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Pt. RAVISHANKAR SHUKLA UNIVERSITY
RAIPUR, CHATTISGARH
CENTER FOR BASIC SCIENCES
Corona Virus
By- David Sonwani
Guided By-
Dr. Veena Thakur
CONTENTS
•Introduction
•Types
•Outbreaks
•Current Scinerio
• Symptoms and Treatment
• Precautions
•MAP Showing Different Corona
viruses across China
• Genus of the Coronaviridae family .
•Positive-strand RNA viruses.
•The largest viral genome of all RNA viruses (27–32 kb).
•The genomic RNA is capped, polyadenylated and covered with nucleocapsid
proteins.
•Enveloped and carries large spike glycoproteins(seems like crown).
•The structural gene region, which covers the 3 part of the genome, encodes the
canonical set of structural protein genes in the order 5 - spike (S) - envelope (E) -
membrane (M) and nucleocapsid (N) – 3.
•The structural proteins are translated from subgenomic mRNAs. These
subgenomic mRNAs are the result of discontinuous transcription, a hallmark of
CoV gene expression.
26 GenomeBasedCoV Strains
Types
Symptoms And Transmission
2
Infection Spreading Cases Till 22 Feb 2020 As Per WHO
SARS-CoV-2 MERS-CoV SARS-CoV
Demographic
Detection date
December
2019 June 2012 November 2002
Detection place Wuhan, China
Jeddah, Saudi
Arabia
Guangdong,
China
Age average 49 56 39.9
Age range 21–76 14–94 1–91
Male:female ratio 2.7:1 3.3:1 1:1.25
Confirmed cases 835 2494 8096
Case fatality rate 25 (2.9%) 858 (37%) 744 (10%)
Health-care
workers 16 9.8% 23.1%
Sympto
ms
Fever 40 (98%)
98
% 99–100%
Dry cough 31 (76%)
47
% 29–75%
Dyspnoea 22 (55%)
72
% 40–42%
Diarrhoea 1 (3%)
26
% 20–25%
Sore throat 0
21
% 13–25%
Ventilatory support 9.8%
80
% 14–20%
Comparitive Stats of most
Deadly Corona Virus
Facts About Corona Virus
2
Map Showing Different Corona Viruses
Corona virus nCoV2019 and SARS

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Corona virus nCoV2019 and SARS

  • 1. Pt. RAVISHANKAR SHUKLA UNIVERSITY RAIPUR, CHATTISGARH CENTER FOR BASIC SCIENCES Corona Virus By- David Sonwani Guided By- Dr. Veena Thakur
  • 2. CONTENTS •Introduction •Types •Outbreaks •Current Scinerio • Symptoms and Treatment • Precautions •MAP Showing Different Corona viruses across China
  • 3. • Genus of the Coronaviridae family . •Positive-strand RNA viruses. •The largest viral genome of all RNA viruses (27–32 kb). •The genomic RNA is capped, polyadenylated and covered with nucleocapsid proteins. •Enveloped and carries large spike glycoproteins(seems like crown). •The structural gene region, which covers the 3 part of the genome, encodes the canonical set of structural protein genes in the order 5 - spike (S) - envelope (E) - membrane (M) and nucleocapsid (N) – 3. •The structural proteins are translated from subgenomic mRNAs. These subgenomic mRNAs are the result of discontinuous transcription, a hallmark of CoV gene expression.
  • 4.
  • 6.
  • 8.
  • 9. 2 Infection Spreading Cases Till 22 Feb 2020 As Per WHO
  • 10.
  • 11. SARS-CoV-2 MERS-CoV SARS-CoV Demographic Detection date December 2019 June 2012 November 2002 Detection place Wuhan, China Jeddah, Saudi Arabia Guangdong, China Age average 49 56 39.9 Age range 21–76 14–94 1–91 Male:female ratio 2.7:1 3.3:1 1:1.25 Confirmed cases 835 2494 8096 Case fatality rate 25 (2.9%) 858 (37%) 744 (10%) Health-care workers 16 9.8% 23.1% Sympto ms Fever 40 (98%) 98 % 99–100% Dry cough 31 (76%) 47 % 29–75% Dyspnoea 22 (55%) 72 % 40–42% Diarrhoea 1 (3%) 26 % 20–25% Sore throat 0 21 % 13–25% Ventilatory support 9.8% 80 % 14–20% Comparitive Stats of most Deadly Corona Virus
  • 13. 2 Map Showing Different Corona Viruses