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EXAMINATION OF
RESPIRATORY
SYSTEM
‫سفنت‬‫اظنم‬‫ااحتمن‬
Exam. of RS...Dr Sana Kauser (Pathology) 1
Dr Sana Kauser Ateeque Ahmed
Assistant Professor
Dept. of Mahiyatul Amraz
Al-Ameen Unani Medical College & Hospital, Malegaon
Exam. of RS...Dr Sana Kauser (Pathology) 2
Contents
▰ History taking
 Bio data of the patient
 Chief/ Presenting complaints
 History of presenting complaints
 Cardinal symptoms
▰ Examination of respiratory System
o Inspection
o Palpation
o Percussion
o Auscultation
Exam. of RS...Dr Sana Kauser (Pathology) 3
4
Structures present in the chest cavity
• Diseases of the RS
accounts for third of
deaths
• Major cause of patients
visit to the doctor
• An important part of
systemic examination
Introduction
Exam. of RS...Dr Sana Kauser (Pathology)
1. HISTORY TAKING
‫رمضی‬‫روداد‬
Exam. of RS...Dr Sana Kauser (Pathology) 5
“
”
Basically with history, from
each point you ask the
patient and each answer
you get from the patient,
you understood that yes,
these are probable
diagnosis .
6
Bio data of the patient
Name
Age
Sex
Occupation
Address
Religion
Marital status
7
Exam. of RS...Dr Sana Kauser (Pathology)
Presenting complaints
RESPIRATORY SYSTEM
• History of presenting complaints
• Chronological order (complaints with duration)
• Pain (SOCRATES)
• Cough: Dry or productive
• If productive: Quantity, Color, Nature, Odor, Haemoptysis,
relation to posture, diurnal variation.
• Breathlessness: duration, grade, postural variation, diurnal
variation, seasonal variation,
• History of wheezing
• History of Orthopnea
8
Exam. of RS...Dr Sana Kauser (Pathology)
Others
• History of past illness: Hypertension, DM, TB, HIV,
Exathematous fevers.
• Personal history:
food/appetite, B/B, sleep
addiction-smoking, alcohol, drug addictions
• Family history
• Menstrual and obstetric history
• Treatment history (anaphylaxis, urticaria)
• H/O Fever
• H/o allergies, swelling of feet, palpitations, seizures,
• Surgery under general anesthesia
9
Exam. of RS...Dr Sana Kauser (Pathology)
Cardinal symptoms
The primary or major symptom by which a diagnosis is made
• Cough
• Expectoration/ Sputum
• Haemoptysis
• Breathlessness/ dyspnoea
• Wheezing
• Pain in the chest
Exam. of RS...Dr Sana Kauser (Pathology) 10
Cough ‫اھکیسن‬
Definition: A sudden expulsion of air through the large breathing passages
that can help clear them of fluids, irritants, foreign particles and microbes.
• Acute/ short lived or chronic
• Dry or productive
• Episodic? Time?
• Related to any posture
• Aggravated by Allergens? Pollens? Cold air?
Acute
(lasting <3 weeks)
Recent infections (viral/ bacterial)
Chronic
(lasting > 8 weeks)
Should be Sent for CXR, spirometry
Exam. of RS...Dr Sana Kauser (Pathology)
11
Causes of cough
Causes Examples
Respiratory Viral or bacterial infections
Bronchospasm
COPD
Asthma
Aspiration
Brochiolitis (infection and inflam. of bronchioles in children
and infants)
Malignancy
Parenchymal disease e.g. ILD (progressive scarring)
Cystic fibrosis (inherited, affect mucus and sweat producing
cell, thick & sticky fluids, plug)
Upper airways diseases Post nasal drip
Sinusitis
Inhaled foreign bodies
Tonsillar enlargement
Cardiovascular diseases LVF, Mitral stenosis
Gastro-oesophageal disease GORD
Drugs and irritation ACE inhibitors (prils-antihypertensive), cigarette smoking
Exam. of RS...Dr Sana Kauser (Pathology)
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Cont..
Productive
Chronic
bronchitis
Bronchiectasis
Tuberculosis
Dry
Pharyngitis
Laryngitis
Tracheatis
Tonsillitis
Exam. of RS...Dr Sana Kauser (Pathology) 13
Sputum/ Expectoration‫ث‬‫ن‬‫ف‬‫ن‬‫ت‬
• Definition: An act of bringing up and spitting out sputum.
• Is sputum produced? In cough
• Looks like? Colour? Consistency?
