or radiographic imaging at
4-6 mos (AAP)
 US hip screening of all breech newborns will not
eliminate the possibility of later acetabular
dysplasia (AAP)
07/03/13 92S O MAIYEGUN MD
 Problem—
◦ 2 abnormal stools in an 8 hour period
◦ Numerous large watery , foul smelling stools
with blood , mucous
 Plan—
◦ Examine baby & review vitals
◦ Look at stool
◦ Send stool for reducing substances,
leucocytes, RBC & culture, rotavirus
07/03/13 93S O MAIYEGUN MD
94
 If reducing substance positive(+)  switch to
soy based formula/ lactose free milk
◦ If stool is watery++ sent stool for electrolytes
◦ BMP
◦ Suspect chloride diarrhea in mom with hx of
polyhydramnios
3/2/2011S O MAIYEGUN MD 07/03/13 94S O MAIYEGUN MD
 Plan—
◦ If baby looks sick , abnormal vitals , abdominal
distention get KUB stat , CBC , CRP, BMP
◦ Inform attending
◦ Discuss normal variations in stooling patterns
with mother
07/03/13 95S O MAIYEGUN MD
 Breast fed stools-frequent, without form, may
be mucousy; affected by maternal diet ( fruit ,
laxatives ,medications)
 If starvation present may be frequent , small
quantity, dark green
 Stools can be less frequent & pasty
07/03/13S O MAIYEGUN MD 96
◦ Discuss normal variations in stooling patterns
with mother
 Breast fed stools-frequent, without form ,may
be mucousy; affected by maternal diet ( fruit ,
laxatives ,medications)
 If starvation present may be frequent , small
quantity, dark green
 Stools can be less frequent & pasty
07/03/13S O MAIYEGUN MD 97
07/03/13 98S O MAIYEGUN MD
 3-8% of NB
 The possibility of occult spinal dysraphism
(OSD) is more likely if above the gluteal cleft
(truly sacral in location) because they are more
likely to be contiguous with the dura
 Within the gluteal fold: less likely to be
contiguous with the dura and are much more
likely to be a normal variant
07/03/13 99S O MAIYEGUN MD
 Simple or low risk :
 Position – within the gluteal fold or coccygeal
position
 Single dimple
 < 5 mm diameter
 Base of dimple is visible
07/03/13 100S O MAIYEGUN MD
 Dimple is oriented straight down (i.e. caudal) not
cephalically (i.e. toward the head)
 No other dermal abnormalities or masses
 Distance < 2.5 cm from anus
 Normal neurological examination
07/03/13S O MAIYEGUN MD 101
 Difficult to clearly distinguish all variations
consider the individual circumstances
 Plan: U/S spine
3/2/2011 102S O MAIYEGUN MD 07/03/13 102S O MAIYEGUN MD
 Midline / vertebra appearance of significant
tuft of hair ,hemangioma or nevus
 Plan: U/S spine
07/03/13 103S O MAIYEGUN MD
 Discharge diagnosis is very important
 Make an assessment regarding what
observation and treatment the infant needs and
discuss findings with the parents
 Explain to the parent(s) of the possible
consequences for their infant if they leave e.g
sepsis, jaundice
 Explain the need for FU in 1 or 2 days and ER
warnings
 Consult with the social worker (SW)
07/03/13 104S O MAIYEGUN MD
 If medical diagnosis or concerns exist which
may result in immediate harm to the infant
 Remind parent(s) that their action is contrary to
the welfare of their infant and that Department
for Child Protective Services (CPS) will be
notified
 Child can be kept in the holding nursery if
mother wants to go home
07/03/13 105S O MAIYEGUN MD
 Consult with the social worker (SW)
 They will make an assessment and consult with
CPS or Crisis Care (after hours/weekends) as
necessary
 CPS hold statutory powers and have the
authority under the Children and Community
Services Act 2004 to protect the welfare, care
and protection of children
07/03/13 106S O MAIYEGUN MD
07/03/13 107S O MAIYEGUN MD
 Infant with features of Down syndrome
◦ Talk to the family (mom)
◦ No d/c prior to 48 hrs of age
◦ Evaluate feeding / vomiting (duodenal atresia)
◦ Glucose series (hypoglycemia)
◦ CBC with diff & platelets(polycythemia,
leukemoid reaction or leukemia)
◦ Ensure good follow-up
07/03/13 108S O MAIYEGUN MD
 Karyotype (with informed consent)
◦ Maternal and family history
◦ Echocardiogram prior to discharge
◦ Cardiac consult as needed
◦ Genetics consult as out-patient
07/03/13 109S O MAIYEGUN MD
E
07/03/13S O MAIYEGUN MD 110
 Problem—
◦ Grossly abnormal ears
◦ Significant low set and posteriorly rotated ears
◦ Incomplete auricle
◦ No visible ear (anotia)
◦ Multiple significant ear tags (pre-auricular tags)
◦ Pre-auricular sinus/pit with a blind end is not
included
07/03/13 111S O MAIYEGUN MD
07/03/13 112S O MAIYEGUN MD
07/03/13 113S O MAIYEGUN MD
 Plan—
◦ Strong family history of similar defects
◦ Hearing test (ALGO 2)  if failed schedule for
BAER test
◦ Renal US to r/o abnormalities after discussing
with faculty
◦ Look for other dysmorphic features and
associations
07/03/13 114S O MAIYEGUN MD
 C coloboma
 H congenital heart defects
 A choanal atresia
 R retardation of growth and development/ CNS
 G genitourinary anomalies
 E ear and/or auditory anomalies
07/03/13 115S O MAIYEGUN MD
 Newborn with copious oral secretions and
episodes of coughing, choking, and cyanosis
 Hx of pregnancy complicated by polyhydramnios
 Plans: place an orogastric suction catheter and
obtain a chest radiograph
07/03/13 116S O MAIYEGUN MD
 VACTERL association
 V Vertebral or Ventriculoseptal defects
 A Anal atresia
 C Cardiac anomalies
 T/E Tracheoesophageal fistula/ esophageal
atresia
 R Radial dysplasia / Renal anomaly
 L limbs
3/2/2011 117S O MAIYEGUN MD 07/03/13 117S O MAIYEGUN MD
F
3/2/2011 118S O MAIYEGUN MD 07/03/13 118S O MAIYEGUN MD
 Problem—
◦ Large anterior fontanel (>5 x 5 cm)
with/without large posterior fontanel
( > 2 cm)
◦ Open metopic suture
◦ Open coronal suture
 Plan—
 Check HC yourself ; neurologic exam
 T4 & TSH ; head sono ; discuss with
attending
07/03/13 119S O MAIYEGUN MD
07/03/13 120S O MAIYEGUN MD
07/03/13 121S O MAIYEGUN MD
G
07/03/13S O MAIYEGUN MD 122
◦ GBS+ mother with 1 dose of intrapartum abx
< 4hrs PTD  CBC and CRP at 24 hrs
◦ GBS+ mother with at least 1 dose of
intrapartun abx > 4hrs PTD asymptomatic
observe for 48hrs
◦ No discharge prior to 48 hrs of age
 If baby is unstable  CBC/+ CRP (if
>24hr) stat ± transfer to IMCN as
appropriate
07/03/13 123S O MAIYEGUN MD
◦ PROM >18hrs (+ intrapartum abx given to
mum), if stable CBC & CRP at 24 hrs and
re-evaluate
◦ PROM >18hrs (no intrapartum abx given to
mum) CBC at birth and CBC & CRP at 24
hrs and re-evaluate
◦ No discharge prior to 48 hrs of age
07/03/13 124S O MAIYEGUN MD
◦ GBS (+)mum, good PNC, term ≥37wks, SVD
◦ Adequate intrapartum antibiotic prophylaxis
(IAP) given
◦ Asymptomatic baby
◦ Mom is able to comply with home instruction for
observation
◦ Can be discharged home after 24hrs if other
discharge criteria are met
◦ If discharge criteria are not met  observe for
48hrs
07/03/13 125S O MAIYEGUN MD
◦ Intrapartum antibiotic prophylaxis (IAP)
◦ Adequate if penicillin, ampicillin or cefazolin is
given at the proper doses for four or more
hours prior to delivery
◦ Duration of IAP shorter than four hours and all
other antimicrobial regimens,
 clindamycin
 Vancomycin
◦ are considered as inadequate because no data
regarding efficacy are available
07/03/13 126S O MAIYEGUN MD
 Penicillin and ampicillin rapidlyachieve
therapeutic levels in the fetal circulation and
requirethree hours to achieve therapeutic levels
in amniotic fluid
 Cefazolin has similar pharmacokinetics and is
the preferredagent for IAP in penicillin allergic
women with no history ofanaphylaxis,
angioedema, respiratory distress or urticaria
07/03/13 127S O MAIYEGUN MD
 Problem:
◦ No documented PNC or GBS unknown
◦ Prenatal care at lay midwife maternity center
◦ Less than 4 visits starting later than 28th
week
of gestation
 Plan—
◦ Check perinatally drawn maternal labs and
please document prior to D/C
07/03/13 128S O MAIYEGUN MD
 If baby is stable: NO screening with CBC and
CRP at 24 hours
 Observe for 48hour in the hospital
 If baby symptomatic at anytime
<24hours CBC stat ± transfer to IMCN
as appropriate
 If symptomatic > 24hours CBC and
CRP ± transfer to IMCN as appropriate
3/2/2011 129S O MAIYEGUN MD 07/03/13 129S O MAIYEGUN MD
◦ PROM >18hrs (+ intrapartum abx given to
mom), if stable CBC & CRP at 24 hrs and
re-evaluate
◦ PROM >18hrs (no intrapartum abx given to
mom) CBC at birth and CBC & CRP at 24
hrs and re-evaluate
◦ GBS (–)negative in the hospital and NPC 
48hrs observation
◦ No discharge prior to 48 hrs of age
3/2/2011 130S O MAIYEGUN MD 07/03/13 130S O MAIYEGUN MD
◦ Any symptoms  CBC stat or CBC and CRP if
>24hrs or transfer to IMCN as appropriate
◦ If labs are grossly abnormal CRP>20 x 2 or
CRP >40 X1, WCC>30 or <5, even if clinically
stable, discuss with attending for possible
transfer to IMCN
**48-hour CBC and CRP will be ordered after
24-hour lab is reviewed
07/03/13 131S O MAIYEGUN MD
 Problem—
◦ Maternal h/o GC during pregnancy
 Plan—
◦ Maternal h/o tx & documentation of cure
◦ If inadequate or no documented test of cure 
Ceftriaxone 125 mg I/M x 1
◦ No discharge prior to 48hrs
07/03/13 132S O MAIYEGUN MD
H
07/03/13S O MAIYEGUN MD 133
 Problem—
◦ Maternal h/o hepatitis
◦ Mother known HBsAg carrier
◦ Mother @ high risk for being a Hep B carrier
( known or suspect IV drug use , mother from
endemic region)
07/03/13 134S O MAIYEGUN MD
 Plan—
◦ Verify maternal HBsAg status
◦ If mother positive
◦ Hep B Ig (0.5 cc I/M) within 12 hrs of birth
 Hepatitis B vaccine ( 0.5 cc I/M) concurrently
@ different site
 Breastfeeding is not C/I
 ID consult as outpt
07/03/13 135S O MAIYEGUN MD
 Plan—
◦ Infants delivered to mothers who are jaundiced
,h/o hepatitis of unknown etiology or who are
in a high risk group & have not been screened
—
 Hep B vaccine (0.5 cc I/M ) within 12 hrs of
birth
 Verify mothers HBsAg status ; make sure it is
drawn. If positive give HBIG
07/03/13 136S O MAIYEGUN MD
 Plan—
◦ Mother is Hepatitis C+(anti-HCV-positive )
 Order Hep C Ag on baby : (Ig) G antibody
enzyme immunoassays for HCV and NAA
tests to detect HCV RNA
 Assays for IgM to detect early or
acute infection are not available
 Transmission of HCV by breastfeeding has
not been documented
07/03/13 137S O MAIYEGUN MD
 Not a contraindication to breastfeeding
 Mothers who are HCV positive and choose to
breastfeed should consider abstaining if their
nipples are cracked or bleeding
 F/U with ID as outpt to monitor LFT and anti-
HCV
07/03/13 138S O MAIYEGUN MD
 Problem—
◦ Mother identified as having vaginal herpes
◦ Previous h/o herpes
 Plan—
◦ PE of the baby for rash (vesicles)
◦ Delivery hx-C/S or vaginal ( higher risk)
◦ Instruct mother on care of infant (good hand
washing etc)
07/03/13 139S O MAIYEGUN MD
 Care of infants born vaginally to a mother with
active genital ulcerative lesions. Primary 1st
episode of HSV infection or known recurrent
lesion or status unknown IMCN in isolation
 Care of the infant born via C/S to a mother with
active genital ulcerative lesions (primary,
recurrent or unknown) esp if onset of labor or
ROM > 4hoursIMCN in isolation
07/03/13 140S O MAIYEGUN MD
 Care of the infant born to a mother with a history
of HSV infection and no active lesions at
delivery.
 Neither HSV cultures nor empiric therapy with IV
Acyclovir are indicated
 No isolation necessary
 Care of the infant born by C/S (intact
membrane) and no active lesions at delivery.
 No isolation necessary
07/03/13 141S O MAIYEGUN MD
 A mother with herpes labialis or stomatitis
should wear a disposable surgical mask when
touching her newborn infant until the lesions
have crusted and dried
 She should not kiss or nuzzle her newborn until
lesions have cleared
 Herpetic lesions on other skin sites should be
covered
07/03/13 142S O MAIYEGUN MD
 Problem—
◦ Mother’s HIV is positive
 Plan If complete HIV testing is pending after
birth and the mom is Elisa positive
 Western Blot (WB) still pending then breast
feeding should not be initiated until the WB has
been reported negative
◦ If mother’s WB is (+) 
◦ if baby is stable, can start PO AZT
◦ if unstable IMCN to start on IV AZT
◦ If mothers WB is (-) ,no issues
07/03/13 143S O MAIYEGUN MD
 Plan—
 Detailed hx for risk factors
 Zidovudine (AZT) must be started 6-12
hours after AZT(8mg/kg/day) PO q6hrs X 6
weeks
 Send HIV DNA PCR within the first 48
hours after birth
 Cord blood should not be used
 ID consult as in-patient
07/03/13 144S O MAIYEGUN MD
 Plan—
 If hx inconclusive
 ID consult
 FU on HIV DNA PCR in baby
07/03/13 145S O MAIYEGUN MD
 Maternal history of diabetes, Fever
 PROM >18hours (CDC, AAP)
 <37wks
 Weight ≥3800 gms and ≥2500gms
 LGA >90th
percentile or SGA/IUGR < 10th
percentile for weight
07/03/13S O MAIYEGUN MD 146
 All high risk babies are screened with blood
glucose
 Regardless of gestation a serum glucose <
40 mg/dL is hypoglycemia
 A serum glucose < 45 mg/dl if symptomatic will
be treated as hypoglycemia
07/03/13 147S O MAIYEGUN MD
 Glucose level less than 30mg/dL (<30mg/dL) by
I-STAT will be admitted to EPCH
 Treatment will not be postponed
 Newborns will be formula fed as medically
indicated for hypoglycemia less than 30mg/dl
prior to admission to EPCH at 10ml/kg
07/03/13 148S O MAIYEGUN MD
 Pre-prandial serum glucose q 3 hours during the
first 24 hours of life
 Glucometer and confirmed by I-STAT if level is
less than 40mg/dl
07/03/13 149S O MAIYEGUN MD
 Glucose Series =>
 Glucose level > 30mg/dL but < 40 mg/dL
immediate feeding and a repeat glucose 30 to
60 minutes after feeding
 If repeat glucose is > 40mg/dL monitor pre-
prandial glucoses and oral feedings every 3
hours for 24 hours
07/03/13 150S O MAIYEGUN MD
 Glucose is < 40mg/dL after initial feeding, and
result after one hour postprandial retesting is still
< 40mg/dL transfer to EPCH
 Glucose level > 40mg/dL will be treated orally by
breastfeeding every 1 to 3 hours expressed
formula and/or house formula every 2-3 hours
07/03/13 151S O MAIYEGUN MD
 Breastfeeding shall occur every 1 to 3 hours and
on demand
 If at 24 hours preprandial glucoses are < 50
mg/dL, preprandial glucose should be monitored
another 12 hours
 If preprandial glucoses are < 50 mg/dL at 36
hours, the Newborn will be transferred to EPCH
for further evaluation
07/03/13 152S O MAIYEGUN MD
 Problem—
◦ Infant with enlarged scrotum
 Plan—
◦ PE to palpate testes
◦ Transilluminate, if unable to palpate testes
◦ If scrotum is hard , indurated & discolored
Doppler U/S of testes
◦ Doppler U/S Testicular torsion surgery
consult immediately
07/03/13 153S O MAIYEGUN MD
07/03/13 154S O MAIYEGUN MD
07/03/13 155S O MAIYEGUN MD
 Problem—
◦ Evidence of hydronephrosis on prenatal ultrasound
◦ Enlarged palpable kidneys on PE
◦ Hydronephrosis on US done for other anomalies
07/03/13 156S O MAIYEGUN MD
07/03/13 157S O MAIYEGUN MD
158
 Plan—
◦ Check voiding—if no void in 24 hrs 
transfer to IMCN
◦ Minimal hydronephrosis grade 1 US and
reassurance if still minimal or negative
◦ If no urine >24hrs UA , BMP and follow
protocol for anuria >24hrs
07/03/13 158S O MAIYEGUN MD
◦ Moderate hydronephrosis grade 2  US, if still
moderate VCUG, If no urine >24hrs UA ,
BMP
◦ If VCUG is abnormal discuss with attending for
Mx, prophylactic abx
◦ Urology referral as out-pt or in-pt as
appropriately
07/03/13 159S O MAIYEGUN MD
160
 Plan—
◦ Grade 3 and 4 IMCN ( US, UA , BMP
,VCUG) discuss with attending & mother
◦ Urology referral as in-pt or out-pt as
appropriate
◦ Outpatient: FU U/S in 6 weeks (mild and
moderate) and if still abnormal VCUG
Urology referral as outpt (MAG3)
07/03/13 160S O MAIYEGUN MD
 Problem –
◦ Rectal temp > 101.0
 Plan –
◦ Unwrap pt & repeat temp in 30 mins
◦ Review maternal hx ( GBS , PROM , fever , s/s
of chorio )
 If positive  CBC stat or CBC & CRP if > 24
hrs
◦ If temp not decreased in 2 hrs – inform
atttending for transfer to IMCN
07/03/13 161S O MAIYEGUN MD
 Plan –
◦ Transfer to IMCN if symptomatic @ any time ,
temp > 102 , abnormal CBC or CRP > 20 or
rising
◦ IT ratio >0.2
◦ No d/c before 48 hrs of age
07/03/13 162S O MAIYEGUN MD
 Problem—
◦ Infant with increased muscle tone
 Plan—
◦ Perinatal hx for asphyxia , traumatic delivery ,
dysmorphic features
◦ Suspect drug withdrawal-
 Maternal hx
 Urine/Mec tox screen in baby
 Watch for other signs of withdrawal
07/03/13 163S O MAIYEGUN MD
 Plan—
◦ CT scan of head ( structural abnormalities,
hemorrhage )
◦ If dysmorphic features karyotyping
◦ No D/C prior to 48 hrs of age
07/03/13 164S O MAIYEGUN MD
 Problem—
◦ Infant with rectal temp < 97.6
 Plan –
◦ Evaluate environmental conditions
◦ Check gest age , weight , feedings
◦ Check maternal hx for possibility of ascending
infections
◦ Place under radiant warmer & check rectal
temp in 30 mins
07/03/13 165S O MAIYEGUN MD
 Plan—
◦ If persistent low temps > 2hrs – CBC , CRP
◦ If results abnormal  transfer to IMCN
◦ If 2 temp drops  CBC stat or CBC& CRP if >
24hrs If results abnormal ,transfer to IMCN
◦ If 3 temp drops  transfer to IMCN
07/03/13 166S O MAIYEGUN MD
 Problem—
◦ Floppy infant
 Plan—
◦ Complete CNS exam
◦ Maternal narcotic admn in last 4hrs PTD
 I/M Narcan ( 0.1 mg/kg )
◦ Maternal h/o of MgSO4 tx for PIH
 If present – magnesium level
07/03/13 167S O MAIYEGUN MD
 Plan—
◦ Birth h/o asphyxia ; apgar scores
◦ Check feeding
◦ Lab w/u—
 Mg , glucose , HCT , CBC ,CRP
 Head US (consult attending )
◦ Discuss with mother
◦ No d/c home prior to 48 hrs of age
07/03/13 168S O MAIYEGUN MD
I
07/03/13S O MAIYEGUN MD 169
 Problem—
◦ Maternal h/o diabetes
 Plan—
◦ PE for associated anomalies
◦ If no stool – discuss with attending
◦ Place on glucose monitoring series
 If 2 drops in glucose ( <40 mg %) while on
the series , transfer to IMCN
 If glucose is < 30 mg% at any time transfer
07/03/13 170S O MAIYEGUN MD
07/03/13 171S O MAIYEGUN MD
 Plan—
◦ Check HCT
 If > 65 ( central ) and symptomatic transfer
to SCN
◦ If jittery , check Se calcium & glucose at once
◦ Discuss with mother
◦ No d/c prior to 48 hrs of age
07/03/13 172S O MAIYEGUN MD
 Problem—
◦ Maternal h/o substance abuse during
pregnancy
◦ Maternal h/o substance abuse
◦ Maternal s/s suggestive of drug or alcohol use
◦ Positive toxicology in mother
◦ Unexplained irritability /jitteriness in baby
07/03/13 173S O MAIYEGUN MD
07/03/13 174S O MAIYEGUN MD
 Plan—
◦ Observe infant for s/s of withdrawal
◦ Check mother’s urine tox
◦ Send meconium and urine tox screen in baby
◦ If h/o cocaine use during pregnancy and urine
tox is positive in baby transfer to IMCN
07/03/13 175S O MAIYEGUN MD
◦ If h/o marijuana use & urine tox is negative in
baby, observe in MB for 48hrs
◦ If h/o amphetamine use during pregnancy or
urine tox is positive in baby IMCN
◦ If negative amphetamine in baby’s urine tox
screen observe in MB for 48hrs
07/03/13 176S O MAIYEGUN MD
 Plan –
◦ If baby’s & mother’s tox screen is negative –
observe in MB
◦ Check maternal HBsAg & HIV status
◦ ***Social service consult
◦ If any signs of withdrawal ,discuss with
attending or transfer to IMCN
◦ No d/c prior to 48 hrs of age
07/03/13 177S O MAIYEGUN MD
J
07/03/13S O MAIYEGUN MD 178
◦ All O+ and RH- mothers baby's blood group
and Coombs
◦ J-meter q shift (routine) on all babies
07/03/13 179S O MAIYEGUN MD
 Appears within 24 hours
 Level rises > 0.5mg/dl/hour
 Evidence of hemolysis(↑ bili,↑retics, ↓hct)
 Physical exam is abnormal
 Direct bilirubin > 20% of total bilirubin (Tbili)
07/03/13S O MAIYEGUN MD 180
◦ Causes:
◦ Excessive bruising
◦ Cephalhematoma
◦ Subdural hematoma
◦ IDM, breastfeeding
◦ Galatosemia
◦ G6PD deficiency
◦ Polycythemia
◦ Hemoglobinopathy, etc
07/03/13 181S O MAIYEGUN MD
 Plan—
 J-meter q shift
 Rh & ABO incompatibility J meter q 6 hrs or
12 hrs and T.bili and retics count earlier (6hr) or
at 24hrs (depending on severity)
 If retics is high and bili increasing Hct earlier
(6hr) or at 24hrs ( depending on severity)
07/03/13 182S O MAIYEGUN MD
***If any child is jaundiced in the 1st
24 hrs of life
and J-meter is above the curve
 Do initial total bilirubin ,if above the curve as
per the risks in the child  plan for
phototherapy (PT)
 If below the curve as per the risks then FU J-
meter q shift and fractionated bili q 12 hrs as
necessary
07/03/13 183S O MAIYEGUN MD
 If concerning do F.Bili q 4-6 hrs and decide
 If the rate of rise is greater than 0.5mg/dl/hr
or above the appropriate curve plan for PT
 If set-up for sepsis discuss transfer to
IMCN
07/03/13 184S O MAIYEGUN MD
 Obtain informed consent from mother prior to PT
 Start PT as per jaundice chart
 Use total bilirubin (do not subtract direct
bilirubin)
 Keep baby naked (genitalia and eyes covered)
 Monitor temperature and thermal environment
 Monitor input/output and increase fluid intake by
10ml/kg/PT
07/03/13MAIYEGUN MD 185
 Provide irradiance of at least 4µW/cm2/nm
 Provide irradiance 30 4µW/cm2/nm or > if
intensive PT is needed
 Use double or triple light with biliblanket if level
is high or rapidly rising
 Brief interruption for feeding will not interfere
with PT
07/03/13MAIYEGUN MD 186
 Lab w/u in infant’s under phototx—
◦ CBC at 24hr of life ; retics count (ABO or Rh)
