A man was under treatment for infertility. Examination of his sperm showed that his sperm could not swim. He also suffered from chronic bronchitis and other respiratory problems in which mucus with trapped particles was not being cleared from his lungs. From this you might infer he has a genetic defect affecting which structures inside his cells? Solution Ans: He has a genetic defect affecting T cell inside his cell. Because, he might have AIDS for which the percentage of motile sperm become decrease. In AIDS, HIV targets T-helper cell(CD4) which leads to cell death. T helper cell also play a vital role in regulation of immune response to invading microorganism. If in AIDS, T helper cell become inactivate microorganism (like influenza or RSV virus or rhinoviruses) can easily invade into the cell which cause acute bronchitis..