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Cord Blood Banking Pros
When making any decision regarding a child's future, any parent would (presumably) opt for a
choice that increases the child's chances for health and well being. In recent years parents have been
offered the option to save umbilical cord blood. This procedure has become known as cord blood
banking. Cord blood banking has been discovered to offer many ways to help ensure not only the
child's health, but in some cases, other members of the family as well. Cord blood banking offers a
plethora of health benefits that can save a child and their family from suffering the devastating
effects of many diseases. Cord blood could, in many cases, essentially save your child's life.
So what is cord blood banking? Cord blood banking is the process of storing the stem cell–rich
blood from the umbilical cord after a mother gives birth. The stem cells are the key that unlock
potential for treatment for conditions such as brain and spinal cord injury, some types of cancer,
including leukemia, brain and heart tissue repair, and many others (2015). One of the reasons that
there is such a positive success rate when using cord blood for these medical conditions is that for
the child, the stem cells are a 100% match. (GET MORE DATA REGARDING WHY THE BLOOD
IS ... Show more content on Helpwriting.net ...
Firstly, the child's stem cell–rich blood is stored indefinitely, and available when/if the child or other
family member may benefit from its use. Instead of a donor having to undergo painful bone marrow
transplants, with a chance of it not being successful, cord blood can be used. As mentioned, since it
would be a 100% match to the child, there would be very little likeliness of his/her body rejecting
the transplant. In some instances, the cord blood could be used to treat a sibling or other family
member (depending on the condition). Lastly, the peace of mind derived from knowing that you
have taken a viable, (REWORD) to ensure your child's future health and
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The Treatment Of Stem Cell Therapy
Stem cell therapy, also known as regenerative medication, has been an increasingly utilized therapy
in recent years. The cells added to the body interact with the surrounding body, making the
regenerative process available to begin the healing process of the cells at the site (R. (2014)). These
therapies are used to heal common sport injuries such as a knee injury, diseases, arthritis, and many
other crippling effects that may occur in the human body (R. (2014)). Many of the stem cells that are
used from the therapies can come from bone marrow, fat,and blood from the patient or even cells
from more controversial areas such human embryos. Stem cell therapy has shown a lot of promising
effects, not only outshining the effects of prescription medicine given out to patients from doctors,
but it has also shown that the therapy has long term effects than a steroid would have had.
Stem cell therapy is important because it has given hope to several people with common illnesses
such as arthritis, knee pains, and back pains by regenerating their cells to realize the pain that they
are in. Most of the patients who come in for sport related injuries are professional athletes.Most of
the time these athletes are the ones who have obtained a knee injury in basketball or football and are
resorting the use of a steroid to try to fix the pain, but soon realize that it is not a long–lasting effect.
This is where stem cell therapy comes into play. Chris Johnson from the New York Jets was one
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Focal Nervous System Paper
The general structure of the nervous system is known as the "anatomy of the nervous system"
(neuroanatomy). The acts of human beings are guided by controls through the nervous system. A
human being's response to its environment is also through controlled guiding and thoughts (Pinel,
2013). The peripheral nervous system or PNS and central nervous system or CNS are important
parts of our nervous systems within hollow tube holding the CNS and PNS of our nervous system
(Pinel, 2013). There are subdivisions of these two sensory systems that have structure and
capacities. Focal Nervous System: AS the name recommends, it is focal and the two primary
segments of the focal sensory system are mind and spinal rope, which are under the assurance of
exceptional
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Stem Cell Type Is Best?
Topic: Stem research, which stem cell type is best? Umbilical cord stem cells or embryonic stem
cells.
General Purpose: To inform
Specific Purpose: To inform the audience of the advantages and disadvantage of using embryonic
and umbilical cord stem cells in research.
Central Ideal: While medical researchers believe that the use of embryonic stem cells is their best
option in research, others believe it to be unethical and immoral, and that umbilical stem cells are a
good alternative to embryonic stem cells.
Organizational pattern: Topical
I. Introduction:
A. Attention Getter: Some believe that murder is committed each day in the name of science.
B. Reveal Topic: While medical researchers believe that the use of embryonic stem cells is their best
option in research, others believe it to be unethical and immoral that umbilical stem cells are a good
alternative to embryonic stem cells.
C. Audience Motivation: Every person will be or has been touched by cancer, diabetes, arthritis,
Alzheimer's or some other devastating disease during their life time. Would you support any means
of research to find a cure that may end human suffering even if it meant death of a human?
D. Qualifications/Credibility: After must reading and research of the stem cell issue, I am qualified
to speak about the pros and cons of using embryonic stem cells and umbilical (adult) cord stem
cells.
E. Purpose and Preview: I am here to present the pros and cons of embryonic stem cells verses
umbilical
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The Ultimate Life Insurace Policy--Cord Blood Essay
Over the last several decades, the field of medical technology and research has become increasingly
advanced. Just read up on any of the most recent innovations; what may have once been considered
science fiction is rapidly becoming reality. Some of the most publicized scientific discoveries are
related to stem cells, as the controversial research and use of certain types of these cells is
continuously being debated among politicians, scientists, and religious leaders. However, it is
believed that a specific type of stem cell, an umbilical cord blood stem cell, may be used to treat a
number of diseases, disorders, or injuries devoid of ethical controversy. Banks for storing cord blood
exist in countries all over the world and its use is ... Show more content on Helpwriting.net ...
The first type of stem cell, an embryonic stem cell, is known for being able to continuously multiply,
as well as for being pluripotent. They can be "derived in vitro from the blastocyst of an embryo
usually left over from in vitro fertilization" (Forraz & McGuckin, 2011, p.61). Unlike other types of
stem cells, embryonic stem cells have yet to be used in any kind of clinical treatment of patients.
The high risks of "immune rejection" or "teratoma formation" are serious obstacles (Harris, 2009,
p.182). The second type of stem cell, adult stem cells, is primarily considered to be multipotent and
may be found in "specific adult human tissues" such as the skin or bone marrow, just to name a few.
Over the last twenty years, the amount of scientific research and trials using adult stem cells has
grown significantly, despite their lower potency than embryonic stem cells (Forraz & McGuckin,
2011, p.61). Lastly, cord blood stem cells, are technically considered to be a special type of adult
stem cell, but their youthful properties give them "greater restorative and regenerative potential."
Directly following the birth of a child, these stem cells can be collected from the blood in the
umbilical cord (Steenblock & Payne, 2006, p.9). Embryonic, adult, and cord blood stem cells
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Brain Disorders: What Is Cerebral Palsy?
What is Cerebral Palsy?
Cerebral palsy is a general term for a variety of disorders caused by damage to the brain. The
damage occurs before or during birth or in the first few years of life. The brain damage may cause
severe crippling, or the symptoms may be so mild that they hardly interfere with the patient's
activities.
There are several types of cerebral palsy, and all involve lack of muscle control. Common effects of
the disorder include a clumsy walk, lack of balance, shaking, jerky movements, and unclear speech.
In many patients, the brain damage also causes intellectual disability, learning disability, seizures,
and problems in sight and hearing. About half of 1 percent of the people in the world have cerebral
palsy.
What are the causes?
In most cases, the causes of faulty growth of the brain that result in cerebral palsy cannot be
determined. In some cases, however, brain damage may result from illness in the mother during
pregnancy. For example, rubella can severely harm an unborn child, even though the mother may
have had only mild symptoms or none at all during pregnancy. Cerebral palsy is rarely an inherited
trait.
Brain damage can also occur during the birth process, especially in premature births. In babies born
after a normal term of pregnancy, brain damage may ... Show more content on Helpwriting.net ...
These types are (1) ataxic, (2) athetoid, (3) hypotonic, and (4) spastic. In the ataxic form, the
patient's voluntary movements are jerky, and a loss of balance is suffered. In the athetoid type, the
person's muscles move continually. These movements prevent or interfere greatly with voluntary
actions. A person with hypotonic cerebral palsy appears limp. The person can move little or not at all
because the muscles cannot contract. Spastic cerebral palsy patients have stiff muscles and cannot
move some body parts. A person with cerebral palsy may have more than one muscle disorder. The
person may be only slightly disabled or completely
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Making Positive Changes For Expectant Parents
Within this essay, I will reflect on an event that I witnessed during clinical placement, focussing on
the process of non–directed donation (RCOG, 2006) of umbilical cord blood via the onsite NHS
Blood and Transport (NHSBT) team, as well as the related issue with the antenatal communication
and subsequent consent to utilise the service. In order to maintain confidentiality in accordance with
the Nursing and Midwifery Council's Code of Conduct (NMC, 2008) and The Data Protection Act
(1998), the hospital and the people involved in the event, (as well as those involved in subsequent
conversations as a result) will not be referred to by name. I have used the Gibbs reflective cycle
(Gibbs, 1988), and will be relating the event back to recent research and relevant hospital and
governmental procedures wherever possible. As a result of this assignment, I have undertaken
further research that will be outlined below, which I hope will assist in making positive changes for
expectant parents in the future.
Donation of umbilical cord blood is a trend that has grown in popularity in recent years, and is now
offered on site at several NHS trust hospitals (RCOG, 2006). Despite this service being readily
available to expectant parents within my placement hospital, it became clear during my second week
that the relevant information regarding donation was not being provided soon enough in the
antenatal period which would allow for an informed decision to be made as to whether or not
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Autonomic Dysreflexia Research Paper
What is Hyperreflexia?
Hyperreflexia, also known as autonomic dysreflexia, is a state that is unique to patients after spinal
cord injury at a T–5 level and above. Patients with spinal cord injuries at Thoracic 5 (T–5) level and
above are very susceptible. Also patients at Thoracic 6 – Thoracic 10 (T6–T10) may be susceptible.
Patients with Thoracic 10 (T–10) and below are usually not susceptible. Also, the older the injury
the less likely the person will experience autonomic dysreflexia.
Hyperreflxia can develop suddenly, and is a possible emergency situation. If not treated promptly
and correctly, it may lead to seizures, stroke, and even death Autonomic dysreflexia means an over–
activity of the Autonomic Nervous System. It can occur ... Show more content on Helpwriting.net ...
Perform a digital stimulation and empty your bowel. If you are performing a digital stimulation
when the symptoms first appear, stop the procedure and resume after the symptoms subside.
If your bladder or bowel are not the cause, check to see if:
 You have a pressure sore
 You have an ingrown toenail
 You have a fractured bone If you are unable to find the stimulus causing autonomic dysreflexia,
or your attempts to receive the stimulus fail, you need to obtain emergency medical treatment. Since
not all physicians are familiar with autonomic dysreflexia (hyperreflexia) and its treatment, you
should carry a card in your billfold that describes the condition and the treatment required.
How can you prevent Hyperreflexia? Prevention of autonomic dysreflexia is very important.
Following are precautions you can take which may prevent episodes:
If you have an indwelling catheter:
 Keep the tubing free of kinks
 Keep the drainage bags empty
 Check daily for grits (deposits) inside of the catheter.
If you are on an intermittent catheterization program, catheterize yourself as often as necessary to
prevent
... Get more on HelpWriting.net ...
Spinal Cord Injury Research Paper
vThe spinal cord is well–protected anatomically with barriers, vertebra, muscles of the back, and the
meninges. A considerable force is required to cause trauma to the neural tissue of the spinal cord.
This can be laceration or maceration by a sharp penetrating object; contusion or compression, the
most common form of spinal cord injury; or infarct by vascular insult. All of these injury forces
begin the process of tissue destruction we term the primary injury.
These mechanical forces predominately damage the central grey matter, due to its softer and highly
vascularised nature, causing massive loss of essential cells, including local neurons, astrocytes,
oligodendrocytes and endothelial cells in the vicinity of the injury site (Dumont et ... Show more
content on Helpwriting.net ...
This protein has been shown to activate the epidermal growth factor receptor (EGFR) thereby
inhibiting neurite outgrowth and axon regeneration (Schachtrup et al., 2007). In addition to plasma
proteins, there is invasion of blood circulating inflammatory cells into the spinal cord through the
disrupted BSB. Since spinal cord is considered as an immune–privileged or immunologically
quiescent site, the sudden influx of immune cells dramatically alters the regulation of the
inflammatory response in the injured spinal cord (Trivedi et al., 2006). This dysregulation of the
inflammatory response plays a major role in enlargement of tissue damage in the secondary phase of
the injury. As such, it is thought that the initial damage to the local blood vessels and BBB is
decisive for the disruption events that cause the secondary phase of injury (Mautes et al., 2000a,
Mautes et al.,
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Umbilical Cord Blood Harvesting
I. Introduction A. Attention getting opener: There is a critical need for effective, long–term solutions
for harvesting stem cells. Already there are "more than 300,000 units stored worldwide. These
products have been banked under stringent quality conditions, in order to ensure their safety and
efficacy," (Vladareanu, Mihailescu & Zvanca, 20070, p. 142). B. Credibility statement: Abundant
research shows that harvesting stem cells from umbilical cord blood offers crucial advantages over
other methods, including bone marrow and peripheral blood. C. Thesis: Although not an ideal
medium for harvesting, and will not replace other types of stem cell sources, umbilical cord blood
should be an integral part of the blood/tissue bank repertoire. II. Advantages of using umbilical cord
blood. A. Immunology 1. "Umbilical cord blood (UCB) contains stem and progenitor cells capable
of restoring haematopoietic and immunological function in vivo," (Navarette & Contreras, 2009, p.
236). 2. Umbilical cord blood stem cells "can be transplanted to regenerate a patient's immune
system," (Vladareanu, Mihailescu & Zvanca, 20070, p. 142). B. Pre–frozen/cryopreservation 1.
cryopreservation allows for the storage of stem cells for future use, eliminating need for searching
for suitable donor 2. Especially true when minorities need transplants (Samuel, et. Al, 2007). C.
Advantages over other forms of stem cell 1. Bone marrow cell harvesting "may be detrimental due
to the
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Essay Legalize Stem Cell Research
Stem cell research should be legal and funded by the government in all 50 states. There are several
types of stem cells that we have available to use for research. The controversy comes from the use of
Embryonic Stem Cells (ESC) and how they are obtained. The funding is very unstable for stem cell
research due to the use of ESC, combined with the message they send. There have been several
arguments in regards to the right to life. In–Vitro Fertilization (IVF) clinics have never been funded
by the government and that is not the plan for this research either. Even if the research was funded
by the government, the stem cells would continue to live on. Stem cells are used to find cures for
life threatening diseases. Research of stem cells is ... Show more content on Helpwriting.net ...
