A 7 year old female with a history of previous UTI’s suddenly develops painful, dark-orange colored urine, with fever and back pain. Her urinalysis reveals dipstick tests that are positive for protein (2+), blood (1+), leukocyte esterase (4+), and nitrate (4+). The microscopic examination yields 20-25 WBC/HPF, 5-10 RBC/HPF, 5-10 WBC Casts/LPF, and numerous bacteria. The patient has been taking Tylenol and vitamin C supplements daily for the past 24 hours, since the condition began. Based on the results 1) what diagnosis/condition would you surmise at this point? 2) what dipstick/microscopic test support this? 3) is the patient’s history significant? 4) can the medication or vitamin supplement have any impact on the test results? Solution Women often experience urinary tract infections that are often marked by pain in the abdomen or lower back. The urine is dark-orange colored due to blood mixing with dark yellow urine. The infection may be due to bacteria E. coli, (MayoClinic). Leukocyte esterase test dipstick that indicates; the presence of white blood cells either as whole cells or as lysed cells; supports this assumption and the microscopic examination yielding 20-25 WBC/HPF also backs this assumption. Yes with all the medical history and the details of the tests done; one can proceed with the treatment. Yes according to researches; Vitamin C spiking of urine has shown to demonstrate false-negative results at various concentrations, (Ko DH, 2015) in case of Dipstick Test Results..