• Yellow or green: usually purulent
• Odour? Foul smelling- Bronchiectasis
• Amount? Bronchiectasis: a cupful amount
• Asthma: small amount of thick jelly like sputum
Exam. of RS...Dr Sana Kauser (Pathology) 14
Haemoptysis‫ادلم‬‫ن‬
• Definition: Coughing up blood from the lungs or
bronchial tubes in the sputum. It can range from small
flecks of blood to a lot of blood.
• Amount?
• Fresh or altered blood
• D/D from hematemesis, bleeding from gums
• Whether associated with epistaxis or melena
• Suspected T.B., malignancy
Exam. of RS...Dr Sana Kauser (Pathology) 15
Breathlessness ‫سفنت‬‫رسع‬
• Definition: Shortness of breath is also known as dyspnea.
It is a feeling that one cannot breath enough air into the
lungs. It may be associated with tightness in the chest.
• Dyspnea on exertion or at rest?
• Episodic/ paroxysmal?....asthma
• Nocturnal? ……pulmonary oedema
• In sitting position or on lying down
Exam. of RS...Dr Sana Kauser (Pathology) 16
Paroxysmal dyspnoea
Whooping cough
Bronchiectasis
Bronchial asthma
Cardiac asthma
Exam. of RS...Dr Sana Kauser (Pathology) 17
Wheezing
• Definition: The shrill whistle or coarse rattle heard due to partial
or complete blockage in the airway.
• It could go away on its own, or it could be a sign of a serious
condition.
• Wheez- Present on examination or noticed sometime by any
individual
• Respiratory:
bronchitis
Asthma
Pneumonia
• Others
an allergic reaction, cold or allergies
Heart failure and more
D/D with
stridor
Rubbing/
gurgling sound-
pneumothorax
Exam. of RS...Dr Sana Kauser (Pathology)
18
Cont…
• Some wheezes can only be heard with a stethoscope, but
often they can be heard with the human ear.
• Wheezing is more obvious at the time of exhalation, but can
also be heard during inhalation.
• The tone of the wheeze can vary depending on which part of
the respiratory system is blocked or narrowed.
• Narrowing in the upper respiratory system may make for a
hoarser wheeze.
• Lower obstructions may have a more musical tone, similar to
a how a wind instrument like a clarinet might sound.
Exam. of RS...Dr Sana Kauser (Pathology) 19
Pain in the chest‫ادصلر‬‫وعج‬
• Chest pain-------site, duration, nature, relation with
respiration aggravating & releiving factors.
• Causes:
• Pleuritic pain- sharp, stabbing, aggravated in deep breath
or coughing………pleurisy
• Musculoskeletal
• Prolonged coughing
• Invasion of chest wall by lug tumour
• Pulmonary embolism
Exam. of RS...Dr Sana Kauser (Pathology) 20
2. GENERAL
EXAMINATION
‫ومعیم‬‫ااحتمن‬
Exam. of RS...Dr Sana Kauser (Pathology) 21
GENERAL EXAMINATION
• Physique/ Built
(wasting)
• Nourishment
• Anemia and pallor
• Jaundice
• Cyanosis
• Pigmrntation
• Clubbing
• Koilynochia
• Lymphadenopathy
• Pedal edema
• Vitals –
Pulse
BP
Temp
Respirations-
Rate
Regular
Type of Respiration
• Voice
• Breathlessness
• Clubbing of the
fingers
• Tobacco staining of
fingers
• Bruising
• Thinning of skin
• Venous pulsus
• Ptosis
• Swollen face
Exam. of RS...Dr Sana Kauser (Pathology) 22
FACE
Types of face
Exam. of RS...Dr Sana Kauser (Pathology)
24
Cont…
 Pink puffers (emphysema)
 Blue bloaters (chronic
bronchitis)
 Parotid enlargement (alcohol)
 Rashes
Exam. of RS...Dr Sana Kauser (Pathology)
25
MOUTH
• Breath (fetor hepaticus)
• Lips
• Angular stomatitis
• Cheilitis
• Ulceration
• Peutz-Jeghers syndrome
• Gums
• Gingivitis, bleeding
• Candida albicans
• Pigmentation
Exam. of RS...Dr Sana Kauser (Pathology) 26
Atrophic glossitis Thrush
Tongue
• Atrophic glossitis
• Leicoplakia
• Furring
Cont…
Exam. of RS...Dr Sana Kauser (Pathology) 27
• Conjuctival pallor
(anaemia)
• Sclera: jaundice
EYES
Exam. of RS...Dr Sana Kauser (Pathology) 28
 Cornea: Kaiser Fleischer’s
rings (Wilson’s disease)
 Xanthelasma (cholesterol
deposit, primary biliary
cirrhosis)
Exam. of RS...Dr Sana Kauser (Pathology) 29
