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Casework Questions To Ask Your Representatives.
1. Specific questions about vaccines, vaccine safety or the vaccine-autism link.
2. Why has this issue been largely ignored.
3. When will we see a vaccinated verses an unvaccinated study.
4. Why has the U.S. Vaccine Court made it difficult to prove obvious vaccine
injury
5. Why wasn’t Dr. Boyle of the CDC not prepared and did not have a clue about
the studies she was asked about the 2012 Autism Hearing?
6. Why is Poul Thorsen still at large after lying, embezzling and fleeing the
United States while his studies continues to be cited as the gospel truth?
7. Why is it ethical for vaccine-patent holder Dr. Paul Offit to be the nation’s go-
to guy when vaccines, autism and the vaccine-autism link hit
pharmaceutically-funded mainstream news sites?
This list of questions was compiled by Cathy Jameson in an a recent article.
Jameson, C. (2013). An autism mom show how easy it is to be a congressional
armchair advocate. Age of Autism. Retrieved from
http://www.ageofautism.com/2013/06/an-autism-mom-shows-how-easy-it-is-to-
be-a-congressional-armchair-advocate.html#comment-captcha
Here are some specific Questions I have regarding the science.
1. Why is it that when conducting vaccine safety data and efficiency trials they only
measure humoral immunity? In essence in Human trials they send the patients

2. home with diary cards to fill out and document anecdotal evidence and then draw
blood for antibody response. Seems like a simplistic view based on cell-mediated
immunity. I want to know the measured response of macrophages, natural killer
cells, cytotoxic T-lymphocytes because we know in an over abundance will cause
a cascade of inflammation leading to grades of encephalopathy. In the U.S. a
known table injury for vaccine adverse events is encephalopathy (HRSA, n.d.).
Yet there is no effort in knowing the chain reaction at the molecular level at least
by our health authority.
HRSA. (n.d). Vaccine injury table. U.S. Department of Health and Human
Services. Retrieved from
http://www.hrsa.gov/vaccinecompensation/vaccinetable.html
2. How does the body distinguish between a vaccine antigen and a naturally
occurring antigen? “Recognition of antigens in CNS parenchyma results in
retention of recruitment of T-lymphocytes, leading to inflammation. B-
lymphocytes probably also randomly traffic through the brain in a similar fashion
and, if they find specific antigens, they aggregate and produce IgG antibodies”
(Block et al, 2007).
Block ML, Zecca, Hong J-S. Microglia-mediated neurotoxicity: uncovering the
molecular mechanisms. Nat Rev Neuroscience 2007; 8:57-69. Retrieved from
http://www.ncbi.nlm.nih.gov/pubmed?term=%22Nature+reviews.+Neuroscience
%22[Jour]+AND+57[page]+AND+2007[pdat]
3. If antibodies trigger inflammation why are they not studying this in vaccine safety
trials?
4. Can the ingredients in vaccines trigger cell-mediated immunity? “Microglia cells
have receptors that enable them to sense damaged tissue and to recognize viruses,
environmental and endogenous toxins, and other pathogens. Such recognition
leads to upregulation (activation) of microglia cells” (Block et al, 2007).
This is what I find most disturbing.
“However, persistent activation of microglia has damaging effects and is thought
to contribute to the neurodegeneration that occurs in Alzheimer’s disease,
Parkinson’s disease, HIV encephalopathy, and other conditions. Microglial
activation also develops progressively with advancing age in absence of
stimulation” (Block et al 2007)
And this is specific with antigens.
“The most important of these cells are the perivascular monocytes, which reside
just outside the vascular basement membrane. These cells are the main antigen-
presenting cells of the CNS, thus playing an important role in immune reactions