Somatic Stem Cells show they are resourceful and have been in use for a very long period of time,
Somatic Stem Cells can help cure disease. Without continued funding for this, researchers would be
unable to find other cures, like the already in process bone marrow transplants. The rejection rate
theory is very powerful, being able to save lives with low complications; however, if the research is
not funded, we might not be able to stop the person from getting the illness again, considering the
illness is most likely in the genetic makeup of the individual. Three is a need for continued funding
for this research, at least until researchers have exhausted all avenues, finding every possible
capability of these Somatic Stem Cells. The second type of stem cell in use is the Umbilical Cord
Blood Stem Cells. These stem cells come from the umbilical cord of a newborn which generally
would get discarded. Otherwise, these cords are frozen and stored in a private blood bank, in case
the stem cells should ever be needed by the donor or their family ("Umbilical Cord Blood", par. 23).
The processes to save these cells is; something like this, the parents pay a onetime fee and they
receive a package for sending the cord in after delivery, after the initial process the family pays an
annual storage fee to continue to
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Questions On Private Practice
Dilemma:
In the season 2 premier of Private Practice, we are introduced to a couple that have a sick son who
was dying of Acute Lymphoblastic Leukemia. They had a partial match donor to help save the son
life but unfortunately the partial match donor was found to have pneumonia. Because the doctors
thought the son had a donor they started to prepare him for the transplant by stripping his immune
system and unless he received the transplant within a week he would die. The parents had already
become pregnant with a genetic match to their son, so that they could use the baby's umbilical cord
blood in the future. The wife was 27 weeks pregnant when she and her husband request that Doctor
Addison induce her delivery to preform a C–section this ... Show more content on Helpwriting.net ...
If doctor Addison does this she can control how the C–section will work and she can have different
teams ready, one team to help with the umbilical cord transplant for the son, another team ready to
care for the premature baby, and one team to help the mother and finish the C–section. This would
allow for the son to receive the transplant, saving his life. But the premature baby must be carefully
cared since the chance of dying is high, she would need to be monitored and forced to stay in the
hospital for quite some time till fully development or approval from doctors.
Perspective number 2:
Another perspective for this case is that Doctor Addison does not preform the C–section. The sick
son would be placed back on the transplant list with the hope that they could find another donor
before the son dies. But most likely the son would die since he only had a week left to live.
Although, this wouldn't place the unborn baby at risk for complications due to being born
premature. The women was 6 months pregnant and the doctors were not concern of any risk, only
increasing the likeness of the couple having a healthy baby being born.
Perspective number 3:
Another possible perspective is for the mother carrying the baby to endure her own delivery such as
by breaking her own water. This puts the mother at risk because she has to induce her own delivery
without the knowledge of the proper way to
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Cord Blood Banking Essay
1. What is an umbilical cord blood banking and what role it plays in a stem cell research? Over the
past two decades, the stem cells became an important part of a medical research. Today, stem cells
are used to assist in treating numerous diseases. The umbilical cord blood can now be saved in
special banks to preserve the youngest stem cells for an unlikely event the child later develops a
certain kind of illness. Although there has been a lot of talk about research using stem cells, most
people don't come in contact with the topic of cord blood banking. This issue is exclusively
presented to expecting parents. I want to use this question to inform unfamiliar readers about cord
blood banking and its use in stem cells research. I intend to use this a question as an introduction to
this topic in my research essays. 2. How can the latest research in stem cells used from cord blood
and tissue banking support expectant parents' decision to save their baby umbilical cord blood? This
could also be a main topic question. This question can furthermore investigate my first question on
... Show more content on Helpwriting.net ...
They can also see the cord blood banks frequent advertisings in many expecting parents' magazines.
Unless the expecting parents do more research, very few learn about public cord blood banks. There
are advantages and disadvantages associated with each option. For example, the cost of a private
cord blood banking is still very high, but the cord blood stays availably exclusively to the client. The
public cord blood banks collect a cord blood by donation. Unfortunately, this option is not available
in every hospital and the donated cord blood may not be accessible by the original donor if needed.
This question is worth exploring further, and it also compliments the other two questions on this
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Biol101 Homework Assignment 2 Essay
B) Stem cells. A relative of a friend of yours had a spinal cord injury after a bad car accident. The
medical team has decided that this patient is a good candidate for a clinical trial using stem cell
therapy. Your friend has not had a biology course since high school, so you are going to write for
him or her a two–page discussion of stem cell information. In your discussion, include a description
of the biology of stem cells, and explain how these cells are unique in their ability to treat diseases
and injury. The following website from NIH regarding stem cell research will be very helpful:
http://stemcells.nih.gov/index.asp.
Before we determine how stem cells can treat various diseases including spinal cord injuries, let us
first ... Show more content on Helpwriting.net ...
Many wonder why the spinal cord is not able to heal itself like the other parts of the body such as
how the skin injured on a leg can regenerate and heal itself or how muscle can repairs itself is it gets
strained. But the spinal cord is different. That is because some of the cells in the central nervous
system are so complex and specialized that they do not have the ability to regenerate.
In come a stem cell which is an immature cell that can become a different cell, or even transform
into one of many different cells. Most stem cells can also renew or divide themselves indefinitely.
These two characteristics are what present a new pathway to repairing damage to the human body
caused by trauma, degeneration and disease. Stem cells keep on generating in the body and take
place of the cells which have died such as in a spinal cord injury. The process of using stem cells for
spinal cord injury is controversial for some and involves taking one's own bone marrow or a donated
human umbilical cord. A licensed anesthesiologist harvests bone marrow from both hips under light
general anesthesia in a hospital operating room, the procedure takes about one and half to two hours.
The bone marrow–derived stem cells have to pass rigorous testing for quality and to ensure there is
not bacterial contamination before they are administered to the patient. In the same fashion
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Cord Blood Research Paper
Cord Blood Banking is now a huge epidemic nationally. What was once considered to be medical
waste is now what is considered a medical breakthrough. Cord blood is stored in two types of banks,
both having their benefits and negative aspects. There are many benefits and positive aspects that
accompany the banking cord blood. Many of these benefits include but are not limited to the
treatment of many life threatening diseases and disorders such as cerebral palsy and childhood
cancer such as leukemia. With positives benefits there also come negative aspects. Many of these
include who can receive the transplant, the cost of cord blood, the simple fact that the child who the
blood came from may never be able to receive that cord blood, and also ... Show more content on
Helpwriting.net ...
Researchers have discovered that it is actually harder for adults to be treated with cord blood than
bone marrow. Children usually receive one unit of cord blood because their small bodies only need a
small amount. Adults however need more than the one unit of blood that children receive because
their bodies are so much bigger. According to eurostemcells.org there are serious complications of
receiveing to few of stem cells. A stem cell transplant containing not enough stem cells may fail or
could lead to slow creation of new blood in the body. Doctors have found that if they use two units
of cord blood, the transplant will work. When the cord blood is being collected, each newborn only
can provide one unit of blood, so when someone needs to receive more than one unit, doctors have
to find an almost identical match. There are also many controversies on whether or not cord blood
should be collected and banked. Many children's cord blood can't be used by the child who donated
it. The cord blood may be contaminated with cells that made that child sick. According to Parent's
Magazine "Both the American College of Obstetricians and Gynecologists (ACOG) and the
American Academy of Pediatrics (AAP) issued statements in the late 1990s opposing the use of for–
profit banks –– and criticizing their marketing tactics. Instead, they recommended that parents
donate cord blood to public banks, which make it available for free to anyone who
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Cord Blood Celligenics: A Case Study
I will request that my (Healthcare Professionals) doctors, midwifes and nurses collects the Cord
Blood using the Collection Kit provided by Celligenics.
I understand that, under normal circumstances, collection should never affect with the birthing
process and cause me no discomfort or pain.
I understand that there may be complications at birth that will make it impossible or challenging to
collect the Cord Blood, and for these reasons my Healthcare Professional will be enabled to refuse
to collect the Cord Blood.
I understand that there is a risk of bacterial and/or fungal contamination when collecting Cord
Blood. The contaminating bacteria and/or fungus is usually a naturally occurring contaminant of the
birthing canal. Celligenics
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Cord Blood Case Study
Michelle and Jayson Whitaker have been married for a couple of years. Michelle is 33 years and
Jayson is 35 years old. They always dreamed of having a happy family, in which they wanted to
have only one son. After one year of their marriage, god blessed them with one, whom they name
Charlie. Unfortunately, Charlie was diagnosed with a life threatening blood condition known as
Diamond Blackfan Anaemia. The Whitakers thought that the only solution to cure their one beloved
son was to have a sibling, a donor for Charlie. After the success of the Nash's family, they were
encouraged to screen embryos to give birth to a healthy child that would be a perfect cell match for
Charlie, so they applied for the allowance to do that. At first, the HFEA refused their request as
Charlie's condition is not genetic and such a technique will not do that much of a help. But the
Whitakers didn't give up and went to the USA were the policies are not as strict. After some
considerable stress, Jamie was born and was able to be a successful donor for Charlie by providing
umbilical cord blood. ... Show more content on Helpwriting.net ...
2– Do you think that it is ethical for the parents to agree on donating tissues as cord blood? 3– If
such a procedure required an invasive process that would harm the new child, what do you believe
the right thing to
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St. John Hospital Of Detroit On The Labor And Delivery Unit
My clinical rotations are at St. John Moross Hospital in the city of Detroit on the labor and delivery
unit. "St. John is a regional–referral teaching hospital with 772 licensed beds, a 1,200 member
medical staff and more than 50 medical and surgical specialties. It is also the largest acute–care
provider and a designated Emergency Trauma Center. St. John's service area consists of the city of
Detroit, and the counties of Wayne, Macomb and St. Clair Counties where over 80% of their
patients reside. The total population for this service area is 2,875,367 with slightly more males than
females. Also, 61.8% of the population is white, 28.6% is Black non–Hispanic, 4.3% Hispanic,
2.5% is Asian& Pacific Islander (non–Hispanic) and 2.7% are categorized as other" (Taueg, C,
2012). The goal of the health system is being committed to providing spiritually centered, holistic
care, which sustains and improves the health of individuals in the communities we serve, with
special attention to the poor and vulnerable. My OB clinical experience has been great! I have
gained a lot of experience and knowledge from my clinical professor and the nurses on the unit. I
have learned so much. In the beginning I felt confident going in and talking to my patients but not
caring for them. I was not confident about reading the EFM strips or even touching a patient in
active labor due to their pain. Even at the end I still was not comfortable dealing with patients in
extreme pain I think that's a learning
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The New Method Of The Creation Of Savior
Critics argue that permitting the creation of savior siblings through PGD is the first step down a
slippery slope that ends with frivolous reasons for selecting an embryo over another. The procedure
would open the door for parents to decide on specific characteristics of their babies. This is the
creation of fully–fledged 'designer babies'. As in the words of Josephine Quintavalle , "the new
technique is a dangerous first step towards allowing parents to use embryo testing to choose other
characteristics of the baby, such as eye color and sex". For this reason, the creation of savior sibling
is ethically impermissible since if one supports savior sibling, it is impossible to not support the
permissibility of designer babies. This argument ... Show more content on Helpwriting.net ...
Therefore, there is no reason why there cannot be a special process that allows selection for a certain
purpose and not others. It is distinctly different selecting for a specific HLA match to save the life of
a dying child and selecting for the color of a baby's eyes. One ought to accept that savior siblings
and other designer babies are morally different, and therefore, one can support the idea of a savior
sibling while rejecting the concept of a designer baby. In the case of the former, the prima facie
case– saving a life, as concluded by Sheldon and Wilkinson, for permitting savior siblings' selection
is much stronger than permitting designer babies because there is an important reason for the first
but not for the second (535). The value of a person's life is of much greater value the color of
another's eyes or hair or their height and weight. Therefore, the cases ought to be viewed differently,
"even if there is a slope there is no reason to believe that there will be a slide and there are important
differences between savior siblings and designer babies which the slippery slope argument
overlooks" (Sheldon and Wilkinson 535). At the same time, one cannot be naïve and fail to think
that there are real issues that are morally questionable lurking with the possibility of allowing savior
siblings. In the following section, I will look at the question of what
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Cord Blood Sampling
Introduction
Percutaneous umbilical cord blood sampling (cordocentesis) is a diagnostic test. In this procedure, a
small amount of blood (fetal blood sample) is taken from the umbilical cord and examined for
certain blood disorders and problems in the chromosomes of the unborn child (fetal chromosome
abnormalities). It is usually done after the 18th week of pregnancy.
This test may be used to diagnose these conditions in the unborn baby (fetus):
Infections, including those caused by:
A virus, such as rubella.
A parasite, such as toxoplasmosis.
Bacteria.
Birth defects.
Blood problems, such as anemia.
Bleeding disorders, such as:
Hemophilia A or B.
Von Willebrand disease.
Tell a health care provider about:
Any allergies you have.
All medicines you are taking, including ... Show more content on Helpwriting.net ...
This sample will be compared with the fetal blood sample.
You will be asked to lie down on an exam table.
An IV will be inserted into one of your veins.
You will be given one or more of the following:
Antibiotic medicine to help lower your risk of infection of the uterus.
A medicine to numb the area (local anesthetic). It is normal to have some cramping while the
procedure is being performed, even after getting this medicine. This is temporary.
An ultrasound will be done to determine the exact position of your baby.
A needle (syringe) will be inserted through the skin and into the umbilical cord to draw a small
amount of blood.
The needle will be removed.
The needle insertion site will be covered with a bandage (dressing).
The umbilical cord blood sample will be sent for testing.
The procedure may vary among health care providers and hospitals.
What happens after the procedure?
Your heath care provider will monitor you and your baby to make sure there are no problems before
you go home.
If your blood is Rh negative, you may need a Rho (D) immune globulin shot to help prevent
complications from the test. Ask your health care provider if you need to have this
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Nervous System
The Nervous System
The nervous system is the most complex part of the body, as they govern our thoughts, feelings, and
bodily functions. It is an important factor in science because it can lead to new discoveries for cures
or diseases. The studies of the nervous system helped lower death rates from heart disease, stroke,
accidents, etc. The nervous system is a network of neurons (nerve cells) that that sends information
to the brain to be analyzed. Neurons live both in and outside the central nervous system.
Understanding how the neurons work is vital to understanding the nervous system. Neurons The
neuron has two important structures called the dendrite and axon, also called nerve fibers. The
dendrites are like tentacles that sprout from ... Show more content on Helpwriting.net ...
