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Hepatic portal
vein
&
portal
hypertension Submitted by: jyoti
 Group: 21
 Semester: 7th
How did…
…Devdas die?
Portal system
Portal circulation
The portal vein is a blood
vessel that carries all the
deoxygenated blood and
nutrients from GIT and spleen
to liver.
Hepatic Portal Vein
 Origin & end in capillaries / venous
sinusoids
 Size: 8cm X 1 cm
 Diameter 0.8 to 0.9
 Drains
 Abdominal part of alimentary tract
(except lower part of anal canal)
 Spleen & Pancreas
 Conveys absorbed products of
digested food to liver
 Devoid of valves
 Reservoir of blood : 1200 ml / min
Formation
 Union of Sup mesenteric & Splenic vein
 Between neck of Pancreas & IVC at level L2
Course: Extrahepatic part
 Passes upwards & Rt,
behind neck of pancreas &
1st part of duodenum
 Enters rt free margin of
lesser omentum in front of
epiploic foramen with BD &
HA
 Reaches porta hepatis &
divides into rt & Lt
branches.
Course: Intrahepatic part
 Branches of portal vein
 Segmental brs
 Brs in Portal canal
 Hepatic sinusoids
 Central veins
 Sublobular veins
 Hepatic veins
IVC
Tributaries
Tributaries Formative
 Sup Mesenteric vein
 Splenic vein
 Received by Trunk
 Rt & lt Gastric veins
 Superior PD vein
 Received by branches
 Cystic vein
 Paraumbilical veins
 Occasional
 Inf mesenteric
 Rt gastro-epiploic
 Pre-pyloric vein.
Branches
Rt Branch
 Shorter, wider
 Receives cystic vein
Lt branch
 Narrower, longer
 Runs in Porta hepatis
from Rt to Lt
 Brs to Caudate & Quadrate
lobe
 Receives Paraumbilical veins
Parts
3
1
2
• Infraduodenal
• Retroduodenal
• Supraduodenal
 Infra duodenal
 Ant: Neck of Pancreas
 Post: IVC
 Retro duodenal
 Ant: Duodenum (1st Part), Bile duct, GD artery
 Post: IVC
 Supra duodenal : In rt free margin of lesser omentum
 Ant : hepatic artery & bile duct
 Post: IVC
 Surrounded by Hepatic plexus of nerves, lymphatics & LN
Relations
Portocaval anastomosis
The portal venous
system have several
anastomosis with
systemic venous system.
In case of portal
hypertension these
anastomosis may
become engorged ,
dilated or rupture.
Site Caval Portal Effect in
PHT
Lower end of
esophagus
Esophageal
tributaries of
hemiazygos V
Oesophageal
tributaries of
Lt gastric V
Oesophageal
varices
Umbilicus Veins of AAW Paraumbilical
veins
(tributaries of
Lt br of Portal
V)
Caput
medusae
Lower end of
rectum &
Anal canal
Middle & inf
rectal Vs
Sup rectal V Anorectal
varices,
Internal
hemorrhoids
Site Caval Portal
Post abd wall • Lt renal V
• Veins of Post Abd
wall
• Splenic V
• Veins of
retroperitoneal
organs like
duodenum, Asc &
Desc colon
Bare area of liver Diaphragmatic veins Hepatic brs of Portal V
Liver Patent Ductus
venosus (rare)
Lt br of portal v
Post wall of vagina Vaginal venous plx Sup rectal v
Falciform lig Diaphragmatic v Paraumblical v
 > 12 mm of Hg
 Causes :
 Pre hepatic : Thrombosis of portal vein, congenital atresia
 Hepatic: Cirrhosis, hepatic fibrosis: wilsons disease, congenital fibrosis and
hemochromatosis.
 Post hepatic: liver to right side of heart. Hepatic vein thrombosis, IVC
thrombosis, congenital malformation of IVC, constrictive pericarditis.
 Effects: Splenomegaly, Ascites, Collateral
circulation through sites of Portasystemic
anastomosis
Portal hypertension
Signs and symptoms
 Ascites
 Splenomegaly
 Thrombocytopenia
 Hepatic encephalo[athy
 Anastmosis: esophageal varices (bleedings)
gastric varices
anorectal varices
caput medusa(around umbilicus)
Internal piles (Hemorrhoids)
Caput Medusae
Esophageal varices
MANAGEMENT
 HEMORRHAGES : selective beta blockers
 ASCITES: diuretics(spironolactone)
 Antibiotics:vancomycin
 TIPS PROCEDURE:
TRANSJUGULAR INTRAHEPATICPORTAL SYSTEMIC SHUNT
artificial channel within the liver establishing
communication between portal vein and hepatic vein
Portalveinportocavalanatomosis 160518041049

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Portalveinportocavalanatomosis 160518041049

  • 1. Hepatic portal vein & portal hypertension Submitted by: jyoti  Group: 21  Semester: 7th
  • 3. Portal system Portal circulation The portal vein is a blood vessel that carries all the deoxygenated blood and nutrients from GIT and spleen to liver.