3. involving the brain” (Block et al 2007).
So I ask you why isn’t this part of the safety analysis when studying vaccines?
Why are they just looking at one arm of immunity never bothering to see what
effects there are on the other? Especially because the risks of over-activation is so
damaging
Block ML, Zecca, Hong J-S. Microglia-mediated neurotoxicity: uncovering the
molecular mechanisms. Nat Rev Neuroscience 2007; 8:57-69. Retrieved from
http://www.ncbi.nlm.nih.gov/pubmed?term=%22Nature+reviews.+Neuroscience
%22[Jour]+AND+57[page]+AND+2007[pdat]
5. Innate immunity comes first, neutrophils, basophils, eosinophils, macrophages
(can act as a bridge to the adaptive immune response), dendritic cells (can act as a
bridge to the adaptive immune response). Adaptive Immunity (occurs second),
Humoral immunity, Th2 CD4+T cells, B Cells Cell Mediated Immunity, Th1
CD4+ T cells, CD8+T cells (also called Cytotoxic T cells). And there are other
cell types (e.g. Natural Killer Cells) and other “response profiles” (e.g. Th17).
Why isn’t this entire process studied during vaccine safety trials?
6. I would like to ask specifics on cell-production thru specific cell activations. (A)
Antigen/Pathogen/Toxin presents itself in the CNS. (B) The cell-mediated (T-
Cell) immune system is activated. (C) Cytotoxic cells, (IFN)-y, (TNF)-a, (IL)-6,
IL-10 and macrophages are produced when T cells (cell mediated immunity) is
activated.
This is how it’s described in MedScape: “These cytokines are produced by
activated T cells and histiocytes that infiltrate all tissue and lead to tissue necrosis
and organ failure” (Ravelli, 2012).
Ravelli, A. (2012). Macrophage Activation Syndrome. Medscape. Retrieved from
http://emedicine.medscape.com/article/1380671-overview#a0104
7. So again why isn’t this area of the immune system included in safety analysis?
When you assault the brain repeatedly in utero and after delivery with neuro-
toxins, antigens and pathogens hoping to get good antibody uptake rates to
combat against infectious disease? What is that doing to the cell-mediated system
that produces or activates cytokines that are known to cause neuro deterioration,
encephalopathy, AZ to name a few disorders?
8. Can we discover the mechanism and design protocols to protect those with
increased risks? Here is a CDC report that outlines the systemic reactions in
greater detail:

4. CDC. (1996). Update: vaccine side effects, adverse reations, contraindications,
and precautions recommendations of the advisory committee on immunization
practices (ACIP). MMWR. Retrieved from
http://www.cdc.gov/mmwr/preview/mmwrhtml/00046738.htm
9. Why isn’t the HHS doing a better job offering General Pediatrician’s training on
how to better pre-screen their patients who have mitochondrial disease (MD)
which is known to increase the risk of vaccine adverse events that result in an
autism diagnosis?
According to the government expert witness of Hannah Poling case, Dr. Andrew
Zimmerman, M.D. Pediatric Neurologist, “The cause for regressive
encephalopathy in Hannah at age 19 months was underlying mitochondrial
dysfunction, exacerbated by vaccine-induced fever and immune stimulation that
exceeded metabolic energy reserves. This acute expenditure of metabolic
reserves led to the permanent irreversible brain injury. Thus, if not for this event,
Hannah might have led a normal full productive life. Presently, I predict Hannah
will have a normal lifespan but with significant lifelong disability” (Zimmerman,
2007).
Zimmerman, A. (2007). Hannah Poling (DOB: 12/27/98); Report of the Office of
Special Masters, United States Court of Federal Claims, November 9, 2007.
Kennedy Krieger Institute. Retrieved from
http://www.scribd.com/doc/115393727/Andrew-Zimmerman-Poling-v-HHS-
Exhibit-3
There is an associated prevalence of MD and autistics.
Frye et al. (2013). Unique acyl-carnitine profiles are potential biomarkers for
acquired mitochondrial disease in autism spectrum disorder. Translational
Psychiatry. Retrieved from
http://www.nature.com/tp/journal/v3/n1/full/tp2012143a.html
Excerpt: “Autism spectrum disorder (ASD) has been associated with
mitochondrial disease (MD). Interestingly, most individuals with ASD and MD
do not have a specific genetic mutation to explain the MD, raising the possibility
of that MD may be acquired, at least in a subgroup of children with ASD”