Central Nervous System The brain and spinal cord forms the Central Nervous System. The spinal
cord gathers information from the neurons and sends it to the brain, but not all nerve impulses get
sent to the brain. Only a few impulses reach the brain, and an even smaller number reaches the part
of the brain where they cause awareness. The brain and spinal cord is made up of gray and white
matter, as well as the various nerve cells. The brain is divided into three parts: the forebrain,
midbrain, and hindbrain. The forebrain is called the cerebrum, the largest and most developed part
of the human brain. It is divided by the longitudinal sulcus, a deep crevice that separates the
forebrain into the left and right cerebral hemispheres. Each hemispheres control the motor
(movement) and sensory (sight, smell, hearing, taste, and touch) functions of the other side of the
body. The two hemispheres are divided into four lobes: the frontal, parietal, occipital, and temporal
lobe. The frontal lobe is involved with muscle control from head to toe. The parietal lobe obtains
sensory information from the skin and muscles. The occipital lobe receives information from vision,
and the temporal lobe controls speech. Although the four lobes do different jobs, they communicate
with each other to allow the brain to coordinate a response. The cerebrum combines the mixtures of
sight, sound, smell, and
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Selective Inos Inhibitor
Specific Aims
We propose to modify the recently discovered natural product terpenoids to develop a selective
iNOS inhibitor with improved in vivo properties.
Specific Aim #1: To confirm and enhance bonding of terpenoids to iNOS. A SILAC experiment will
allow the action of the small molecule on iNOS, eNOS, and nNOS to be confirmed. SAR studies
will then be performed to enhance selectivity towards iNOS and improve pharmacological
properties.
Specific Aim #2: To study the effects of iNOS inhibition on angiogenesis. The development of
vessels from human umbilical stem cells in the presence of either one of our terpenoids, a traditional
iNOS inhibitor, a genetic knockdown, or a control will be studied to determine the effect of iNOS
inhibition ... Show more content on Helpwriting.net ...
Provided the natural product does not simply quench nitric oxide, further testing will be performed.
Alternatively, if the natural product does show activity towards nitric oxide, it will be modified to a
moiety less sensitive to the radical before further testing is performed. To test for the selectivity of
these molecules SILAC testing will be performed. Using the computer dock data from the terpenoid
paper, a bead will be attached to the small molecule near the isopropyl group, which does not seem
to be involved in any major interactions in the active site. This bead placement will need to be
confirmed experimentally by testing the nitric oxide production of cells in the presence of the
compound and the compound with the bead are similar. After the location of bead placement is
determined, one set of cells will be grown with the small molecule in heavy medium and another
control set of cells in regular medium with no compound. After incubation, the proteins that have
attached to the small molecule can be determined through mass spectroscopy will be
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Embryonic Stem Cell Research Essay
Research on stem embryonic stem cells
We live in a world where genetic sciences have gone beyond laws, and past the imagination. We
have come to a point where we don't know anymore what is right, and what is wrong. We have to
decide. In fact, studies are made on embryonic stem cells that for now have the purpose to better our
overall health. These stem cells are extracted from extra IVF embryos; they are used and destroyed.
While it's true that this research could cure serious illnesses as Parkinson's, Alzheimer's, and orphan
diseases for example; however, it's also true that ending a potential life is immoral and illegal. We
could definitely find an alternative to the embryonic stem cells to develop the science. An embryo is
a life. ... Show more content on Helpwriting.net ...
No one gave us the right to take advantage on him and then kill him, and as noted in experiment–
resources.com: "humans should not be trying to play God". Fortunately, most of the leaders in the
world share this same opinion. During long years, governments of developed countries weren't
certain of what to do about this subject. They took different positions depending on the techniques
that were used: if the embryo was an extra IVF embryo or if it was created on that purpose; and on
the consequences the researches would have on him. Today, according to www.bionetonline.org ,
most of European countries such as France, Germany or Spain do not allow embryonic stem cell
researches. In United States, during Bush's administration, during 8 years, federal funding were not
given for embryonic stem cells researches. Indeed, in a letter to the House Members, NIH Director
Zerhouni said: "the president's position is still predicated on his belief that taxpayer funds should not
sanction or encourage further destruction of human embryos that have at least the potential for life".
Now, according to an article in About.com: U.S Liberal Politics titled: Pros& Cons of Embryonic
Stem Cell Research" President Obama have lifted the federal funding ban for embryonic stem cell
research". But still, laws are very clear, and even if using embryonic cells is allowed, credible
sources such as Wikipedia declare that "the creation of a human embryo
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Pros And Cons Of Cord Blood Banking
country are now recommending collecting the cord blood. "There's only two things that (you can)
potentially buy your new baby that are lifesaving: One is a good car seat and the other is cord
blood." Dr. Marra Francis, Ob/Gyn, CBR medical consultant gives his medical and personal opinion
of collecting cord blood.
Cord Blood banking also has it's limitations. Researchers have discovered that it is actually harder
for adults to be treated with cord blood than bone marrow. Children usually receive one unit of cord
blood because their small bodies only need a small amount. Adults however need more than the one
unit of blood that children receive because their bodies are so much bigger. According to
eurostemcells.org there are serious complications ... Show more content on Helpwriting.net ...
"Sick children whose parents did bank their blood sometimes cannot be used (Moniger, 67). Many
blood banks do not tell parents that if their children may develop a cancer or a disease early on in
their life that they may not be able to use the cord blood because the blood may be diseased. This
risk is one of the main risks that deter parents from paying the cost for banking. Another negative
aspect of cord blood collection and banking is that if a mother who delivers twins would like to
collect and store her children's cord blood, she would not be able to. Both babies may have a
different cord tissue type and they may be mixed during the collection process making them
virtually useless" (The Truth about Cord Blood Banking– Lucie's list, n.d.) . Also, If the mother ever
had cancer, she can not have her child's blood collected. This is because doctors do not want the
possibility of the cord blood to be contaminated with the cancer which in turn will contaminate the
patient receiving
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Essay on Stem Cell Research
Stem Cell Research
INTRODUCTION
A child is born everyday and without realizing it, the material that is routinely discarded after the
birth could one day be life saving for that person, someone else in the family, or even a complete
stranger. This material is the umbilical cord, and the blood contained within their vessels.
One may wonder, why is this blood so important? Medical research has discovered that the residual
umbilical cord blood contains stem cells. These cells are the building blocks that the body uses to
create some of the key components of the human immune system, blood and bone marrow. Stem
cells are essential for life, they carry oxygen, fight infections and platelets that form clots on injured
body parts. So if ... Show more content on Helpwriting.net ...
To date the procedure has been performed on a patient upwards of 230 pounds.
(http://www.caner.umn.edu/page/research/cord2.html). The blood is then cryogenically stored at –
385 degrees Fahrenheit in a private or public blood bank.
WHO BENEFITS Once the blood is collected, what happens to it? Parents choose whether they
want their child's blood reserved for "Directed donation" or "Public donation". With Directed
donation the blood collected from the newborn will only be used for treating a blood disease of a
sibling or immediate family member. It will be labeled and stored until it is needed. If a parent
chooses Public donation, their baby's cord blood will be donated to a general blood bank that anyone
might use.
SOCIAL AND ETHICAL QUESTIONS RAISED If parents choose a Directed donation, the blood
will remain in a private blood bank at an average cost of $1500, plus an annual storage fee of about
$100 (source: American college of Obstetrics and Gynecology). To some people, that may seem like
a small price to pay for all the potential benefits cord blood can provide, but what are the chances
that one of their children or a family member will ever need to use it? Many private cord banks
selling cord blood banking as a sort of "biological insurance" – just in case something happens.
Experts in blood banking and bone marrow transplantation frown upon this; they argue that people
are being frightened into
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Cord Blood Bank Essay
This Scientific Session will explore scientific and technical advances that forecast a dynamic future
for cord blood and cord tissue therapies. Presenters will discuss various models and tell how public
and family banks are positioning themselves within the medical field.
Since the first human cord blood transplant (UCBT) performed back in 1988, much has been learned
about UCBT. Cord blood banks have been established worldwide for the collection,
cryopreservation and distribution of UCB for HSCT. Today, a global network of cord blood banks
and transplant centres has been established with a large common inventory of more than 700 000
UCB units available, allowing for more than 40 000 UCBT worldwide in children and adults with
severe hematological ... Show more content on Helpwriting.net ...
In addition, innovative approaches using non–haematopoietic stem cells from cord blood and
placenta could be used for treatment of auto–immune diseases or for regenerative medicine.
Recently, the number of cord blood transplantation has declined because of the increased use of
unmanipulated cells of family haploidentical donors and the use of cyclophosphamide post–
transplant. Preliminary comparative results show, a similar early outcomes but the follow–up is still
too short to give recommendations for the choice between unrelated cord blood transplant or family
haploidentical mismatched transplant
Dr. Paramjit Dhot will give general overview of Cord Blood Banking and Transplantation.
Dr. Revathi Raj will explain the modalities of cord blood transplantation for various malignant and
non malignant hematological conditions in Apollo Hospital Chennai.
Dr. Joanne Kurtzberg (confirmation awaited) will discuss Cord Blood transplantation in
Neurological Disorders.
Dr. John Whener (confirmation awaited) will inform the audience about ex–vivo expansion of Cord
blood stem cells and discuss the future horizons in Cord Blood Banking and Cellular
... Get more on HelpWriting.net ...
The Ongoing Debate Over the Use of Stem Cells Essay
In the past two decades, many technological and scientific advances have been made in order to
make life easier for many people who suffer from cancer, disease and sickness. Among these
advances there is something revolutionary called stem cells. Stem cells can help restore and
regenerate almost all parts of the human body such as the heart, kidney, liver, and many other
organs. Although stem cells offer a lot, there are many views against and for stem cells, and among
these views lies the debate of whether stem cells should be legalized or not (NIH 2). Stem cells offer
exciting new opportunities in the field of science such as regenerating human body parts, but many
people are still debating whether or not the use of stem cells is ... Show more content on
Helpwriting.net ...
In order to get stem cells from embryos, the embryo must be destroyed, and many people view this
as killing a human, making it immoral. These embryonic cells can be given different tasks such as
making a specific organ, and this is how different body parts can be made. Stem cells have been
published in newspapers since 1998, but no institute or company invested money or time into stem
cells until 2001, when the Canadian Institute of Health Sciences decided to fund the research of
stem cells. Stem cells have three general properties, which are being capable of dividing and
renewing for long periods, they have to be unspecialized, and they have to be able to give rise to
specialized cells (NIH 3). Stem cells are unspecialized cells in embryos and umbilical cords that can
be modified using signals in order to make specialized cells which then have the ability form into
various different body parts such as livers, kidneys, hearts, and other major organs. The process of
when an unspecialized stem cell turns into a specialized stem cell is called differentiation (NIH 1).
In order for unspecialized stem cells to become specialized, one of the two types of signals should
be used. The first signal is called internal. Internal signals occur inside a cell by its own genes,
which are encoded on strands of DNA. The second signal is called external and this is possible with
external support such as chemicals, physical contact, or other molecules in the
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Tranformation of the Medical Industry Due to Advances in...
Over the years, medical industry has shaped and transformed due to the recent advance in
technology. It affects how we live and what we fear disease wise. With the incredible technology we
have now we've been able to gather more research about ourselves, like our DNA and cells. We've
been able to clone, create artificial organs, re–write our traits and even predict what we might have
in the cancer. We can also make designer drugs, and how much better the market for them can get
over time. With technology advancing every day of our lives soon we'd be able to create whole
humans with different functions born to do certain things, literally.
DNA is known as deoxyribonucleic acid. Deoxyribonucleic acid is a self–replicating material that is
known to be in almost every living organism. DNA is shaped like a twisted double helix and is
composed of long strands; sugars, phosphate groups as well as nitrogenous bases. This is organized
into structures called chromosomes and placed within the nucleus of our cells. DNA contains our
genetic information needed for the production of our other cells productions.
The history of genetic research began with Gregor Mendel or the "Father of Genetics". His study of
plants and reproduction brought interest to the study of genetics. Around the same time as Gregor
had conducted his studies, Friedrich Miescher discovered a substance called "nuclein", he isolated a
sample of what we know now as DNA. After his findings, his pupil, Richard Altman,
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Cord Blood
Cord blood refers to the blood that remains in the blood vessels of the placenta along with the
umbilical cord that it is attached to. Also known as placental blood or umbilical cord blood, cord
blood contains red blood cells, white blood cells, platelets and plasma. It is also rich in blood–
forming (hematopoietic) stem cells. These are similar to the ones found in bone marrow. Due to its
similarity with bone marrow, cord blood may be used for transplantation. Storing this blood can
potentially be used as a form of treatment for a child, should they become ill. The reason for this is
because, stem cells present in the blood can become any human cell. By storing this blood, it not
only helps the individual from whom the extra blood came from
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Cord Blood Research Papers
Trash to Treasure
The Pinterest world has changed the way we view trash. Things once tossed in the garbage now
hang on walls and adorn porches. Old milk cans, wooden pallets and chipped mason jars now have a
hundred new uses. These recycling trends that have been born this century don't end at making
living rooms more stylish, but extend to improving and saving lives. Technology is emerging to
harvest once discarded after birth and preserving it for research and treatment. Cord blood banking
is not only more ethical, but more efficient than its competitors and is therefore the future of stem
cell research.
Shortly after an egg is fertilized stem cells begin to form. These cells are programmed to form every
organ and tissue in the body as the baby develops. ... Show more content on Helpwriting.net ...
A limited amount of stem cells can be extracted from after birth, but these few cells can mean a
longer or improved life for someone (Bergman). In addition, people believe that harvesting cord
blood cells steals the cells from the child. The umbilical cord is cut and clamped just like a typical
delivery (CariCord). Delayed clamping, in which the cord is left attached to drain the blood back
into the baby, still allows the afterbirth to be donated. The science behind cord blood banking is still
developing because these treatments have only been performed for a little over ten years and the
only way to overcome that is to move forward with research (Stem Cell). Cord blood cells hold the
potential of becoming brain and heart cells and combatting serious neurological diseases. The
science is young, but one out of every three hundred kids are plagued with cerebral palsy and one of
every sixty–eight children battle autism (What It Is). The chance of helping people throughout the
world live a better life fuels the need for an increase of support in this budding
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Umbilical Cord Blood
There are so many people in this world today that are diagnosed with blood disorders, and other
cancerous diseases. Along these terrible diseases comes a long, painful journey of treatments, like
bone marrow transplants. But, bone marrow transplants aren't the only transplants in this world now.
"In the outstanding findings of 1980 an estimation of more than 130 million infants are born, and
umbilical cord blood (UCB) is known to be the most abundant reservoir of hematopoietic cells for
many clinical applications." (Waller–Wise R.)
Umbilical cord blood has many potential usages, yet mothers don't know about it. Instead of using
the umbilical cord blood, doctors usually just dispose of it. What mothers don't have the knowledge
of is that ... Show more content on Helpwriting.net ...
This is because one unit of umbilical cord blood won't affect adults whatsoever. There aren't enough
hematopoietic stem cells in one unit. This is why scientists and clinical trials are doing their best to
come up with a way to double the unit so adults are able to use it, and not just adolescence.
