This case review summarizes the surgical treatment of a 64-year-old female patient with degenerative lumbar scoliosis, spondylolisthesis, and flatback syndrome. She presented with a 28 degree lumbar curvature, flatback deformity, and spondylolisthesis. Her condition caused severe pain and disability. The surgical strategy involved segmental spinal instrumentation from L1 to the sacrum, posterior spinal fusion from L1 to S1, osteotomies from L1 to S1 to correct the deformity, and decompression of spinal stenosis. Post-operatively, her X-rays showed excellent alignment and core exercises provided pain relief, allowing for improved function.