Sally\'s brother is color-blinded. Her husband is normal. What is the chance for her son to be color-blinded? Solution Answer:one in two (50%) chance Color blindness is X linked recessive inheritance. two copies of a disease allele on the X chromosome are required for an individual with two X chromosomes (a female) to be affected with an X-linked recessive disease. Affected males transmit the disease allele to all of their daughters, who are then carriers, but to none of their sons. Therefore Sally’s brother must have got the disease X chromosome from her mom. Sally must be carrier. For a carrier female, with each pregnancy there is a one in two (50%) chance her sons will inherit the disease allele..