Cont…
 Horner’s syndrome- ca. bronchus
 Chemosis
 Conjunctivitis
Exam. of RS...Dr Sana Kauser (Pathology)
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NECK
Enlarged Lymph nodes:
• TB
• Lymphoma
• Sarcoidosis
• Malignancy
Congested neck veins
Exam. of RS...Dr Sana Kauser (Pathology) 31
Exam. of RS...Dr Sana Kauser (Pathology)
32
SKIN
 Rashes:
Herpes zoster
Typhoid
Skin diseases
Allergic conditions
 Dilated veins---SVC
obstruction
 Scars:
Previous operation
Injury
Burns
Biopsies
 Pigmentation-
haemochromotosis
Exam. of RS...Dr Sana Kauser (Pathology) 33
Exam. of RS...Dr Sana Kauser (Pathology)
34
CYANOSIS
Central
Peripheral
Causes of central:
COPD
Resp. failure
Pulmonary fibrosis
Bronchial asthma
Congenital cyanotic heart disease (ASD, VSD, PDA)
Pulmonary embolism
Exam. of RS...Dr Sana Kauser (Pathology) 35
Cyanosis
Exam. of RS...Dr Sana Kauser (Pathology)
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OEDEMA
General:
• Right ventricular failure
• Cor pulmonale
• Renal failure
Local:
• Lymphatic obstruction
• Inflammation
Exam. of RS...Dr Sana Kauser (Pathology)
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HANDS
• Nails
• Clubbing
• Koilonychia
• Leuconychia
• Palmar erythema
• Dupuytren’s contractures
Exam. of RS...Dr Sana Kauser (Pathology) 38
Clubbing
 Bulbous enlargement of soft parts of the terminal phalanges with both
transverse and longitudinal curving of the nails.
 CA bronchus
 TB
 Empyema
 Abscess
 Fibrosing alveolitis
 Bronchiectasis
Exam. of RS...Dr Sana Kauser (Pathology)
39
Schamroth’s sign
Exam. of RS...Dr Sana Kauser (Pathology)
40
When the nails of two
normal fingers are
opposed each other,
there is a diamond
shaped gap.
In clubbing this gap
disappears known as
Schamroth’s sign
HANDS
Palmar erythema Dupuytren’s contractures
Exam. of RS...Dr Sana Kauser (Pathology) 41
HANDS
Peripheral
Cyanosis
Exam. of RS...Dr Sana Kauser (Pathology)
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ARMS
• Spider naevi (telangiectatic lesions)
• Bruising
• Wasting
• Scratch marks (chronic cholestasis)
Exam. of RS...Dr Sana Kauser (Pathology)
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PULSE
 Normal- 78/min
 Tachycardia- >120/min—Infections
---P.E
--B. asthma
--COPD exacerbation
 Bradycardia: Generally no underlying disease, fitness
 Collapsing pulse- Large volume bounding pulse (aortic regurgitation)
PULSES PARADOXUS
 Status Asthmaticus
 Massive pulmonary embolism
 Tension pneumothorax
 Cardiac temponade
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45
2. SYSTEMIC
EXAMINATION
‫اظنیم‬‫ااحتمن‬
Exam. of RS...Dr Sana Kauser (Pathology) 46
EXAMINATION OF
RESPIRATORY SYSTEM
INSPECTION
PALPATION
AUSCULTATION
PERCUSSION
Exam. of RS...Dr Sana Kauser (Pathology) 47
INSPECTION
‫ابرظنل‬‫ااحتمن‬
Exam. of RS...Dr Sana Kauser (Pathology) 48
Exam. of RS...Dr Sana Kauser (Pathology)
49
INSPECTION
• Upper respiratory tract (nose, oral cavity, larynx)
• Trachea
• Shape of chest
• Apex impules
• Engorged veins, pulsations
• Scars, sinuses, swellings, bulgings
Exam. of RS...Dr Sana Kauser (Pathology) 50
Cont…
• Drooping of shoulder
• Widening of intercostal spaces
• Indrawing of intercostal spaces, crowding of ribs
• Increased hollowness or fullness of supra and infra
clavicular fossae
• Mediastinum: Trails sign, apex impulse
Exam. of RS...Dr Sana Kauser (Pathology) 51
SHAPE OF THE CHEST
Normal: transverse diam> AP
A-P diameter
Pectus excavatum---funnel chest
Pectus carinatum---pigeon chest
Kyphoscoliosis
Exam. of RS...Dr Sana Kauser (Pathology) 52
Pigeon chest
Funnel chest
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Barrel chest
Kyphosis Scoliosis
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54
Respiratory rate and Rhythm
• Rate:
• Normal Respiratory Rate-{14-16/min}
• Hyperventilation-DKA, PE
