This document discusses benign epithelial tumors of the oral cavity, including papilloma, squamous acanthoma, and keratoacanthoma. It describes the classification, incidence, etiology, clinical features, and histological features of each tumor. Papilloma is a common benign neoplasm originating from the surface epithelium, appearing as finger-like projections. Squamous acanthoma is an uncommon reactive lesion occurring as a flat or elevated white area. Keratoacanthoma resembles an epidermoid carcinoma, appearing as an elevated nodule that develops a crater-like depression over 4-8 weeks.

1. BENIGN TUMORS OF THE
EPITHELIAL TISSUE ORIGIN
INDIAN DENTAL ACADEMY
Leader in continuing Dental Education
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2. OBJECTIVES
At the end of the lecture student should be able to-
-Describe classification, incidence, etiology, clinical features,
histopathological features of papilloma
– Describe classification, incidence, etiology, clinical features,
histopathological features of squamous acanthoma
–Describe classification, incidence, etiology, clinical features,
histopathological features of keratoacanthoma
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3. PAPILLOMA
CLINICAL FEATURES
 Common benign neoplasm originating
from surface epithelium
 Exophytic growth made of finger like
projections
 Roughened, Verrucous or cauliflower
like appearance
Well circumscribed, pedunculated,
 Found on tongue, lips, buccal mucosa,
gingiva & palate
 Few mms in diameter to several cms
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5.  Verruca vulgaris is a tumor of skin
analogo us to oral papillomaPebbly
lesions are seen in multiple hamartomas
& hamartoma and neoplasia syndrome
(cowdens syndrome).
 It is an autosomal dominant disease
characterized by facial trichilemomas
asso. With gastrointestinal tract,
thyroid, CNS & mucocutaneous
abnormalities as well as oral lesions
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6.  Multiple papllilomas
are seen in focal
dermal hypoplasia
syndrome
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7. HISTOLOGIC FEATURES
 Long thin finger like projections
extending above the surface of
mucosa
 Continuous layer of str.sq.
epithelium
 Thin central conn. tissue core
supports nutrients blood vessels
 Proliferation of spinous layer in
pappillary fashion
 Conn. tissue not considered a part
of neoplastic element
 Chr. inflammatory cells persent
 Mitosis sometimes presentwww.indiandetalacademy.com

8.  Treatment
-Excision through the
pedicle
 Mature stratified
squamous epithelium
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9. SQAUMOUS ACANTHOMA
 Uncommon lesion
 Reactive phenomenon of epithelium
 Occurs on any site of the oral mucosa
 Usually in older adults
 small, flat or elevated, white, sessile or pedunculated
lesion on the mucosa
 Epithelial proliferation of markedly thickened layer of
orthokeratin & underlying spinous layer of the cells
 Recur after excision
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10. KERATOACANTHOMA
(self-healing carcinoma,molluscum
psuedocarcinomatum,molluscum sebaceum, verrucoma)
 Resembles epidermoid
carcinoma
Etiology
 genetic & viral factors
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11. Clinical features
 Twice frequently seen in men
 50-70yrs
 8.1% seen on lips
 Lesion appears as elevated & umbilicated or
crateriform with a depressed central core or plug
 Painful/ lympahadenopathy +nt
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12.  Begins as small, firm
nodule
 Develops to full size in 4-
8 weeks
Histological features
 Hyperplastic sq. epith
growing into underlying
conn tissue
 Thickened layer of para
or orthokeratin wit
central plugging
Central keratin plug
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13. •Epithelium occasionally dysplastic
•At the margins normal adjacent epithelium is
elevated towards the central portion of the crater
Treatment
•surgical excision
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14. Summary slide
 Classification
 Incidence
 etiology
 Clinical features
 Histological features
of papilloma, squamous acanthoma, &
keratoacanthoma.
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16. THANK YOU !
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