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Cataract surgery in glaucoma
patients
Presenter:
Dr.Jahidur Rahman
FCPS II Student
NIO&H
Moderator
Dr.Mezbahul Alom
Chairman
Prof. Dr. Iftekhar Md. Munir
INTRODUCTION:
• The coexistence of glaucoma and cataract is a
common occurrence that requires insight into
the diagnosis and management of both
conditions
• The main goal is to enable the optic nerve
to withstand an IOP spike & the
likelihood of maintaining postoperative IOP
control without further surgical intervention
THE IMPACT OF CATARACT ON THE
EVALUATION OF GLAUCOMA
• Worsens the mean deviation across all
tests of the visual field
• Affect the visual field index/ glaucoma
progression index as well as the
characterization of scotomas
• Underestimation of the thickness of the
RNFL
ROLE OF CATARACT SURGERY
ON GLAUCOMA
• produce a significant and sustained IOP
reduction in individuals with open-angle
glaucoma, ocular hypertension, and angle-
closure glaucoma
• Phaco lowers long term IOP by 2-4 mmHg
• improve the practitioner's ability to interpret
perimetric testing & optic nerve imaging
HOW DOES IOP REDUCE?
In patients with CACG:
Removal of the lens would relieve the risk of
pupillary block and posterior forces crowding
the angle
In patients with POAG:
• Reduction of glycosaminoglycan deposition in
the trabecular meshwork due to higher fluid
flow rates
• Inflammation induced morphologic changes in
the trabecular meshwork akin to the effects of
laser trabeculoplasty
• Remodeling of the trabecular endothelium
secondary to ultrasonic vibrations
• Alterations in the blood-aqueous barrier
• Increased posterior zonular traction due to
cataract surgery has been postulated to improve
patency of the trabecular meshwork and result in
lower IOP
SURICAL OPTION:
• The management of coexistent glaucoma and
cataract is a complex issue with several
therapeutic options
• A lack of consensus regarding the best
surgical management still remains
G3 OPTIONS :
• Cataract surgery alone
• Combined cataract and glaucoma surgery
• Or two-phased surgery (glaucoma surgery
followed by cataract surgery, or vice versa)
CHOICE DEPENDS ON -
• The extent of glaucomatous damage
• The type of patient
• The surgeon's individual expertise
• The number of topical medicines the patient
is taking
• The target pressure
• The corneal endothelium, pupillary
& zonular integrity
Challenges
• Small pupils,
• Posterior synechiae,
• Abnormally shallow or deep anterior
chambers, and
• Weakened zonules (especially in patients with
PXF syndrome/glaucoma).
PHACOEMULSIFICATION ALONE
Advantages:
• Quick procedure with rapid visual recovery
• Improved vision which benefits QOL
• Sustained IOP lowering efect
DISADVANTAGES
• IOP lowering effect is less than combined
surgery
• IOP should be watched closely in both the
early postoperative period & later
• Pharmaceutical control of the IOP may be
needed postoperatively
Candidate:
• Mild to moderate glaucoma
• Requiring few medications
Approach:
• 1.Clear corneal:
a.Temporal
b.Superior
• 2.Superior scleral tunnel
Mangement of the pupil
Glaucoma patients have pupil that dilate
poorly due to –
• Sphincter fibrosis from miotic therapy
• Posterior synechia
• Primary condition eg.PXF
• IFIS
Techniques to overcome:
• Pupil stretching by two Kuglen hooks
• Dilatation by Greishaber disposable iris hooks
• Expansion by Malyugin ring
• Intracameral use of 1:1000 epinephrine
Management of the weak zonules:
• Careful thorough hydrodisection &
hydrodelineation
• Avoiding undue pushing of the nucleus with
the tip of the handpiece during sculpting
• A chopping or supra-capsular technique
• Peroperative use of CTR/Cionni ring/Ahmed
capsular tension segment
Completion of surgery
• Acrylic IOL is the best op tion
• A 3-piece acrylic foldable IOL for sulcus fixation
• Diffractive multifocal IOL is avoided as it reduces
contrast sensitivity
• Corneal incisions are checked for any leak
Combined surgery
Indications:
• The presence of cataract and medically
uncontrolled glaucoma
• The early treatment of glaucoma in cataract
patients
• Advanced glaucoma and cataract which is
likely to progress soon after an antiglaucoma
surgical procedure
SURGICAL OPTIONS
Many glaucoma procedures may be combined
with cataract surgery such as-
• Trabeculectomy
• deep sclerectomy, canaloplasty
• Trabectome surgery
• Endoscopic cyclophotocoagulation
• The placement of an Ex-Press mini glaucoma
shunt ,also iStent
ONE/TWO TWO SITE APPROACH
One site approach:
• Phaco by superior scleral incision firstly
• The tunnel is converted to a trabeculectomy
flap& a block of inner tissue is removed
either with a punch or freehand later
• Two site approach:
• Phaco is performed temporally first
• Then routine trabeculctomy superiorly
• It is slightly more successful with regard to
postoperative IOP control than the former
CONJUNCTIVAL FLAP
• Fornix based:
• Allows better visualization during surgery
• Difficult to achieve watertight closure but may
be overcome by –
• a)A continuous vertical mattress suture
described by Wise
• b)Interrupted suture technique in which the
knots are buried into partial thickness corneal
incision
• Limbus based:
• It is closed with a two layer technique:
a)Tenon’s capsule closure followed by
b)Conjunctiva closure
Antimetabolite Used:
a)Mitomycin- C
b)5- fluorouracil
ADVANTAGES
• Minimizes anesthetic risk by combining 2
procedures in 1
• Convenience to patient with 1 trip to operating
room rather than 2
• Cost saving
• May blunt potentially damaging postoperative
IOP spikes in patients with advanced VF loss
• Opportunity to improve vision & IOP at the
same time
DISADVANTAGES
• May not be as effective as long-term IOP
control as trabeculectomy alone
• Increased risk of complications of 2
procedures rather than 1
• Slower visual recovery than cataract alone
CATARACT SURGERY BEFORE TRAB
• Early cataract extraction avoids development of
cataract-a common adverse effect of many
glaucoma procedures
• Within 5 years of trabeculectomy or tube shunt
surgery, half of phakic patients develop a visually
significant cataract.(Jampel HD et al)
• The violation of the conjunctival space by
superior extracapsular cataract extraction in a
prior era made subsequent glaucoma surgery
more difficult
ADVANTAGES
• Phacoemulsification preserves the integrity of
the conjunctiva for future glaucoma procedures.
• Expands the depth of the anterior chamber
• Doesn’t reduce the success of the subsequent
initial trabeculectomy with MMC(Supawavej et
al)
CATARACT Sx AFTER TRAB
• May lead to poor outcomes particularly in
terms of the trabeculectomy failure.Causes -
 Bleb fibrosis by inflammatory mediators
 Reduction in both bleb size and elevation
“Exception to the rule”-1.ACG
2.Shunt surgery
Summary
• In the glaucoma specialist's race against time,
a simple cataract surgery may buy several
years of IOP control and delay the morbidity
of traditional filtering surgeries
• Desired outcome depends on figuring out the
best surgical maneuver on the context of the
presenting disease
Cataract surgery improves glaucoma management in coexisting conditions

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Cataract surgery improves glaucoma management in coexisting conditions

  • 1. Cataract surgery in glaucoma patients Presenter: Dr.Jahidur Rahman FCPS II Student NIO&H Moderator Dr.Mezbahul Alom Chairman Prof. Dr. Iftekhar Md. Munir
  • 2. INTRODUCTION: • The coexistence of glaucoma and cataract is a common occurrence that requires insight into the diagnosis and management of both conditions • The main goal is to enable the optic nerve to withstand an IOP spike & the likelihood of maintaining postoperative IOP control without further surgical intervention
  • 3. THE IMPACT OF CATARACT ON THE EVALUATION OF GLAUCOMA • Worsens the mean deviation across all tests of the visual field • Affect the visual field index/ glaucoma progression index as well as the characterization of scotomas • Underestimation of the thickness of the RNFL
  • 4. ROLE OF CATARACT SURGERY ON GLAUCOMA • produce a significant and sustained IOP reduction in individuals with open-angle glaucoma, ocular hypertension, and angle- closure glaucoma • Phaco lowers long term IOP by 2-4 mmHg • improve the practitioner's ability to interpret perimetric testing & optic nerve imaging
  • 5. HOW DOES IOP REDUCE? In patients with CACG: Removal of the lens would relieve the risk of pupillary block and posterior forces crowding the angle In patients with POAG: • Reduction of glycosaminoglycan deposition in the trabecular meshwork due to higher fluid flow rates
  • 6. • Inflammation induced morphologic changes in the trabecular meshwork akin to the effects of laser trabeculoplasty • Remodeling of the trabecular endothelium secondary to ultrasonic vibrations • Alterations in the blood-aqueous barrier • Increased posterior zonular traction due to cataract surgery has been postulated to improve patency of the trabecular meshwork and result in lower IOP
  • 7. SURICAL OPTION: • The management of coexistent glaucoma and cataract is a complex issue with several therapeutic options • A lack of consensus regarding the best surgical management still remains
  • 8. G3 OPTIONS : • Cataract surgery alone • Combined cataract and glaucoma surgery • Or two-phased surgery (glaucoma surgery followed by cataract surgery, or vice versa)
  • 9. CHOICE DEPENDS ON - • The extent of glaucomatous damage • The type of patient • The surgeon's individual expertise • The number of topical medicines the patient is taking • The target pressure • The corneal endothelium, pupillary & zonular integrity
  • 10. Challenges • Small pupils, • Posterior synechiae, • Abnormally shallow or deep anterior chambers, and • Weakened zonules (especially in patients with PXF syndrome/glaucoma).