◦ Follow F. bili q 6-12 hrs
◦ If bili rising then order hct and retics
◦ BMP ± Urine SG (dehydration)
◦ Urine reducing substance ( if Coombs neg) r/o
galactosemia
07/03/13 187S O MAIYEGUN MD
◦ Peripheral smear ( if Coombs neg and severe),
spherocytosis (Fx Hx) ,fragmented RBCs in
hemolysis
◦ If African/Asian/ Middle Eastern and severe
and Coombs neg  G6PD assay
◦ If there is setup for sepsis or abnormal labs
discuss for transfer to IMCN
07/03/13 188S O MAIYEGUN MD
◦ Discontinue phototx
 when bili decreases 2 consecutive times
 check bili at 12 hrs after stopping phototx
(d/c home if rebound does not exceed 3.0
mg/dl)
 Direct bilirubin > 20% of total bilirubin (Tbili)
07/03/13S O MAIYEGUN MD 189
◦ If direct bili rising, please inform attending
 Direct hyperbili >20% of the total bilirubin is
abnormal at any age
◦ Urine reducing substance (galactosemia)
◦ UA for bilirubin
◦ No PT or discontinue
◦ Physical exam (hepato-splenomegaly)
◦ Discuss for transfer to IMCN for further work-
up
07/03/13 190S O MAIYEGUN MD
07/03/13 191S O MAIYEGUN MD
07/03/13 192S O MAIYEGUN MD
 Jitteriness is not associated with ocular
deviation
 Generalized and symmetrical
 It is stimulus sensitive (easily stopped with
passive movement of the limb by holding onto
the baby’sarm)
 Also becoming most prominent after startle
 The movement resembles a tremor, and no
autonomic changes are associated with it
07/03/13 193S O MAIYEGUN MD
 Plan—
◦ Maternal h/o drug use, diabetes,infections
◦ Check initial CBC stat or CBC & CRP at
24hrs, if set-up for sepsis
◦ Urine and mec toxicology screen
◦ Ionized Ca , glucose level
◦ If severe, check Mg ,Phosphate, Parathyroid
hormone (PTH)
07/03/13 194S O MAIYEGUN MD
 Plan—
◦ Discuss with attending if CBC ,CRP abnormal
◦ Hypocalcemia: If Se Ca is < 2.0mmol/L
(8.0mg/dl) and ionized calcium < 1.0mmol/L
(4.0mg/dl) in symptomatic NB discuss
◦ Se calcium < 7.0 mg /dl and ionized calcium <
0.9mmol/L (3.6mg/dl) asymptomatic discuss
07/03/13 195S O MAIYEGUN MD
◦ If Se Magnesium < 1.0 mg/dl with
hypocalcaemia –discuss for transfer
◦ If Se Glucose < 40 mg/dl --- follow glucose
protocol
◦ FU results for discussion
07/03/13 196S O MAIYEGUN MD
L
07/03/13S O MAIYEGUN MD 197
 Problem—
◦ BW > 3800gms
◦ Wt > 90 %ile for gestational age
 Plan—
◦ Place on glucose series & follow protocol
◦ Check HCT
◦ Maternal h/o diabetes
◦ PE for brachial plexus injuries & clavicular
fractures
07/03/13 198S O MAIYEGUN MD
M
07/03/13S O MAIYEGUN MD 199
 Problem—
◦ Head circumference > 38.0 cm
◦ HC disproportionately greater than 50th
% tile to
BW & length
 Plan—
◦ Check HC yourself
◦ Family hx of large heads
◦ Maternal h/o TORCH infections
◦ Check head for split sutures
07/03/13 200S O MAIYEGUN MD
07/03/13 201S O MAIYEGUN MD
 Plan—
◦ Head US if abnormally split sutures
◦ Transilluminate skull
◦ If transillumination positive or hydrocephalus
present, inform attending for discussion
◦ CT head as needed
07/03/13 202S O MAIYEGUN MD
 Mom given MgSO4:
 If term baby, stable in nursery or MB and
asymptomatic: NO serum magnesium
necessary, but monitor closely
 If symptomatic (preterm, poor feeding, low apgar
scores, apnea, resp distress or frequent
desaturation, cyanosis, no meconium in
>48hours) then  serum magnesium ± transfer
to IMCN/ICN as appropriate
07/03/13 203S O MAIYEGUN MD
 No meconium in >48hours
 99% of term and 76% of preterm pass stool in
the 1st
24hrs
 99% of preterm pass stool in the 48hrs
 Plans :
 Medications in mother: MgSO4, opiates
 Imperforate anus, intestinal obstruction,
hirschsprung disease, malrotation, meconium
plug/ileus, duodenal atresia, small left colon
syndrome (IDM)
07/03/13 204S O MAIYEGUN MD
 PE: Document patency of the anus (rectal
thermometer or feeding tube
 Abdominal exam ( distension, rigidity, BS, mass)
 CBC stat or CBC& CRP if set up for sepsis
 KUB stat
 If Hx of drug use urine and mec tox screen
 S. magnesium level if maternal MgSO4
 FT4 and TSH
07/03/13 205S O MAIYEGUN MD
 If all labs normal, If no meconium > 48 hours
consider barium enema to evaluate for
Hirschsprung disease
 Surgical consultation for rectal biopsy
 ***Discuss the use of suppository after 48hours
with attending
 No discharge until passage of stool
07/03/13S O MAIYEGUN MD 206
 Problem—
◦ Infant with small head ( HC <10%ile) or greater
than 50th
percentile difference between head &
weight /length
 Plan—
◦ Maternal hx for TORCH infections , drug or
alcohol use ,Rxn drugs ( phenytoin)
◦ Fam hx of small heads & MR
07/03/13 207S O MAIYEGUN MD
 Plan—
◦ Head US /CT scan
◦ If needed Total IgM for TORCHES & Urine
culture for CMV
◦ Discuss with faculty
07/03/13 208S O MAIYEGUN MD
 Perinatal Hx
 Exam for resp distress
 Pulse ox stat and continuous as needed
 CXR to r/o abnormalities
 CBC stat or CBC& CRP(>24hrs) if set up for
sepsis
 If significant abnormal results consider
transfer to EPCH
 If grunting (discuss and consider transfer)
07/03/13S O MAIYEGUN MD 209
07/03/13 210S O MAIYEGUN MD
Apparently healthy infant noted to have heart
murmur on PE
 Grade 1-2 murmur @ birth
 Acyanotic with no significant problems ,re-
examine @ 2nd
day of life
 Grade 3-4 on day 1 or significant murmur found
on 2nd
day of life
07/03/13 211S O MAIYEGUN MD
 Plan—
◦ Full cardiac exam
 4 limb BP’s
 Pulse ox- spot or continuous as
appropriate
 Hepatosplenomegaly
 Feeding
 CXR (cardiac shape)
 Echocardiogram (specific and diagnostic)
◦ EKG as needed
07/03/13 212S O MAIYEGUN MD
 Plan—
◦ Cyanosis or severe respiratory distress 
transfer to IMCN
◦ Grade 1-2 murmur on 1st
day of life with
symptoms
◦ Discuss with faculty for possible transfer to
IMCN/ICN
07/03/13 213S O MAIYEGUN MD
P
07/03/13 214S O MAIYEGUN MD
 Problem—
◦ Red/purple , non-blanching spots on skin/ face
 Plan—
◦ Maternal hx of TORCH infection or at risk for
ascending infection
◦ Maternal labs –thrombocytopenia
◦ CBC stat and CBC and CRP at 24hrs
◦ Perinatal h/o asphyxia , nuchal cord , trauma ,
forceps
◦ Observe for signs of sepsis & discuss with
attending
07/03/13 215S O MAIYEGUN MD
 All high risk babies are screen with capillary
hematocrit
 Central venous hematocrit >65%
 If capillary hematocrit is more than 65%
repeat from central venous from a cubital vein
◦ Central HCT ( no tourniquet , deep vein
, no femoral sticks )
◦ Check for jaundice ; check Se glucose
07/03/13 216S O MAIYEGUN MD
 Symptoms of hyperviscosity: Plethora
 temperature instability
 feeding problems
 plethora
 irritability
 lethargy
 hypoglycemia
 respiratory distress
 hypoperfusion
07/03/13 217S O MAIYEGUN MD
 Central Hct is 65-69% and the infant is
asymptomatic no intervention is warranted,
repeat central Hct at 24 hrs
 If ≥ 65 % and the infant is symptomatic IMCN
for partial exchange reduction
 If >70% IMCN for a partial reduction exchange
 Discuss with faculty
07/03/13 218S O MAIYEGUN MD
 Ulnar or postaxial polydactyly commonly
isolated in African black children, autosomal
dominant transmission
 More frequent in blacks than in whites and is
more frequent in male children
07/03/13 220S O MAIYEGUN MD
 Ulnar or postaxial polydactyly commonly
isolated in African black children, autosomal
dominant transmission
 More frequent in blacks than in whites and is
more frequent in male children
07/03/13 221S O MAIYEGUN MD
 In contrast, postaxial polydactyly seen in white
children is usually syndromic and associated
with an autosomal recessive transmission
 Radial or preaxial polydactyly is frequently
associated with several syndromes
 Any other forms of polydactyly/syndacytly/cleft
hand or feet need orthopedic consult
07/03/13 222S O MAIYEGUN MD
 Problem—
◦ Skin tag or extra digit on healthy infant
◦ Look for other dysmorphic features
◦ Document pre or post-axial polydactyl
 Plan—
◦ Inform mother
◦ If skin tag has a thin pedicle tie off with vicryl
suture after obtaining informed consent from
mother
07/03/13 223S O MAIYEGUN MD
◦ Extra digit—
 X-rays to document if bone present
◦ If no bone  can tie off with vicryl suture after
obtaining informed consent from mother
 If bone present refer to pediatrics
orthopedics as outpatient
 Any lower limb polydactyl or preaxial need
referral to orthopedics
07/03/13 224S O MAIYEGUN MD
R
07/03/13S O MAIYEGUN MD 225
 Persistent respiratory distress beyond 4 hrs
transitional period
 Retractions (I/C and S/C), moaning, grunting
 Respiratory rate: persistently >60/min
 Frequent desaturations
 Cyanotic episodes
 Plans: CXR stat (to r/o pneumonia,
pneumothorax, cardiac shape )
 CBC and if >24hrs CBC & CRP
 Discuss with faculty for transfer to IMCN
07/03/13 226S O MAIYEGUN MD
07/03/13 227S O MAIYEGUN MD
 Problem –
◦ Mother with positive serology for syphilis
◦ RPR and TPPA
 Plan—
◦ RPR on baby
◦ Detailed maternal hx ( confirmatory labs &
treatment hx)
◦ If mothers TPPA negative no issues
07/03/13 228S O MAIYEGUN MD
 Plan—
◦ If mothers TPPA is positive 
◦ detailed h/o treatment
 documented evidence of drug used
(Penicillin)
 timing of tx
 decreased titers 4x after tx
 evidence of tx of spouse )
07/03/13 229S O MAIYEGUN MD
◦ Transfer to IMCN for full work-up
◦ If baby’s titer is at least 4 X maternal titer
◦ No h/o tx
 Last dose of PCN within the last month prior
to delivery
 Drug other than PCN used
 No evidence of decreased titers
 Possibility of re-infection( no tx of spouse)
07/03/13 230S O MAIYEGUN MD
 Plan
 If mothers TPPA + & documentation of
satisfactory treatment available (follow the CDC
guideline attached)
 refer to ID as out-pt after discussion with
faculty
◦ Transfer to IMCN if infants RPR > 1:4 after
discussion with faculty
07/03/13 231S O MAIYEGUN MD
S
07/03/13 232S O MAIYEGUN MD
 Problem—
◦ Maternal h/o SLE
 Plan—
◦ EKG ( bradycardia , complete ht block)
◦ CBC (thrombocytopenia/leukopenia/anemia)
◦ Examine skin for rash ,if present – no sun
exposure, self limiting
◦ FU with PCP
07/03/13 233S O MAIYEGUN MD
 Problem—
◦ Weight < 10%ile for age
 Plan—
◦ Determine gestational age
◦ Determine IUGR status
◦ Maternal h/o placental insufficiency , TORCH
infections , nutrition hx ,h/o chronic diseases &
drug use )
07/03/13 234S O MAIYEGUN MD
 Plan
 Place on glucose series
◦ Check HCT
◦ Follow feedings
◦ Follow temperatures
◦ If hx suggestive of TORCH infection –CBC ,
Total IgM & discuss with attending
07/03/13 235S O MAIYEGUN MD
 Problem—
◦ Stuffy nose , trouble breathing
 Plan—
◦ Check patency of nares ( pass 8Fr feeding
tube B/L ) auscultate for air passing through
each nare after blocking the other one)
◦ Pulse ox as needed
◦ Normal saline nasal drops and bulb suction
◦ Bedside Humidifier (cool mist)
07/03/13 236S O MAIYEGUN MD
 Plan—
 Check maternal h/o syphilis ( snuffles)
◦ Follow feedings
◦ If severe discuss with attending
◦ Bedside Humidifier (cool mist) @ home
07/03/13 237S O MAIYEGUN MD
 Bleeding in the potential space between the
periosteum and the galea aponeurosis
 Risk factors as in cephalhematoma
 Fluctuant boggy mass and crosses the suture
lines
 Hemorrhagic shock and significant
hyperbilirubinemia
 Labs for coagulopathy
 Close observation, if severe  IMCN
07/03/13 238S O MAIYEGUN MD
T
07/03/13S O MAIYEGUN MD 239
 HR persistently more than 160-175bpm or >
2SD above the mean for age, asleep or awake
 Plan:
 Maternal Hx of thyroid disorder
 Fever  check temperature
 Birth Hx (forceps or vaccum)
 EKG stat
 CXR and CBC stat and >24hrs CBC and CRP
 Inform attending for transfer to IMCN
07/03/13 240S O MAIYEGUN MD
 Problem—
◦ Infant born with teeth ( loose or firm) ;either
visible or soft mucoid tissue cysts along
alveolar ridge with palpable loose tooth in it
 Plan—
◦ If loose  talk with mother regarding need for
removal refer to dentist
◦ If well embedded  can FU later with dentist
07/03/13 241S O MAIYEGUN MD
07/03/13 242S O MAIYEGUN MD
 Problem—
◦ Empty scrotum or hemiscrotum
 Plan—
◦ Unilateral cryptorchidism – no intervention 
Urology consult as out-pt
◦ Bilateral, with no palpable testes in canal
abdominal US (testes, ovaries, adrenals)
◦ If U/S shows abdominal testes  Urology
consult as out-pt
07/03/13 243S O MAIYEGUN MD
◦ Bilateral with palpable testes in inguinal
canal no intervention recheck gestational
age
◦ If no testes on US ambiguous genitalia
protocol
07/03/13 244S O MAIYEGUN MD
 Problem—
◦ Maternal h/o thrombocytopenia at time of
delivery or during pregnancy
◦ Platelet count< 150,000
 Plan: Repeat platelet count before decision is
made
 CBC with platelet on baby
◦ If < 50,000 – transfer to IMCN
◦ If > 50,000 – repeat in 24 hrs
◦ Check baby for petechiae ,bruising, oozing
from cord
07/03/13 245S O MAIYEGUN MD
07/03/13S O MAIYEGUN MD 246
 4% of newborns
 Can breastfeed without difficulty, but in some
cases, a tight frenulum makes latching on
difficult
 No evidence based reason to clip the frenulum
in the nursery
 In cases of difficulty feeding , frenotomy may be
indicated
07/03/13S O MAIYEGUN MD 247
 Problem—
◦ Single umbilical artery
 Plan—
◦ Renal US
◦ Check for urination
◦ Check for dysmorphic features
07/03/13 248S O MAIYEGUN MD
249SOMAIYEGUN MD07/03/13 249S O MAIYEGUN MD
U
07/03/13 250S O MAIYEGUN MD
 Urate crystals look different from blood in the
newborn’s diaper but can be confused
 They tend to sit on the surface of the diaper and
are iridescent and completely benign
 M=F
 More observed in boys
07/03/13S O MAIYEGUN MD 251
 No urine in > 24hrs
 100% of neonates pass urine in 24 hours Plan:
 Maternal History: olighydramnios (renal
anomalies)
 Prenatal history of fetal hydronephrosis, kidney
anomalies
 Check L& D papers
 MOST likely reason: undocumented void in
the delivery room
07/03/13 252S O MAIYEGUN MD
 Make sure there is adequate intake, lactation
consult if necessary
 Supplement with formula if needed
07/03/13 253S O MAIYEGUN MD
 If no urine more than 24hrs 
 Placed a cotton ball between the labia or a urine
bag ( check urine)
 Bladder palpable (manual compression may
initiate voiding) if a boy think of PUV
 Bladder catheterization If no urine US
bladder, kidneys IMCN for further workup
 Check BP, BMP
 No discharge until the passage of stool and
urine can be documented
07/03/13S O MAIYEGUN MD 254
 There is no immediate danger to the baby, so
parents can sign that they do not consent
 There is no need for social service consult
07/03/13S O MAIYEGUN MD 255
 Projectile and forceful, vomiting with feedings
>2, ± abdominal distension/tenderness
 Greenish emesis or Bloody emesis
 Confirm passage of meconium
 Look for dysmorphic features (Down Syndrome)
07/03/13 256S O MAIYEGUN MD
 Plan: Hx of sepsis set-up
 KUB stat (NEC, pneumoperitoneum, double
bubble, etc )
 CBC stat or CBC & CRP >24hrs
 Inform faculty
07/03/13 257S O MAIYEGUN MD
Neonatal
Pictures
07/03/13S O MAIYEGUN MD 258
 Most common
 Dermal melanocytosis
 96% of African-American
 46% of Hispanic
 10% of white children
 Common locations are the buttocks, midsacral but
shoulders and extremities may be involved
07/03/13 259S O MAIYEGUN MD
07/03/13 260S O MAIYEGUN MD
Reassurance
Reassurance
07/03/13 262S O MAIYEGUN MD
Reassurane
 Sebaceous retention cyst
 These small, whitish-yellow
papules are found close to
the skin surface, being
particularly common around
the eyes and midface
 Reassurance
07/03/13 263S O MAIYEGUN MD
 Note the yellowish
papules on the nose of
this infant
 Sebaceous gland
hyperplasia
 Reassurance
07/03/13 264S O MAIYEGUN MD
 Caused by sweat retention
 Characterized by a vesicular eruption with
subsequent maceration and obstruction of the
eccrine ducts
 Keratinous plugging of eccrine ducts and the
escape of eccrine sweat into the skin below the
level of obstruction
 Miliaria crystallina (sudamina): clear superficial
pinpoint vesicles without an inflammatory areola
 Miliaria rubra (prickly heat): deeper level of sweat
gland obstruction, and characterized by small
discrete erythematous papules, vesicles, or
papulovesicles
 Sweat rash and heat
rash :ducts connecting
sweat glands with the
surface of the skin get
blocked & perspiration
gets trapped under the
skin
 Reassurance
07/03/13S O MAIYEGUN MD 267
Reassurance
 Numerous tiny
erythematous papular
lesions on face, neck,
and upper trunk
 Reassurance
 Numerous tiny
papulo-pustular
lesions
 Cytologic exam
:inflammatory cells
 Gram staining may
reveal gram+cocci
(staphylococci)
 Sepsis workup and
antibiotics as needed
07/03/13 271S O MAIYEGUN MD
Reassurance
07/03/13 272S O MAIYEGUN MD
 Pearls (sebaceous retention cyst) may be found in a
variety of locations in the newborn
 The tip of the foreskin is another relatively common
location
 The pearl is a small, firm, white nodule that contains
keratin
 It will spontaneously exfoliate and resolve with time
 It is a normal finding and is not a contraindication to
circumcision, if desired
07/03/13 273S O MAIYEGUN MD
 Numerous yellow papules
and pustules are surrounded
by large intensely
erythematous rings
 50% of full terms
 Rare in preterms
 Eosinophils + (Wright stain)
 Reassurance
07/03/13 274S O MAIYEGUN MD
 Note the reticulated bluish-
purple mottling of this infant's
thigh
 -Vasomotor instability
 -Normal
 -Poor perfusion, hypovolumia
 -septic shock
 -Cornelia de Lange
syndrome
 -Down syndrome
07/03/13 275S O MAIYEGUN MD
 Nevus flammeus
neonatorum: a typical light
red splotchy area is seen at
the nape of the neck and
forehead
 Dilated superficial capillaries
 Reassurance
07/03/13 276S O MAIYEGUN MD
 Characteristic purplish-red
lesion covering nearly half of
face
 Capillary malformation
 If neurologic signs MRI
brain and Ophthalmology
consult
 Reassurance
07/03/13 277S O MAIYEGUN MD
 Multiple soft, red, raised
lesions dot the back and
arms
 Reassurance
07/03/13 278S O MAIYEGUN MD
 The vessels that make
up this large, partially
compressible lesion are
deep beneath the skin
surface but still impart
a bluish hue to the
overlying skin. Note the
indistinctness of the
margins.
 MRI chest
 The hemangioma on
this child's nasal
bridge has both
superficial and deep
components.
 MRI brain
 A, Two small nevi with
differing degrees of
hyperpigmentation
 B, The giant nevus
covering the lower back
and buttocks, is uniformly
pigmented and has
smaller satellite nevi.
 MRI spine
 Red papules and pustules
are present over the nose
and cheeks
07/03/13 282S O MAIYEGUN MD
 Present at birth
 Pustules without surrounding
erythema
 Ruptured pustules with
hyperpigmented macules
with a rim of surrounding
scale
 Occur in 5% African-
American, rare in other racial
groups
 Pustules contain PMN’s
07/03/13 283S O MAIYEGUN MD
07/03/13 284S O MAIYEGUN MD
07/03/13 285S O MAIYEGUN MD
07/03/13 286S O MAIYEGUN MD
 While the blister created by the infant sucking on his
extremity in the womb may still be intact at the time of
delivery
 Often it appears as a flat, scabbed, healing area (as
shown)
 Sucking blisters are solitary lesions that occur only in
areas accessible to the infant's mouth
 They are benign and resolve spontaneously
 The appearance and location of the lesion is usually
sufficient for diagnosis, but if the infant is observed
sucking on the affected area, the diagnosis is certain
07/03/13 287S O MAIYEGUN MD
Breakage of small vessels
during the pressure of
delivery
Reassurance
Education on
nasolacrimal
duct massage
Refer to
ophthalmology
on discharge
for
recanalization
MUCOCELE
MUCOCELE
Reassurance and FU
Reassurance and FU
Reassurance and FU
Reassurance and FU
with plastic surgery/
dermatologist if severe
Reassurance and FU
with plastic surgery/
dermatologist if severe
Reassurance and FU
with plastic surgery/
dermatologist if severe
 Normal
 Scalp electrode placement
 Vascular compromise
 Methimazole
 Trisomy 13
07/03/13S O MAIYEGUN MD 297
Reassurance and FU
Reassurance
and FU
NEONATAL SLE
Screen for SLE abx,
Congenital heart block or
thrombocytopenia
NEONATAL LUPUS
Screen for SLE
NEONATAL
SLE
Screen for SLE abx,
Congenital heart block
or thrombocytopenia
Rubella, dermal
extramedullary
hematopoiesis, infiltrative
neoplastic lesions of the
skin, and cutaneous
vascular anomalies
NICU transfer for workup
07/03/13S O MAIYEGUN MD 305
07/03/13S O MAIYEGUN MD 306
 http://newborns.stanford.edu/PhotoGallery
 Atlas of Pediatric Physical Diagnosis : Basil J.
Zitelli MD, Holly W. Davis MD
 Nelson Textbook of Pediatrics
 The Atlas of Emergency Medicine .Chapter 15.
Child Abuse
 Lynne Uhring, MD, FAAP  Frequently Asked
Questions About Newborn Babies
07/03/13 307S O MAIYEGUN MD
 Carrie L. Byington and Carol J. Baker: CDC
updates guidelines on prevention of perinatal
GBS ,AAP News, Dec 2012
 Revised previous edition by Dr. N Singh
 Guidelines for Perinatal Care, 7th Edition Jointly
developed by the AAP Committee on Fetus and
Newborn and ACOG Committee on Obstetric
Practice
07/03/13S O MAIYEGUN MD 308
 Red Book: 2012 Report of the Committee on
Infectious Diseases, 29th Edition
 Lynne Uhring, MD, FAAP  Frequently Asked
Questions About Newborn Babies
 Neonatology Management, procedure, on-call
problems, diseases and drugs: 6th
Edition,
Gomella TL
07/03/13S O MAIYEGUN MD 309