  • 4. Hepatic Portal Vein  Origin & end in capillaries / venous sinusoids  Size: 8cm X 1 cm  Diameter 0.8 to 0.9  Drains  Abdominal part of alimentary tract (except lower part of anal canal)  Spleen & Pancreas  Conveys absorbed products of digested food to liver  Devoid of valves  Reservoir of blood : 1200 ml / min
  • 5. Formation  Union of Sup mesenteric & Splenic vein  Between neck of Pancreas & IVC at level L2
  • 6. Course: Extrahepatic part  Passes upwards & Rt, behind neck of pancreas & 1st part of duodenum  Enters rt free margin of lesser omentum in front of epiploic foramen with BD & HA  Reaches porta hepatis & divides into rt & Lt branches.
  • 7. Course: Intrahepatic part  Branches of portal vein  Segmental brs  Brs in Portal canal  Hepatic sinusoids  Central veins  Sublobular veins  Hepatic veins IVC
  • 9. Tributaries Formative  Sup Mesenteric vein  Splenic vein  Received by Trunk  Rt & lt Gastric veins  Superior PD vein  Received by branches  Cystic vein  Paraumbilical veins  Occasional  Inf mesenteric  Rt gastro-epiploic  Pre-pyloric vein.
  • 10. Branches Rt Branch  Shorter, wider  Receives cystic vein Lt branch  Narrower, longer  Runs in Porta hepatis from Rt to Lt  Brs to Caudate & Quadrate lobe  Receives Paraumbilical veins
  • 12.  Infra duodenal  Ant: Neck of Pancreas  Post: IVC  Retro duodenal  Ant: Duodenum (1st Part), Bile duct, GD artery  Post: IVC  Supra duodenal : In rt free margin of lesser omentum  Ant : hepatic artery & bile duct  Post: IVC  Surrounded by Hepatic plexus of nerves, lymphatics & LN
  • 14. Portocaval anastomosis The portal venous system have several anastomosis with systemic venous system. In case of portal hypertension these anastomosis may become engorged , dilated or rupture.
  • 15. Site Caval Portal Effect in PHT Lower end of esophagus Esophageal tributaries of hemiazygos V Oesophageal tributaries of Lt gastric V Oesophageal varices Umbilicus Veins of AAW Paraumbilical veins (tributaries of Lt br of Portal V) Caput medusae Lower end of rectum & Anal canal Middle & inf rectal Vs Sup rectal V Anorectal varices, Internal hemorrhoids
  • 16. Site Caval Portal Post abd wall • Lt renal V • Veins of Post Abd wall • Splenic V • Veins of retroperitoneal organs like duodenum, Asc & Desc colon Bare area of liver Diaphragmatic veins Hepatic brs of Portal V Liver Patent Ductus venosus (rare) Lt br of portal v Post wall of vagina Vaginal venous plx Sup rectal v Falciform lig Diaphragmatic v Paraumblical v
  • 17.  > 12 mm of Hg  Causes :  Pre hepatic : Thrombosis of portal vein, congenital atresia  Hepatic: Cirrhosis, hepatic fibrosis: wilsons disease, congenital fibrosis and hemochromatosis.  Post hepatic: liver to right side of heart. Hepatic vein thrombosis, IVC thrombosis, congenital malformation of IVC, constrictive pericarditis.  Effects: Splenomegaly, Ascites, Collateral circulation through sites of Portasystemic anastomosis Portal hypertension
  • 18. Signs and symptoms  Ascites  Splenomegaly  Thrombocytopenia  Hepatic encephalo[athy  Anastmosis: esophageal varices (bleedings) gastric varices anorectal varices caput medusa(around umbilicus)
  • 22. MANAGEMENT  HEMORRHAGES : selective beta blockers  ASCITES: diuretics(spironolactone)  Antibiotics:vancomycin  TIPS PROCEDURE: TRANSJUGULAR INTRAHEPATICPORTAL SYSTEMIC SHUNT artificial channel within the liver establishing communication between portal vein and hepatic vein