RBC Disorders - case studies
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Cases on RBC disorders specially designed for UG medical students. To know the correct answers to theses cases contact the author <csbrprasad>
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RBC Disorders - case studies
- 1. CASE STUDIES in RBC Disorders Dr.CSBR.Prasad, M.D., v1-CSBRP-Nov-2012
- 2. Case-1 • 8month old infant with 2week history of swollen hands and feet v1-CSBRP-Nov-2012
- 4. Case-1 Peripheral blood smear v1-CSBRP-Nov-2012
- 5. Case-1 1. What are the x-ray findings? 2. How do you describe the hand? 3. What is the abnormality in the peripheral smear? 4. How do you confirm your diagnosis? 5. How do you prevent future recurrent complications of this disease? v1-CSBRP-Nov-2012
- 6. Case-2 • 29yo male. Incidental finding in routine hemogram. What is your interpretation? v1-CSBRP-Nov-2012
- 8. Case-2 • How do you confirm your suspicion? v1-CSBRP-Nov-2012
- 9. Case-3 • 60yo male with weakness and pallor. • Hemogram and PBS are given for your interpretation. v1-CSBRP-Nov-2012
- 11. Case-3 PBS v1-CSBRP-Nov-2012
- 12. Case-3 1. What are the significant abnormal values in hemogram report? 2. What are your PBS findings? 3. What is your diagnosis? 4. What do you do next? v1-CSBRP-Nov-2012
- 13. Case-4 • 60yo female with chronic severe joint pains and deformity was found to have HGB=8gm/dl, MCV=68fl, serum iron=100µg/dl • Peripheral smear and BM are given for your interpretation v1-CSBRP-Nov-2012
- 15. Case-4 PBS v1-CSBRP-Nov-2012
- 16. Case-4 BM, Perl’s stain v1-CSBRP-Nov-2012
- 17. Case-4 1. How do you describe the appearance of the hand ? 2. Describe the peripheral blood smear 3. What is being demonstrated in the Bone marrow smear? Is it normal or altered? 4. What is your diagnosis? 5. What is the basic pathology in this disease? 6. What should be the main stay of treatment? v1-CSBRP-Nov-2012
- 18. Case-5 • 40yo female with weakness and very mild jaundice and recent onset foot drop • Hemogram and PBS and BM images are given for your interpretation v1-CSBRP-Nov-2012
- 19. Case-5 Hemogram v1-CSBRP-Nov-2012
- 20. Case-5 PBS v1-CSBRP-Nov-2012
- 21. Case-5 BM v1-CSBRP-Nov-2012
- 22. Case-5 BM v1-CSBRP-Nov-2012
- 23. Case-5 BM v1-CSBRP-Nov-2012
- 24. Case-5 BM v1-CSBRP-Nov-2012
- 25. Case-5 1. What are the striking abnormalities in hemogram values? 2. What are your findings in PBS, BM smears? 3. Why this patient has foot drop? 4. How do you assess the response to treatment in these cases? 5. How do you explain jaundice in this patient? v1-CSBRP-Nov-2012
- 26. Case-6 • 35yo female with chronic anemia and whitish skin lesions and indigestion • Gastric biopsy was done v1-CSBRP-Nov-2012
- 27. Case-6 Skin lesions v1-CSBRP-Nov-2012
- 28. Case-6 Section from stomach v1-CSBRP-Nov-2012
- 30. Case-6 1. Enumerate the histological findings in stomach biopsy 2. What are the PBS findings? 3. What is your diagnosis? 4. What is the importance of finding shown in the clinical photograph of the patient? v1-CSBRP-Nov-2012
- 31. Case-7 • 40yo male patient complains of passing red colored urine after consuming beans shown in the image. v1-CSBRP-Nov-2012
- 33. Case-7 B - Patient’s urine sample A - Normal urine for comparison v1-CSBRP-Nov-2012
- 34. Case-7 PBS v1-CSBRP-Nov-2012
- 35. Case-7 Reticulocyte preparation v1-CSBRP-Nov-2012
