Probably one of the most controversial topics among urologist. Who to treat and how to treat.
This is the effect of foreskin. Children are beginning to potty-train- dysfunctional voiding.
Unlike adults, we have to more perceptive about symptoms. Do not present with dysuria, supra pubic pain. Hematuria on dipstick. Children present diferently at different ages.
UTI is a generic term. We try to localize the infection to determine our course of investigation with imaging, and treatment. Bladder infections are low grade temperature, goes down with tynelol.
High grade temperature.
Other routes hematogenous, lymphatic but the most common is ascending route. Why girls are more at risk than boys,
E. Coli most common organism. Over 150 strains, fewer than 10 account for the majority of the cases. It relates to the virulence factor. 91% E.coli causing pyelo have the fimbriae.
Breast feeding have some protective effect. Most important easiest to perform is good voiding habits. Do not ask the child when to void, put on a schedule. Fast flowing river clear versus a stagnant pool. Doubling time every 40 minutes.
So who are at risk for UTI’s. Reflux, PUV, duplicated ureters. Immunocompromise, neurogenic bladder.
Look for some clues in the history and physical.
Most common are gram negative enteric bacteria.
The goals of treatment is two fold. Certainly early detection, imaging have dramatically reduced the long-term sequelae.
Widespread use of DMSA technetium 99 dimercaptosuccinic acid with febrile uti’s up to 50% 2 to 2 years later show scarring. Next slide an example of DMSA.
Any photopenic areas are scarred, non functioning nephrons. What are the chances of renal scarring?
What to look on a office dipstick since few places do direct microscopic analysis.
Bagged is good a ruling out a UTI, not useful in documenting one. SP is the gold standard.