• Hypoventilation-type 2 resp. failure
• Bradypnea: rate under 12: coma, medications, deep sleep
• Tachypnea: rate over 20: anxiety, heart or lung disease, pain
• Respiratory rhythm:
Chyne stokes breathing: Cyclical variation in the depth of respiration
with period of apnoea. drugs, CNS damage, stroke
Kussmaul: rapid, deep
Labored: metabolic acidosis
Exam. of RS...Dr Sana Kauser (Pathology) 55
Cont…
• Character:
Abdominal, thoracic, thoraco-abdominal, abdomino-thoracic
• Respiratory movements:
 Bilaterally equal
 Flail chest
Exam. of RS...Dr Sana Kauser (Pathology) 56
Deviated Trachea
Exam. of RS...Dr Sana Kauser (Pathology) 57
DILATED VEINS
SVC obstruction---Ca lung
Exam. of RS...Dr Sana Kauser (Pathology)
58
PALPATION
‫ابسمل‬‫ااحتمن‬
Exam. of RS...Dr Sana Kauser (Pathology) 59
PALPATION
• Tracheal position
• Apex beat
• Movements of chest
• Measurements—AP & transverse diameter,
• Chest-inspiration, expiration
• Hemi thorax measurement
• Palpation of inter costal spaces
• Vocal fremitus
• Tenderness, local rise of temp
Exam. of RS...Dr Sana Kauser (Pathology) 60
Tracheal position
4-5 cm of the upper trachea can be felt in the neck between the cricoid
cartilage and the sternal notch.
 Pushed –pneumothorax
-pleural effusion
 Pulled—fibrosis
--collapse
Exam. of RS...Dr Sana Kauser (Pathology)
61
Apex beat
• Lowermost & outermost point where cardiac impulse is
felt.
• Normally- 5th ICS within midclavicular line.
• Heaving apex: LVH (sustained throghout systole,
exaggerated )
• Tapping apex: mitral stenosis (loud first heart sound)
• Parasternal heave: left parasternal region, RV enlargement
62
Exam. of RS...Dr Sana Kauser (Pathology)
Movements of chest
 Chest expansion– normal up to 5 cm
-abnormal < 2 cm
• Movements of chest
 Use of accessory muscles- Status Asthmaticus
 Tenderness: Fractured ribs, metastasis , neuralgia
Exam. of RS...Dr Sana Kauser (Pathology) 63
Palpation of respiratory movements
Anterior, Apical, Posterior
Exam. of RS...Dr Sana Kauser (Pathology) 64
Palpation of inter costal spaces
Exam. of RS...Dr Sana Kauser (Pathology) 65
Tactile Vocal Fremitus
Vocal fremitus is a vibration transmitted through the body.
It refers to the assessment of the lungs by either the vibration intensity felt on the
chest wall (tactile fremitus) and/or heard by a stethoscope on the chest wall with
certain spoken words (vocal resonance).
Exam. of RS...Dr Sana Kauser (Pathology)
66
Exam. of RS...Dr Sana Kauser (Pathology)
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PERCUSSION
‫ابرقلع‬‫ااحتمن‬
Exam. of RS...Dr Sana Kauser (Pathology) 68
“
”
The percussion note loses its normal
resonance when ever aerated lung tissue is
separated from the chest wall by fluid or
pleural thickening .
OR
When lung tissue is separated from chest
wall by collapse or consolidation or
fibrosis
Exam. of RS...Dr Sana Kauser (Pathology) 69
PERCUSSION
Direct percussion
Over clavicles
Indirect percussion
Anterior
KRONIGS
ISTHMUS
Supra clavicular
Infra clavicular
Mammary
Infra mammary
Lateral
Axillary
Infra axillary
Posterior
Supra scapular
Inter scapular
Infra scapular area
Exam. of RS...Dr Sana Kauser (Pathology)
70
Cont…
Tidal percussion
Kronig isthmus
Traube’s space
S-shifting dullness
S –succusion splash
Skodaic resonance
Coin test above the fluid level
Liver dullness
Exam. of RS...Dr Sana Kauser (Pathology) 71
Exam. of RS...Dr Sana Kauser (Pathology)
72
Cont…
• Traube's (semilunar) space is an anatomic space of some clinical
importance. It is a crescent-shaped space, encompassed by the lower
edge of the left lung, the anterior border of the spleen, the left costal
margin and the inferior margin of the left lobe of the liver. Thus, its
surface markings are respectively the left sixth rib superiorly, the left
mid axillary line laterally, and the left costal margin inferiorly.