More Related Content

What's hot

SMALL FOR GESTATIONAL AGE,LARGE FOR GESTATIONAL AGE -SSJ, CALICUT MEDICAL COL...
SMALL FOR GESTATIONAL AGE,LARGE FOR GESTATIONAL AGE -SSJ, CALICUT MEDICAL COL...SMALL FOR GESTATIONAL AGE,LARGE FOR GESTATIONAL AGE -SSJ, CALICUT MEDICAL COL...
SMALL FOR GESTATIONAL AGE,LARGE FOR GESTATIONAL AGE -SSJ, CALICUT MEDICAL COL...
govt. medical college, kozhikode
 
Care of child with incubator
Care of child with incubatorCare of child with incubator
Care of child with incubator
Sabita Paudel
 
Neonatal Hypoglycemia
Neonatal HypoglycemiaNeonatal Hypoglycemia
Neonatal Hypoglycemia
David Mendez
 

What's hot (20)

IMCI
IMCIIMCI
IMCI
 
Cardiotocography (CTG)
Cardiotocography (CTG)Cardiotocography (CTG)
Cardiotocography (CTG)
 
Assessment of Gestational age
Assessment of Gestational age Assessment of Gestational age
Assessment of Gestational age
 
SMALL FOR GESTATIONAL AGE,LARGE FOR GESTATIONAL AGE -SSJ, CALICUT MEDICAL COL...
SMALL FOR GESTATIONAL AGE,LARGE FOR GESTATIONAL AGE -SSJ, CALICUT MEDICAL COL...SMALL FOR GESTATIONAL AGE,LARGE FOR GESTATIONAL AGE -SSJ, CALICUT MEDICAL COL...
SMALL FOR GESTATIONAL AGE,LARGE FOR GESTATIONAL AGE -SSJ, CALICUT MEDICAL COL...
 
Nursing care of a baby undergoing phototherapy
Nursing care of a baby undergoing phototherapyNursing care of a baby undergoing phototherapy
Nursing care of a baby undergoing phototherapy
 
Newborn feeding
Newborn feedingNewborn feeding
Newborn feeding
 
Fetal movements
Fetal movementsFetal movements
Fetal movements
 
Premature baby
Premature babyPremature baby
Premature baby
 
Neonatal jaundice
Neonatal jaundice Neonatal jaundice
Neonatal jaundice
 
IMNCI: Diarrhoea
IMNCI: DiarrhoeaIMNCI: Diarrhoea
IMNCI: Diarrhoea
 
Neonatal hypoglycemia
Neonatal hypoglycemiaNeonatal hypoglycemia
Neonatal hypoglycemia
 
Intrauterine Growth Restriction (IUGR) / Small For gestational Age
Intrauterine Growth Restriction (IUGR) / Small For gestational Age Intrauterine Growth Restriction (IUGR) / Small For gestational Age
Intrauterine Growth Restriction (IUGR) / Small For gestational Age
 
Management of neonatal hypoglycemia ppt
Management of neonatal hypoglycemia pptManagement of neonatal hypoglycemia ppt
Management of neonatal hypoglycemia ppt
 
Meningitis In Children
Meningitis  In ChildrenMeningitis  In Children
Meningitis In Children
 
Neonatal warning signs
Neonatal warning signsNeonatal warning signs
Neonatal warning signs
 
Newborn assessment
Newborn assessment   Newborn assessment
Newborn assessment
 
BFHI- update
BFHI- updateBFHI- update
BFHI- update
 
Care of child with incubator
Care of child with incubatorCare of child with incubator
Care of child with incubator
 
How to read a CTG دكتور صلاح رزق.pptx
How to read a CTG دكتور صلاح رزق.pptxHow to read a CTG دكتور صلاح رزق.pptx
How to read a CTG دكتور صلاح رزق.pptx
 
Neonatal Hypoglycemia
Neonatal HypoglycemiaNeonatal Hypoglycemia
Neonatal Hypoglycemia
 

Viewers also liked

under five clinic.
under five clinic.under five clinic.
under five clinic.
sangita dey
 
Under fiv clinic
Under fiv clinicUnder fiv clinic
Under fiv clinic
Kiran
 
Saving Babies: Inheritance =Jing
Saving Babies: Inheritance =JingSaving Babies: Inheritance =Jing
Saving Babies: Inheritance =Jing
Heather Bruce
 
Under fives clinic
Under fives clinicUnder fives clinic
Under fives clinic
qazi1210
 
Anemia in Children, by Audace NIYIGENA
Anemia in Children, by Audace NIYIGENAAnemia in Children, by Audace NIYIGENA
Anemia in Children, by Audace NIYIGENA
Audace L'audacieux
 
Regular health check up camp
Regular health check up campRegular health check up camp
Regular health check up camp
Atique Mehdi
 

Viewers also liked (17)

Wbc
WbcWbc
Wbc
 
under five clinic.
under five clinic.under five clinic.
under five clinic.
 
Under fiv clinic
Under fiv clinicUnder fiv clinic
Under fiv clinic
 
Saving Babies: Inheritance =Jing
Saving Babies: Inheritance =JingSaving Babies: Inheritance =Jing
Saving Babies: Inheritance =Jing
 
Format 2016: tachypnoea in a well baby: what to do next?
Format 2016: tachypnoea in a well baby: what to do next?Format 2016: tachypnoea in a well baby: what to do next?
Format 2016: tachypnoea in a well baby: what to do next?
 
Health Camp
Health CampHealth Camp
Health Camp
 
Health Camp
Health CampHealth Camp
Health Camp
 
A report -Health check up Camp
A report -Health check up Camp A report -Health check up Camp
A report -Health check up Camp
 
oxygen therapy
oxygen therapy  oxygen therapy
oxygen therapy
 
Non-Invasive Ventilation for Preterm Infants
Non-Invasive Ventilation for Preterm InfantsNon-Invasive Ventilation for Preterm Infants
Non-Invasive Ventilation for Preterm Infants
 
care of children with Epispadias,hypospadias,ectopia vescica
care of children with Epispadias,hypospadias,ectopia vescica care of children with Epispadias,hypospadias,ectopia vescica
care of children with Epispadias,hypospadias,ectopia vescica
 
Under fives clinic
Under fives clinicUnder fives clinic
Under fives clinic
 
NATIONAL AND INTERNATIONAL ORGANIZATION RELATED TO CHILD HEALTH
NATIONAL AND INTERNATIONAL ORGANIZATION RELATED TO CHILD HEALTHNATIONAL AND INTERNATIONAL ORGANIZATION RELATED TO CHILD HEALTH
NATIONAL AND INTERNATIONAL ORGANIZATION RELATED TO CHILD HEALTH
 
Anemia in Children, by Audace NIYIGENA
Anemia in Children, by Audace NIYIGENAAnemia in Children, by Audace NIYIGENA
Anemia in Children, by Audace NIYIGENA
 
Regular health check up camp
Regular health check up campRegular health check up camp
Regular health check up camp
 
Out patient services
Out patient servicesOut patient services
Out patient services
 
Newborn examination
Newborn examinationNewborn examination
Newborn examination
 

Similar to Well Baby Nursery Guidelines

Management-of-Intrauterine-Fetal-Demise-June-2018.pptx
Management-of-Intrauterine-Fetal-Demise-June-2018.pptxManagement-of-Intrauterine-Fetal-Demise-June-2018.pptx
Management-of-Intrauterine-Fetal-Demise-June-2018.pptx
SamiIbrahim28
 
Mternal death review lecture by dr. evelina r. castro 102413
Mternal death review lecture by dr. evelina r. castro   102413Mternal death review lecture by dr. evelina r. castro   102413
Mternal death review lecture by dr. evelina r. castro 102413
Jesart De Vera
 
Gestational diabetes case study 2nd one
Gestational diabetes case study 2nd oneGestational diabetes case study 2nd one
Gestational diabetes case study 2nd one
Lisette Allender
 

Similar to Well Baby Nursery Guidelines (20)

Antenatal care and high risk assessment1
Antenatal care and high risk assessment1Antenatal care and high risk assessment1
Antenatal care and high risk assessment1
 
Well Newborn Nursery Guidelines 2021
Well Newborn Nursery Guidelines 2021 Well Newborn Nursery Guidelines 2021
Well Newborn Nursery Guidelines 2021
 
Antenatal assessment
Antenatal assessmentAntenatal assessment
Antenatal assessment
 
Pre Pregnancy-101
Pre Pregnancy-101Pre Pregnancy-101
Pre Pregnancy-101
 
PRENATAL CARE main.pptx
PRENATAL CARE main.pptxPRENATAL CARE main.pptx
PRENATAL CARE main.pptx
 
Management-of-Intrauterine-Fetal-Demise-June-2018.pptx
Management-of-Intrauterine-Fetal-Demise-June-2018.pptxManagement-of-Intrauterine-Fetal-Demise-June-2018.pptx
Management-of-Intrauterine-Fetal-Demise-June-2018.pptx
 
Antenatal & Postnatal Care
Antenatal & Postnatal CareAntenatal & Postnatal Care
Antenatal & Postnatal Care
 
Mternal death review lecture by dr. evelina r. castro 102413
Mternal death review lecture by dr. evelina r. castro   102413Mternal death review lecture by dr. evelina r. castro   102413
Mternal death review lecture by dr. evelina r. castro 102413
 
Gestational Diabetes Mellitus
Gestational Diabetes MellitusGestational Diabetes Mellitus
Gestational Diabetes Mellitus
 
Gestational diabetess
Gestational diabetessGestational diabetess
Gestational diabetess
 
Induction of Labour
Induction of LabourInduction of Labour
Induction of Labour
 
Atlas important aspects of antenatal care
Atlas important aspects of antenatal careAtlas important aspects of antenatal care
Atlas important aspects of antenatal care
 
Clinic psychosocial Case on Antenatal cum Post Natal Care
Clinic psychosocial Case on Antenatal cum Post Natal CareClinic psychosocial Case on Antenatal cum Post Natal Care
Clinic psychosocial Case on Antenatal cum Post Natal Care
 
Neurodevelopmental follow up
Neurodevelopmental follow upNeurodevelopmental follow up
Neurodevelopmental follow up
 
Prenatal care
Prenatal carePrenatal care
Prenatal care
 
Parto pretermino tardio y a termino temprano
Parto pretermino tardio y a termino tempranoParto pretermino tardio y a termino temprano
Parto pretermino tardio y a termino temprano
 
Interesting Update on Recurrent Miscarriage for Indian Gynaecologoists D...
Interesting Update on  Recurrent  Miscarriage  for Indian Gynaecologoists   D...Interesting Update on  Recurrent  Miscarriage  for Indian Gynaecologoists   D...
Interesting Update on Recurrent Miscarriage for Indian Gynaecologoists D...
 
