-acute appendicitis (inflammation of the vermiform appendix) requires immediate surgical removal of the appendix. in the event that the appendix bursts, its contents are released into the abdominal cavity, which can lead to widespread infection, sepsis, and death. discuss the events that might lead to an enlarged and inflamed vermiform appendix. -following the 2009 H1N1 pandemic, annual influenza vaccines began to include strains for H1N1 influenca. Discuss the purpose of vaccines and state how vaccines may protect against disease outbreak. Solution appendicitis is obstruction of the lumen of the appendix followed by infection. In 60% of patients, obstruction is caused by hyperplasia of the submucosal follicles. This form of obstruction is mostly observed in children and is known as catarrhal appendicitis. A fecalith or fecal stasis causes luminal obstruction 35% of the time and is usually observed in adults. Obstruction may also be caused by foreign bodies (4%) and tumors (1%). Following obstruction, an increase in mucous production occurs, leading to increased intraluminal pressure. With increased pressure and stasis from obstruction, bacterial overgrowth ensues. The mucus then turns into pus that causes a further increase in luminal pressure. This leads to distention of the appendix and visceral pain, which is typically located in the epigastric or periumbilical region. Purpose of the vaccine: The purpose of vaccination is to produce immunity against particular disease . Many infectious diseases, previously responsible for millions of deaths, are being controlled through vaccination. Some, such as smallpox, polio have been eradicated through vaccination. How vaccines protect against diseases? Vaccination comes under passive immunisation , where already existed antibodies are extracted from other organisms which are infected with the disease. These antibodies injected into the persons body to give immunity against the same disease in future..

1. -acute appendicitis (inflammation of the vermiform appendix) requires immediate surgical
removal of the appendix. in the event that the appendix bursts, its contents are released into the
abdominal cavity, which can lead to widespread infection, sepsis, and death. discuss the events
that might lead to an enlarged and inflamed vermiform appendix.
-following the 2009 H1N1 pandemic, annual influenza vaccines began to include strains for
H1N1 influenca. Discuss the purpose of vaccines and state how vaccines may protect against
disease outbreak.
Solution
appendicitis is obstruction of the lumen of the appendix followed by infection. In 60% of
patients, obstruction is caused by hyperplasia of the submucosal follicles. This form of
obstruction is mostly observed in children and is known as catarrhal appendicitis. A fecalith or
fecal stasis causes luminal obstruction 35% of the time and is usually observed in adults.
Obstruction may also be caused by foreign bodies (4%) and tumors (1%).
Following obstruction, an increase in mucous production occurs, leading to increased
intraluminal pressure. With increased pressure and stasis from obstruction, bacterial overgrowth
ensues. The mucus then turns into pus that causes a further increase in luminal pressure. This
leads to distention of the appendix and visceral pain, which is typically located in the epigastric
or periumbilical region.
Purpose of the vaccine:
The purpose of vaccination is to produce immunity against particular disease .
Many infectious diseases, previously responsible for millions of deaths, are being controlled
through vaccination. Some, such as smallpox, polio have been eradicated through vaccination.
How vaccines protect against diseases?
Vaccination comes under passive immunisation , where already existed antibodies are extracted
from other organisms which are infected with the disease. These antibodies injected into the
persons body to give immunity against the same disease in future.