• A succussion splash, also known as a gastric splash, is
a sloshing sound heard through a stethoscope during sudden movement
of the patient on abdominal auscultation. It reflects the presence of gas
and fluid in an obstructed organ, as in gastric outlet obstruction.
• A coin test (or a bell metal resonance) is a medical diagnostic
test used to test for a punctured lung. A punctured lung can cause air
or fluid to leak into the pleural cavity, leading to, for
example, pneumothorax or hydrothorax.
Exam. of RS...Dr Sana Kauser (Pathology) 73
Cont…
• Kronig isthmus is a band of resonance representing
the apex of lung,[1] also it's described as the narrow strap-
like portion of the resonant field that extends over
the shoulder, that connect the larger areas of resonance
over the pulmonary apex in front and behind.[2
• Skodaic resonance - a peculiar, high-pitched sound, less
musical than that obtained over a cavity, elicited by
percussion just above the level of a pleuritic effusion.
• Shifting dullness and fluid thrill (wave) are clinical signs
that confirm ascites. Free fluid will flow to the dependent
part of the abdominal cavity, while the gut filled with air
will float in the middle. If the child is supine, the fluid
collects posteriorly and in the flanks.
Exam. of RS...Dr Sana Kauser (Pathology)
74
Cont…
• Liver dullness: The purpose of liver percussion is to
measure the liver size. Starting in the midclavicular line at
about the 3rd intercostal space, lightly percuss and move
down. Percuss inferiorly until dullness denotes the liver's
upper border (usually at 5th intercostal space in MCL).
Exam. of RS...Dr Sana Kauser (Pathology) 75
Areas of Percussion
Exam. of RS...Dr Sana Kauser (Pathology) 76
AUSCULTATION
‫ع‬‫م‬‫س‬‫ل‬
‫اب‬‫ااحتمن‬
Exam. of RS...Dr Sana Kauser (Pathology) 77
BREATH SOUNDS
• Breath sounds come from the
lungs when you breathe in and
out. A person can hear these
sounds using a stethoscope or
simply when breathing.
• A typical breath sound is similar
to the sound of air.
 Check for Intensity
 Character:
Vesicular-
https://www.google.com/search?q=vesicular+sound&rlz=1C1LOQA
Bronchial-
https://www.google.com/search?q=bronchial+spund&rlz
Vesicular
Normal
Insp. twice
that of
expiration
No pause
Bronchial
Inspiration is
shorter than
expiration
Gap between
insp. and
exp.
Exam. of RS...Dr Sana Kauser (Pathology)
78
ADDED SOUNDS
• However, it may include some irregular breath sounds.
 Added/ adventitious sounds:
Exam. of RS...Dr Sana Kauser (Pathology) 79
Cont…
• Rhonchi: https://www.google.com/search?q=rhonchi+sound&rlz
Low pitched breath sounds that are similar to snoring.
These sounds occur when air tries to pass through bronchial
tubes that contain fluid or mucus.
Wheezing: https://www.google.com/search?q=wheezing+sound&rlz
• Wheezing, is a high pitched whistling sound that occurs
due to the narrowing of the bronchial tubes
• This sound occurs when the bronchial tubes become
inflamed and narrowed.
 Wheezes or rhonchi---COPD
--bronchial asthma
Exam. of RS...Dr Sana Kauser (Pathology) 80
Cont…
• Crackles/Crepitations:
https://www.youtube.com/watch?v=z2Ra9UxndI0
https://www.google.com/search?q=crackles+sound&rlz=1
Crackles, are high pitched breath sounds that are similar to
popping or snapping.
These sounds occur if the small air sacs in the lungs fill with
fluid and there’s air movement in the sacs, such as when
you’re breathing. The air sacs fill with fluid when a person
has pneumonia or heart failure.
Fine
• Heart failure
• Fibrosing alveolitis
Coarse
• Bronchiectasis
• Infections
Exam. of RS...Dr Sana Kauser (Pathology)
81
Cont…
• Stridor: https://www.google.com/search?q=stridor+sound&rl
A harsh, vibratory sound that occurs due to the narrowing
of the upper airway, heard most prominently in inhalation.
• Pleural rub: https://youtu.be/xxVvxdoAUPk
A Pleural friction rub or Pleural rub, is an audible raspy
breathing sound. It is a medical sign present in some patients
with pleurisy and other conditions affecting the chest cavity.