Follow up of High Risk Neonates.. Dr.Padmesh
Follow up of High Risk Neonates.. Dr.Padmesh Follow up of High Risk Neonates.. Dr.Padmesh
Follow up of High Risk Neonates.. Dr.Padmesh
 
ANC- PRESENTATION OF ANC,PNC & DC.pptx
ANC- PRESENTATION OF ANC,PNC & DC.pptxANC- PRESENTATION OF ANC,PNC & DC.pptx
ANC- PRESENTATION OF ANC,PNC & DC.pptx
 
Gestational diabetes case study 2nd one
Gestational diabetes case study 2nd oneGestational diabetes case study 2nd one
Gestational diabetes case study 2nd one
 

Recently uploaded

Dehradun Call Girls Service {8854095900} ❤️VVIP ROCKY Call Girl in Dehradun U...
Dehradun Call Girls Service {8854095900} ❤️VVIP ROCKY Call Girl in Dehradun U...Dehradun Call Girls Service {8854095900} ❤️VVIP ROCKY Call Girl in Dehradun U...
Dehradun Call Girls Service {8854095900} ❤️VVIP ROCKY Call Girl in Dehradun U...
Sheetaleventcompany
 
Kolkata Call Girls Service ❤️🍑 9xx000xx09 👄🫦 Independent Escort Service Kolka...
Kolkata Call Girls Service ❤️🍑 9xx000xx09 👄🫦 Independent Escort Service Kolka...Kolkata Call Girls Service ❤️🍑 9xx000xx09 👄🫦 Independent Escort Service Kolka...
Kolkata Call Girls Service ❤️🍑 9xx000xx09 👄🫦 Independent Escort Service Kolka...
Sheetaleventcompany
 
❤️Amritsar Escorts Service☎️9815674956☎️ Call Girl service in Amritsar☎️ Amri...
❤️Amritsar Escorts Service☎️9815674956☎️ Call Girl service in Amritsar☎️ Amri...❤️Amritsar Escorts Service☎️9815674956☎️ Call Girl service in Amritsar☎️ Amri...
❤️Amritsar Escorts Service☎️9815674956☎️ Call Girl service in Amritsar☎️ Amri...
Sheetaleventcompany
 
Premium Call Girls Dehradun {8854095900} ❤️VVIP ANJU Call Girls in Dehradun U...
Premium Call Girls Dehradun {8854095900} ❤️VVIP ANJU Call Girls in Dehradun U...Premium Call Girls Dehradun {8854095900} ❤️VVIP ANJU Call Girls in Dehradun U...
Premium Call Girls Dehradun {8854095900} ❤️VVIP ANJU Call Girls in Dehradun U...
Sheetaleventcompany
 
Cara Menggugurkan Kandungan Dengan Cepat Selesai Dalam 24 Jam Secara Alami Bu...
Cara Menggugurkan Kandungan Dengan Cepat Selesai Dalam 24 Jam Secara Alami Bu...Cara Menggugurkan Kandungan Dengan Cepat Selesai Dalam 24 Jam Secara Alami Bu...
Cara Menggugurkan Kandungan Dengan Cepat Selesai Dalam 24 Jam Secara Alami Bu...
Cara Menggugurkan Kandungan 087776558899
 
Call Girl in Chennai | Whatsapp No 📞 7427069034 📞 VIP Escorts Service Availab...
Call Girl in Chennai | Whatsapp No 📞 7427069034 📞 VIP Escorts Service Availab...Call Girl in Chennai | Whatsapp No 📞 7427069034 📞 VIP Escorts Service Availab...
Call Girl in Chennai | Whatsapp No 📞 7427069034 📞 VIP Escorts Service Availab...
amritaverma53
 

Recently uploaded (20)

Dehradun Call Girls Service {8854095900} ❤️VVIP ROCKY Call Girl in Dehradun U...
Dehradun Call Girls Service {8854095900} ❤️VVIP ROCKY Call Girl in Dehradun U...Dehradun Call Girls Service {8854095900} ❤️VVIP ROCKY Call Girl in Dehradun U...
Dehradun Call Girls Service {8854095900} ❤️VVIP ROCKY Call Girl in Dehradun U...
 
tongue disease lecture Dr Assadawy legacy
tongue disease lecture Dr Assadawy legacytongue disease lecture Dr Assadawy legacy
tongue disease lecture Dr Assadawy legacy
 
Kolkata Call Girls Service ❤️🍑 9xx000xx09 👄🫦 Independent Escort Service Kolka...
Kolkata Call Girls Service ❤️🍑 9xx000xx09 👄🫦 Independent Escort Service Kolka...Kolkata Call Girls Service ❤️🍑 9xx000xx09 👄🫦 Independent Escort Service Kolka...
Kolkata Call Girls Service ❤️🍑 9xx000xx09 👄🫦 Independent Escort Service Kolka...
 
Call Girls Mussoorie Just Call 8854095900 Top Class Call Girl Service Available
Call Girls Mussoorie Just Call 8854095900 Top Class Call Girl Service AvailableCall Girls Mussoorie Just Call 8854095900 Top Class Call Girl Service Available
Call Girls Mussoorie Just Call 8854095900 Top Class Call Girl Service Available
 
Call Girl In Chandigarh 📞9809698092📞 Just📲 Call Inaaya Chandigarh Call Girls ...
Call Girl In Chandigarh 📞9809698092📞 Just📲 Call Inaaya Chandigarh Call Girls ...Call Girl In Chandigarh 📞9809698092📞 Just📲 Call Inaaya Chandigarh Call Girls ...
Call Girl In Chandigarh 📞9809698092📞 Just📲 Call Inaaya Chandigarh Call Girls ...
 
Call Girls Rishikesh Just Call 9667172968 Top Class Call Girl Service Available
Call Girls Rishikesh Just Call 9667172968 Top Class Call Girl Service AvailableCall Girls Rishikesh Just Call 9667172968 Top Class Call Girl Service Available
Call Girls Rishikesh Just Call 9667172968 Top Class Call Girl Service Available
 
Call Girls in Lucknow Just Call 👉👉8630512678 Top Class Call Girl Service Avai...
Call Girls in Lucknow Just Call 👉👉8630512678 Top Class Call Girl Service Avai...Call Girls in Lucknow Just Call 👉👉8630512678 Top Class Call Girl Service Avai...
Call Girls in Lucknow Just Call 👉👉8630512678 Top Class Call Girl Service Avai...
 
❤️Amritsar Escorts Service☎️9815674956☎️ Call Girl service in Amritsar☎️ Amri...
❤️Amritsar Escorts Service☎️9815674956☎️ Call Girl service in Amritsar☎️ Amri...❤️Amritsar Escorts Service☎️9815674956☎️ Call Girl service in Amritsar☎️ Amri...
❤️Amritsar Escorts Service☎️9815674956☎️ Call Girl service in Amritsar☎️ Amri...
 
Premium Call Girls Dehradun {8854095900} ❤️VVIP ANJU Call Girls in Dehradun U...
Premium Call Girls Dehradun {8854095900} ❤️VVIP ANJU Call Girls in Dehradun U...Premium Call Girls Dehradun {8854095900} ❤️VVIP ANJU Call Girls in Dehradun U...
Premium Call Girls Dehradun {8854095900} ❤️VVIP ANJU Call Girls in Dehradun U...
 
Kolkata Call Girls Naktala 💯Call Us 🔝 8005736733 🔝 💃 Top Class Call Girl Se...
Kolkata Call Girls Naktala  💯Call Us 🔝 8005736733 🔝 💃  Top Class Call Girl Se...Kolkata Call Girls Naktala  💯Call Us 🔝 8005736733 🔝 💃  Top Class Call Girl Se...
Kolkata Call Girls Naktala 💯Call Us 🔝 8005736733 🔝 💃 Top Class Call Girl Se...
 
Gastric Cancer: Сlinical Implementation of Artificial Intelligence, Synergeti...
Gastric Cancer: Сlinical Implementation of Artificial Intelligence, Synergeti...Gastric Cancer: Сlinical Implementation of Artificial Intelligence, Synergeti...
Gastric Cancer: Сlinical Implementation of Artificial Intelligence, Synergeti...
 
Chandigarh Call Girls Service ❤️🍑 9809698092 👄🫦Independent Escort Service Cha...
Chandigarh Call Girls Service ❤️🍑 9809698092 👄🫦Independent Escort Service Cha...Chandigarh Call Girls Service ❤️🍑 9809698092 👄🫦Independent Escort Service Cha...
Chandigarh Call Girls Service ❤️🍑 9809698092 👄🫦Independent Escort Service Cha...
 
Bhawanipatna Call Girls 📞9332606886 Call Girls in Bhawanipatna Escorts servic...
Bhawanipatna Call Girls 📞9332606886 Call Girls in Bhawanipatna Escorts servic...Bhawanipatna Call Girls 📞9332606886 Call Girls in Bhawanipatna Escorts servic...
Bhawanipatna Call Girls 📞9332606886 Call Girls in Bhawanipatna Escorts servic...
 
Cardiac Output, Venous Return, and Their Regulation
Cardiac Output, Venous Return, and Their RegulationCardiac Output, Venous Return, and Their Regulation
Cardiac Output, Venous Return, and Their Regulation
 
Cara Menggugurkan Kandungan Dengan Cepat Selesai Dalam 24 Jam Secara Alami Bu...
Cara Menggugurkan Kandungan Dengan Cepat Selesai Dalam 24 Jam Secara Alami Bu...Cara Menggugurkan Kandungan Dengan Cepat Selesai Dalam 24 Jam Secara Alami Bu...
Cara Menggugurkan Kandungan Dengan Cepat Selesai Dalam 24 Jam Secara Alami Bu...
 
Ahmedabad Call Girls Book Now 9630942363 Top Class Ahmedabad Escort Service A...
Ahmedabad Call Girls Book Now 9630942363 Top Class Ahmedabad Escort Service A...Ahmedabad Call Girls Book Now 9630942363 Top Class Ahmedabad Escort Service A...
Ahmedabad Call Girls Book Now 9630942363 Top Class Ahmedabad Escort Service A...
 
Call Girls in Lucknow Just Call 👉👉 8875999948 Top Class Call Girl Service Ava...
Call Girls in Lucknow Just Call 👉👉 8875999948 Top Class Call Girl Service Ava...Call Girls in Lucknow Just Call 👉👉 8875999948 Top Class Call Girl Service Ava...
Call Girls in Lucknow Just Call 👉👉 8875999948 Top Class Call Girl Service Ava...
 
Call Girls Bangalore - 450+ Call Girl Cash Payment 💯Call Us 🔝 6378878445 🔝 💃 ...
Call Girls Bangalore - 450+ Call Girl Cash Payment 💯Call Us 🔝 6378878445 🔝 💃 ...Call Girls Bangalore - 450+ Call Girl Cash Payment 💯Call Us 🔝 6378878445 🔝 💃 ...
Call Girls Bangalore - 450+ Call Girl Cash Payment 💯Call Us 🔝 6378878445 🔝 💃 ...
 
Call Girl in Chennai | Whatsapp No 📞 7427069034 📞 VIP Escorts Service Availab...
Call Girl in Chennai | Whatsapp No 📞 7427069034 📞 VIP Escorts Service Availab...Call Girl in Chennai | Whatsapp No 📞 7427069034 📞 VIP Escorts Service Availab...
Call Girl in Chennai | Whatsapp No 📞 7427069034 📞 VIP Escorts Service Availab...
 
Exclusive Call Girls Bangalore {7304373326} ❤️VVIP POOJA Call Girls in Bangal...
Exclusive Call Girls Bangalore {7304373326} ❤️VVIP POOJA Call Girls in Bangal...Exclusive Call Girls Bangalore {7304373326} ❤️VVIP POOJA Call Girls in Bangal...
Exclusive Call Girls Bangalore {7304373326} ❤️VVIP POOJA Call Girls in Bangal...
 

