Melanoma/cosmetic dentistry courses
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The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.for more details please visit www.indiandentalacademy.com
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Melanoma/cosmetic dentistry courses
- 1. OBJECTIVES At the end of the lecture student should be able to understand the – classification, incidence, etiology, clinical features, histopathological features of malignant melanoma www.indiandentalacademy.com
- 2. Neoplasm of epidermal melanocytes May develop in preexisting nevi Skin melanomas common Oral melanomas rare but more aggressive 25% occur in head & neck region 40% on extremities Rest on trunk www.indiandentalacademy.com
- 4. Sun exposure Artificial UV sources – longer wave UVA Freckles… Number of melanocytic nevi. Genetic Factors – Familial History Xeroderma pigmentosum Oral Melanomas arise de novo www.indiandentalacademy.com
- 6. Radial growth phase Initial growth phase Lasts for many years Confined to epidermis Normal shedding of neoplastic cells Penetrating cells destroyed by immune response Vertical growth phase Neoplastic cells populate dermis Increased virulence of neoplastic cells Decreased immune response Metastasis possible www.indiandentalacademy.com
- 7. Superficial spreading melanoma Nodular melanoma- vertical growth phase Lentigo maligna melanoma Acral Lentiginous melanoma www.indiandentalacademy.com
- 8. A- Asymmetry B- Border irregularity C- Color Variegation D- Diameter > 6 mm E - Elevation www.indiandentalacademy.com
- 9. Most common cutaneous melanoma in Caucasians Radial growth phase is known as Premalignant melanosis/ Pagetoid melanoma in situ Tan, Brown, Black or admixed lesion <3cm at diagnosis www.indiandentalacademy.com
- 10. Sun exposed skin, especially back, head & neck, chest, abdomen Radial growth phase lasts for several months to years Vertical growth phase characterized by increase in size, change in color, nodularity, ulceration www.indiandentalacademy.com
- 12. 13% of cutaneous melanoma No or short radial growth phase Sharp delineated nodule with pigmentation May be pink (amelanotic melanoma)/ black Occur on back, head & neck skin of men www.indiandentalacademy.com
- 13. 10% of melanomas Radial growth phase is known as Lentigo maligna or melanotic freckle of Hutchinson Macular lesion on malar skin of middle aged Common in women, not seen in Oral Cavity. www.indiandentalacademy.com
- 16. Most common in Blacks Most common Oral Melanoma Macular, Lentiginous pigmented area around a nodule. Extremely aggressive. Acral lentiginous melanoma Mucosal lentiginous melanoma www.indiandentalacademy.com
- 17. Early lesions – flat, may be nodular 6-7th decade 2/3rd – male Commonly involves - Palate, Maxillary gingival. Other areas - alveolar ridge, buccal mucosa, lips, floor of the mouth Deeply pigmented areas with irregular borders. Ulcerated, hemorrhagic area www.indiandentalacademy.com
- 18. Pain less unless ulcerated Soft to palpation Moth-eaten destruction of bone Oral lesions tend to be aggressive so they have been termed as acral lentiginous melanoma www.indiandentalacademy.com
- 19. Presence of large epitheloid melanocytes Host cell response depending on type of melanoma www.indiandentalacademy.com
- 24. Less Common variants are desmoplastic, neurotropic, spindle cell, balloon cell www.indiandentalacademy.com
- 25. Surgical excision Poor prognosis www.indiandentalacademy.com