- 36. Case-7 1. Describe the abnormality in urine sample 2. What are your findings in retic prep? 3. Describe the typical cells shown in the peripheral blood 4. How do you confirm the diagnosis? 5. Which famous mathematician suffered from this disease? v1-CSBRP-Nov-2012
- 37. Case-8 Urine samples from a patient What is your diagnosis? v1-CSBRP-Nov-2012
- 38. Case-9 • 18yo boy with h/o jaundice since birth • Operated for Gall stones recently • Sectioned gall bladder and PBS images are given for your interpretation v1-CSBRP-Nov-2012
- 40. Case-9 PBS v1-CSBRP-Nov-2012
- 41. Case-9 1. What are your findings in the gall bladder? 2. What are your findings in the peripheral smear? 3. What is your diagnosis? 4. What test will help in establishing the diagnosis? 5. What one may find in the abdominal examination? 6. Name some other causes for PBS findings 7. What are the other causes for gall bladder findings 8. Can you name some causes for “jaundice since birth” 9. After what period “neonatal jaundice” becomes worrysome? v1-CSBRP-Nov-2012
- 42. Case-10 Patient’s spun blood sample and micro-HCT tubes (Arrows). What are the causes for such a finding? v1-CSBRP-Nov-2012
- 43. Case-11 • Child with chronic microcytic hypochromic anemia • Blood and BM images are given v1-CSBRP-Nov-2012
- 44. Case-11 PBS & BM v1-CSBRP-Nov-2012
- 46. Case-11 1. What is your diagnosis? 2. What are the differentials for microcytic hypochromic anemia? v1-CSBRP-Nov-2012
- 47. Case-12 • A child with hemolytic anemia • After a brief illness his anemia worsened • Clinical image, BM pictures are given for your interpretation v1-CSBRP-Nov-2012
- 49. Case-12 BM v1-CSBRP-Nov-2012
- 50. Case-12 BM aspirate v1-CSBRP-Nov-2012
- 51. Case-12 BM biopsy v1-CSBRP-Nov-2012
- 52. Case-12 • What are the BM findings? • How do you treat these cases? v1-CSBRP-Nov-2012
- 53. Case-13 • 40 yo female with muscle weakness and anterior mediastinal tumor • Chest CT and BM images are given for interpretation v1-CSBRP-Nov-2012
- 54. Case-13 Chest CT v1-CSBRP-Nov-2012
- 55. Case-13 BM v1-CSBRP-Nov-2012
- 56. Case-13 BM v1-CSBRP-Nov-2012
- 57. Case-13 1. What are the CT findings? 2. Name some DDs for anterior mediastinal mass 3. What are the BM findings? 4. What is your diagnosis? 5. How do explain muscle weakness in this patient? 6. What are the other causes for this type of BM changes? v1-CSBRP-Nov-2012
- 58. Case-14 15yo female with chronic anemia v1-CSBRP-Nov-2012
- 59. Case-14 PBS v1-CSBRP-Nov-2012
- 60. Case-14 1. What is the descriptive term used for the facial appearances in this case? 2. Describe the changes in skull X-ray? 3. What are the findings in peripheral blood smear? 4. What is your diagnosis? 5. How do you confirm the diagnosis? v1-CSBRP-Nov-2012
- 61. Case-15 50yo male with a HGB=11gm/dl. PBS given for your interpretation. v1-CSBRP-Nov-2012
- 62. Case-16 How do you prove it’s hereditary? v1-CSBRP-Nov-2012
- 63. Case-17 Paleopathology case Skull from Italian excavation site v1-CSBRP-Nov-2012
- 64. Case-17 Clue: Bottom image v1-CSBRP-Nov-2012
- 65. Case-17 Paleopathology case 1. Describe the abnormality seen in the skull 2. What are the causes for such changes 3. How do you interpret the findings in the bottom image 4. What is your probable diagnosis? v1-CSBRP-Nov-2012
- 67. Please make an attempt to get the right answers For answers contact: Dr.CSBR.Prasad, M.D., Associate Professor, Deptt. of Pathology, Sri Devaraj Urs Medical College, Kolar-563101, Karnataka <CSBRPRASAD@rediffmail.com> v1-CSBRP-Nov-2012