Well Baby Nursery Guidelines

  • 1. Author: Sitratullah O Maiyegun MD Editors: Namrata Singh MD Maria Villanos MD Jesus Peinado MD Ashish Loomba MD Well baby Nursery Director: Carmen Prieto MD 07/03/13 1S O MAIYEGUN MD
  • 2.  The guidelines do not indicate an exclusive course of treatment or serve as a standard of medical care  Appropriate management can be modified according to individual circumstances  Please apply evidence based medicine as appropriate 07/03/13 2S O MAIYEGUN MD
  • 3.  Evaluate well newborns with history, physical exam and routine screening procedures, and provide preventive counseling and intervention as indicated  Manage breast and formula feeding in the newborn period  Evaluate and manage common conditions and infections in the normal newborn 07/03/13S O MAIYEGUN MD 3
  • 4.  Recognize and manage jaundice in the newborn period  Provide anticipatory counseling at nursery discharge that relates to newborn behavior, family adjustment, injury prevention, and access to medical services 07/03/13S O MAIYEGUN MD 4
  • 5.  Wash hands before and after examining any infant  All babies must be examined within 24 hours of birth  All admission orders (entered by nurses) must be signed  Maternal prenatal lab results and GBS status, and mother and infant’s blood types  HIV, RPR and Hep B status must be updated within 12 hours of delivery    07/03/13S O MAIYEGUN MD 5
  • 6.  Admission and discharge diagnoses to be documented with problem lists  Update maternal labs prior to discharges  Any abnormal results reported to the intern must be reported to the senior and/or faculty 07/03/13S O MAIYEGUN MD 6
  • 7.  Birth weight < 2250 gms  Gestational age < 35 wks  Apgar score of <5 at 5 mins  Prolonged period of abnormal transition (more than 4 hrs )  Initial Se. Glucose <30 mg% (after ISTAT)  Maternal chorio detected in L&D  Initial rectal temp 102 F or more  Unstable baby in L&D or OR 07/03/13 7S O MAIYEGUN MD
  • 8.  All babies will be placed skin-to-skin with mom for breastfeeding for as long as they are stable  Nursing procedures and further assessment will be done while with mom  Babies will be transferred to room with mom from L&D 07/03/13S O MAIYEGUN MD 8
  • 9.  Babies of diabetics and moms on magnesium will also be placed skin-to-skin unless otherwise symptomatic or per pediatrician order  After skin-to-skin they will go to the NBN for further assessment or stay with mom if mom is stable  Stable C/S babies stay with the relatives in OR /L&D till mom is able to handle the baby 07/03/13S O MAIYEGUN MD 9
  • 10.  Maternal history of diabetes, Fever  PROM >18hours (CDC, AAP)  <37wks  Weight ≥3800 gms and ≥2500gms  LGA >90th percentile or SGA/IUGR < 10th percentile for weight 07/03/13S O MAIYEGUN MD 10
  • 11.  Blood glucose within 30mins-1hour of admission in high risk babies  Peripheral hematocrit: in high risk babies  Eye prophylaxis with 0.5% erythromycin ophthalmic ointment  Vitamin K 1mg IM X1  Hepatitis B vaccine X1( after consent)  Cord blood studies if mother is O+ or Rh (-) 07/03/13 11S O MAIYEGUN MD
  • 12.  Radiant warmer in the nursery until stable to transfer to mom’s room  If needed , formula feeds need to be prescribed ( Baby-friendly policy)  Normal delivery24hours observation if all discharge criteria fulfilled  If risk factors  48hours  C/S delivery  observe for 48hrs 07/03/13 12S O MAIYEGUN MD
  • 13.  Breastfed and formula fed infants should be supplemented with 400 IU/day of vitamin D beginning in the first few days of life  Supplementation should be continued unless the infant is weaned to at least 1 L/day vitamin D–fortified formula (1 or 2 months)  1liter of regular infant formula(406 IU of Vitamin D) 07/03/13S O MAIYEGUN MD 13
  • 14.  Newborn hearing screen before discharge  If failed Algo X2Refer for BAER  Newborn screen at 24hrs of life  Jaundice meter reading upon admission and q shift until discharge 07/03/13 14S O MAIYEGUN MD
  • 15.  History  Adequate prenatal care≥ 4 visits  Maternal age > 17years  No maternal drug use  Mother not A1or A2 diabetic  Mother not GBS+ or Chlamydia +  Mother not RPR+, HIV +, HepB/C + 07/03/13 15S O MAIYEGUN MD
  • 16.  Delivery  Vaginal delivery in the hospital  Rupture of Membranes < 18hours (CDC)  No maternal temperature >101 or concern regarding chorioamnionitis  Apgar score at 5minutes at least 7 07/03/13 16S O MAIYEGUN MD
  • 17.  Examination  Gestational age of at least 37weeks  Baby is not on 24-hour glucose series (LGA, SGA or initial hypoglycemia)  No physical findings that requires further monitoring  Vital signs are documented as being within normalranges and stable for the last 12 hours preceding discharge 07/03/13 17S O MAIYEGUN MD
  • 18.  No vital signs abnomalities: No Temp instability, RR<60, HR 100-160, axillary temperature of 36.5°C to 37.4°C (97.7°F to 99.3°F)  No Jaundice in the first 24hrs  The clinical significance of jaundice, if present before discharge,has been determined, and appropriate managementand/or follow-upplans have been put in place 07/03/13S O MAIYEGUN MD 18
  • 19.  No Jaundice in the first 24hrs  The clinical significance of jaundice, if present before discharge,has been determined, and appropriate managementand/or follow-upplans have been put in place 07/03/13S O MAIYEGUN MD 19
  • 20.  No history of poor feeding or emesis  Able to coordinate sucking,swallowing, and breathing while feeding  Normal voiding and stooling pattern 07/03/13 20S O MAIYEGUN MD
  • 21.  Labs  No Glucose issues during the first 24hrs  Bilirubin in the normal range as per risks  Maternal RPR, HIV, HBsAG status known  If Rubella non-immune inform OB resident to make sure mom is vaccinated PTD  No ABO setup, baby is Coombs negative  Algo hearing test done (otoacoustic emission) done 07/03/13S O MAIYEGUN MD 21
  • 22.  Psychosocial  At least 2 successful feedings without the help of nurses (lactation consult if needed)  Good maternal-baby bonding, no maternal depression  No nursing concerns 07/03/13 22S O MAIYEGUN MD
  • 23. ◦ Cord, skin, and genitalcare for infant ◦ Ability to recognize signs of illness and common infant problems,particularly jaundice ◦ Proper infantsafety (proper use of a car safety seat andsupine positioningfor sleeping) 07/03/13S O MAIYEGUN MD 23
  • 24.  Teenage mothers <17 yrs with or without prenatal care  Teenage mothers <17 yrs without a family or support system in place or other specified problems (i.e. depression, lack of planning, bonding) 07/03/13 24S O MAIYEGUN MD
  • 25.  Mothers with substance abuse (present + screen or previous)  Mother with previous hx of post-partum depression  Discharge against medical advice 07/03/13S O MAIYEGUN MD 25
  • 26.  Early discharges < 48 hours follow-up within 1 to 2 days or 72 hours (earlier visit not possible)  If no risk factors, clinically well d/c after 24 hours  If risk factors are present, clinically not well appearing, required limited evaluation d/c after 48 hours 07/03/13S O MAIYEGUN MD 26
  • 28.  Problem- ◦ Any deviation from completely normal external male or female genitalia  Clitoral enlargement (> 1.0 cm)  Labioscrotal fusion of any degree  Hypospadias (penoscrotal, scrotal or perineal ) 07/03/13 28S O MAIYEGUN MD
  • 29.  Any degree of hypospadias with unilateral or bilateral cryptorchidism  Micropenis (stretched length < 2.5 cm)  Bilateral cryptorchidism ( with other anomalies ) 07/03/13S O MAIYEGUN MD 29
  • 30. 30  Please do not include prominent labia minora in a preterm  Check the gestational age!!!!!!! 3/2/2011S O MAIYEGUN MD 07/03/13 30S O MAIYEGUN MD
  • 31.  First degree (glandular): urethral meatus opens on the underside of the glans penis in about 50– 75% of cases  Second degree(Midshaft) :when the urethra opens on the shaft  Third degree (penoscrotal and perineal): when the urethra opens on the perineum) occur in up to 20 and 30% of cases respectively 07/03/13S O MAIYEGUN MD 31
  • 32. 07/03/13 32S O MAIYEGUN MD
  • 33. 07/03/13 33S O MAIYEGUN MD
  • 34.  Severe degrees are more likely to be associated with chordee  The phallus is incompletely separated from the perineum or is still tethered downwards by connective tissue, or with undescended testes (cryptorchidism) 07/03/13S O MAIYEGUN MD 34
  • 35. 35  Hypospadias ( 1st and 2nd degree) with palpable testicles  Observe and referral to urologist outpt  No need for US kidneys (develops from genital tubercles)  Advice against circumcision (prepuce for repair) 3/2/2011S O MAIYEGUN MD 07/03/13 35S O MAIYEGUN MD
  • 36. 07/03/13S O MAIYEGUN MD 36 CHORDEE
  • 37.  Plan-  No gender assignment until after endocrine consult ◦ As soon as possible after birth  U/S abdomen ( uterus, testes, adrenals)  Karyotype  17-OH progesterone  Electrolytes BMP ( virilization ) 07/03/13 37S O MAIYEGUN MD
  • 38.  LH, FSH, Testostorone, dihydrotestostrone, DHT,  Peds endo consult stat !!!!  Parent education and counseling !!!! 07/03/13S O MAIYEGUN MD 38
  • 39.  Problem- ◦ Initial HCT of <40 mg% (spun Hct) ◦ Pale newborn  Plan- ◦ Do PE & check for symptoms ( splenomegaly, tachypnea, tachycardia, shock, CHF, murmur ) —if present consult attending 07/03/13 39S O MAIYEGUN MD
  • 40.  Plan- ◦ Check maternal history  Severe prenatal anemia  Perinatal blood loss  3rd trimester bleeding  Maternal blood type & antibody screen  Abruptio placenta or placenta previa 07/03/13 40S O MAIYEGUN MD
  • 41. ◦ Check birth history  Asphyxia & Apgar scores  Delivery method & special circumstances  Plan- ◦ Lab w/u-  CBC & peripheral smear  Retics count, fractionated bili  Blood type & Coombs 07/03/13S O MAIYEGUN MD 41
  • 42.  Plan-  Maternal Kleihauer Betke test (request OB resident to order)  Repeat HCT in 12-24 hrs – if decreasing notify attending ( may need head &/or abdominal US- liver/adrenal hemorrhage) 07/03/13 42S O MAIYEGUN MD
  • 44.  Problem- ◦ Blood streaked diaper with normal stool  Plan- ◦ Check for- ◦ Clinical activity  Small laceration/fissure or area of irritation in anal area  Abdominal distention  Other symptoms (poor feeding , vomiting etc.) 07/03/13 44S O MAIYEGUN MD
  • 45.  Plan- ◦ If no fissure-  Stool for occult blood  Stool for culture, WBC and rotavirus  Stool for reducing substance  **Apt test (send-out) take a while to get result  If maternal blood – f/u  If fetal blood – discuss with attending  Make sure Vit K has been given 07/03/13 45S O MAIYEGUN MD
  • 46.  CBC with diff : ◦ inflammatory response ◦ thrombocytopenia ◦ anemia  If abdominal distention  Stat KUB  Stat CBC & CRP  Discuss with attending 07/03/13S O MAIYEGUN MD 46
  • 47.  Problem- ◦ Infant not moving arm ; arm & held limply extended to the side with hand flexed ◦ Erb-Duchenne palsy (C5 - C6) ◦ Klumpke’ s paralysis ( C7-8 , T1)  Plan – ◦ Examine infant-  Clavicular crepitus  Presence of grasp ( absent in Klumpke’s)  Assoc. resp distress ( Erb’s) ; Horners synd ( Klumpke’s) 07/03/13 47S O MAIYEGUN MD
  • 48. 07/03/13 48S O MAIYEGUN MD
  • 49.  Plan- ◦ Cxr with clavicles  If clavicle fractured –immobilize arm  F/u outpt with Orthopedics ◦ Physical Tx consult as outpt ◦ Neurology consult as outpt if severe Erb’s palsy 07/03/13 49S O MAIYEGUN MD
  • 50. 07/03/13 50S O MAIYEGUN MD
  • 51.  HR=85-160bpm (0-24hr) 100-175bpm(1-7days) or > 2SD above the mean for age, asleep or awake  HR persistently < 80-100/min(awake),<70- 90/min(asleep) and/or dropped beats  Dropped or skipped beats 07/03/13SOMAIYEGUN MD 5107/03/13 51S O MAIYEGUN MD
  • 52.  Plans:  Maternal Hx of SLE  Ionized Ca with BMP(K+)  EKG and CXR (pneumothorax/heart shape)  Cardiac consult  Echo after discussion with the attending 07/03/13SOMAIYEGUN MD 5207/03/13 52S O MAIYEGUN MD
  • 54. 54  Molding of the head  Crosses the suture lines  Subcutaneous soft tissue swelling  Poorly defined margins  Usually resolves over the first few days  Observation SOMAIYEGUN MD07/03/13 54S O MAIYEGUN MD
  • 55. Subperiosteal hemorrhage ◦Unilateral or bilateral, most commonly over parietal bone, rarely the occipital bone ◦Firm swelling or fluctuant ◦Limited by suture lines/ does not cross the suture lines 07/03/13 55S O MAIYEGUN MD
  • 56.  Plan- ◦ Obtain delivery history: SVD, forceps and vacuum ◦ Check for jaundice q 12hrs (J-meter) ◦ Discuss with mother- reassurance  May be felt till 3 mos of age & may calcify 07/03/13S O MAIYEGUN MD 56
  • 57. 07/03/13 57S O MAIYEGUN MD
  • 58. 07/03/13 58S O MAIYEGUN MD
  • 59. 07/03/13 59S O MAIYEGUN MD
  • 60. 07/03/13 60S O MAIYEGUN MD
  • 61.  If large or bilateral, CNS signs, difficult delivery, depressed skull fracture AP & Lat skull X- Rays or CT head( discuss)  If Hct dropped rapidly inform attending  US head or CT head to r/o ICH/IVH ◦ PT/PTT, CBC (Immune thrombocytopenia) ◦ If signs of shock IMCN 07/03/13 61S O MAIYEGUN MD
  • 62.  There is increased risk of intracranial hemorrhage among infants delivered by vacuum extraction or forceps or unassisted vaginal deliveries (or prolonged labor )  ICH: subdural or cerebral hemorrhage, intraventricular hemorrhage, subarachnoid hemorrhage 07/03/13 62S O MAIYEGUN MD
  • 63.  Problem – ◦ Shoulder dystocia @ birth ◦ Tenderness , swelling over clavicle ◦ Crepitus over clavicle ◦ Decreased movement of arm  Plan— ◦ X-rays of clavicle 07/03/13 63S O MAIYEGUN MD
  • 64.  It may be asymptomatic  Generally, there is no treatment other than lifting the child gently to prevent discomfort  The arm on the affected side may be immobilized by pinning the sleeve to the clothes (Swaddle / immobilize)  Orthopedic referral as out-patient, if severe as in-patient ( discuss with attending) 07/03/13S O MAIYEGUN MD 64
  • 66.  DD: partial dislocation of the elbow, Erb palsy, fractured humerus  Reassure mother and inform about subsequent callus formation  Full recovery usually occurs without treatment 07/03/13S O MAIYEGUN MD 66
  • 67.  Problem- ◦ Abnormal buccal cavity ◦ Maybe unilateral , bilateral or midline ◦ Maybe mild , severe or partial ◦ Maybe submucosal with bifid uvula  Plan- ◦ Obtain fam hx ,prenatal hx (meds) ◦ If midline  head U/S to r/o holoprosencephaly 07/03/13 67S O MAIYEGUN MD
  • 68. 07/03/13 68S O MAIYEGUN MD
  • 69.  Plan- ◦ Assess feeding  Special nipple- Haberman nipple  No bottle propping  Feed in upright position  Occupation therapy (OT) consult  Plastic surgery consult as outpatient  Genetics consult as outpatient if indicated 07/03/13 69S O MAIYEGUN MD
  • 70.  Haberman nipple for feeding 07/03/13 70S O MAIYEGUN MD
  • 71.  Problem-fixed or flexible (positional) ◦ Forefoot in fixed adduction ◦ Calcaneal tendon is shortened ◦ Foot is inverted with plantar flexion ◦ Inability to correct itself by stroking the outside & inside of foot (fixed)  Plan-if fixed ◦ Check hips ◦ Ortho consult as in-patient (X-ray, stretching and serial casting) ◦ Discuss with mother 07/03/13 71S O MAIYEGUN MD
  • 72.  If flexible (positional) , reassurance and passive stretching by mother q prn  Any orthopedic abnormalities, discuss with attending prior to ortho consult 07/03/13 72S O MAIYEGUN MD
  • 73. 07/03/13 73S O MAIYEGUN MD
  • 74.  Eye prophylaxis with 0.5% erythromycin ophthalmic ointment  It is not effective in preventing neonatal chlamydial conjunctivitis or extraocular infection  Effective for prevention of gonococcal ophthalmia 07/03/13 74S O MAIYEGUN MD
  • 75.  Problem- ◦ Newborn with eye discharge ◦ Can be unilateral or bilateral ◦ Possible periorbital edema ◦ Eyelids may be erythematous or appear glued shut 07/03/13 75S O MAIYEGUN MD
  • 76.  Plan- ◦ Maternal hx of GC , Chlamydia , Herpes ◦ Delivery hx –( Erthromycin ointment application , maternal vaginal discharge , PROM) ◦ Evaluate timing of onset , amount ,color, consistency, tendency to return ◦ Plans;  Gram stain and culture 07/03/13 76S O MAIYEGUN MD
  • 77.  Plan- ◦ If Gram stain positive for bacteria or PMN’s , discuss with attending ◦ Cleanse eyes with sterile water  Note— ◦ Chemical conjunctivitis—  Develops within hours after birth & resolves in 36-48 hours  Gram stain negative but PMN’s are present 07/03/13 77S O MAIYEGUN MD
  • 78. ◦ GC conjunctivitis–  Presents usually 1-4 days after birth  Can present within a few hours after birth  Lid edema , copious purulent exudate , chemosis , clouding of the cornea 07/03/13 78S O MAIYEGUN MD
  • 79. Gm stain  PMN’s & intracellular Gm negative diplococci Tx – Inform attending for transfer to IMCN for Ceftriaxone and workup for sepsis Reportable to Department of Health within 72hours 07/03/13S O MAIYEGUN MD 79
  • 80.  Ceftriaxone (25-50 mg/kg, intravenously or intramuscularly, not to exceed 125 mg) given x 1  Cefotaxime x1 (100mg/kg IV or IM) is recommended for infants with hyperbilirubinemia  Infants with gonococcal ophthalmia should receive eye irrigations with saline solution immediately and at frequent intervals until the discharge is eliminated 07/03/13 80S O MAIYEGUN MD
  • 81.  Topical antimicrobial treatment alone is inadequate and is unnecessary when recommended systemic antimicrobial treatment is given 07/03/13 81S O MAIYEGUN MD
  • 82.  Hospitalized and evaluated for disseminated infection (sepsis, arthritis, meningitis)  Recommended therapy for arthritis and septicemia is ceftriaxone or cefotaxime for 7 days, if meningitis is document treatment should be continued for a total of 10 to 14 days 07/03/13S O MAIYEGUN MD 82
  • 83. ◦ If late onset > 1st 24 hours of life or suspected causes other than reaction to eye prophylaxis  Gram stain & culture ◦ Chlamydia conjunctivitis—  Presents 5-14 days after birth  Purulent discharge, eyelid edema & conjunctival inflammation 07/03/13S O MAIYEGUN MD 83
  • 84.  Conjunctival scraping for Chlamydia: Infectious disease consult  Reportable to Department of Health within 72hours 07/03/13S O MAIYEGUN MD 84
  • 85. If mom is Chlamydia positive and with or without treatment Baby is asymptomatic  no treatment FU in out-pt for signs of infection  Prompt treatment of mother and her sexual partner(s) 07/03/13S O MAIYEGUN MD 85
  • 86.  Oral azithromycin for 5 days or erythromycin base or ethylsuccinate for 14 days + erythromycin eye ointment  If unstable and severe respiratory  IV erythromycin after evaluation for sepsis in IMCN  Infantile hypertrophic pyloric stenosis (IHPS) in < 6weeks (erythromycin) 07/03/13 86S O MAIYEGUN MD
  • 87.  Problem— ◦ Infant with soft or ping-pong skull ◦ Usually over temporo-parietal region & along suture lines ◦ Causes-  Hydrocephalus ,OI ,syphilis, rickets , hypervitaminosis A , normal variation (sagittal suture craniotabes in premies) 07/03/13 87S O MAIYEGUN MD
  • 88.  Plan— ◦ Maternal Hx– infections , medications , family history ◦ Transilluminate skull ◦ Head US & skull X-rays – if needed ◦ Check maternal RPR – if positive follow syphilis protocol 07/03/13 88S O MAIYEGUN MD
  • 90. 90  Problem- ◦ Hip “clunk” ◦ Positive Barlow or Ortolani sign ◦ Unequal thigh/gluteal creases or leg lengths ◦ Strong family history ◦ Breech presentation SOMAIYEGUN MD 07/03/13 90S O MAIYEGUN MD
  • 91.  Plan- ◦ If “click” present  re-examine @ D/C ◦ If “click” & + strong family history Ortho consult ◦ If “clunk” present Ortho consult ◦ U/S hip if needed, will be ordered or advised by orthopedics ◦ Discuss with mother ◦ FU with PCP ◦ Only ClickRe-check hips in 2 weeks(AAP) SOMAIYEGUN MD07/03/13 91S O MAIYEGUN MD
  • 92.  Breech with abnormal click/clunk prior to discharge Ortho consult or otherwise U/S hip at 4-6 weeks of age and/or radiographic imaging at 4-6 mos (AAP)  US hip screening of all breech newborns will not eliminate the possibility of later acetabular dysplasia (AAP) 07/03/13 92S O MAIYEGUN MD
  • 93.  Problem— ◦ 2 abnormal stools in an 8 hour period ◦ Numerous large watery , foul smelling stools with blood , mucous  Plan— ◦ Examine baby & review vitals ◦ Look at stool ◦ Send stool for reducing substances, leucocytes, RBC & culture, rotavirus 07/03/13 93S O MAIYEGUN MD
  • 94. 94  If reducing substance positive(+)  switch to soy based formula/ lactose free milk ◦ If stool is watery++ sent stool for electrolytes ◦ BMP ◦ Suspect chloride diarrhea in mom with hx of polyhydramnios 3/2/2011S O MAIYEGUN MD 07/03/13 94S O MAIYEGUN MD
  • 95.  Plan— ◦ If baby looks sick , abnormal vitals , abdominal distention get KUB stat , CBC , CRP, BMP ◦ Inform attending ◦ Discuss normal variations in stooling patterns with mother 07/03/13 95S O MAIYEGUN MD
  • 96.  Breast fed stools-frequent, without form, may be mucousy; affected by maternal diet ( fruit , laxatives ,medications)  If starvation present may be frequent , small quantity, dark green  Stools can be less frequent & pasty 07/03/13S O MAIYEGUN MD 96