It can be noticed by listening to the internal sounds of the
body, usually using a stethoscope on the lungs.
These are the squeaking or grating sounds of the pleural
linings rubbing together. It is best described as the sound
made by treading on fresh snow.
Pleural rubs are common in pneumonia, pulmonary
embolism, and pleurisy.
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83
VOCAL RESONANCE
• Definition: Vocal resonance is an assessment of the
density of lung tissue, performed by auscultating the chest
and asking the patient to speak. Increased vocal resonance
suggests increased density, while reduced vocal resonance
suggests an increase in the amount of air present.
• How to Assess:
Auscultate the patient's chest, starting at the top and moving
to the bottom, as they perform the following:
Bronchophony - ask the patient to say ' blue balloons'.
Whispered pectoriloquy - ask the patient to whisper 'blue
balloons'.
Egophony - ask the patient to say 'eeee'.
Exam. of RS...Dr Sana Kauser (Pathology)
84
Impaired vocal resonance
• Increased Vocal Resonance
• Increased resonance of vocal
sounds on auscultation of the chest.
• Significance
• Occurs due to increased density
within the lung parenchyma.
• Causes of Increased Vocal
Resonance
• Pneumonia
• Atelectasis
• Lung cancer
• Reduced Vocal Resonance
• Reduced resonance of vocal sounds
on auscultation of the chest.
• Significance
• Occurs due to reduced density
within the lung parenchyma.
• Causes of Reduced Vocal
Resonance
• Pneumothorax
• Emphysema
• Haemothorax
• Pleural effusion
• Obesity
Exam. of RS...Dr Sana Kauser (Pathology) 85
Bronchophony
• Bronchophony is a type of pectoriloquy, in which voice
transmission through lung structures is heard with a higher
resonance. In particular, bronchophony refers to an
atypical increase in the intensity and clarity of the
individual's spoken voice heard when auscultating the
lungs with a stethoscope.
• Why Blue Balloons?
• Tactile fremitus was first described by a German physician who called
for the patient to say "neunundneunzig" (ninety-nine). "Blue Balloons"
is an English phrase that closely resembles the sound and vibration
emitted from the lungs when saying "neunundneunzig" (a low
frequency 'diphthong' phrase).
Exam. of RS...Dr Sana Kauser (Pathology) 86
Egophony
Egophony (also known as “E” to “A” change) is an
auscultatory finding due to a change in the quality of the
voice.
A solid (consolidated), fluid-filled, or compressed lung
decreases the amplitude and only allows select frequencies
to pass through. This changes the sound of the vowel “E”
to "A."
Method:
• ask the patient to say “ ee “ continuously
• you should hear muffled ‘’ee ‘’
• if you hear an ‘’ ay ‘’ then it is egophony
Exam. of RS...Dr Sana Kauser (Pathology)
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Whispering pectroloquy
Pectoriloquy is the increased resonance of the voice through
the lung structures, so that it is clearly comprehensible using
a stethoscope on the chest. It usually indicates consolidation
of the underlying lung parenchyma.
Method:
• Ask the patient to whisper 99
• you should hear only faint sounds or nothing
• Consolidation- If you hear the sound clearly then this is
referred as whispering pectroloquy.
Exam. of RS...Dr Sana Kauser (Pathology) 88
Bronchophony vs Egophony vs Pectoriloquy
Bronchophony:
Vocal resonance
increased in
intensity and
clearness.
Pectoriloquy:
Exaggerated
bronchophony
with articulated
overtones-
syllabic speech.
Whispered
pectoriloquy:
sounds heard
with whispered
voice.
Egophony:
A variety of
bronchophony
having a nasal
or bleating
quality.