Scientists are also still studying more ways to treat diseases with cord blood. At Duke University, for
example, researchers are using patients' own cord blood in trials for cerebral palsy and Hypoxic
ischemic encephalopathy (a condition in which the brain does not receive enough oxygen). Trials
are also under way for the treatment of autism at the Sutter Neuroscience Institute in Sacramento,
California. Also, according to the New England Journal of Medicine, cord blood is still better than
marrow transplantations after studies were done. The adult patients in the trial had advanced
leukemia, and were then give a bone marrow transplant, but recovery was slower because they
weren't matched. On the other hand, the leukemia patients that were given cord blood transplants
had more matches than bone marrow, and also had no acute graft–versus–host disease. "A really
exciting area that's just now in the basic science lab, is the area where stem cells...can be used for
going over to muscle cells like your heart muscle if you had a heart attack...or brain cells if
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Stem Cells And Regenerative Medicine : Cord Blood Banking...
Name: Darshana Chaudhary
Student Number: s5024975
Course: 7001HSV Applied Research Methods
Tutor: Jennifer Boddy
Due Date: 14th September 2015
Date Submitted: 14th September 2015
Word Count: 1671 words
STEM CELLS AND REGENERATIVE MEDICINE : CORD BLOOD BANKING AND ITS
THERAPEUTIC APPLICATION
Abstract :
Stem cells can give rise to any tissue found in the body and thus provide nearly limitless potential
for medical applications . Stem cells have the great potential to develop into many different cell
types in the body during early life and growth. They serve as a repair system . Due to unlimited
therapeutic applications of stem cells , they continue to be of great importance scientifically and ...
Show more content on Helpwriting.net ...
Human embryonic stem cells . Patient–specific therapy.
METHOD :
Articles for this review were selected from Pubmed Central and Medline databases and proquest
databases.
Introduction :
Stem cells are able to generate mature terminally differentiated cells of atleast one lineage and
possess the capacity of self–renewal .Stem cells can be categorized as totipotent, pluripotent or
multipotent according to their developmental potential. (Takahashi and Yamanaka 2007).
Stem Cell Classification Based on Differentiation Potential:
Stem cells can be classified based on their ability to differentiate. They are classified into following
five types :
Totipotent Cells: Totipotent cells are found in early stage of development .The totipotent cells forms
the embryo and the placenta and differentiate into both embryonic and extraembryonic tissues.
Pluripotent Cells: Pluripotent cells differentiate into cells that arise from three germ layers called –
ectoderm , endoderm and mesoderm , from which other tissues and organs develop.
Oligopotent Cells: oligopotent are capable of self renewal and differente into many tissue types.
Unipotent Cells: unipotent cells are capable of self renewal and differentiate into only one single
type of cell.
Multipotent Cells: They are found in most tissues and differentiate into cells from a single germ
layer. (Kolios, 2012) Sources of Stem Cells for Regenerative Medicine:
There are a number of cardiovascular , neurological
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How Henrietta 's Cells Were Recovered, And Stored
I begin writing this essay about Henrietta Lacks by discussing option number three outlined in this
project. Before this class had begun, I could not tell you how or why such vaccines came to be. I can
almost relate to the author in the beginning of the book when she is in her college biology course
and has no idea who Henrietta Lacks is. This book outlines so many big topic issues, and I feel they
all play a role in how Henrietta 's cells were recovered, and stored. From my own personal
viewpoint, I feel one of the biggest issues for myself personally, is the bioethics of it all. Working in
healthcare and living in this generation, money, is a monumental factor that defines just about
everything. "Money, defines how we test drugs, why ... Show more content on Helpwriting.net ...
Would she have still if it would not profit her, or her family, but so many others around the world
who are sick? Another factor that played a significant role in Henrietta 's life was a combination of
not only poverty, but racism too. The book calls into question the name Henrietta Lacks. "We are
officially introduced to Henrietta as Loretta Pleasant. Henrietta, or also known as Loretta, grew up
with eight other siblings, and an abusive father." (Biogrophy.com) Henrietta spent most of her youth
living with her grandfather and future husband. During this time in history, Henrietta along with
other African Americans, were subjected to segregation. Her life was far from easy, she grew up as
many African American children did during those times, working in the tobacco fields. It seems to
me that this woman had a tremendously hard life. She endured: her mother 's death, being divided
from her family, segregation, child labor working in the tobacco fields, a philandering husband, and
cancer to name just a few things. I honestly cannot begin to imagine this lifestyle much less cancer.
What stands out to me about her is that I portray her to be this strong, resilient woman. I say this
because she refuses treatment for her STDs, goes on sleeping with her husband bearing him children
, and most of all, she was a God fearing woman. I can only begin to imagine during this time in
history being a woman, much less an African American woman, had its struggles and
... Get more on HelpWriting.net ...
Persuasive Essay On Donating Children
Having a child can be one of the most exciting experiences for a parent. However, bringing a child
into the world can also be a very scary experience. Every parent's wish is to have a healthy baby, but
sadly this is not always a reality. When a child is born with a disease the whole dynamic of a family
changes, doctor visits and medication become the new norm. Sometimes families are even faced
with the difficult decision of life or death for their child, which can only be cured by using donations
from a close match. Depending on the person, the likelihood of finding your perfect match from the
donor list can be slim. With that having been said, many parents turn to the decision of conceiving
another child to be the donor for their already living ... Show more content on Helpwriting.net ...
There are many people who are opposed to conceiving a child to be used as a donor, so it is
important we acknowledge their oppositions. There are three main points against the conception of
children for the use of stem cell donations. The first is explained by Elaine R. Morgan, from an
article titled Having a child to save a sibling, "the emotional endangerment of the child because of
the motivation for its conception." (Morgan, ET.AL, 1). Morgan brings up a very valid point, often–
times the child who is donating begins donations from birth. As a very young donor, the child may
not fully understand the procedures. It is also a very heavy concept to weigh on a child, that their
sibling could die without their help. Jennifer P. D'Auria adds to Morgans findings on emotional
endangerment of a child, in an article titled Through the eyes of young sibling donors, she described
children remembering "immense pressure and emotions they felt to be that perfect match". Although
it can be extremely taxing on a child to have life or death weighing on them, D'Auria assessed 44
children and majority felt there was no question in whether or not they wanted to step up to save
their sibling, "To me there was no choice. It was you can either have a brother or you cannot have a
brother. That was my choice". Morgan and D'Auria can both agree that there are emotional risks
when going through a procedure like this, there is no guarantee that it will work so if it didn't the
child may certainly be emotionally unstable. But what D'Auria explains through the research with
many patients, is that the child willingly wants to help their sibling, they would do anything for
them. Every medical procedure has risks and as medical technology continues to advance, the risk
of procedures has been decreasing. When Morgan claims that children
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A Research Study On Umbilical Cord Blood
Umbilical cord blood (UCB) contains a substantial number of stem cells that have the potential to be
used in various transplants to treat a variety of immunodeficiency, oncologic, hematologic and/or
genetic disorders. UCB is found most commonly in the blood of newborn babies. Once the baby is
born, the blood that remains (that was previously thrown away as 'medical waste') in the umbilical
cord and placenta can be taken and stored, to be used later for transplantation or research (Pandey,
Kaur & Kamath, 2016). Recent studies in the last decade have shown that UCB is a great source of
stem cells, which makes it a valuable resource in the field of stem cell therapy. Stem cells have
amazing potential for therapeutic use in tissue repair and regeneration.
In October 1988, the first umbilical cord blood transplant was done on a young five–year old boy
named Matthew Farrow in France, who was diagnosed with severe aplastic anemia due to Fanconi
anemia. The umbilical cord blood was collected at birth from Matthew's newborn sister who,
through prenatal testing, had been found to be unaffected by Fanconi anemia and was HLA–
identical to Matthew. The UCB was cryopreserved and taken from Indiana to France, where it was
then thawed and injected into Matthew. There was no evidence of graft–versus–host disease, and
according to Ballen, Gluckman and Broxmeyer, as of 2013, Matthew is "healthy with complete
long–term hematological and immunological donor reconstitution 25 years after
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The Ethical Dilemma Of Hepatitis Sachs Disease
Often times in a complex situation individuals are involved in conflicting decisions to progress to a
solution. The ethical dilemma may conflict with acceptable morals or behaviors but to resolve the
paradox a decision has to be made. D.B.'s parents are faced with an ethical dilemma when they
discover their son has an incurable disease. They could allow the illness to take its course or seek a
form of treatment to slow its progression.
Ethical Dilemma
D.B. was born May 30, 1999, with a condition most commonly known throughout the Eastern
European Jewish community. Tay–Sachs disease is a condition caused by a lack of hexosaminidase
A (Hex A) enzyme in the brain used to breakdown gangliosidosis (GM2) enzymes or the brain
begins to swell, ... Show more content on Helpwriting.net ...
would recover and have a chance to survive the disease. The parents made a decision for their son in
hopes the odds would be in his favor.
ANA Code of Ethics
Provision two, four, and six are a few ethical principles relevant and applicable to the situation. The
healthcare team respected the clients wishes, committed to the client's health, took accountability for
care and practice, and contributed to the healthcare environment. Provision Two: Primary
commitment is to the patient, whether an individual, family, group, community, or population.
Provision Four: Authority, accountability, and responsibility for nursing practice; makes decisions;
and takes action consistent with the obligation to promote health and to provide optimal care.
Provision Six: Through individual and collective effort, establishes, maintains, and improves the
ethical environment of the work setting and condition of the employment that are conductive to safe,
quality healthcare. (Hegge, 2015).
Relation of the ANA Code to the Dilemma
American Nurse Association Code of Ethics principles relates to the care provided for the client
while under supervision of the healthcare team during their dilemma. The healthcare team
establishes principles to abide by in order to provide optimal, safe, efficient care for their clients.
The team successfully met the goals of the fourth provision by "making decisions and taking action
consistent with the obligation to promote health
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Cord Blood Case Study
Did you know that cord blood can treat over 80 medical conditions and diseases?
Cord blood refers to residual blood that's present in the placenta and umbilical cord immediately
after a baby is born. This blood can be gathered and stored to treat various types of illnesses and
medical conditions.
When harvested immediately after the birth of a baby, cord blood has a number of stem cells that
can take the form of other cell types in the body such as fat, liver, muscle, nerve, and blood cells.
Here are five types of medical conditions the harvested blood can treat.
1. Cancers
A number of cancer types, among them leukemia and lymphoma, can be treated with cord blood.
Cancer, which can decimate a patient, is characterized by constant pain, weight ... Show more
content on Helpwriting.net ...
These disorders occur as a result of cellular structure imbalances in the body and can cause blood
clots, swelling, and excessive bleeding.
Specifically, cord blood can be used to treat a variety of blood diseases such as congenital
amegakaryocytic thrombocytopenia, amyloidosis, essential thrombocythemia, pure red cell aplasia,
and many others.
3. Metabolic Disorders
Cord blood can be used to treat metabolic disorders such as krabbe disease and hurler syndrome,
which have been known to cause weight loss, seizures, and frequent body pain. These medical
conditions can be life–threatening. Cord blood can be used as a treatment option for patients with
other metabolic disorders as well, such as sly syndrome, tay sachs, niemann–pick disease, and
lesch–nyhan syndrome, among many other conditions.
4. Immune Disorders
Cord blood can also be used to treat immune disorders such as myelokathexis and evans syndrome
that cause the body to attack itself. The resulting frequent fevers and fatigue can be very debilitating.
In some cases, immune disorders can be fatal. Among immune disorders that can be treated with
cord blood include severe combined immunodeficiency diseases, hemophagocytic
lymphohistiocytosis, and many other medical
... Get more on HelpWriting.net ...
Stem Cell Research: The Benefits of Stem Cells Essay
In Brazil 2009, there was an 18 year old boy that had half of his jaw and teeth removed because of a
tumor. Scientists took some of his bone marrow and extracted the adult stem cells from it and
formed an osteoblast, which is a bone forming cell. Six months after the osteoblast was injected, it
started forming new bone material which filled the gaps (NIH Stem Cells). Stem cells could be a
genius way to treat many diseases and disorders and it should be supported by everyone.
Stem cells get their name from the fact that they are basic cells that other cells develop from. They
are capable of developing into a wide range of cells. Stem cells could potentially be used to grow
new cells to replace the cells that were destroyed or damaged by ... Show more content on
Helpwriting.net ...
Scientists need to know that all the stem cells completely change into the tissue to avoid negative
side effects, like tumors, when the cells are implanted in patients. Scientists also try to
experimentally treat diseases with no cure with stem cells by implanting them into animal models,
like mice (Freedman 13). Many different groups of people protest stem cell research. Some
protesters say that getting stem cells from embryos amounts to killing a person to improve the life of
another (Freedman 18). People protest stem cell research even though the embryos and fetuses
would be discarded anyway (Freedman 19). They think if it is accepted, they will start
experimenting on people who are going to die, like death row inmates and terminally ill people
(Freedman 22). Some supporters of stem cell research say that using tissue from dead embryos is
equivalent to transplanting organs from people that died from homicide or suicide. They say stem
cell experiments in animals have already shown improvements in disorders. Treatments for diseases
and disorders can't be developed if experiments aren't performed. There are a lot of potential uses of
stem cells, but there are obstacles that we need to go through first. Stem cells can be used to test new
drugs that scientists make. We could generate healthy heart muscle cells with stem cells. Injected
cells could repair things in the body by secreting growth factors. Before scientists start
... Get more on HelpWriting.net ...
Symptoms And Symptoms Of Krabbe 's Disease
Krabbe's disease has many signs and symptoms. There are three stages of this condition in infantile
form. Stage 1: The infant is seemingly normal and healthy for the first couple months after birth.
However during early onset of this disease, the child has signs of incoordination, vomiting,
irritability, unexplained fevers and stiff posture. Initial symptoms that may occur are seizures
(Wenger 2000). There is slight developmental regression and behavioral abnormalities, in particular,
displaying hypersensitivity to sound and touch (ORDR). Throughout this stage, the Cerebrspinal
Fluid (CSF) protein concentration at this point is significantly increased (Wenger 2000). The CSF is
a liquid that bathes the brain and spinal cord. Its function is to cushion the brain and spinal cord,
protecting against injury. It also circulates chemicals and certain nutrients that are filtered from the
blood and it also removes waste products from the brain (Lantos 2011).
The second stage of Krabbe's disease involves aplasia and hypoplasia, which is a defective
development of the abdominal wall musculature. There is also hypertonia, which is damage to the
Central Nervous System (CNS). The CNS is the brain and the spinal cord, which controls most of
the functions of the body and mind. There is also visual impairment, sensorineural hearing loss
(SNHL), cognitive impairment, and electromyography (EMG) abnormalities (ORDR). These
symptoms vary from person to person (Wenger 2000). Some less common
... Get more on HelpWriting.net ...