  • 97. ◦ Discuss normal variations in stooling patterns with mother  Breast fed stools-frequent, without form ,may be mucousy; affected by maternal diet ( fruit , laxatives ,medications)  If starvation present may be frequent , small quantity, dark green  Stools can be less frequent & pasty 07/03/13S O MAIYEGUN MD 97
  • 98. 07/03/13 98S O MAIYEGUN MD
  • 99.  3-8% of NB  The possibility of occult spinal dysraphism (OSD) is more likely if above the gluteal cleft (truly sacral in location) because they are more likely to be contiguous with the dura  Within the gluteal fold: less likely to be contiguous with the dura and are much more likely to be a normal variant 07/03/13 99S O MAIYEGUN MD
  • 100.  Simple or low risk :  Position – within the gluteal fold or coccygeal position  Single dimple  < 5 mm diameter  Base of dimple is visible 07/03/13 100S O MAIYEGUN MD
  • 101.  Dimple is oriented straight down (i.e. caudal) not cephalically (i.e. toward the head)  No other dermal abnormalities or masses  Distance < 2.5 cm from anus  Normal neurological examination 07/03/13S O MAIYEGUN MD 101
  • 102.  Difficult to clearly distinguish all variations consider the individual circumstances  Plan: U/S spine 3/2/2011 102S O MAIYEGUN MD 07/03/13 102S O MAIYEGUN MD
  • 103.  Midline / vertebra appearance of significant tuft of hair ,hemangioma or nevus  Plan: U/S spine 07/03/13 103S O MAIYEGUN MD
  • 104.  Discharge diagnosis is very important  Make an assessment regarding what observation and treatment the infant needs and discuss findings with the parents  Explain to the parent(s) of the possible consequences for their infant if they leave e.g sepsis, jaundice  Explain the need for FU in 1 or 2 days and ER warnings  Consult with the social worker (SW) 07/03/13 104S O MAIYEGUN MD
  • 105.  If medical diagnosis or concerns exist which may result in immediate harm to the infant  Remind parent(s) that their action is contrary to the welfare of their infant and that Department for Child Protective Services (CPS) will be notified  Child can be kept in the holding nursery if mother wants to go home 07/03/13 105S O MAIYEGUN MD
  • 106.  Consult with the social worker (SW)  They will make an assessment and consult with CPS or Crisis Care (after hours/weekends) as necessary  CPS hold statutory powers and have the authority under the Children and Community Services Act 2004 to protect the welfare, care and protection of children 07/03/13 106S O MAIYEGUN MD
  • 107. 07/03/13 107S O MAIYEGUN MD
  • 108.  Infant with features of Down syndrome ◦ Talk to the family (mom) ◦ No d/c prior to 48 hrs of age ◦ Evaluate feeding / vomiting (duodenal atresia) ◦ Glucose series (hypoglycemia) ◦ CBC with diff & platelets(polycythemia, leukemoid reaction or leukemia) ◦ Ensure good follow-up 07/03/13 108S O MAIYEGUN MD
  • 109.  Karyotype (with informed consent) ◦ Maternal and family history ◦ Echocardiogram prior to discharge ◦ Cardiac consult as needed ◦ Genetics consult as out-patient 07/03/13 109S O MAIYEGUN MD
  • 111.  Problem— ◦ Grossly abnormal ears ◦ Significant low set and posteriorly rotated ears ◦ Incomplete auricle ◦ No visible ear (anotia) ◦ Multiple significant ear tags (pre-auricular tags) ◦ Pre-auricular sinus/pit with a blind end is not included 07/03/13 111S O MAIYEGUN MD
  • 112. 07/03/13 112S O MAIYEGUN MD
  • 113. 07/03/13 113S O MAIYEGUN MD
  • 114.  Plan— ◦ Strong family history of similar defects ◦ Hearing test (ALGO 2)  if failed schedule for BAER test ◦ Renal US to r/o abnormalities after discussing with faculty ◦ Look for other dysmorphic features and associations 07/03/13 114S O MAIYEGUN MD
  • 115.  C coloboma  H congenital heart defects  A choanal atresia  R retardation of growth and development/ CNS  G genitourinary anomalies  E ear and/or auditory anomalies 07/03/13 115S O MAIYEGUN MD
  • 116.  Newborn with copious oral secretions and episodes of coughing, choking, and cyanosis  Hx of pregnancy complicated by polyhydramnios  Plans: place an orogastric suction catheter and obtain a chest radiograph 07/03/13 116S O MAIYEGUN MD
  • 117.  VACTERL association  V Vertebral or Ventriculoseptal defects  A Anal atresia  C Cardiac anomalies  T/E Tracheoesophageal fistula/ esophageal atresia  R Radial dysplasia / Renal anomaly  L limbs 3/2/2011 117S O MAIYEGUN MD 07/03/13 117S O MAIYEGUN MD
  • 118. F 3/2/2011 118S O MAIYEGUN MD 07/03/13 118S O MAIYEGUN MD
  • 119.  Problem— ◦ Large anterior fontanel (>5 x 5 cm) with/without large posterior fontanel ( > 2 cm) ◦ Open metopic suture ◦ Open coronal suture  Plan—  Check HC yourself ; neurologic exam  T4 & TSH ; head sono ; discuss with attending 07/03/13 119S O MAIYEGUN MD
  • 120. 07/03/13 120S O MAIYEGUN MD
  • 121. 07/03/13 121S O MAIYEGUN MD
  • 123. ◦ GBS+ mother with 1 dose of intrapartum abx < 4hrs PTD  CBC and CRP at 24 hrs ◦ GBS+ mother with at least 1 dose of intrapartun abx > 4hrs PTD asymptomatic observe for 48hrs ◦ No discharge prior to 48 hrs of age  If baby is unstable  CBC/+ CRP (if >24hr) stat ± transfer to IMCN as appropriate 07/03/13 123S O MAIYEGUN MD
  • 124. ◦ PROM >18hrs (+ intrapartum abx given to mum), if stable CBC & CRP at 24 hrs and re-evaluate ◦ PROM >18hrs (no intrapartum abx given to mum) CBC at birth and CBC & CRP at 24 hrs and re-evaluate ◦ No discharge prior to 48 hrs of age 07/03/13 124S O MAIYEGUN MD
  • 125. ◦ GBS (+)mum, good PNC, term ≥37wks, SVD ◦ Adequate intrapartum antibiotic prophylaxis (IAP) given ◦ Asymptomatic baby ◦ Mom is able to comply with home instruction for observation ◦ Can be discharged home after 24hrs if other discharge criteria are met ◦ If discharge criteria are not met  observe for 48hrs 07/03/13 125S O MAIYEGUN MD
  • 126. ◦ Intrapartum antibiotic prophylaxis (IAP) ◦ Adequate if penicillin, ampicillin or cefazolin is given at the proper doses for four or more hours prior to delivery ◦ Duration of IAP shorter than four hours and all other antimicrobial regimens,  clindamycin  Vancomycin ◦ are considered as inadequate because no data regarding efficacy are available 07/03/13 126S O MAIYEGUN MD
  • 127.  Penicillin and ampicillin rapidlyachieve therapeutic levels in the fetal circulation and requirethree hours to achieve therapeutic levels in amniotic fluid  Cefazolin has similar pharmacokinetics and is the preferredagent for IAP in penicillin allergic women with no history ofanaphylaxis, angioedema, respiratory distress or urticaria 07/03/13 127S O MAIYEGUN MD
  • 128.  Problem: ◦ No documented PNC or GBS unknown ◦ Prenatal care at lay midwife maternity center ◦ Less than 4 visits starting later than 28th week of gestation  Plan— ◦ Check perinatally drawn maternal labs and please document prior to D/C 07/03/13 128S O MAIYEGUN MD
  • 129.  If baby is stable: NO screening with CBC and CRP at 24 hours  Observe for 48hour in the hospital  If baby symptomatic at anytime <24hours CBC stat ± transfer to IMCN as appropriate  If symptomatic > 24hours CBC and CRP ± transfer to IMCN as appropriate 3/2/2011 129S O MAIYEGUN MD 07/03/13 129S O MAIYEGUN MD
  • 130. ◦ PROM >18hrs (+ intrapartum abx given to mom), if stable CBC & CRP at 24 hrs and re-evaluate ◦ PROM >18hrs (no intrapartum abx given to mom) CBC at birth and CBC & CRP at 24 hrs and re-evaluate ◦ GBS (–)negative in the hospital and NPC  48hrs observation ◦ No discharge prior to 48 hrs of age 3/2/2011 130S O MAIYEGUN MD 07/03/13 130S O MAIYEGUN MD
  • 131. ◦ Any symptoms  CBC stat or CBC and CRP if >24hrs or transfer to IMCN as appropriate ◦ If labs are grossly abnormal CRP>20 x 2 or CRP >40 X1, WCC>30 or <5, even if clinically stable, discuss with attending for possible transfer to IMCN **48-hour CBC and CRP will be ordered after 24-hour lab is reviewed 07/03/13 131S O MAIYEGUN MD
  • 132.  Problem— ◦ Maternal h/o GC during pregnancy  Plan— ◦ Maternal h/o tx & documentation of cure ◦ If inadequate or no documented test of cure  Ceftriaxone 125 mg I/M x 1 ◦ No discharge prior to 48hrs 07/03/13 132S O MAIYEGUN MD
  • 134.  Problem— ◦ Maternal h/o hepatitis ◦ Mother known HBsAg carrier ◦ Mother @ high risk for being a Hep B carrier ( known or suspect IV drug use , mother from endemic region) 07/03/13 134S O MAIYEGUN MD
  • 135.  Plan— ◦ Verify maternal HBsAg status ◦ If mother positive ◦ Hep B Ig (0.5 cc I/M) within 12 hrs of birth  Hepatitis B vaccine ( 0.5 cc I/M) concurrently @ different site  Breastfeeding is not C/I  ID consult as outpt 07/03/13 135S O MAIYEGUN MD
  • 136.  Plan— ◦ Infants delivered to mothers who are jaundiced ,h/o hepatitis of unknown etiology or who are in a high risk group & have not been screened —  Hep B vaccine (0.5 cc I/M ) within 12 hrs of birth  Verify mothers HBsAg status ; make sure it is drawn. If positive give HBIG 07/03/13 136S O MAIYEGUN MD
  • 137.  Plan— ◦ Mother is Hepatitis C+(anti-HCV-positive )  Order Hep C Ag on baby : (Ig) G antibody enzyme immunoassays for HCV and NAA tests to detect HCV RNA  Assays for IgM to detect early or acute infection are not available  Transmission of HCV by breastfeeding has not been documented 07/03/13 137S O MAIYEGUN MD
  • 138.  Not a contraindication to breastfeeding  Mothers who are HCV positive and choose to breastfeed should consider abstaining if their nipples are cracked or bleeding  F/U with ID as outpt to monitor LFT and anti- HCV 07/03/13 138S O MAIYEGUN MD
  • 139.  Problem— ◦ Mother identified as having vaginal herpes ◦ Previous h/o herpes  Plan— ◦ PE of the baby for rash (vesicles) ◦ Delivery hx-C/S or vaginal ( higher risk) ◦ Instruct mother on care of infant (good hand washing etc) 07/03/13 139S O MAIYEGUN MD
  • 140.  Care of infants born vaginally to a mother with active genital ulcerative lesions. Primary 1st episode of HSV infection or known recurrent lesion or status unknown IMCN in isolation  Care of the infant born via C/S to a mother with active genital ulcerative lesions (primary, recurrent or unknown) esp if onset of labor or ROM > 4hoursIMCN in isolation 07/03/13 140S O MAIYEGUN MD
  • 141.  Care of the infant born to a mother with a history of HSV infection and no active lesions at delivery.  Neither HSV cultures nor empiric therapy with IV Acyclovir are indicated  No isolation necessary  Care of the infant born by C/S (intact membrane) and no active lesions at delivery.  No isolation necessary 07/03/13 141S O MAIYEGUN MD
  • 142.  A mother with herpes labialis or stomatitis should wear a disposable surgical mask when touching her newborn infant until the lesions have crusted and dried  She should not kiss or nuzzle her newborn until lesions have cleared  Herpetic lesions on other skin sites should be covered 07/03/13 142S O MAIYEGUN MD
  • 143.  Problem— ◦ Mother’s HIV is positive  Plan If complete HIV testing is pending after birth and the mom is Elisa positive  Western Blot (WB) still pending then breast feeding should not be initiated until the WB has been reported negative ◦ If mother’s WB is (+)  ◦ if baby is stable, can start PO AZT ◦ if unstable IMCN to start on IV AZT ◦ If mothers WB is (-) ,no issues 07/03/13 143S O MAIYEGUN MD
  • 144.  Plan—  Detailed hx for risk factors  Zidovudine (AZT) must be started 6-12 hours after AZT(8mg/kg/day) PO q6hrs X 6 weeks  Send HIV DNA PCR within the first 48 hours after birth  Cord blood should not be used  ID consult as in-patient 07/03/13 144S O MAIYEGUN MD
  • 145.  Plan—  If hx inconclusive  ID consult  FU on HIV DNA PCR in baby 07/03/13 145S O MAIYEGUN MD
  • 146.  Maternal history of diabetes, Fever  PROM >18hours (CDC, AAP)  <37wks  Weight ≥3800 gms and ≥2500gms  LGA >90th percentile or SGA/IUGR < 10th percentile for weight 07/03/13S O MAIYEGUN MD 146
  • 147.  All high risk babies are screened with blood glucose  Regardless of gestation a serum glucose < 40 mg/dL is hypoglycemia  A serum glucose < 45 mg/dl if symptomatic will be treated as hypoglycemia 07/03/13 147S O MAIYEGUN MD
  • 148.  Glucose level less than 30mg/dL (<30mg/dL) by I-STAT will be admitted to EPCH  Treatment will not be postponed  Newborns will be formula fed as medically indicated for hypoglycemia less than 30mg/dl prior to admission to EPCH at 10ml/kg 07/03/13 148S O MAIYEGUN MD
  • 149.  Pre-prandial serum glucose q 3 hours during the first 24 hours of life  Glucometer and confirmed by I-STAT if level is less than 40mg/dl 07/03/13 149S O MAIYEGUN MD
  • 150.  Glucose Series =>  Glucose level > 30mg/dL but < 40 mg/dL immediate feeding and a repeat glucose 30 to 60 minutes after feeding  If repeat glucose is > 40mg/dL monitor pre- prandial glucoses and oral feedings every 3 hours for 24 hours 07/03/13 150S O MAIYEGUN MD
  • 151.  Glucose is < 40mg/dL after initial feeding, and result after one hour postprandial retesting is still < 40mg/dL transfer to EPCH  Glucose level > 40mg/dL will be treated orally by breastfeeding every 1 to 3 hours expressed formula and/or house formula every 2-3 hours 07/03/13 151S O MAIYEGUN MD
  • 152.  Breastfeeding shall occur every 1 to 3 hours and on demand  If at 24 hours preprandial glucoses are < 50 mg/dL, preprandial glucose should be monitored another 12 hours  If preprandial glucoses are < 50 mg/dL at 36 hours, the Newborn will be transferred to EPCH for further evaluation 07/03/13 152S O MAIYEGUN MD
  • 153.  Problem— ◦ Infant with enlarged scrotum  Plan— ◦ PE to palpate testes ◦ Transilluminate, if unable to palpate testes ◦ If scrotum is hard , indurated & discolored Doppler U/S of testes ◦ Doppler U/S Testicular torsion surgery consult immediately 07/03/13 153S O MAIYEGUN MD
  • 154. 07/03/13 154S O MAIYEGUN MD
  • 155. 07/03/13 155S O MAIYEGUN MD
  • 156.  Problem— ◦ Evidence of hydronephrosis on prenatal ultrasound ◦ Enlarged palpable kidneys on PE ◦ Hydronephrosis on US done for other anomalies 07/03/13 156S O MAIYEGUN MD
  • 157. 07/03/13 157S O MAIYEGUN MD
  • 158. 158  Plan— ◦ Check voiding—if no void in 24 hrs  transfer to IMCN ◦ Minimal hydronephrosis grade 1 US and reassurance if still minimal or negative ◦ If no urine >24hrs UA , BMP and follow protocol for anuria >24hrs 07/03/13 158S O MAIYEGUN MD
  • 159. ◦ Moderate hydronephrosis grade 2  US, if still moderate VCUG, If no urine >24hrs UA , BMP ◦ If VCUG is abnormal discuss with attending for Mx, prophylactic abx ◦ Urology referral as out-pt or in-pt as appropriately 07/03/13 159S O MAIYEGUN MD
  • 160. 160  Plan— ◦ Grade 3 and 4 IMCN ( US, UA , BMP ,VCUG) discuss with attending & mother ◦ Urology referral as in-pt or out-pt as appropriate ◦ Outpatient: FU U/S in 6 weeks (mild and moderate) and if still abnormal VCUG Urology referral as outpt (MAG3) 07/03/13 160S O MAIYEGUN MD
  • 161.  Problem – ◦ Rectal temp > 101.0  Plan – ◦ Unwrap pt & repeat temp in 30 mins ◦ Review maternal hx ( GBS , PROM , fever , s/s of chorio )  If positive  CBC stat or CBC & CRP if > 24 hrs ◦ If temp not decreased in 2 hrs – inform atttending for transfer to IMCN 07/03/13 161S O MAIYEGUN MD
  • 162.  Plan – ◦ Transfer to IMCN if symptomatic @ any time , temp > 102 , abnormal CBC or CRP > 20 or rising ◦ IT ratio >0.2 ◦ No d/c before 48 hrs of age 07/03/13 162S O MAIYEGUN MD
  • 163.  Problem— ◦ Infant with increased muscle tone  Plan— ◦ Perinatal hx for asphyxia , traumatic delivery , dysmorphic features ◦ Suspect drug withdrawal-  Maternal hx  Urine/Mec tox screen in baby  Watch for other signs of withdrawal 07/03/13 163S O MAIYEGUN MD
  • 164.  Plan— ◦ CT scan of head ( structural abnormalities, hemorrhage ) ◦ If dysmorphic features karyotyping ◦ No D/C prior to 48 hrs of age 07/03/13 164S O MAIYEGUN MD
  • 165.  Problem— ◦ Infant with rectal temp < 97.6  Plan – ◦ Evaluate environmental conditions ◦ Check gest age , weight , feedings ◦ Check maternal hx for possibility of ascending infections ◦ Place under radiant warmer & check rectal temp in 30 mins 07/03/13 165S O MAIYEGUN MD
  • 166.  Plan— ◦ If persistent low temps > 2hrs – CBC , CRP ◦ If results abnormal  transfer to IMCN ◦ If 2 temp drops  CBC stat or CBC& CRP if > 24hrs If results abnormal ,transfer to IMCN ◦ If 3 temp drops  transfer to IMCN 07/03/13 166S O MAIYEGUN MD
  • 167.  Problem— ◦ Floppy infant  Plan— ◦ Complete CNS exam ◦ Maternal narcotic admn in last 4hrs PTD  I/M Narcan ( 0.1 mg/kg ) ◦ Maternal h/o of MgSO4 tx for PIH  If present – magnesium level 07/03/13 167S O MAIYEGUN MD
  • 168.  Plan— ◦ Birth h/o asphyxia ; apgar scores ◦ Check feeding ◦ Lab w/u—  Mg , glucose , HCT , CBC ,CRP  Head US (consult attending ) ◦ Discuss with mother ◦ No d/c home prior to 48 hrs of age 07/03/13 168S O MAIYEGUN MD
  • 170.  Problem— ◦ Maternal h/o diabetes  Plan— ◦ PE for associated anomalies ◦ If no stool – discuss with attending ◦ Place on glucose monitoring series  If 2 drops in glucose ( <40 mg %) while on the series , transfer to IMCN  If glucose is < 30 mg% at any time transfer 07/03/13 170S O MAIYEGUN MD
  • 171. 07/03/13 171S O MAIYEGUN MD
  • 172.  Plan— ◦ Check HCT  If > 65 ( central ) and symptomatic transfer to SCN ◦ If jittery , check Se calcium & glucose at once ◦ Discuss with mother ◦ No d/c prior to 48 hrs of age 07/03/13 172S O MAIYEGUN MD
  • 173.  Problem— ◦ Maternal h/o substance abuse during pregnancy ◦ Maternal h/o substance abuse ◦ Maternal s/s suggestive of drug or alcohol use ◦ Positive toxicology in mother ◦ Unexplained irritability /jitteriness in baby 07/03/13 173S O MAIYEGUN MD
  • 174. 07/03/13 174S O MAIYEGUN MD
  • 175.  Plan— ◦ Observe infant for s/s of withdrawal ◦ Check mother’s urine tox ◦ Send meconium and urine tox screen in baby ◦ If h/o cocaine use during pregnancy and urine tox is positive in baby transfer to IMCN 07/03/13 175S O MAIYEGUN MD
  • 176. ◦ If h/o marijuana use & urine tox is negative in baby, observe in MB for 48hrs ◦ If h/o amphetamine use during pregnancy or urine tox is positive in baby IMCN ◦ If negative amphetamine in baby’s urine tox screen observe in MB for 48hrs 07/03/13 176S O MAIYEGUN MD
  • 177.  Plan – ◦ If baby’s & mother’s tox screen is negative – observe in MB ◦ Check maternal HBsAg & HIV status ◦ ***Social service consult ◦ If any signs of withdrawal ,discuss with attending or transfer to IMCN ◦ No d/c prior to 48 hrs of age 07/03/13 177S O MAIYEGUN MD
  • 179. ◦ All O+ and RH- mothers baby's blood group and Coombs ◦ J-meter q shift (routine) on all babies 07/03/13 179S O MAIYEGUN MD
  • 180.  Appears within 24 hours  Level rises > 0.5mg/dl/hour  Evidence of hemolysis(↑ bili,↑retics, ↓hct)  Physical exam is abnormal  Direct bilirubin > 20% of total bilirubin (Tbili) 07/03/13S O MAIYEGUN MD 180
  • 181. ◦ Causes: ◦ Excessive bruising ◦ Cephalhematoma ◦ Subdural hematoma ◦ IDM, breastfeeding ◦ Galatosemia ◦ G6PD deficiency ◦ Polycythemia ◦ Hemoglobinopathy, etc 07/03/13 181S O MAIYEGUN MD
  • 182.  Plan—  J-meter q shift  Rh & ABO incompatibility J meter q 6 hrs or 12 hrs and T.bili and retics count earlier (6hr) or at 24hrs (depending on severity)  If retics is high and bili increasing Hct earlier (6hr) or at 24hrs ( depending on severity) 07/03/13 182S O MAIYEGUN MD
  • 183. ***If any child is jaundiced in the 1st 24 hrs of life and J-meter is above the curve  Do initial total bilirubin ,if above the curve as per the risks in the child  plan for phototherapy (PT)  If below the curve as per the risks then FU J- meter q shift and fractionated bili q 12 hrs as necessary 07/03/13 183S O MAIYEGUN MD
  • 184.  If concerning do F.Bili q 4-6 hrs and decide  If the rate of rise is greater than 0.5mg/dl/hr or above the appropriate curve plan for PT  If set-up for sepsis discuss transfer to IMCN 07/03/13 184S O MAIYEGUN MD
  • 185.  Obtain informed consent from mother prior to PT  Start PT as per jaundice chart  Use total bilirubin (do not subtract direct bilirubin)  Keep baby naked (genitalia and eyes covered)  Monitor temperature and thermal environment  Monitor input/output and increase fluid intake by 10ml/kg/PT 07/03/13MAIYEGUN MD 185
  • 186.  Provide irradiance of at least 4µW/cm2/nm  Provide irradiance 30 4µW/cm2/nm or > if intensive PT is needed  Use double or triple light with biliblanket if level is high or rapidly rising  Brief interruption for feeding will not interfere with PT 07/03/13MAIYEGUN MD 186
  • 187.  Lab w/u in infant’s under phototx— ◦ CBC at 24hr of life ; retics count (ABO or Rh) ◦ Follow F. bili q 6-12 hrs ◦ If bili rising then order hct and retics ◦ BMP ± Urine SG (dehydration) ◦ Urine reducing substance ( if Coombs neg) r/o galactosemia 07/03/13 187S O MAIYEGUN MD
  • 188. ◦ Peripheral smear ( if Coombs neg and severe), spherocytosis (Fx Hx) ,fragmented RBCs in hemolysis ◦ If African/Asian/ Middle Eastern and severe and Coombs neg  G6PD assay ◦ If there is setup for sepsis or abnormal labs discuss for transfer to IMCN 07/03/13 188S O MAIYEGUN MD