Exam. of RS...Dr Sana Kauser (Pathology)
89
THANK
YOU
Exam. of RS...Dr Sana Kauser (Pathology) 90

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Respiratory System Exam....Dr Sana Kauser Patho.pdf

  • 2. Dr Sana Kauser Ateeque Ahmed Assistant Professor Dept. of Mahiyatul Amraz Al-Ameen Unani Medical College & Hospital, Malegaon Exam. of RS...Dr Sana Kauser (Pathology) 2
  • 3. Contents ▰ History taking  Bio data of the patient  Chief/ Presenting complaints  History of presenting complaints  Cardinal symptoms ▰ Examination of respiratory System o Inspection o Palpation o Percussion o Auscultation Exam. of RS...Dr Sana Kauser (Pathology) 3
  • 4. 4 Structures present in the chest cavity • Diseases of the RS accounts for third of deaths • Major cause of patients visit to the doctor • An important part of systemic examination Introduction Exam. of RS...Dr Sana Kauser (Pathology)
  • 5. 1. HISTORY TAKING ‫رمضی‬‫روداد‬ Exam. of RS...Dr Sana Kauser (Pathology) 5
  • 6. “ ” Basically with history, from each point you ask the patient and each answer you get from the patient, you understood that yes, these are probable diagnosis . 6
  • 7. Bio data of the patient Name Age Sex Occupation Address Religion Marital status 7 Exam. of RS...Dr Sana Kauser (Pathology)
  • 8. Presenting complaints RESPIRATORY SYSTEM • History of presenting complaints • Chronological order (complaints with duration) • Pain (SOCRATES) • Cough: Dry or productive • If productive: Quantity, Color, Nature, Odor, Haemoptysis, relation to posture, diurnal variation. • Breathlessness: duration, grade, postural variation, diurnal variation, seasonal variation, • History of wheezing • History of Orthopnea 8 Exam. of RS...Dr Sana Kauser (Pathology)
  • 9. Others • History of past illness: Hypertension, DM, TB, HIV, Exathematous fevers. • Personal history: food/appetite, B/B, sleep addiction-smoking, alcohol, drug addictions • Family history • Menstrual and obstetric history • Treatment history (anaphylaxis, urticaria) • H/O Fever • H/o allergies, swelling of feet, palpitations, seizures, • Surgery under general anesthesia 9 Exam. of RS...Dr Sana Kauser (Pathology)
  • 10. Cardinal symptoms The primary or major symptom by which a diagnosis is made • Cough • Expectoration/ Sputum • Haemoptysis • Breathlessness/ dyspnoea • Wheezing • Pain in the chest Exam. of RS...Dr Sana Kauser (Pathology) 10
  • 11. Cough ‫اھکیسن‬ Definition: A sudden expulsion of air through the large breathing passages that can help clear them of fluids, irritants, foreign particles and microbes. • Acute/ short lived or chronic • Dry or productive • Episodic? Time? • Related to any posture • Aggravated by Allergens? Pollens? Cold air? Acute (lasting <3 weeks) Recent infections (viral/ bacterial) Chronic (lasting > 8 weeks) Should be Sent for CXR, spirometry Exam. of RS...Dr Sana Kauser (Pathology) 11
  • 12. Causes of cough Causes Examples Respiratory Viral or bacterial infections Bronchospasm COPD Asthma Aspiration Brochiolitis (infection and inflam. of bronchioles in children and infants) Malignancy Parenchymal disease e.g. ILD (progressive scarring) Cystic fibrosis (inherited, affect mucus and sweat producing cell, thick & sticky fluids, plug) Upper airways diseases Post nasal drip Sinusitis Inhaled foreign bodies Tonsillar enlargement Cardiovascular diseases LVF, Mitral stenosis Gastro-oesophageal disease GORD Drugs and irritation ACE inhibitors (prils-antihypertensive), cigarette smoking Exam. of RS...Dr Sana Kauser (Pathology) 12
  • 14. Sputum/ Expectoration‫ث‬‫ن‬‫ف‬‫ن‬‫ت‬ • Definition: An act of bringing up and spitting out sputum. • Is sputum produced? In cough • Looks like? Colour? Consistency? • Yellow or green: usually purulent • Odour? Foul smelling- Bronchiectasis • Amount? Bronchiectasis: a cupful amount • Asthma: small amount of thick jelly like sputum Exam. of RS...Dr Sana Kauser (Pathology) 14
  • 15. Haemoptysis‫ادلم‬‫ن‬ • Definition: Coughing up blood from the lungs or bronchial tubes in the sputum. It can range from small flecks of blood to a lot of blood. • Amount? • Fresh or altered blood • D/D from hematemesis, bleeding from gums • Whether associated with epistaxis or melena • Suspected T.B., malignancy Exam. of RS...Dr Sana Kauser (Pathology) 15
