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Prepared by:
Peshang Hassan
Ebola
The Deadliest Disease
August, 2016
• Introduction
• Classification
• Ebola virus Ecology and Transmission
• Sign and Symptoms
• Lab diagnoses
• Prevention
• Treatment
Outline
Introduction
Ebola Virus is a notoriously deadly virus that
causes fearsome symptoms, the most prominent
being high fever and massive internal bleeding.
Ebola virus kills as many as 90% of the people it
infects. It is one of the viruses that is capable of
causing hemorrhagic (bloody) fever.
Classification
Laboratory Diagnoses
Timeline of Infection Diagnostic tests available
Within a few days after symptoms begin
•Antigen-capture enzyme-linked immunosorbent
assay (ELISA) testing
•IgM ELISA
•Polymerase chain reaction (PCR)
•Virus isolation
Later in disease course or after recovery •IgM and IgG antibodies
Retrospectively in deceased patients
•Immunohistochemistry testing
•PCR
•Virus isolation
Sign and Symptoms
 During the incubation period, (2 to 21 days)
, symptoms include:
• Arthritic pain
• Backache (low-back pain)
• Chills
• Diarrhea
• Fatigue
• Fever
• Headache
• Nausea
• Sore throat
• Vomiting
 Late symptoms include:
• Bleeding from eyes, ears, and nose
• Bleeding from the mouth and rectum (gastrointestinal
bleeding)
• Depression
• Eye inflammation (conjunctivitis)
• Genital swelling
• Increased feeling of pain in skin
• Rash over the entire body that often contains blood (
hemorrhagic)
• Roof of mouth looks red
• Seizures, coma, delirium
Prevention
• Wash your hands
• Avoid contact with anyone you believe is infected
• Disinfect any potentially infected areas
• Do not touch bats, chimpanzees, gorillas or
monkeys
• Avoid dead bodies
• Avoid travelling to affected countries
• Use condoms
Treatment
There is no approved vaccine or medicine (e.g., antiviral drug) is available for Ebola.
Symptoms of Ebola and complications are treated as they appear. The following basic i
nterventions,
when used early, can significantly improve the chances of survival:
• Providing intravenous fluids (IV) and balancing electrolytes (body salts).
• Maintaining oxygen status and blood pressure.
• Treating other infections if they occur.
Also, experimental vaccines and treatments for Ebola are under development, but they
have not yet been fully tested for safety or effectiveness.
Conclusion
Finally, Ebola virus is one of the dangerous virus in the
world because it infects human easily through the
inhalation, the most dangerous way is transmission
among people. Also most severe clinical features to diag
nose this virus are bleeding internally and externally. If s
omeone seeing has Ebola symptoms, it is necessary to
take him or her immediately to the hospital because if he
or she not treated he or she will die in immediately.
References
Ebola (Ebola Virus Disease).Centers for Disease control and prevention. April 14,2016.
http://www.cdc.gov/vhf/ebola/outbreaks/history/chronology.html
Ebola (Ebola Virus Disease).Centers for Disease control and prevention. July 22,2016.
http://www.cdc.gov/vhf/ebola/treatment/
Ebola virus disease. World Health Organization. January,2016.
http://www.who.int/mediacentre/factsheets/fs103/en/
Ebola (Ebola Virus Disease).Centers for Disease control and prevention. February 18,2016.
http://www.cdc.gov/vhf/ebola/about.html
You

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Deadliest Disease Ebola

  • 1. Prepared by: Peshang Hassan Ebola The Deadliest Disease August, 2016
  • 2. • Introduction • Classification • Ebola virus Ecology and Transmission • Sign and Symptoms • Lab diagnoses • Prevention • Treatment Outline
  • 3. Introduction Ebola Virus is a notoriously deadly virus that causes fearsome symptoms, the most prominent being high fever and massive internal bleeding. Ebola virus kills as many as 90% of the people it infects. It is one of the viruses that is capable of causing hemorrhagic (bloody) fever.
  • 5.
  • 6. Laboratory Diagnoses Timeline of Infection Diagnostic tests available Within a few days after symptoms begin •Antigen-capture enzyme-linked immunosorbent assay (ELISA) testing •IgM ELISA •Polymerase chain reaction (PCR) •Virus isolation Later in disease course or after recovery •IgM and IgG antibodies Retrospectively in deceased patients •Immunohistochemistry testing •PCR •Virus isolation
  • 7. Sign and Symptoms  During the incubation period, (2 to 21 days) , symptoms include: • Arthritic pain • Backache (low-back pain) • Chills • Diarrhea • Fatigue • Fever • Headache • Nausea • Sore throat • Vomiting  Late symptoms include: • Bleeding from eyes, ears, and nose • Bleeding from the mouth and rectum (gastrointestinal bleeding) • Depression • Eye inflammation (conjunctivitis) • Genital swelling • Increased feeling of pain in skin • Rash over the entire body that often contains blood ( hemorrhagic) • Roof of mouth looks red • Seizures, coma, delirium
  • 8. Prevention • Wash your hands • Avoid contact with anyone you believe is infected • Disinfect any potentially infected areas • Do not touch bats, chimpanzees, gorillas or monkeys • Avoid dead bodies • Avoid travelling to affected countries • Use condoms
  • 9. Treatment There is no approved vaccine or medicine (e.g., antiviral drug) is available for Ebola. Symptoms of Ebola and complications are treated as they appear. The following basic i nterventions, when used early, can significantly improve the chances of survival: • Providing intravenous fluids (IV) and balancing electrolytes (body salts). • Maintaining oxygen status and blood pressure. • Treating other infections if they occur. Also, experimental vaccines and treatments for Ebola are under development, but they have not yet been fully tested for safety or effectiveness.
  • 10. Conclusion Finally, Ebola virus is one of the dangerous virus in the world because it infects human easily through the inhalation, the most dangerous way is transmission among people. Also most severe clinical features to diag nose this virus are bleeding internally and externally. If s omeone seeing has Ebola symptoms, it is necessary to take him or her immediately to the hospital because if he or she not treated he or she will die in immediately.
  • 11. References Ebola (Ebola Virus Disease).Centers for Disease control and prevention. April 14,2016. http://www.cdc.gov/vhf/ebola/outbreaks/history/chronology.html Ebola (Ebola Virus Disease).Centers for Disease control and prevention. July 22,2016. http://www.cdc.gov/vhf/ebola/treatment/ Ebola virus disease. World Health Organization. January,2016. http://www.who.int/mediacentre/factsheets/fs103/en/ Ebola (Ebola Virus Disease).Centers for Disease control and prevention. February 18,2016. http://www.cdc.gov/vhf/ebola/about.html
  • 12. You