  • 189. ◦ Discontinue phototx  when bili decreases 2 consecutive times  check bili at 12 hrs after stopping phototx (d/c home if rebound does not exceed 3.0 mg/dl)  Direct bilirubin > 20% of total bilirubin (Tbili) 07/03/13S O MAIYEGUN MD 189
  • 190. ◦ If direct bili rising, please inform attending  Direct hyperbili >20% of the total bilirubin is abnormal at any age ◦ Urine reducing substance (galactosemia) ◦ UA for bilirubin ◦ No PT or discontinue ◦ Physical exam (hepato-splenomegaly) ◦ Discuss for transfer to IMCN for further work- up 07/03/13 190S O MAIYEGUN MD
  • 191. 07/03/13 191S O MAIYEGUN MD
  • 192. 07/03/13 192S O MAIYEGUN MD
  • 193.  Jitteriness is not associated with ocular deviation  Generalized and symmetrical  It is stimulus sensitive (easily stopped with passive movement of the limb by holding onto the baby’sarm)  Also becoming most prominent after startle  The movement resembles a tremor, and no autonomic changes are associated with it 07/03/13 193S O MAIYEGUN MD
  • 194.  Plan— ◦ Maternal h/o drug use, diabetes,infections ◦ Check initial CBC stat or CBC & CRP at 24hrs, if set-up for sepsis ◦ Urine and mec toxicology screen ◦ Ionized Ca , glucose level ◦ If severe, check Mg ,Phosphate, Parathyroid hormone (PTH) 07/03/13 194S O MAIYEGUN MD
  • 195.  Plan— ◦ Discuss with attending if CBC ,CRP abnormal ◦ Hypocalcemia: If Se Ca is < 2.0mmol/L (8.0mg/dl) and ionized calcium < 1.0mmol/L (4.0mg/dl) in symptomatic NB discuss ◦ Se calcium < 7.0 mg /dl and ionized calcium < 0.9mmol/L (3.6mg/dl) asymptomatic discuss 07/03/13 195S O MAIYEGUN MD
  • 196. ◦ If Se Magnesium < 1.0 mg/dl with hypocalcaemia –discuss for transfer ◦ If Se Glucose < 40 mg/dl --- follow glucose protocol ◦ FU results for discussion 07/03/13 196S O MAIYEGUN MD
  • 198.  Problem— ◦ BW > 3800gms ◦ Wt > 90 %ile for gestational age  Plan— ◦ Place on glucose series & follow protocol ◦ Check HCT ◦ Maternal h/o diabetes ◦ PE for brachial plexus injuries & clavicular fractures 07/03/13 198S O MAIYEGUN MD
  • 200.  Problem— ◦ Head circumference > 38.0 cm ◦ HC disproportionately greater than 50th % tile to BW & length  Plan— ◦ Check HC yourself ◦ Family hx of large heads ◦ Maternal h/o TORCH infections ◦ Check head for split sutures 07/03/13 200S O MAIYEGUN MD
  • 201. 07/03/13 201S O MAIYEGUN MD
  • 202.  Plan— ◦ Head US if abnormally split sutures ◦ Transilluminate skull ◦ If transillumination positive or hydrocephalus present, inform attending for discussion ◦ CT head as needed 07/03/13 202S O MAIYEGUN MD
  • 203.  Mom given MgSO4:  If term baby, stable in nursery or MB and asymptomatic: NO serum magnesium necessary, but monitor closely  If symptomatic (preterm, poor feeding, low apgar scores, apnea, resp distress or frequent desaturation, cyanosis, no meconium in >48hours) then  serum magnesium ± transfer to IMCN/ICN as appropriate 07/03/13 203S O MAIYEGUN MD
  • 204.  No meconium in >48hours  99% of term and 76% of preterm pass stool in the 1st 24hrs  99% of preterm pass stool in the 48hrs  Plans :  Medications in mother: MgSO4, opiates  Imperforate anus, intestinal obstruction, hirschsprung disease, malrotation, meconium plug/ileus, duodenal atresia, small left colon syndrome (IDM) 07/03/13 204S O MAIYEGUN MD
  • 205.  PE: Document patency of the anus (rectal thermometer or feeding tube  Abdominal exam ( distension, rigidity, BS, mass)  CBC stat or CBC& CRP if set up for sepsis  KUB stat  If Hx of drug use urine and mec tox screen  S. magnesium level if maternal MgSO4  FT4 and TSH 07/03/13 205S O MAIYEGUN MD
  • 206.  If all labs normal, If no meconium > 48 hours consider barium enema to evaluate for Hirschsprung disease  Surgical consultation for rectal biopsy  ***Discuss the use of suppository after 48hours with attending  No discharge until passage of stool 07/03/13S O MAIYEGUN MD 206
  • 207.  Problem— ◦ Infant with small head ( HC <10%ile) or greater than 50th percentile difference between head & weight /length  Plan— ◦ Maternal hx for TORCH infections , drug or alcohol use ,Rxn drugs ( phenytoin) ◦ Fam hx of small heads & MR 07/03/13 207S O MAIYEGUN MD
  • 208.  Plan— ◦ Head US /CT scan ◦ If needed Total IgM for TORCHES & Urine culture for CMV ◦ Discuss with faculty 07/03/13 208S O MAIYEGUN MD
  • 209.  Perinatal Hx  Exam for resp distress  Pulse ox stat and continuous as needed  CXR to r/o abnormalities  CBC stat or CBC& CRP(>24hrs) if set up for sepsis  If significant abnormal results consider transfer to EPCH  If grunting (discuss and consider transfer) 07/03/13S O MAIYEGUN MD 209
  • 210. 07/03/13 210S O MAIYEGUN MD
  • 211. Apparently healthy infant noted to have heart murmur on PE  Grade 1-2 murmur @ birth  Acyanotic with no significant problems ,re- examine @ 2nd day of life  Grade 3-4 on day 1 or significant murmur found on 2nd day of life 07/03/13 211S O MAIYEGUN MD
  • 212.  Plan— ◦ Full cardiac exam  4 limb BP’s  Pulse ox- spot or continuous as appropriate  Hepatosplenomegaly  Feeding  CXR (cardiac shape)  Echocardiogram (specific and diagnostic) ◦ EKG as needed 07/03/13 212S O MAIYEGUN MD
  • 213.  Plan— ◦ Cyanosis or severe respiratory distress  transfer to IMCN ◦ Grade 1-2 murmur on 1st day of life with symptoms ◦ Discuss with faculty for possible transfer to IMCN/ICN 07/03/13 213S O MAIYEGUN MD
  • 214. P 07/03/13 214S O MAIYEGUN MD
  • 215.  Problem— ◦ Red/purple , non-blanching spots on skin/ face  Plan— ◦ Maternal hx of TORCH infection or at risk for ascending infection ◦ Maternal labs –thrombocytopenia ◦ CBC stat and CBC and CRP at 24hrs ◦ Perinatal h/o asphyxia , nuchal cord , trauma , forceps ◦ Observe for signs of sepsis & discuss with attending 07/03/13 215S O MAIYEGUN MD
  • 216.  All high risk babies are screen with capillary hematocrit  Central venous hematocrit >65%  If capillary hematocrit is more than 65% repeat from central venous from a cubital vein ◦ Central HCT ( no tourniquet , deep vein , no femoral sticks ) ◦ Check for jaundice ; check Se glucose 07/03/13 216S O MAIYEGUN MD
  • 217.  Symptoms of hyperviscosity: Plethora  temperature instability  feeding problems  plethora  irritability  lethargy  hypoglycemia  respiratory distress  hypoperfusion 07/03/13 217S O MAIYEGUN MD
  • 218.  Central Hct is 65-69% and the infant is asymptomatic no intervention is warranted, repeat central Hct at 24 hrs  If ≥ 65 % and the infant is symptomatic IMCN for partial exchange reduction  If >70% IMCN for a partial reduction exchange  Discuss with faculty 07/03/13 218S O MAIYEGUN MD
  • 219.
  • 220.  Ulnar or postaxial polydactyly commonly isolated in African black children, autosomal dominant transmission  More frequent in blacks than in whites and is more frequent in male children 07/03/13 220S O MAIYEGUN MD
  • 221.  Ulnar or postaxial polydactyly commonly isolated in African black children, autosomal dominant transmission  More frequent in blacks than in whites and is more frequent in male children 07/03/13 221S O MAIYEGUN MD
  • 222.  In contrast, postaxial polydactyly seen in white children is usually syndromic and associated with an autosomal recessive transmission  Radial or preaxial polydactyly is frequently associated with several syndromes  Any other forms of polydactyly/syndacytly/cleft hand or feet need orthopedic consult 07/03/13 222S O MAIYEGUN MD
  • 223.  Problem— ◦ Skin tag or extra digit on healthy infant ◦ Look for other dysmorphic features ◦ Document pre or post-axial polydactyl  Plan— ◦ Inform mother ◦ If skin tag has a thin pedicle tie off with vicryl suture after obtaining informed consent from mother 07/03/13 223S O MAIYEGUN MD
  • 224. ◦ Extra digit—  X-rays to document if bone present ◦ If no bone  can tie off with vicryl suture after obtaining informed consent from mother  If bone present refer to pediatrics orthopedics as outpatient  Any lower limb polydactyl or preaxial need referral to orthopedics 07/03/13 224S O MAIYEGUN MD
  • 226.  Persistent respiratory distress beyond 4 hrs transitional period  Retractions (I/C and S/C), moaning, grunting  Respiratory rate: persistently >60/min  Frequent desaturations  Cyanotic episodes  Plans: CXR stat (to r/o pneumonia, pneumothorax, cardiac shape )  CBC and if >24hrs CBC & CRP  Discuss with faculty for transfer to IMCN 07/03/13 226S O MAIYEGUN MD
  • 227. 07/03/13 227S O MAIYEGUN MD
  • 228.  Problem – ◦ Mother with positive serology for syphilis ◦ RPR and TPPA  Plan— ◦ RPR on baby ◦ Detailed maternal hx ( confirmatory labs & treatment hx) ◦ If mothers TPPA negative no issues 07/03/13 228S O MAIYEGUN MD
  • 229.  Plan— ◦ If mothers TPPA is positive  ◦ detailed h/o treatment  documented evidence of drug used (Penicillin)  timing of tx  decreased titers 4x after tx  evidence of tx of spouse ) 07/03/13 229S O MAIYEGUN MD
  • 230. ◦ Transfer to IMCN for full work-up ◦ If baby’s titer is at least 4 X maternal titer ◦ No h/o tx  Last dose of PCN within the last month prior to delivery  Drug other than PCN used  No evidence of decreased titers  Possibility of re-infection( no tx of spouse) 07/03/13 230S O MAIYEGUN MD
  • 231.  Plan  If mothers TPPA + & documentation of satisfactory treatment available (follow the CDC guideline attached)  refer to ID as out-pt after discussion with faculty ◦ Transfer to IMCN if infants RPR > 1:4 after discussion with faculty 07/03/13 231S O MAIYEGUN MD
  • 232. S 07/03/13 232S O MAIYEGUN MD
  • 233.  Problem— ◦ Maternal h/o SLE  Plan— ◦ EKG ( bradycardia , complete ht block) ◦ CBC (thrombocytopenia/leukopenia/anemia) ◦ Examine skin for rash ,if present – no sun exposure, self limiting ◦ FU with PCP 07/03/13 233S O MAIYEGUN MD
  • 234.  Problem— ◦ Weight < 10%ile for age  Plan— ◦ Determine gestational age ◦ Determine IUGR status ◦ Maternal h/o placental insufficiency , TORCH infections , nutrition hx ,h/o chronic diseases & drug use ) 07/03/13 234S O MAIYEGUN MD
  • 235.  Plan  Place on glucose series ◦ Check HCT ◦ Follow feedings ◦ Follow temperatures ◦ If hx suggestive of TORCH infection –CBC , Total IgM & discuss with attending 07/03/13 235S O MAIYEGUN MD
  • 236.  Problem— ◦ Stuffy nose , trouble breathing  Plan— ◦ Check patency of nares ( pass 8Fr feeding tube B/L ) auscultate for air passing through each nare after blocking the other one) ◦ Pulse ox as needed ◦ Normal saline nasal drops and bulb suction ◦ Bedside Humidifier (cool mist) 07/03/13 236S O MAIYEGUN MD
  • 237.  Plan—  Check maternal h/o syphilis ( snuffles) ◦ Follow feedings ◦ If severe discuss with attending ◦ Bedside Humidifier (cool mist) @ home 07/03/13 237S O MAIYEGUN MD
  • 238.  Bleeding in the potential space between the periosteum and the galea aponeurosis  Risk factors as in cephalhematoma  Fluctuant boggy mass and crosses the suture lines  Hemorrhagic shock and significant hyperbilirubinemia  Labs for coagulopathy  Close observation, if severe  IMCN 07/03/13 238S O MAIYEGUN MD
  • 240.  HR persistently more than 160-175bpm or > 2SD above the mean for age, asleep or awake  Plan:  Maternal Hx of thyroid disorder  Fever  check temperature  Birth Hx (forceps or vaccum)  EKG stat  CXR and CBC stat and >24hrs CBC and CRP  Inform attending for transfer to IMCN 07/03/13 240S O MAIYEGUN MD
  • 241.  Problem— ◦ Infant born with teeth ( loose or firm) ;either visible or soft mucoid tissue cysts along alveolar ridge with palpable loose tooth in it  Plan— ◦ If loose  talk with mother regarding need for removal refer to dentist ◦ If well embedded  can FU later with dentist 07/03/13 241S O MAIYEGUN MD
  • 242. 07/03/13 242S O MAIYEGUN MD
  • 243.  Problem— ◦ Empty scrotum or hemiscrotum  Plan— ◦ Unilateral cryptorchidism – no intervention  Urology consult as out-pt ◦ Bilateral, with no palpable testes in canal abdominal US (testes, ovaries, adrenals) ◦ If U/S shows abdominal testes  Urology consult as out-pt 07/03/13 243S O MAIYEGUN MD
  • 244. ◦ Bilateral with palpable testes in inguinal canal no intervention recheck gestational age ◦ If no testes on US ambiguous genitalia protocol 07/03/13 244S O MAIYEGUN MD
  • 245.  Problem— ◦ Maternal h/o thrombocytopenia at time of delivery or during pregnancy ◦ Platelet count< 150,000  Plan: Repeat platelet count before decision is made  CBC with platelet on baby ◦ If < 50,000 – transfer to IMCN ◦ If > 50,000 – repeat in 24 hrs ◦ Check baby for petechiae ,bruising, oozing from cord 07/03/13 245S O MAIYEGUN MD
  • 247.  4% of newborns  Can breastfeed without difficulty, but in some cases, a tight frenulum makes latching on difficult  No evidence based reason to clip the frenulum in the nursery  In cases of difficulty feeding , frenotomy may be indicated 07/03/13S O MAIYEGUN MD 247
  • 248.  Problem— ◦ Single umbilical artery  Plan— ◦ Renal US ◦ Check for urination ◦ Check for dysmorphic features 07/03/13 248S O MAIYEGUN MD
  • 250. U 07/03/13 250S O MAIYEGUN MD
  • 251.  Urate crystals look different from blood in the newborn’s diaper but can be confused  They tend to sit on the surface of the diaper and are iridescent and completely benign  M=F  More observed in boys 07/03/13S O MAIYEGUN MD 251
  • 252.  No urine in > 24hrs  100% of neonates pass urine in 24 hours Plan:  Maternal History: olighydramnios (renal anomalies)  Prenatal history of fetal hydronephrosis, kidney anomalies  Check L& D papers  MOST likely reason: undocumented void in the delivery room 07/03/13 252S O MAIYEGUN MD
  • 253.  Make sure there is adequate intake, lactation consult if necessary  Supplement with formula if needed 07/03/13 253S O MAIYEGUN MD
  • 254.  If no urine more than 24hrs   Placed a cotton ball between the labia or a urine bag ( check urine)  Bladder palpable (manual compression may initiate voiding) if a boy think of PUV  Bladder catheterization If no urine US bladder, kidneys IMCN for further workup  Check BP, BMP  No discharge until the passage of stool and urine can be documented 07/03/13S O MAIYEGUN MD 254
  • 255.  There is no immediate danger to the baby, so parents can sign that they do not consent  There is no need for social service consult 07/03/13S O MAIYEGUN MD 255
  • 256.  Projectile and forceful, vomiting with feedings >2, ± abdominal distension/tenderness  Greenish emesis or Bloody emesis  Confirm passage of meconium  Look for dysmorphic features (Down Syndrome) 07/03/13 256S O MAIYEGUN MD
  • 257.  Plan: Hx of sepsis set-up  KUB stat (NEC, pneumoperitoneum, double bubble, etc )  CBC stat or CBC & CRP >24hrs  Inform faculty 07/03/13 257S O MAIYEGUN MD
  • 259.  Most common  Dermal melanocytosis  96% of African-American  46% of Hispanic  10% of white children  Common locations are the buttocks, midsacral but shoulders and extremities may be involved 07/03/13 259S O MAIYEGUN MD
  • 260. 07/03/13 260S O MAIYEGUN MD Reassurance
  • 262. 07/03/13 262S O MAIYEGUN MD Reassurane
  • 263.  Sebaceous retention cyst  These small, whitish-yellow papules are found close to the skin surface, being particularly common around the eyes and midface  Reassurance 07/03/13 263S O MAIYEGUN MD
  • 264.  Note the yellowish papules on the nose of this infant  Sebaceous gland hyperplasia  Reassurance 07/03/13 264S O MAIYEGUN MD
  • 265.  Caused by sweat retention  Characterized by a vesicular eruption with subsequent maceration and obstruction of the eccrine ducts  Keratinous plugging of eccrine ducts and the escape of eccrine sweat into the skin below the level of obstruction
  • 266.  Miliaria crystallina (sudamina): clear superficial pinpoint vesicles without an inflammatory areola  Miliaria rubra (prickly heat): deeper level of sweat gland obstruction, and characterized by small discrete erythematous papules, vesicles, or papulovesicles
  • 267.  Sweat rash and heat rash :ducts connecting sweat glands with the surface of the skin get blocked & perspiration gets trapped under the skin  Reassurance 07/03/13S O MAIYEGUN MD 267
  • 269.  Numerous tiny erythematous papular lesions on face, neck, and upper trunk  Reassurance
  • 270.  Numerous tiny papulo-pustular lesions  Cytologic exam :inflammatory cells  Gram staining may reveal gram+cocci (staphylococci)  Sepsis workup and antibiotics as needed
  • 271. 07/03/13 271S O MAIYEGUN MD Reassurance
  • 272. 07/03/13 272S O MAIYEGUN MD
  • 273.  Pearls (sebaceous retention cyst) may be found in a variety of locations in the newborn  The tip of the foreskin is another relatively common location  The pearl is a small, firm, white nodule that contains keratin  It will spontaneously exfoliate and resolve with time  It is a normal finding and is not a contraindication to circumcision, if desired 07/03/13 273S O MAIYEGUN MD
  • 274.  Numerous yellow papules and pustules are surrounded by large intensely erythematous rings  50% of full terms  Rare in preterms  Eosinophils + (Wright stain)  Reassurance 07/03/13 274S O MAIYEGUN MD
  • 275.  Note the reticulated bluish- purple mottling of this infant's thigh  -Vasomotor instability  -Normal  -Poor perfusion, hypovolumia  -septic shock  -Cornelia de Lange syndrome  -Down syndrome 07/03/13 275S O MAIYEGUN MD
  • 276.  Nevus flammeus neonatorum: a typical light red splotchy area is seen at the nape of the neck and forehead  Dilated superficial capillaries  Reassurance 07/03/13 276S O MAIYEGUN MD
  • 277.  Characteristic purplish-red lesion covering nearly half of face  Capillary malformation  If neurologic signs MRI brain and Ophthalmology consult  Reassurance 07/03/13 277S O MAIYEGUN MD
  • 278.  Multiple soft, red, raised lesions dot the back and arms  Reassurance 07/03/13 278S O MAIYEGUN MD
  • 279.  The vessels that make up this large, partially compressible lesion are deep beneath the skin surface but still impart a bluish hue to the overlying skin. Note the indistinctness of the margins.  MRI chest
  • 280.  The hemangioma on this child's nasal bridge has both superficial and deep components.  MRI brain
  • 281.  A, Two small nevi with differing degrees of hyperpigmentation  B, The giant nevus covering the lower back and buttocks, is uniformly pigmented and has smaller satellite nevi.  MRI spine
  • 282.  Red papules and pustules are present over the nose and cheeks 07/03/13 282S O MAIYEGUN MD
  • 283.  Present at birth  Pustules without surrounding erythema  Ruptured pustules with hyperpigmented macules with a rim of surrounding scale  Occur in 5% African- American, rare in other racial groups  Pustules contain PMN’s 07/03/13 283S O MAIYEGUN MD
  • 284. 07/03/13 284S O MAIYEGUN MD
  • 285. 07/03/13 285S O MAIYEGUN MD
  • 286. 07/03/13 286S O MAIYEGUN MD
  • 287.  While the blister created by the infant sucking on his extremity in the womb may still be intact at the time of delivery  Often it appears as a flat, scabbed, healing area (as shown)  Sucking blisters are solitary lesions that occur only in areas accessible to the infant's mouth  They are benign and resolve spontaneously  The appearance and location of the lesion is usually sufficient for diagnosis, but if the infant is observed sucking on the affected area, the diagnosis is certain 07/03/13 287S O MAIYEGUN MD
  • 288. Breakage of small vessels during the pressure of delivery Reassurance
  • 294. Reassurance and FU with plastic surgery/ dermatologist if severe
  • 295. Reassurance and FU with plastic surgery/ dermatologist if severe
  • 296. Reassurance and FU with plastic surgery/ dermatologist if severe
  • 297.  Normal  Scalp electrode placement  Vascular compromise  Methimazole  Trisomy 13 07/03/13S O MAIYEGUN MD 297
  • 300. NEONATAL SLE Screen for SLE abx, Congenital heart block or thrombocytopenia
  • 302. NEONATAL SLE Screen for SLE abx, Congenital heart block or thrombocytopenia
  • 303. Rubella, dermal extramedullary hematopoiesis, infiltrative neoplastic lesions of the skin, and cutaneous vascular anomalies NICU transfer for workup
  • 304.
  • 307.  http://newborns.stanford.edu/PhotoGallery  Atlas of Pediatric Physical Diagnosis : Basil J. Zitelli MD, Holly W. Davis MD  Nelson Textbook of Pediatrics  The Atlas of Emergency Medicine .Chapter 15. Child Abuse  Lynne Uhring, MD, FAAP  Frequently Asked Questions About Newborn Babies 07/03/13 307S O MAIYEGUN MD
  • 308.  Carrie L. Byington and Carol J. Baker: CDC updates guidelines on prevention of perinatal GBS ,AAP News, Dec 2012  Revised previous edition by Dr. N Singh  Guidelines for Perinatal Care, 7th Edition Jointly developed by the AAP Committee on Fetus and Newborn and ACOG Committee on Obstetric Practice 07/03/13S O MAIYEGUN MD 308
  • 309.  Red Book: 2012 Report of the Committee on Infectious Diseases, 29th Edition  Lynne Uhring, MD, FAAP  Frequently Asked Questions About Newborn Babies  Neonatology Management, procedure, on-call problems, diseases and drugs: 6th Edition, Gomella TL 07/03/13S O MAIYEGUN MD 309