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Cord Blood Banking Pros

  • 1. Cord Blood Banking Pros When making any decision regarding a child's future, any parent would (presumably) opt for a choice that increases the child's chances for health and well being. In recent years parents have been offered the option to save umbilical cord blood. This procedure has become known as cord blood banking. Cord blood banking has been discovered to offer many ways to help ensure not only the child's health, but in some cases, other members of the family as well. Cord blood banking offers a plethora of health benefits that can save a child and their family from suffering the devastating effects of many diseases. Cord blood could, in many cases, essentially save your child's life. So what is cord blood banking? Cord blood banking is the process of storing the stem cell–rich blood from the umbilical cord after a mother gives birth. The stem cells are the key that unlock potential for treatment for conditions such as brain and spinal cord injury, some types of cancer, including leukemia, brain and heart tissue repair, and many others (2015). One of the reasons that there is such a positive success rate when using cord blood for these medical conditions is that for the child, the stem cells are a 100% match. (GET MORE DATA REGARDING WHY THE BLOOD IS ... Show more content on Helpwriting.net ... Firstly, the child's stem cell–rich blood is stored indefinitely, and available when/if the child or other family member may benefit from its use. Instead of a donor having to undergo painful bone marrow transplants, with a chance of it not being successful, cord blood can be used. As mentioned, since it would be a 100% match to the child, there would be very little likeliness of his/her body rejecting the transplant. In some instances, the cord blood could be used to treat a sibling or other family member (depending on the condition). Lastly, the peace of mind derived from knowing that you have taken a viable, (REWORD) to ensure your child's future health and ... Get more on HelpWriting.net ...
  • 2.
  • 3. The Treatment Of Stem Cell Therapy Stem cell therapy, also known as regenerative medication, has been an increasingly utilized therapy in recent years. The cells added to the body interact with the surrounding body, making the regenerative process available to begin the healing process of the cells at the site (R. (2014)). These therapies are used to heal common sport injuries such as a knee injury, diseases, arthritis, and many other crippling effects that may occur in the human body (R. (2014)). Many of the stem cells that are used from the therapies can come from bone marrow, fat,and blood from the patient or even cells from more controversial areas such human embryos. Stem cell therapy has shown a lot of promising effects, not only outshining the effects of prescription medicine given out to patients from doctors, but it has also shown that the therapy has long term effects than a steroid would have had. Stem cell therapy is important because it has given hope to several people with common illnesses such as arthritis, knee pains, and back pains by regenerating their cells to realize the pain that they are in. Most of the patients who come in for sport related injuries are professional athletes.Most of the time these athletes are the ones who have obtained a knee injury in basketball or football and are resorting the use of a steroid to try to fix the pain, but soon realize that it is not a long–lasting effect. This is where stem cell therapy comes into play. Chris Johnson from the New York Jets was one ... Get more on HelpWriting.net ...
  • 4.
  • 5. Focal Nervous System Paper The general structure of the nervous system is known as the "anatomy of the nervous system" (neuroanatomy). The acts of human beings are guided by controls through the nervous system. A human being's response to its environment is also through controlled guiding and thoughts (Pinel, 2013). The peripheral nervous system or PNS and central nervous system or CNS are important parts of our nervous systems within hollow tube holding the CNS and PNS of our nervous system (Pinel, 2013). There are subdivisions of these two sensory systems that have structure and capacities. Focal Nervous System: AS the name recommends, it is focal and the two primary segments of the focal sensory system are mind and spinal rope, which are under the assurance of exceptional ... Get more on HelpWriting.net ...
  • 6.
  • 7. Stem Cell Type Is Best? Topic: Stem research, which stem cell type is best? Umbilical cord stem cells or embryonic stem cells. General Purpose: To inform Specific Purpose: To inform the audience of the advantages and disadvantage of using embryonic and umbilical cord stem cells in research. Central Ideal: While medical researchers believe that the use of embryonic stem cells is their best option in research, others believe it to be unethical and immoral, and that umbilical stem cells are a good alternative to embryonic stem cells. Organizational pattern: Topical I. Introduction: A. Attention Getter: Some believe that murder is committed each day in the name of science. B. Reveal Topic: While medical researchers believe that the use of embryonic stem cells is their best option in research, others believe it to be unethical and immoral that umbilical stem cells are a good alternative to embryonic stem cells. C. Audience Motivation: Every person will be or has been touched by cancer, diabetes, arthritis, Alzheimer's or some other devastating disease during their life time. Would you support any means of research to find a cure that may end human suffering even if it meant death of a human? D. Qualifications/Credibility: After must reading and research of the stem cell issue, I am qualified to speak about the pros and cons of using embryonic stem cells and umbilical (adult) cord stem cells. E. Purpose and Preview: I am here to present the pros and cons of embryonic stem cells verses umbilical ... Get more on HelpWriting.net ...
  • 8.
  • 9. The Ultimate Life Insurace Policy--Cord Blood Essay Over the last several decades, the field of medical technology and research has become increasingly advanced. Just read up on any of the most recent innovations; what may have once been considered science fiction is rapidly becoming reality. Some of the most publicized scientific discoveries are related to stem cells, as the controversial research and use of certain types of these cells is continuously being debated among politicians, scientists, and religious leaders. However, it is believed that a specific type of stem cell, an umbilical cord blood stem cell, may be used to treat a number of diseases, disorders, or injuries devoid of ethical controversy. Banks for storing cord blood exist in countries all over the world and its use is ... Show more content on Helpwriting.net ... The first type of stem cell, an embryonic stem cell, is known for being able to continuously multiply, as well as for being pluripotent. They can be "derived in vitro from the blastocyst of an embryo usually left over from in vitro fertilization" (Forraz & McGuckin, 2011, p.61). Unlike other types of stem cells, embryonic stem cells have yet to be used in any kind of clinical treatment of patients. The high risks of "immune rejection" or "teratoma formation" are serious obstacles (Harris, 2009, p.182). The second type of stem cell, adult stem cells, is primarily considered to be multipotent and may be found in "specific adult human tissues" such as the skin or bone marrow, just to name a few. Over the last twenty years, the amount of scientific research and trials using adult stem cells has grown significantly, despite their lower potency than embryonic stem cells (Forraz & McGuckin, 2011, p.61). Lastly, cord blood stem cells, are technically considered to be a special type of adult stem cell, but their youthful properties give them "greater restorative and regenerative potential." Directly following the birth of a child, these stem cells can be collected from the blood in the umbilical cord (Steenblock & Payne, 2006, p.9). Embryonic, adult, and cord blood stem cells ... Get more on HelpWriting.net ...
  • 10.
  • 11. Brain Disorders: What Is Cerebral Palsy? What is Cerebral Palsy? Cerebral palsy is a general term for a variety of disorders caused by damage to the brain. The damage occurs before or during birth or in the first few years of life. The brain damage may cause severe crippling, or the symptoms may be so mild that they hardly interfere with the patient's activities. There are several types of cerebral palsy, and all involve lack of muscle control. Common effects of the disorder include a clumsy walk, lack of balance, shaking, jerky movements, and unclear speech. In many patients, the brain damage also causes intellectual disability, learning disability, seizures, and problems in sight and hearing. About half of 1 percent of the people in the world have cerebral palsy. What are the causes? In most cases, the causes of faulty growth of the brain that result in cerebral palsy cannot be determined. In some cases, however, brain damage may result from illness in the mother during pregnancy. For example, rubella can severely harm an unborn child, even though the mother may have had only mild symptoms or none at all during pregnancy. Cerebral palsy is rarely an inherited trait. Brain damage can also occur during the birth process, especially in premature births. In babies born after a normal term of pregnancy, brain damage may ... Show more content on Helpwriting.net ... These types are (1) ataxic, (2) athetoid, (3) hypotonic, and (4) spastic. In the ataxic form, the patient's voluntary movements are jerky, and a loss of balance is suffered. In the athetoid type, the person's muscles move continually. These movements prevent or interfere greatly with voluntary actions. A person with hypotonic cerebral palsy appears limp. The person can move little or not at all because the muscles cannot contract. Spastic cerebral palsy patients have stiff muscles and cannot move some body parts. A person with cerebral palsy may have more than one muscle disorder. The person may be only slightly disabled or completely ... Get more on HelpWriting.net ...
  • 12.
  • 13. Making Positive Changes For Expectant Parents Within this essay, I will reflect on an event that I witnessed during clinical placement, focussing on the process of non–directed donation (RCOG, 2006) of umbilical cord blood via the onsite NHS Blood and Transport (NHSBT) team, as well as the related issue with the antenatal communication and subsequent consent to utilise the service. In order to maintain confidentiality in accordance with the Nursing and Midwifery Council's Code of Conduct (NMC, 2008) and The Data Protection Act (1998), the hospital and the people involved in the event, (as well as those involved in subsequent conversations as a result) will not be referred to by name. I have used the Gibbs reflective cycle (Gibbs, 1988), and will be relating the event back to recent research and relevant hospital and governmental procedures wherever possible. As a result of this assignment, I have undertaken further research that will be outlined below, which I hope will assist in making positive changes for expectant parents in the future. Donation of umbilical cord blood is a trend that has grown in popularity in recent years, and is now offered on site at several NHS trust hospitals (RCOG, 2006). Despite this service being readily available to expectant parents within my placement hospital, it became clear during my second week that the relevant information regarding donation was not being provided soon enough in the antenatal period which would allow for an informed decision to be made as to whether or not ... Get more on HelpWriting.net ...
  • 14.
  • 15. Autonomic Dysreflexia Research Paper What is Hyperreflexia? Hyperreflexia, also known as autonomic dysreflexia, is a state that is unique to patients after spinal cord injury at a T–5 level and above. Patients with spinal cord injuries at Thoracic 5 (T–5) level and above are very susceptible. Also patients at Thoracic 6 – Thoracic 10 (T6–T10) may be susceptible. Patients with Thoracic 10 (T–10) and below are usually not susceptible. Also, the older the injury the less likely the person will experience autonomic dysreflexia. Hyperreflxia can develop suddenly, and is a possible emergency situation. If not treated promptly and correctly, it may lead to seizures, stroke, and even death Autonomic dysreflexia means an over– activity of the Autonomic Nervous System. It can occur ... Show more content on Helpwriting.net ... Perform a digital stimulation and empty your bowel. If you are performing a digital stimulation when the symptoms first appear, stop the procedure and resume after the symptoms subside. If your bladder or bowel are not the cause, check to see if:  You have a pressure sore  You have an ingrown toenail  You have a fractured bone If you are unable to find the stimulus causing autonomic dysreflexia, or your attempts to receive the stimulus fail, you need to obtain emergency medical treatment. Since not all physicians are familiar with autonomic dysreflexia (hyperreflexia) and its treatment, you should carry a card in your billfold that describes the condition and the treatment required. How can you prevent Hyperreflexia? Prevention of autonomic dysreflexia is very important. Following are precautions you can take which may prevent episodes: If you have an indwelling catheter:  Keep the tubing free of kinks  Keep the drainage bags empty  Check daily for grits (deposits) inside of the catheter. If you are on an intermittent catheterization program, catheterize yourself as often as necessary to prevent ... Get more on HelpWriting.net ...
  • 16.
  • 17. Spinal Cord Injury Research Paper vThe spinal cord is well–protected anatomically with barriers, vertebra, muscles of the back, and the meninges. A considerable force is required to cause trauma to the neural tissue of the spinal cord. This can be laceration or maceration by a sharp penetrating object; contusion or compression, the most common form of spinal cord injury; or infarct by vascular insult. All of these injury forces begin the process of tissue destruction we term the primary injury. These mechanical forces predominately damage the central grey matter, due to its softer and highly vascularised nature, causing massive loss of essential cells, including local neurons, astrocytes, oligodendrocytes and endothelial cells in the vicinity of the injury site (Dumont et ... Show more content on Helpwriting.net ... This protein has been shown to activate the epidermal growth factor receptor (EGFR) thereby inhibiting neurite outgrowth and axon regeneration (Schachtrup et al., 2007). In addition to plasma proteins, there is invasion of blood circulating inflammatory cells into the spinal cord through the disrupted BSB. Since spinal cord is considered as an immune–privileged or immunologically quiescent site, the sudden influx of immune cells dramatically alters the regulation of the inflammatory response in the injured spinal cord (Trivedi et al., 2006). This dysregulation of the inflammatory response plays a major role in enlargement of tissue damage in the secondary phase of the injury. As such, it is thought that the initial damage to the local blood vessels and BBB is decisive for the disruption events that cause the secondary phase of injury (Mautes et al., 2000a, Mautes et al., ... Get more on HelpWriting.net ...
  • 18.
  • 19. Umbilical Cord Blood Harvesting I. Introduction A. Attention getting opener: There is a critical need for effective, long–term solutions for harvesting stem cells. Already there are "more than 300,000 units stored worldwide. These products have been banked under stringent quality conditions, in order to ensure their safety and efficacy," (Vladareanu, Mihailescu & Zvanca, 20070, p. 142). B. Credibility statement: Abundant research shows that harvesting stem cells from umbilical cord blood offers crucial advantages over other methods, including bone marrow and peripheral blood. C. Thesis: Although not an ideal medium for harvesting, and will not replace other types of stem cell sources, umbilical cord blood should be an integral part of the blood/tissue bank repertoire. II. Advantages of using umbilical cord blood. A. Immunology 1. "Umbilical cord blood (UCB) contains stem and progenitor cells capable of restoring haematopoietic and immunological function in vivo," (Navarette & Contreras, 2009, p. 236). 2. Umbilical cord blood stem cells "can be transplanted to regenerate a patient's immune system," (Vladareanu, Mihailescu & Zvanca, 20070, p. 142). B. Pre–frozen/cryopreservation 1. cryopreservation allows for the storage of stem cells for future use, eliminating need for searching for suitable donor 2. Especially true when minorities need transplants (Samuel, et. Al, 2007). C. Advantages over other forms of stem cell 1. Bone marrow cell harvesting "may be detrimental due to the ... Get more on HelpWriting.net ...
  • 20.
  • 21. Essay Legalize Stem Cell Research Stem cell research should be legal and funded by the government in all 50 states. There are several types of stem cells that we have available to use for research. The controversy comes from the use of Embryonic Stem Cells (ESC) and how they are obtained. The funding is very unstable for stem cell research due to the use of ESC, combined with the message they send. There have been several arguments in regards to the right to life. In–Vitro Fertilization (IVF) clinics have never been funded by the government and that is not the plan for this research either. Even if the research was funded by the government, the stem cells would continue to live on. Stem cells are used to find cures for life threatening diseases. Research of stem cells is ... Show more content on Helpwriting.net ... Somatic Stem Cells show they are resourceful and have been in use for a very long period of time, Somatic Stem Cells can help cure disease. Without continued funding for this, researchers would be unable to find other cures, like the already in process bone marrow transplants. The rejection rate theory is very powerful, being able to save lives with low complications; however, if the research is not funded, we might not be able to stop the person from getting the illness again, considering the illness is most likely in the genetic makeup of the individual. Three is a need for continued funding for this research, at least until researchers have exhausted all avenues, finding every possible capability of these Somatic Stem Cells. The second type of stem cell in use is the Umbilical Cord Blood Stem Cells. These stem cells come from the umbilical cord of a newborn which generally would get discarded. Otherwise, these cords are frozen and stored in a private blood bank, in case the stem cells should ever be needed by the donor or their family ("Umbilical Cord Blood", par. 23). The processes to save these cells is; something like this, the parents pay a onetime fee and they receive a package for sending the cord in after delivery, after the initial process the family pays an annual storage fee to continue to ... Get more on HelpWriting.net ...