  • 11. PHACOEMULSIFICATION ALONE Advantages: • Quick procedure with rapid visual recovery • Improved vision which benefits QOL • Sustained IOP lowering efect
  • 12. DISADVANTAGES • IOP lowering effect is less than combined surgery • IOP should be watched closely in both the early postoperative period & later • Pharmaceutical control of the IOP may be needed postoperatively
  • 13. Candidate: • Mild to moderate glaucoma • Requiring few medications
  • 15. Mangement of the pupil Glaucoma patients have pupil that dilate poorly due to – • Sphincter fibrosis from miotic therapy • Posterior synechia • Primary condition eg.PXF • IFIS
  • 16.
  • 17. Techniques to overcome: • Pupil stretching by two Kuglen hooks • Dilatation by Greishaber disposable iris hooks • Expansion by Malyugin ring • Intracameral use of 1:1000 epinephrine
  • 18. Management of the weak zonules: • Careful thorough hydrodisection & hydrodelineation • Avoiding undue pushing of the nucleus with the tip of the handpiece during sculpting • A chopping or supra-capsular technique • Peroperative use of CTR/Cionni ring/Ahmed capsular tension segment
  • 19. Completion of surgery • Acrylic IOL is the best op tion • A 3-piece acrylic foldable IOL for sulcus fixation • Diffractive multifocal IOL is avoided as it reduces contrast sensitivity • Corneal incisions are checked for any leak
  • 20.
  • 21. Combined surgery Indications: • The presence of cataract and medically uncontrolled glaucoma • The early treatment of glaucoma in cataract patients • Advanced glaucoma and cataract which is likely to progress soon after an antiglaucoma surgical procedure
  • 22. SURGICAL OPTIONS Many glaucoma procedures may be combined with cataract surgery such as- • Trabeculectomy • deep sclerectomy, canaloplasty • Trabectome surgery • Endoscopic cyclophotocoagulation • The placement of an Ex-Press mini glaucoma shunt ,also iStent
  • 23. ONE/TWO TWO SITE APPROACH One site approach: • Phaco by superior scleral incision firstly • The tunnel is converted to a trabeculectomy flap& a block of inner tissue is removed either with a punch or freehand later
  • 24. • Two site approach: • Phaco is performed temporally first • Then routine trabeculctomy superiorly • It is slightly more successful with regard to postoperative IOP control than the former
  • 25. CONJUNCTIVAL FLAP • Fornix based: • Allows better visualization during surgery • Difficult to achieve watertight closure but may be overcome by – • a)A continuous vertical mattress suture described by Wise • b)Interrupted suture technique in which the knots are buried into partial thickness corneal incision
  • 26.
  • 27. • Limbus based: • It is closed with a two layer technique: a)Tenon’s capsule closure followed by b)Conjunctiva closure Antimetabolite Used: a)Mitomycin- C b)5- fluorouracil
  • 28.
  • 29. ADVANTAGES • Minimizes anesthetic risk by combining 2 procedures in 1 • Convenience to patient with 1 trip to operating room rather than 2 • Cost saving • May blunt potentially damaging postoperative IOP spikes in patients with advanced VF loss • Opportunity to improve vision & IOP at the same time
  • 30. DISADVANTAGES • May not be as effective as long-term IOP control as trabeculectomy alone • Increased risk of complications of 2 procedures rather than 1 • Slower visual recovery than cataract alone
  • 31. CATARACT SURGERY BEFORE TRAB • Early cataract extraction avoids development of cataract-a common adverse effect of many glaucoma procedures • Within 5 years of trabeculectomy or tube shunt surgery, half of phakic patients develop a visually significant cataract.(Jampel HD et al) • The violation of the conjunctival space by superior extracapsular cataract extraction in a prior era made subsequent glaucoma surgery more difficult
  • 32. ADVANTAGES • Phacoemulsification preserves the integrity of the conjunctiva for future glaucoma procedures. • Expands the depth of the anterior chamber • Doesn’t reduce the success of the subsequent initial trabeculectomy with MMC(Supawavej et al)
  • 33. CATARACT Sx AFTER TRAB • May lead to poor outcomes particularly in terms of the trabeculectomy failure.Causes -  Bleb fibrosis by inflammatory mediators  Reduction in both bleb size and elevation “Exception to the rule”-1.ACG 2.Shunt surgery
  • 34. Summary • In the glaucoma specialist's race against time, a simple cataract surgery may buy several years of IOP control and delay the morbidity of traditional filtering surgeries • Desired outcome depends on figuring out the best surgical maneuver on the context of the presenting disease