Editor's Notes

  1. 07/03/13 SOMAIYEGUN MD
  2. SOMAIYEGUN MD 07/03/13
  3. 07/03/13 SOMAIYEGUN MD
  4. 07/03/13 SOMAIYEGUN MD
  5. 07/03/13 SOMAIYEGUN MD
  6. 07/03/13 SOMAIYEGUN MD
  7. 07/03/13 SOMAIYEGUN MD
  8. 07/03/13 SOMAIYEGUN MD
  9. 07/03/13 SOMAIYEGUN MD
  10. 07/03/13 SOMAIYEGUN MD
  11. 07/03/13 SOMAIYEGUN MD
  12. 07/03/13 SOMAIYEGUN MD
  13. 07/03/13 SOMAIYEGUN MD
  14. 7/6/2010 SOMAIYEGUN MD SOMAIYEGUN MD
  15. 07/03/13 SOMAIYEGUN MD
  16. 07/03/13 SOMAIYEGUN MD
  17. 7/6/2010 SOMAIYEGUN MD SOMAIYEGUN MD
  18. 07/03/13 SOMAIYEGUN MD
  19. 07/03/13 SOMAIYEGUN MD
  20. 07/03/13 SOMAIYEGUN MD
  21. 07/03/13 SOMAIYEGUN MD
  22. 07/03/13 SOMAIYEGUN MD
  23. 07/03/13 SOMAIYEGUN MD
  24. 07/03/13 SOMAIYEGUN MD
  25. 07/03/13 SOMAIYEGUN MD
  26. 07/03/13 SOMAIYEGUN MD
  27. 07/03/13 SOMAIYEGUN MD
  28. SOMAIYEGUN MD
  29. SOMAIYEGUN MD
  30. SOMAIYEGUN MD
  31. 7/6/2010 SOMAIYEGUN MD SOMAIYEGUN MD
  32. 07/03/13 SOMAIYEGUN MD
  33. 07/03/13 SOMAIYEGUN MD
  34. 07/03/13 SOMAIYEGUN MD
  35. SOMAIYEGUN MD
  36. 07/03/13 SOMAIYEGUN MD
  37. 07/03/13 SOMAIYEGUN MD
  38. 07/03/13 SOMAIYEGUN MD
  39. 07/03/13 SOMAIYEGUN MD
  40. 07/03/13 SOMAIYEGUN MD
  41. 07/03/13 SOMAIYEGUN MD
  42. 07/03/13 SOMAIYEGUN MD
  43. 07/03/13 SOMAIYEGUN MD
  44. 07/03/13 SOMAIYEGUN MD
  45. 07/03/13 SOMAIYEGUN MD
  46. 07/03/13 SOMAIYEGUN MD
  47. 07/03/13 SOMAIYEGUN MD
  48. 07/03/13 SOMAIYEGUN MD
  49. 07/03/13 SOMAIYEGUN MD
  50. 07/03/13 SOMAIYEGUN MD
  51. 07/03/13 SOMAIYEGUN MD
  52. 07/03/13 SOMAIYEGUN MD
  53. 07/03/13 SOMAIYEGUN MD
  54. 07/03/13 SOMAIYEGUN MD
  55. 07/03/13 SOMAIYEGUN MD
  56. SOMAIYEGUN MD
  57. SOMAIYEGUN MD
  58. SOMAIYEGUN MD
  59. 07/03/13 SOMAIYEGUN MD
  60. 7/6/2010 SOMAIYEGUN MD SOMAIYEGUN MD
  61. 07/03/13 SOMAIYEGUN MD
  62. SOMAIYEGUN MD
  63. SOMAIYEGUN MD
  64. SOMAIYEGUN MD
  65. 07/03/13 SOMAIYEGUN MD
  66. 07/03/13 SOMAIYEGUN MD
  67. 07/03/13 SOMAIYEGUN MD
  68. 07/03/13 SOMAIYEGUN MD
  69. 07/03/13 SOMAIYEGUN MD
  70. 07/03/13 SOMAIYEGUN MD
  71. SOMAIYEGUN MD
  72. SOMAIYEGUN MD
  73. SOMAIYEGUN MD
  74. 07/03/13 SOMAIYEGUN MD
  75. SOMAIYEGUN MD
  76. 07/03/13 SOMAIYEGUN MD
  77. SOMAIYEGUN MD
  78. SOMAIYEGUN MD
  79. SOMAIYEGUN MD
  80. SOMAIYEGUN MD
  81. SOMAIYEGUN MD
  82. SOMAIYEGUN MD
  83. 07/03/13 SOMAIYEGUN MD
  84. 07/03/13 SOMAIYEGUN MD
  85. 07/03/13 SOMAIYEGUN MD
  86. 07/03/13 SOMAIYEGUN MD
  87. 07/03/13 SOMAIYEGUN MD
  88. SOMAIYEGUN MD
  89. 07/03/13 SOMAIYEGUN MD
  90. 07/03/13 SOMAIYEGUN MD
  91. 07/03/13 SOMAIYEGUN MD
  92. 07/03/13 SOMAIYEGUN MD
  93. 07/03/13 SOMAIYEGUN MD
  94. 07/03/13 SOMAIYEGUN MD
  95. 07/03/13 SOMAIYEGUN MD
  96. 07/03/13 SOMAIYEGUN MD
  97. 07/03/13 SOMAIYEGUN MD
  98. 07/03/13 SOMAIYEGUN MD
  99. 07/03/13 SOMAIYEGUN MD
  100. 07/03/13 SOMAIYEGUN MD
  101. 07/03/13 SOMAIYEGUN MD
  102. 07/03/13 SOMAIYEGUN MD
  103. 07/03/13 SOMAIYEGUN MD
  104. 07/03/13 SOMAIYEGUN MD
  105. 07/03/13 SOMAIYEGUN MD
  106. 07/03/13 SOMAIYEGUN MD
  107. 7/6/2010 SOMAIYEGUN MD SOMAIYEGUN MD
  108. SOMAIYEGUN MD
  109. 7/6/2010 SOMAIYEGUN MD SOMAIYEGUN MD
  110. 07/03/13 SOMAIYEGUN MD
  111. 07/03/13 SOMAIYEGUN MD
  112. 07/03/13 SOMAIYEGUN MD
  113. 07/03/13 SOMAIYEGUN MD
  114. 07/03/13 SOMAIYEGUN MD
  115. 07/03/13 SOMAIYEGUN MD
  116. 07/03/13 SOMAIYEGUN MD
  117. 07/03/13 SOMAIYEGUN MD
  118. 07/03/13 SOMAIYEGUN MD
  119. 07/03/13 SOMAIYEGUN MD
  120. 07/03/13 SOMAIYEGUN MD
  121. 07/03/13 SOMAIYEGUN MD
  122. 07/03/13 SOMAIYEGUN MD
  123. 07/03/13 SOMAIYEGUN MD
  124. SOMAIYEGUN MD
  125. 07/03/13 SOMAIYEGUN MD
  126. 07/03/13 SOMAIYEGUN MD
  127. 07/03/13 SOMAIYEGUN MD
  128. SOMAIYEGUN MD
  129. SOMAIYEGUN MD
  130. 07/03/13 SOMAIYEGUN MD
  131. SOMAIYEGUN MD
  132. 07/03/13 SOMAIYEGUN MD
  133. 07/03/13 SOMAIYEGUN MD
  134. 07/03/13 SOMAIYEGUN MD
  135. SOMAIYEGUN MD
  136. 07/03/13 SOMAIYEGUN MD
  137. SOMAIYEGUN MD
  138. 07/03/13 SOMAIYEGUN MD
  139. 07/03/13 SOMAIYEGUN MD
  140. 07/03/13 SOMAIYEGUN MD
  141. 07/03/13 SOMAIYEGUN MD
  142. SOMAIYEGUN MD
  143. SOMAIYEGUN MD
  144. 07/03/13 SOMAIYEGUN MD
  145. 07/03/13 SOMAIYEGUN MD
  146. 07/03/13 SOMAIYEGUN MD
  147. 07/03/13 SOMAIYEGUN MD
  148. 07/03/13 SOMAIYEGUN MD
  149. 07/03/13 SOMAIYEGUN MD
  150. 07/03/13 SOMAIYEGUN MD
  151. 07/03/13 SOMAIYEGUN MD
  152. 07/03/13 SOMAIYEGUN MD
  153. 07/03/13 SOMAIYEGUN MD
  154. 07/03/13 SOMAIYEGUN MD
  155. 07/03/13 SOMAIYEGUN MD
  156. 07/03/13 SOMAIYEGUN MD
  157. 07/03/13 SOMAIYEGUN MD
  158. 07/03/13 SOMAIYEGUN MD
  159. 07/03/13 SOMAIYEGUN MD
  160. SOMAIYEGUN MD
  161. 07/03/13 SOMAIYEGUN MD
  162. 07/03/13 SOMAIYEGUN MD
  163. 07/03/13 SOMAIYEGUN MD
  164. 07/03/13 SOMAIYEGUN MD
  165. 07/03/13 SOMAIYEGUN MD
  166. 07/03/13 SOMAIYEGUN MD
  167. 07/03/13 SOMAIYEGUN MD
  168. 07/03/13 SOMAIYEGUN MD
  169. 07/03/13 SOMAIYEGUN MD
  170. 07/03/13 SOMAIYEGUN MD
  171. 07/03/13 SOMAIYEGUN MD
  172. SOMAIYEGUN MD
  173. 07/03/13 SOMAIYEGUN MD
  174. 07/03/13 SOMAIYEGUN MD
  175. 07/03/13 SOMAIYEGUN MD
  176. SOMAIYEGUN MD
  177. 07/03/13 SOMAIYEGUN MD
  178. 07/03/13 SOMAIYEGUN MD
  179. 7/6/2010 SOMAIYEGUN MD SOMAIYEGUN MD
  180. 07/03/13 SOMAIYEGUN MD
  181. SOMAIYEGUN MD
  182. SOMAIYEGUN MD
  183. SOMAIYEGUN MD
  184. SOMAIYEGUN MD
  185. 07/03/13 SOMAIYEGUN MD
  186. 07/03/13 SOMAIYEGUN MD
  187. Mongolian spots appear on the buttocks, back, and upper arms of many infants.
  188. 07/03/13 SOMAIYEGUN MD
  189. 07/03/13 SOMAIYEGUN MD
  190. 07/03/13 SOMAIYEGUN MD
  191. 07/03/13 SOMAIYEGUN MD
  192. 07/03/13 SOMAIYEGUN MD
  193. 07/03/13 SOMAIYEGUN MD
  194. 07/03/13 SOMAIYEGUN MD
  195. 07/03/13 SOMAIYEGUN MD
  196. 07/03/13 SOMAIYEGUN MD
  197. 07/03/13 SOMAIYEGUN MD
  198. 07/03/13 SOMAIYEGUN MD
  199. SOMAIYEGUN MD 07/03/13
  200. 07/03/13 SOMAIYEGUN MD