  • 22.
  • 23. Questions On Private Practice Dilemma: In the season 2 premier of Private Practice, we are introduced to a couple that have a sick son who was dying of Acute Lymphoblastic Leukemia. They had a partial match donor to help save the son life but unfortunately the partial match donor was found to have pneumonia. Because the doctors thought the son had a donor they started to prepare him for the transplant by stripping his immune system and unless he received the transplant within a week he would die. The parents had already become pregnant with a genetic match to their son, so that they could use the baby's umbilical cord blood in the future. The wife was 27 weeks pregnant when she and her husband request that Doctor Addison induce her delivery to preform a C–section this ... Show more content on Helpwriting.net ... If doctor Addison does this she can control how the C–section will work and she can have different teams ready, one team to help with the umbilical cord transplant for the son, another team ready to care for the premature baby, and one team to help the mother and finish the C–section. This would allow for the son to receive the transplant, saving his life. But the premature baby must be carefully cared since the chance of dying is high, she would need to be monitored and forced to stay in the hospital for quite some time till fully development or approval from doctors. Perspective number 2: Another perspective for this case is that Doctor Addison does not preform the C–section. The sick son would be placed back on the transplant list with the hope that they could find another donor before the son dies. But most likely the son would die since he only had a week left to live. Although, this wouldn't place the unborn baby at risk for complications due to being born premature. The women was 6 months pregnant and the doctors were not concern of any risk, only increasing the likeness of the couple having a healthy baby being born. Perspective number 3: Another possible perspective is for the mother carrying the baby to endure her own delivery such as by breaking her own water. This puts the mother at risk because she has to induce her own delivery without the knowledge of the proper way to ... Get more on HelpWriting.net ...
  • 24.
  • 25. Cord Blood Banking Essay 1. What is an umbilical cord blood banking and what role it plays in a stem cell research? Over the past two decades, the stem cells became an important part of a medical research. Today, stem cells are used to assist in treating numerous diseases. The umbilical cord blood can now be saved in special banks to preserve the youngest stem cells for an unlikely event the child later develops a certain kind of illness. Although there has been a lot of talk about research using stem cells, most people don't come in contact with the topic of cord blood banking. This issue is exclusively presented to expecting parents. I want to use this question to inform unfamiliar readers about cord blood banking and its use in stem cells research. I intend to use this a question as an introduction to this topic in my research essays. 2. How can the latest research in stem cells used from cord blood and tissue banking support expectant parents' decision to save their baby umbilical cord blood? This could also be a main topic question. This question can furthermore investigate my first question on ... Show more content on Helpwriting.net ... They can also see the cord blood banks frequent advertisings in many expecting parents' magazines. Unless the expecting parents do more research, very few learn about public cord blood banks. There are advantages and disadvantages associated with each option. For example, the cost of a private cord blood banking is still very high, but the cord blood stays availably exclusively to the client. The public cord blood banks collect a cord blood by donation. Unfortunately, this option is not available in every hospital and the donated cord blood may not be accessible by the original donor if needed. This question is worth exploring further, and it also compliments the other two questions on this ... Get more on HelpWriting.net ...
  • 26.
  • 27. Biol101 Homework Assignment 2 Essay B) Stem cells. A relative of a friend of yours had a spinal cord injury after a bad car accident. The medical team has decided that this patient is a good candidate for a clinical trial using stem cell therapy. Your friend has not had a biology course since high school, so you are going to write for him or her a two–page discussion of stem cell information. In your discussion, include a description of the biology of stem cells, and explain how these cells are unique in their ability to treat diseases and injury. The following website from NIH regarding stem cell research will be very helpful: http://stemcells.nih.gov/index.asp. Before we determine how stem cells can treat various diseases including spinal cord injuries, let us first ... Show more content on Helpwriting.net ... Many wonder why the spinal cord is not able to heal itself like the other parts of the body such as how the skin injured on a leg can regenerate and heal itself or how muscle can repairs itself is it gets strained. But the spinal cord is different. That is because some of the cells in the central nervous system are so complex and specialized that they do not have the ability to regenerate. In come a stem cell which is an immature cell that can become a different cell, or even transform into one of many different cells. Most stem cells can also renew or divide themselves indefinitely. These two characteristics are what present a new pathway to repairing damage to the human body caused by trauma, degeneration and disease. Stem cells keep on generating in the body and take place of the cells which have died such as in a spinal cord injury. The process of using stem cells for spinal cord injury is controversial for some and involves taking one's own bone marrow or a donated human umbilical cord. A licensed anesthesiologist harvests bone marrow from both hips under light general anesthesia in a hospital operating room, the procedure takes about one and half to two hours. The bone marrow–derived stem cells have to pass rigorous testing for quality and to ensure there is not bacterial contamination before they are administered to the patient. In the same fashion ... Get more on HelpWriting.net ...
  • 28.
  • 29. Cord Blood Research Paper Cord Blood Banking is now a huge epidemic nationally. What was once considered to be medical waste is now what is considered a medical breakthrough. Cord blood is stored in two types of banks, both having their benefits and negative aspects. There are many benefits and positive aspects that accompany the banking cord blood. Many of these benefits include but are not limited to the treatment of many life threatening diseases and disorders such as cerebral palsy and childhood cancer such as leukemia. With positives benefits there also come negative aspects. Many of these include who can receive the transplant, the cost of cord blood, the simple fact that the child who the blood came from may never be able to receive that cord blood, and also ... Show more content on Helpwriting.net ... Researchers have discovered that it is actually harder for adults to be treated with cord blood than bone marrow. Children usually receive one unit of cord blood because their small bodies only need a small amount. Adults however need more than the one unit of blood that children receive because their bodies are so much bigger. According to eurostemcells.org there are serious complications of receiveing to few of stem cells. A stem cell transplant containing not enough stem cells may fail or could lead to slow creation of new blood in the body. Doctors have found that if they use two units of cord blood, the transplant will work. When the cord blood is being collected, each newborn only can provide one unit of blood, so when someone needs to receive more than one unit, doctors have to find an almost identical match. There are also many controversies on whether or not cord blood should be collected and banked. Many children's cord blood can't be used by the child who donated it. The cord blood may be contaminated with cells that made that child sick. According to Parent's Magazine "Both the American College of Obstetricians and Gynecologists (ACOG) and the American Academy of Pediatrics (AAP) issued statements in the late 1990s opposing the use of for– profit banks –– and criticizing their marketing tactics. Instead, they recommended that parents donate cord blood to public banks, which make it available for free to anyone who ... Get more on HelpWriting.net ...
  • 30.
  • 31. Cord Blood Celligenics: A Case Study I will request that my (Healthcare Professionals) doctors, midwifes and nurses collects the Cord Blood using the Collection Kit provided by Celligenics. I understand that, under normal circumstances, collection should never affect with the birthing process and cause me no discomfort or pain. I understand that there may be complications at birth that will make it impossible or challenging to collect the Cord Blood, and for these reasons my Healthcare Professional will be enabled to refuse to collect the Cord Blood. I understand that there is a risk of bacterial and/or fungal contamination when collecting Cord Blood. The contaminating bacteria and/or fungus is usually a naturally occurring contaminant of the birthing canal. Celligenics ... Get more on HelpWriting.net ...
  • 32.
  • 33. Cord Blood Case Study Michelle and Jayson Whitaker have been married for a couple of years. Michelle is 33 years and Jayson is 35 years old. They always dreamed of having a happy family, in which they wanted to have only one son. After one year of their marriage, god blessed them with one, whom they name Charlie. Unfortunately, Charlie was diagnosed with a life threatening blood condition known as Diamond Blackfan Anaemia. The Whitakers thought that the only solution to cure their one beloved son was to have a sibling, a donor for Charlie. After the success of the Nash's family, they were encouraged to screen embryos to give birth to a healthy child that would be a perfect cell match for Charlie, so they applied for the allowance to do that. At first, the HFEA refused their request as Charlie's condition is not genetic and such a technique will not do that much of a help. But the Whitakers didn't give up and went to the USA were the policies are not as strict. After some considerable stress, Jamie was born and was able to be a successful donor for Charlie by providing umbilical cord blood. ... Show more content on Helpwriting.net ... 2– Do you think that it is ethical for the parents to agree on donating tissues as cord blood? 3– If such a procedure required an invasive process that would harm the new child, what do you believe the right thing to ... Get more on HelpWriting.net ...
  • 34.
  • 35. St. John Hospital Of Detroit On The Labor And Delivery Unit My clinical rotations are at St. John Moross Hospital in the city of Detroit on the labor and delivery unit. "St. John is a regional–referral teaching hospital with 772 licensed beds, a 1,200 member medical staff and more than 50 medical and surgical specialties. It is also the largest acute–care provider and a designated Emergency Trauma Center. St. John's service area consists of the city of Detroit, and the counties of Wayne, Macomb and St. Clair Counties where over 80% of their patients reside. The total population for this service area is 2,875,367 with slightly more males than females. Also, 61.8% of the population is white, 28.6% is Black non–Hispanic, 4.3% Hispanic, 2.5% is Asian& Pacific Islander (non–Hispanic) and 2.7% are categorized as other" (Taueg, C, 2012). The goal of the health system is being committed to providing spiritually centered, holistic care, which sustains and improves the health of individuals in the communities we serve, with special attention to the poor and vulnerable. My OB clinical experience has been great! I have gained a lot of experience and knowledge from my clinical professor and the nurses on the unit. I have learned so much. In the beginning I felt confident going in and talking to my patients but not caring for them. I was not confident about reading the EFM strips or even touching a patient in active labor due to their pain. Even at the end I still was not comfortable dealing with patients in extreme pain I think that's a learning ... Get more on HelpWriting.net ...
  • 36.
  • 37. The New Method Of The Creation Of Savior Critics argue that permitting the creation of savior siblings through PGD is the first step down a slippery slope that ends with frivolous reasons for selecting an embryo over another. The procedure would open the door for parents to decide on specific characteristics of their babies. This is the creation of fully–fledged 'designer babies'. As in the words of Josephine Quintavalle , "the new technique is a dangerous first step towards allowing parents to use embryo testing to choose other characteristics of the baby, such as eye color and sex". For this reason, the creation of savior sibling is ethically impermissible since if one supports savior sibling, it is impossible to not support the permissibility of designer babies. This argument ... Show more content on Helpwriting.net ... Therefore, there is no reason why there cannot be a special process that allows selection for a certain purpose and not others. It is distinctly different selecting for a specific HLA match to save the life of a dying child and selecting for the color of a baby's eyes. One ought to accept that savior siblings and other designer babies are morally different, and therefore, one can support the idea of a savior sibling while rejecting the concept of a designer baby. In the case of the former, the prima facie case– saving a life, as concluded by Sheldon and Wilkinson, for permitting savior siblings' selection is much stronger than permitting designer babies because there is an important reason for the first but not for the second (535). The value of a person's life is of much greater value the color of another's eyes or hair or their height and weight. Therefore, the cases ought to be viewed differently, "even if there is a slope there is no reason to believe that there will be a slide and there are important differences between savior siblings and designer babies which the slippery slope argument overlooks" (Sheldon and Wilkinson 535). At the same time, one cannot be naïve and fail to think that there are real issues that are morally questionable lurking with the possibility of allowing savior siblings. In the following section, I will look at the question of what ... Get more on HelpWriting.net ...
  • 38.
  • 39. Cord Blood Sampling Introduction Percutaneous umbilical cord blood sampling (cordocentesis) is a diagnostic test. In this procedure, a small amount of blood (fetal blood sample) is taken from the umbilical cord and examined for certain blood disorders and problems in the chromosomes of the unborn child (fetal chromosome abnormalities). It is usually done after the 18th week of pregnancy. This test may be used to diagnose these conditions in the unborn baby (fetus): Infections, including those caused by: A virus, such as rubella. A parasite, such as toxoplasmosis. Bacteria. Birth defects. Blood problems, such as anemia. Bleeding disorders, such as: Hemophilia A or B. Von Willebrand disease. Tell a health care provider about: Any allergies you have. All medicines you are taking, including ... Show more content on Helpwriting.net ... This sample will be compared with the fetal blood sample. You will be asked to lie down on an exam table. An IV will be inserted into one of your veins. You will be given one or more of the following: Antibiotic medicine to help lower your risk of infection of the uterus. A medicine to numb the area (local anesthetic). It is normal to have some cramping while the procedure is being performed, even after getting this medicine. This is temporary. An ultrasound will be done to determine the exact position of your baby. A needle (syringe) will be inserted through the skin and into the umbilical cord to draw a small amount of blood. The needle will be removed. The needle insertion site will be covered with a bandage (dressing). The umbilical cord blood sample will be sent for testing. The procedure may vary among health care providers and hospitals. What happens after the procedure? Your heath care provider will monitor you and your baby to make sure there are no problems before you go home.
  • 40. If your blood is Rh negative, you may need a Rho (D) immune globulin shot to help prevent complications from the test. Ask your health care provider if you need to have this ... Get more on HelpWriting.net ...
  • 41.
  • 42. Nervous System The Nervous System The nervous system is the most complex part of the body, as they govern our thoughts, feelings, and bodily functions. It is an important factor in science because it can lead to new discoveries for cures or diseases. The studies of the nervous system helped lower death rates from heart disease, stroke, accidents, etc. The nervous system is a network of neurons (nerve cells) that that sends information to the brain to be analyzed. Neurons live both in and outside the central nervous system. Understanding how the neurons work is vital to understanding the nervous system. Neurons The neuron has two important structures called the dendrite and axon, also called nerve fibers. The dendrites are like tentacles that sprout from ... Show more content on Helpwriting.net ... Central Nervous System The brain and spinal cord forms the Central Nervous System. The spinal cord gathers information from the neurons and sends it to the brain, but not all nerve impulses get sent to the brain. Only a few impulses reach the brain, and an even smaller number reaches the part of the brain where they cause awareness. The brain and spinal cord is made up of gray and white matter, as well as the various nerve cells. The brain is divided into three parts: the forebrain, midbrain, and hindbrain. The forebrain is called the cerebrum, the largest and most developed part of the human brain. It is divided by the longitudinal sulcus, a deep crevice that separates the forebrain into the left and right cerebral hemispheres. Each hemispheres control the motor (movement) and sensory (sight, smell, hearing, taste, and touch) functions of the other side of the body. The two hemispheres are divided into four lobes: the frontal, parietal, occipital, and temporal lobe. The frontal lobe is involved with muscle control from head to toe. The parietal lobe obtains sensory information from the skin and muscles. The occipital lobe receives information from vision, and the temporal lobe controls speech. Although the four lobes do different jobs, they communicate with each other to allow the brain to coordinate a response. The cerebrum combines the mixtures of sight, sound, smell, and ... Get more on HelpWriting.net ...
