Introduction of rabies virus and how it cause

1. RABIES
VIRAL
DISEASE

2. INDROTUCTION :
rabies is a preventable
viral disease most often
transmitted through the bite
of a rabid animal. The rabies
virus infects central nervous
system of mammals,
ultimately causing disease in
the brain and death.

4.  On July 1885 louis
pasteur and his
collegues injected
the first of 14 daily
doses of rabbit
spinal cord
suspensions
containing
progressively
inactivated rabies
into 9year old boy
joshep meister. Who
had been severaly
bitten rabid dog 2
days before

6. How to rabies virus
affect animals?

8.  The incubation time of
virus is 2to 3month
 Based on, conc.of
inaculum
 Host age and immune
system
 Prodromal phase
 Head ache, fever,
mental proplems
 hydrophobia

10. DIAGNOSIS;
 [CPE] cytopathic effect- negri
bodies- affect neurons
 RT-PCR
 Cell culture
 ELISA

11. TREATEMENT PREVENTION AND
CONTROL;
 Local treatement of wound
 HRIG and HDCR vaccine used
 Intravascularly- 3, 7, 14,28th
 Intradermally- 0,3,7,28,90th
 Vaccine animals
 Maintain – distance

12. thank
you