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Bioinformatics, comparative genemics and proteomics


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Bioinformatics, comparative genemics and proteomics

  1. 1. Bioinformatics, Comparati ve Genomics, and Proteomics Juan Carlos Torres Sánchez Osvaldo Vega Luz Marie Eduardo Rivera
  2. 2. Bioinformatics• Field of science in which biology, computer science, and information technology merge to form a single discipline.• It use computerized tools, like biological database, to analyze the unique structural and functional features of a genomic DNA sequence.
  3. 3. Bioinformatics• More global perspective in experimental design.• Ability to capitalize on the emerging technology of database-mining.
  4. 4. Comparative Genomics• Comparative Genomics is the study of the relationship of genome structure and function across different biological species or strains.• Comparative Genomics provides a powerful tool for studying evolutionary changes among organisms
  5. 5. Comparative Genomics• Comparative Genomics exploits similarities and differences in the proteins, RNA, and regulatory regions of different organisms to infer how selection has acted upon these elements.• Insights into the genetic diversity of the bacteriophage population and the evolutionary mechanisms that give rise to it can be obtained using comparative genomic analyses.• Comparative Genomics field has brought a lot of great results. a. Cancer b. Parkinson’s disease
  6. 6. Proteomics• The large-scale study of protein structure and function is known as Proteomics.• The word “proteome” is derived from proteins expressed by a genome, and it refers to all the proteins produced by an organism, much like the genome is the entire set of genes.
  7. 7. Proteomics• The Mycobacteriophage proteome consists of the complete set of proteins specified by their genome.• These proteins can also be compared to better understand the similarities and differences between phages.
  8. 8. Conclusion• Bioinformatics, Comparative Genomics and Proteomics have helped gather a lot of knowledge in the area of Mycobacteriophages.• All of these areas of science have helped greatly in the discovery and comparison of previously discovered mycobacteriophages.
  9. 9. Conclusion• Also, they have helped in many other diseases that improve our quality of life.• Bringing new techniques for the patient daily routine checkup.