  • 43.
  • 44. Selective Inos Inhibitor Specific Aims We propose to modify the recently discovered natural product terpenoids to develop a selective iNOS inhibitor with improved in vivo properties. Specific Aim #1: To confirm and enhance bonding of terpenoids to iNOS. A SILAC experiment will allow the action of the small molecule on iNOS, eNOS, and nNOS to be confirmed. SAR studies will then be performed to enhance selectivity towards iNOS and improve pharmacological properties. Specific Aim #2: To study the effects of iNOS inhibition on angiogenesis. The development of vessels from human umbilical stem cells in the presence of either one of our terpenoids, a traditional iNOS inhibitor, a genetic knockdown, or a control will be studied to determine the effect of iNOS inhibition ... Show more content on Helpwriting.net ... Provided the natural product does not simply quench nitric oxide, further testing will be performed. Alternatively, if the natural product does show activity towards nitric oxide, it will be modified to a moiety less sensitive to the radical before further testing is performed. To test for the selectivity of these molecules SILAC testing will be performed. Using the computer dock data from the terpenoid paper, a bead will be attached to the small molecule near the isopropyl group, which does not seem to be involved in any major interactions in the active site. This bead placement will need to be confirmed experimentally by testing the nitric oxide production of cells in the presence of the compound and the compound with the bead are similar. After the location of bead placement is determined, one set of cells will be grown with the small molecule in heavy medium and another control set of cells in regular medium with no compound. After incubation, the proteins that have attached to the small molecule can be determined through mass spectroscopy will be ... Get more on HelpWriting.net ...
  • 45.
  • 46. Embryonic Stem Cell Research Essay Research on stem embryonic stem cells We live in a world where genetic sciences have gone beyond laws, and past the imagination. We have come to a point where we don't know anymore what is right, and what is wrong. We have to decide. In fact, studies are made on embryonic stem cells that for now have the purpose to better our overall health. These stem cells are extracted from extra IVF embryos; they are used and destroyed. While it's true that this research could cure serious illnesses as Parkinson's, Alzheimer's, and orphan diseases for example; however, it's also true that ending a potential life is immoral and illegal. We could definitely find an alternative to the embryonic stem cells to develop the science. An embryo is a life. ... Show more content on Helpwriting.net ... No one gave us the right to take advantage on him and then kill him, and as noted in experiment– resources.com: "humans should not be trying to play God". Fortunately, most of the leaders in the world share this same opinion. During long years, governments of developed countries weren't certain of what to do about this subject. They took different positions depending on the techniques that were used: if the embryo was an extra IVF embryo or if it was created on that purpose; and on the consequences the researches would have on him. Today, according to www.bionetonline.org , most of European countries such as France, Germany or Spain do not allow embryonic stem cell researches. In United States, during Bush's administration, during 8 years, federal funding were not given for embryonic stem cells researches. Indeed, in a letter to the House Members, NIH Director Zerhouni said: "the president's position is still predicated on his belief that taxpayer funds should not sanction or encourage further destruction of human embryos that have at least the potential for life". Now, according to an article in About.com: U.S Liberal Politics titled: Pros& Cons of Embryonic Stem Cell Research" President Obama have lifted the federal funding ban for embryonic stem cell research". But still, laws are very clear, and even if using embryonic cells is allowed, credible sources such as Wikipedia declare that "the creation of a human embryo ... Get more on HelpWriting.net ...
  • 47.
  • 48. Pros And Cons Of Cord Blood Banking country are now recommending collecting the cord blood. "There's only two things that (you can) potentially buy your new baby that are lifesaving: One is a good car seat and the other is cord blood." Dr. Marra Francis, Ob/Gyn, CBR medical consultant gives his medical and personal opinion of collecting cord blood. Cord Blood banking also has it's limitations. Researchers have discovered that it is actually harder for adults to be treated with cord blood than bone marrow. Children usually receive one unit of cord blood because their small bodies only need a small amount. Adults however need more than the one unit of blood that children receive because their bodies are so much bigger. According to eurostemcells.org there are serious complications ... Show more content on Helpwriting.net ... "Sick children whose parents did bank their blood sometimes cannot be used (Moniger, 67). Many blood banks do not tell parents that if their children may develop a cancer or a disease early on in their life that they may not be able to use the cord blood because the blood may be diseased. This risk is one of the main risks that deter parents from paying the cost for banking. Another negative aspect of cord blood collection and banking is that if a mother who delivers twins would like to collect and store her children's cord blood, she would not be able to. Both babies may have a different cord tissue type and they may be mixed during the collection process making them virtually useless" (The Truth about Cord Blood Banking– Lucie's list, n.d.) . Also, If the mother ever had cancer, she can not have her child's blood collected. This is because doctors do not want the possibility of the cord blood to be contaminated with the cancer which in turn will contaminate the patient receiving ... Get more on HelpWriting.net ...
  • 49.
  • 50. Essay on Stem Cell Research Stem Cell Research INTRODUCTION A child is born everyday and without realizing it, the material that is routinely discarded after the birth could one day be life saving for that person, someone else in the family, or even a complete stranger. This material is the umbilical cord, and the blood contained within their vessels. One may wonder, why is this blood so important? Medical research has discovered that the residual umbilical cord blood contains stem cells. These cells are the building blocks that the body uses to create some of the key components of the human immune system, blood and bone marrow. Stem cells are essential for life, they carry oxygen, fight infections and platelets that form clots on injured body parts. So if ... Show more content on Helpwriting.net ... To date the procedure has been performed on a patient upwards of 230 pounds. (http://www.caner.umn.edu/page/research/cord2.html). The blood is then cryogenically stored at – 385 degrees Fahrenheit in a private or public blood bank. WHO BENEFITS Once the blood is collected, what happens to it? Parents choose whether they want their child's blood reserved for "Directed donation" or "Public donation". With Directed donation the blood collected from the newborn will only be used for treating a blood disease of a sibling or immediate family member. It will be labeled and stored until it is needed. If a parent chooses Public donation, their baby's cord blood will be donated to a general blood bank that anyone might use. SOCIAL AND ETHICAL QUESTIONS RAISED If parents choose a Directed donation, the blood will remain in a private blood bank at an average cost of $1500, plus an annual storage fee of about $100 (source: American college of Obstetrics and Gynecology). To some people, that may seem like a small price to pay for all the potential benefits cord blood can provide, but what are the chances that one of their children or a family member will ever need to use it? Many private cord banks selling cord blood banking as a sort of "biological insurance" – just in case something happens. Experts in blood banking and bone marrow transplantation frown upon this; they argue that people are being frightened into ... Get more on HelpWriting.net ...
  • 51.
  • 52. Cord Blood Bank Essay This Scientific Session will explore scientific and technical advances that forecast a dynamic future for cord blood and cord tissue therapies. Presenters will discuss various models and tell how public and family banks are positioning themselves within the medical field. Since the first human cord blood transplant (UCBT) performed back in 1988, much has been learned about UCBT. Cord blood banks have been established worldwide for the collection, cryopreservation and distribution of UCB for HSCT. Today, a global network of cord blood banks and transplant centres has been established with a large common inventory of more than 700 000 UCB units available, allowing for more than 40 000 UCBT worldwide in children and adults with severe hematological ... Show more content on Helpwriting.net ... In addition, innovative approaches using non–haematopoietic stem cells from cord blood and placenta could be used for treatment of auto–immune diseases or for regenerative medicine. Recently, the number of cord blood transplantation has declined because of the increased use of unmanipulated cells of family haploidentical donors and the use of cyclophosphamide post– transplant. Preliminary comparative results show, a similar early outcomes but the follow–up is still too short to give recommendations for the choice between unrelated cord blood transplant or family haploidentical mismatched transplant Dr. Paramjit Dhot will give general overview of Cord Blood Banking and Transplantation. Dr. Revathi Raj will explain the modalities of cord blood transplantation for various malignant and non malignant hematological conditions in Apollo Hospital Chennai. Dr. Joanne Kurtzberg (confirmation awaited) will discuss Cord Blood transplantation in Neurological Disorders. Dr. John Whener (confirmation awaited) will inform the audience about ex–vivo expansion of Cord blood stem cells and discuss the future horizons in Cord Blood Banking and Cellular ... Get more on HelpWriting.net ...
  • 53.
  • 54. The Ongoing Debate Over the Use of Stem Cells Essay In the past two decades, many technological and scientific advances have been made in order to make life easier for many people who suffer from cancer, disease and sickness. Among these advances there is something revolutionary called stem cells. Stem cells can help restore and regenerate almost all parts of the human body such as the heart, kidney, liver, and many other organs. Although stem cells offer a lot, there are many views against and for stem cells, and among these views lies the debate of whether stem cells should be legalized or not (NIH 2). Stem cells offer exciting new opportunities in the field of science such as regenerating human body parts, but many people are still debating whether or not the use of stem cells is ... Show more content on Helpwriting.net ... In order to get stem cells from embryos, the embryo must be destroyed, and many people view this as killing a human, making it immoral. These embryonic cells can be given different tasks such as making a specific organ, and this is how different body parts can be made. Stem cells have been published in newspapers since 1998, but no institute or company invested money or time into stem cells until 2001, when the Canadian Institute of Health Sciences decided to fund the research of stem cells. Stem cells have three general properties, which are being capable of dividing and renewing for long periods, they have to be unspecialized, and they have to be able to give rise to specialized cells (NIH 3). Stem cells are unspecialized cells in embryos and umbilical cords that can be modified using signals in order to make specialized cells which then have the ability form into various different body parts such as livers, kidneys, hearts, and other major organs. The process of when an unspecialized stem cell turns into a specialized stem cell is called differentiation (NIH 1). In order for unspecialized stem cells to become specialized, one of the two types of signals should be used. The first signal is called internal. Internal signals occur inside a cell by its own genes, which are encoded on strands of DNA. The second signal is called external and this is possible with external support such as chemicals, physical contact, or other molecules in the ... Get more on HelpWriting.net ...
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  • 56. Tranformation of the Medical Industry Due to Advances in... Over the years, medical industry has shaped and transformed due to the recent advance in technology. It affects how we live and what we fear disease wise. With the incredible technology we have now we've been able to gather more research about ourselves, like our DNA and cells. We've been able to clone, create artificial organs, re–write our traits and even predict what we might have in the cancer. We can also make designer drugs, and how much better the market for them can get over time. With technology advancing every day of our lives soon we'd be able to create whole humans with different functions born to do certain things, literally. DNA is known as deoxyribonucleic acid. Deoxyribonucleic acid is a self–replicating material that is known to be in almost every living organism. DNA is shaped like a twisted double helix and is composed of long strands; sugars, phosphate groups as well as nitrogenous bases. This is organized into structures called chromosomes and placed within the nucleus of our cells. DNA contains our genetic information needed for the production of our other cells productions. The history of genetic research began with Gregor Mendel or the "Father of Genetics". His study of plants and reproduction brought interest to the study of genetics. Around the same time as Gregor had conducted his studies, Friedrich Miescher discovered a substance called "nuclein", he isolated a sample of what we know now as DNA. After his findings, his pupil, Richard Altman, ... Get more on HelpWriting.net ...
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  • 58. Cord Blood Cord blood refers to the blood that remains in the blood vessels of the placenta along with the umbilical cord that it is attached to. Also known as placental blood or umbilical cord blood, cord blood contains red blood cells, white blood cells, platelets and plasma. It is also rich in blood– forming (hematopoietic) stem cells. These are similar to the ones found in bone marrow. Due to its similarity with bone marrow, cord blood may be used for transplantation. Storing this blood can potentially be used as a form of treatment for a child, should they become ill. The reason for this is because, stem cells present in the blood can become any human cell. By storing this blood, it not only helps the individual from whom the extra blood came from ... Get more on HelpWriting.net ...
  • 59.
  • 60. Cord Blood Research Papers Trash to Treasure The Pinterest world has changed the way we view trash. Things once tossed in the garbage now hang on walls and adorn porches. Old milk cans, wooden pallets and chipped mason jars now have a hundred new uses. These recycling trends that have been born this century don't end at making living rooms more stylish, but extend to improving and saving lives. Technology is emerging to harvest once discarded after birth and preserving it for research and treatment. Cord blood banking is not only more ethical, but more efficient than its competitors and is therefore the future of stem cell research. Shortly after an egg is fertilized stem cells begin to form. These cells are programmed to form every organ and tissue in the body as the baby develops. ... Show more content on Helpwriting.net ... A limited amount of stem cells can be extracted from after birth, but these few cells can mean a longer or improved life for someone (Bergman). In addition, people believe that harvesting cord blood cells steals the cells from the child. The umbilical cord is cut and clamped just like a typical delivery (CariCord). Delayed clamping, in which the cord is left attached to drain the blood back into the baby, still allows the afterbirth to be donated. The science behind cord blood banking is still developing because these treatments have only been performed for a little over ten years and the only way to overcome that is to move forward with research (Stem Cell). Cord blood cells hold the potential of becoming brain and heart cells and combatting serious neurological diseases. The science is young, but one out of every three hundred kids are plagued with cerebral palsy and one of every sixty–eight children battle autism (What It Is). The chance of helping people throughout the world live a better life fuels the need for an increase of support in this budding ... Get more on HelpWriting.net ...
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  • 62. Umbilical Cord Blood There are so many people in this world today that are diagnosed with blood disorders, and other cancerous diseases. Along these terrible diseases comes a long, painful journey of treatments, like bone marrow transplants. But, bone marrow transplants aren't the only transplants in this world now. "In the outstanding findings of 1980 an estimation of more than 130 million infants are born, and umbilical cord blood (UCB) is known to be the most abundant reservoir of hematopoietic cells for many clinical applications." (Waller–Wise R.) Umbilical cord blood has many potential usages, yet mothers don't know about it. Instead of using the umbilical cord blood, doctors usually just dispose of it. What mothers don't have the knowledge of is that ... Show more content on Helpwriting.net ... This is because one unit of umbilical cord blood won't affect adults whatsoever. There aren't enough hematopoietic stem cells in one unit. This is why scientists and clinical trials are doing their best to come up with a way to double the unit so adults are able to use it, and not just adolescence. Scientists are also still studying more ways to treat diseases with cord blood. At Duke University, for example, researchers are using patients' own cord blood in trials for cerebral palsy and Hypoxic ischemic encephalopathy (a condition in which the brain does not receive enough oxygen). Trials are also under way for the treatment of autism at the Sutter Neuroscience Institute in Sacramento, California. Also, according to the New England Journal of Medicine, cord blood is still better than marrow transplantations after studies were done. The adult patients in the trial had advanced leukemia, and were then give a bone marrow transplant, but recovery was slower because they weren't matched. On the other hand, the leukemia patients that were given cord blood transplants had more matches than bone marrow, and also had no acute graft–versus–host disease. "A really exciting area that's just now in the basic science lab, is the area where stem cells...can be used for going over to muscle cells like your heart muscle if you had a heart attack...or brain cells if ... Get more on HelpWriting.net ...
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  • 64. Stem Cells And Regenerative Medicine : Cord Blood Banking... Name: Darshana Chaudhary Student Number: s5024975 Course: 7001HSV Applied Research Methods Tutor: Jennifer Boddy Due Date: 14th September 2015 Date Submitted: 14th September 2015 Word Count: 1671 words STEM CELLS AND REGENERATIVE MEDICINE : CORD BLOOD BANKING AND ITS THERAPEUTIC APPLICATION Abstract : Stem cells can give rise to any tissue found in the body and thus provide nearly limitless potential for medical applications . Stem cells have the great potential to develop into many different cell types in the body during early life and growth. They serve as a repair system . Due to unlimited therapeutic applications of stem cells , they continue to be of great importance scientifically and ... Show more content on Helpwriting.net ... Human embryonic stem cells . Patient–specific therapy. METHOD : Articles for this review were selected from Pubmed Central and Medline databases and proquest databases. Introduction : Stem cells are able to generate mature terminally differentiated cells of atleast one lineage and possess the capacity of self–renewal .Stem cells can be categorized as totipotent, pluripotent or multipotent according to their developmental potential. (Takahashi and Yamanaka 2007). Stem Cell Classification Based on Differentiation Potential: Stem cells can be classified based on their ability to differentiate. They are classified into following five types :
  • 65. Totipotent Cells: Totipotent cells are found in early stage of development .The totipotent cells forms the embryo and the placenta and differentiate into both embryonic and extraembryonic tissues. Pluripotent Cells: Pluripotent cells differentiate into cells that arise from three germ layers called – ectoderm , endoderm and mesoderm , from which other tissues and organs develop. Oligopotent Cells: oligopotent are capable of self renewal and differente into many tissue types. Unipotent Cells: unipotent cells are capable of self renewal and differentiate into only one single type of cell. Multipotent Cells: They are found in most tissues and differentiate into cells from a single germ layer. (Kolios, 2012) Sources of Stem Cells for Regenerative Medicine: There are a number of cardiovascular , neurological ... Get more on HelpWriting.net ...
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  • 67. How Henrietta 's Cells Were Recovered, And Stored I begin writing this essay about Henrietta Lacks by discussing option number three outlined in this project. Before this class had begun, I could not tell you how or why such vaccines came to be. I can almost relate to the author in the beginning of the book when she is in her college biology course and has no idea who Henrietta Lacks is. This book outlines so many big topic issues, and I feel they all play a role in how Henrietta 's cells were recovered, and stored. From my own personal viewpoint, I feel one of the biggest issues for myself personally, is the bioethics of it all. Working in healthcare and living in this generation, money, is a monumental factor that defines just about everything. "Money, defines how we test drugs, why ... Show more content on Helpwriting.net ... Would she have still if it would not profit her, or her family, but so many others around the world who are sick? Another factor that played a significant role in Henrietta 's life was a combination of not only poverty, but racism too. The book calls into question the name Henrietta Lacks. "We are officially introduced to Henrietta as Loretta Pleasant. Henrietta, or also known as Loretta, grew up with eight other siblings, and an abusive father." (Biogrophy.com) Henrietta spent most of her youth living with her grandfather and future husband. During this time in history, Henrietta along with other African Americans, were subjected to segregation. Her life was far from easy, she grew up as many African American children did during those times, working in the tobacco fields. It seems to me that this woman had a tremendously hard life. She endured: her mother 's death, being divided from her family, segregation, child labor working in the tobacco fields, a philandering husband, and cancer to name just a few things. I honestly cannot begin to imagine this lifestyle much less cancer. What stands out to me about her is that I portray her to be this strong, resilient woman. I say this because she refuses treatment for her STDs, goes on sleeping with her husband bearing him children , and most of all, she was a God fearing woman. I can only begin to imagine during this time in history being a woman, much less an African American woman, had its struggles and ... Get more on HelpWriting.net ...
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  • 69. Persuasive Essay On Donating Children Having a child can be one of the most exciting experiences for a parent. However, bringing a child into the world can also be a very scary experience. Every parent's wish is to have a healthy baby, but sadly this is not always a reality. When a child is born with a disease the whole dynamic of a family changes, doctor visits and medication become the new norm. Sometimes families are even faced with the difficult decision of life or death for their child, which can only be cured by using donations from a close match. Depending on the person, the likelihood of finding your perfect match from the donor list can be slim. With that having been said, many parents turn to the decision of conceiving another child to be the donor for their already living ... Show more content on Helpwriting.net ... There are many people who are opposed to conceiving a child to be used as a donor, so it is important we acknowledge their oppositions. There are three main points against the conception of children for the use of stem cell donations. The first is explained by Elaine R. Morgan, from an article titled Having a child to save a sibling, "the emotional endangerment of the child because of the motivation for its conception." (Morgan, ET.AL, 1). Morgan brings up a very valid point, often– times the child who is donating begins donations from birth. As a very young donor, the child may not fully understand the procedures. It is also a very heavy concept to weigh on a child, that their sibling could die without their help. Jennifer P. D'Auria adds to Morgans findings on emotional endangerment of a child, in an article titled Through the eyes of young sibling donors, she described children remembering "immense pressure and emotions they felt to be that perfect match". Although it can be extremely taxing on a child to have life or death weighing on them, D'Auria assessed 44 children and majority felt there was no question in whether or not they wanted to step up to save their sibling, "To me there was no choice. It was you can either have a brother or you cannot have a brother. That was my choice". Morgan and D'Auria can both agree that there are emotional risks when going through a procedure like this, there is no guarantee that it will work so if it didn't the child may certainly be emotionally unstable. But what D'Auria explains through the research with many patients, is that the child willingly wants to help their sibling, they would do anything for them. Every medical procedure has risks and as medical technology continues to advance, the risk of procedures has been decreasing. When Morgan claims that children ... Get more on HelpWriting.net ...
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  • 71. A Research Study On Umbilical Cord Blood Umbilical cord blood (UCB) contains a substantial number of stem cells that have the potential to be used in various transplants to treat a variety of immunodeficiency, oncologic, hematologic and/or genetic disorders. UCB is found most commonly in the blood of newborn babies. Once the baby is born, the blood that remains (that was previously thrown away as 'medical waste') in the umbilical cord and placenta can be taken and stored, to be used later for transplantation or research (Pandey, Kaur & Kamath, 2016). Recent studies in the last decade have shown that UCB is a great source of stem cells, which makes it a valuable resource in the field of stem cell therapy. Stem cells have amazing potential for therapeutic use in tissue repair and regeneration. In October 1988, the first umbilical cord blood transplant was done on a young five–year old boy named Matthew Farrow in France, who was diagnosed with severe aplastic anemia due to Fanconi anemia. The umbilical cord blood was collected at birth from Matthew's newborn sister who, through prenatal testing, had been found to be unaffected by Fanconi anemia and was HLA– identical to Matthew. The UCB was cryopreserved and taken from Indiana to France, where it was then thawed and injected into Matthew. There was no evidence of graft–versus–host disease, and according to Ballen, Gluckman and Broxmeyer, as of 2013, Matthew is "healthy with complete long–term hematological and immunological donor reconstitution 25 years after ... Get more on HelpWriting.net ...
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  • 73. The Ethical Dilemma Of Hepatitis Sachs Disease Often times in a complex situation individuals are involved in conflicting decisions to progress to a solution. The ethical dilemma may conflict with acceptable morals or behaviors but to resolve the paradox a decision has to be made. D.B.'s parents are faced with an ethical dilemma when they discover their son has an incurable disease. They could allow the illness to take its course or seek a form of treatment to slow its progression. Ethical Dilemma D.B. was born May 30, 1999, with a condition most commonly known throughout the Eastern European Jewish community. Tay–Sachs disease is a condition caused by a lack of hexosaminidase A (Hex A) enzyme in the brain used to breakdown gangliosidosis (GM2) enzymes or the brain begins to swell, ... Show more content on Helpwriting.net ... would recover and have a chance to survive the disease. The parents made a decision for their son in hopes the odds would be in his favor. ANA Code of Ethics Provision two, four, and six are a few ethical principles relevant and applicable to the situation. The healthcare team respected the clients wishes, committed to the client's health, took accountability for care and practice, and contributed to the healthcare environment. Provision Two: Primary commitment is to the patient, whether an individual, family, group, community, or population. Provision Four: Authority, accountability, and responsibility for nursing practice; makes decisions; and takes action consistent with the obligation to promote health and to provide optimal care. Provision Six: Through individual and collective effort, establishes, maintains, and improves the ethical environment of the work setting and condition of the employment that are conductive to safe, quality healthcare. (Hegge, 2015). Relation of the ANA Code to the Dilemma American Nurse Association Code of Ethics principles relates to the care provided for the client while under supervision of the healthcare team during their dilemma. The healthcare team establishes principles to abide by in order to provide optimal, safe, efficient care for their clients. The team successfully met the goals of the fourth provision by "making decisions and taking action consistent with the obligation to promote health ... Get more on HelpWriting.net ...
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  • 75. Cord Blood Case Study Did you know that cord blood can treat over 80 medical conditions and diseases? Cord blood refers to residual blood that's present in the placenta and umbilical cord immediately after a baby is born. This blood can be gathered and stored to treat various types of illnesses and medical conditions. When harvested immediately after the birth of a baby, cord blood has a number of stem cells that can take the form of other cell types in the body such as fat, liver, muscle, nerve, and blood cells. Here are five types of medical conditions the harvested blood can treat. 1. Cancers A number of cancer types, among them leukemia and lymphoma, can be treated with cord blood. Cancer, which can decimate a patient, is characterized by constant pain, weight ... Show more content on Helpwriting.net ... These disorders occur as a result of cellular structure imbalances in the body and can cause blood clots, swelling, and excessive bleeding. Specifically, cord blood can be used to treat a variety of blood diseases such as congenital amegakaryocytic thrombocytopenia, amyloidosis, essential thrombocythemia, pure red cell aplasia, and many others. 3. Metabolic Disorders Cord blood can be used to treat metabolic disorders such as krabbe disease and hurler syndrome, which have been known to cause weight loss, seizures, and frequent body pain. These medical conditions can be life–threatening. Cord blood can be used as a treatment option for patients with other metabolic disorders as well, such as sly syndrome, tay sachs, niemann–pick disease, and lesch–nyhan syndrome, among many other conditions. 4. Immune Disorders Cord blood can also be used to treat immune disorders such as myelokathexis and evans syndrome that cause the body to attack itself. The resulting frequent fevers and fatigue can be very debilitating. In some cases, immune disorders can be fatal. Among immune disorders that can be treated with cord blood include severe combined immunodeficiency diseases, hemophagocytic lymphohistiocytosis, and many other medical ... Get more on HelpWriting.net ...
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  • 77. Stem Cell Research: The Benefits of Stem Cells Essay In Brazil 2009, there was an 18 year old boy that had half of his jaw and teeth removed because of a tumor. Scientists took some of his bone marrow and extracted the adult stem cells from it and formed an osteoblast, which is a bone forming cell. Six months after the osteoblast was injected, it started forming new bone material which filled the gaps (NIH Stem Cells). Stem cells could be a genius way to treat many diseases and disorders and it should be supported by everyone. Stem cells get their name from the fact that they are basic cells that other cells develop from. They are capable of developing into a wide range of cells. Stem cells could potentially be used to grow new cells to replace the cells that were destroyed or damaged by ... Show more content on Helpwriting.net ... Scientists need to know that all the stem cells completely change into the tissue to avoid negative side effects, like tumors, when the cells are implanted in patients. Scientists also try to experimentally treat diseases with no cure with stem cells by implanting them into animal models, like mice (Freedman 13). Many different groups of people protest stem cell research. Some protesters say that getting stem cells from embryos amounts to killing a person to improve the life of another (Freedman 18). People protest stem cell research even though the embryos and fetuses would be discarded anyway (Freedman 19). They think if it is accepted, they will start experimenting on people who are going to die, like death row inmates and terminally ill people (Freedman 22). Some supporters of stem cell research say that using tissue from dead embryos is equivalent to transplanting organs from people that died from homicide or suicide. They say stem cell experiments in animals have already shown improvements in disorders. Treatments for diseases and disorders can't be developed if experiments aren't performed. There are a lot of potential uses of stem cells, but there are obstacles that we need to go through first. Stem cells can be used to test new drugs that scientists make. We could generate healthy heart muscle cells with stem cells. Injected cells could repair things in the body by secreting growth factors. Before scientists start ... Get more on HelpWriting.net ...
  • 78.
  • 79. Symptoms And Symptoms Of Krabbe 's Disease Krabbe's disease has many signs and symptoms. There are three stages of this condition in infantile form. Stage 1: The infant is seemingly normal and healthy for the first couple months after birth. However during early onset of this disease, the child has signs of incoordination, vomiting, irritability, unexplained fevers and stiff posture. Initial symptoms that may occur are seizures (Wenger 2000). There is slight developmental regression and behavioral abnormalities, in particular, displaying hypersensitivity to sound and touch (ORDR). Throughout this stage, the Cerebrspinal Fluid (CSF) protein concentration at this point is significantly increased (Wenger 2000). The CSF is a liquid that bathes the brain and spinal cord. Its function is to cushion the brain and spinal cord, protecting against injury. It also circulates chemicals and certain nutrients that are filtered from the blood and it also removes waste products from the brain (Lantos 2011). The second stage of Krabbe's disease involves aplasia and hypoplasia, which is a defective development of the abdominal wall musculature. There is also hypertonia, which is damage to the Central Nervous System (CNS). The CNS is the brain and the spinal cord, which controls most of the functions of the body and mind. There is also visual impairment, sensorineural hearing loss (SNHL), cognitive impairment, and electromyography (EMG) abnormalities (ORDR). These symptoms vary from person to person (Wenger 2000). Some less common ... Get more on HelpWriting.net ...