  • 16. Breathlessness ‫سفنت‬‫رسع‬ • Definition: Shortness of breath is also known as dyspnea. It is a feeling that one cannot breath enough air into the lungs. It may be associated with tightness in the chest. • Dyspnea on exertion or at rest? • Episodic/ paroxysmal?....asthma • Nocturnal? ……pulmonary oedema • In sitting position or on lying down Exam. of RS...Dr Sana Kauser (Pathology) 16
  • 17. Paroxysmal dyspnoea Whooping cough Bronchiectasis Bronchial asthma Cardiac asthma Exam. of RS...Dr Sana Kauser (Pathology) 17
  • 18. Wheezing • Definition: The shrill whistle or coarse rattle heard due to partial or complete blockage in the airway. • It could go away on its own, or it could be a sign of a serious condition. • Wheez- Present on examination or noticed sometime by any individual • Respiratory: bronchitis Asthma Pneumonia • Others an allergic reaction, cold or allergies Heart failure and more D/D with stridor Rubbing/ gurgling sound- pneumothorax Exam. of RS...Dr Sana Kauser (Pathology) 18
  • 19. Cont… • Some wheezes can only be heard with a stethoscope, but often they can be heard with the human ear. • Wheezing is more obvious at the time of exhalation, but can also be heard during inhalation. • The tone of the wheeze can vary depending on which part of the respiratory system is blocked or narrowed. • Narrowing in the upper respiratory system may make for a hoarser wheeze. • Lower obstructions may have a more musical tone, similar to a how a wind instrument like a clarinet might sound. Exam. of RS...Dr Sana Kauser (Pathology) 19
  • 20. Pain in the chest‫ادصلر‬‫وعج‬ • Chest pain-------site, duration, nature, relation with respiration aggravating & releiving factors. • Causes: • Pleuritic pain- sharp, stabbing, aggravated in deep breath or coughing………pleurisy • Musculoskeletal • Prolonged coughing • Invasion of chest wall by lug tumour • Pulmonary embolism Exam. of RS...Dr Sana Kauser (Pathology) 20
  • 22. GENERAL EXAMINATION • Physique/ Built (wasting) • Nourishment • Anemia and pallor • Jaundice • Cyanosis • Pigmrntation • Clubbing • Koilynochia • Lymphadenopathy • Pedal edema • Vitals – Pulse BP Temp Respirations- Rate Regular Type of Respiration • Voice • Breathlessness • Clubbing of the fingers • Tobacco staining of fingers • Bruising • Thinning of skin • Venous pulsus • Ptosis • Swollen face Exam. of RS...Dr Sana Kauser (Pathology) 22
  • 23. FACE Types of face Exam. of RS...Dr Sana Kauser (Pathology) 24
  • 24. Cont…  Pink puffers (emphysema)  Blue bloaters (chronic bronchitis)  Parotid enlargement (alcohol)  Rashes Exam. of RS...Dr Sana Kauser (Pathology) 25
  • 25. MOUTH • Breath (fetor hepaticus) • Lips • Angular stomatitis • Cheilitis • Ulceration • Peutz-Jeghers syndrome • Gums • Gingivitis, bleeding • Candida albicans • Pigmentation Exam. of RS...Dr Sana Kauser (Pathology) 26
  • 26. Atrophic glossitis Thrush Tongue • Atrophic glossitis • Leicoplakia • Furring Cont… Exam. of RS...Dr Sana Kauser (Pathology) 27
  • 27. • Conjuctival pallor (anaemia) • Sclera: jaundice EYES Exam. of RS...Dr Sana Kauser (Pathology) 28
  • 28.  Cornea: Kaiser Fleischer’s rings (Wilson’s disease)  Xanthelasma (cholesterol deposit, primary biliary cirrhosis) Exam. of RS...Dr Sana Kauser (Pathology) 29
  • 29. Cont…  Horner’s syndrome- ca. bronchus  Chemosis  Conjunctivitis Exam. of RS...Dr Sana Kauser (Pathology) 30
  • 30. NECK Enlarged Lymph nodes: • TB • Lymphoma • Sarcoidosis • Malignancy Congested neck veins Exam. of RS...Dr Sana Kauser (Pathology) 31
  • 31. Exam. of RS...Dr Sana Kauser (Pathology) 32
  • 32. SKIN  Rashes: Herpes zoster Typhoid Skin diseases Allergic conditions  Dilated veins---SVC obstruction  Scars: Previous operation Injury Burns Biopsies  Pigmentation- haemochromotosis Exam. of RS...Dr Sana Kauser (Pathology) 33
  • 33. Exam. of RS...Dr Sana Kauser (Pathology) 34
  • 34. CYANOSIS Central Peripheral Causes of central: COPD Resp. failure Pulmonary fibrosis Bronchial asthma Congenital cyanotic heart disease (ASD, VSD, PDA) Pulmonary embolism Exam. of RS...Dr Sana Kauser (Pathology) 35
  • 35. Cyanosis Exam. of RS...Dr Sana Kauser (Pathology) 36
  • 36. OEDEMA General: • Right ventricular failure • Cor pulmonale • Renal failure Local: • Lymphatic obstruction • Inflammation Exam. of RS...Dr Sana Kauser (Pathology) 37
  • 37. HANDS • Nails • Clubbing • Koilonychia • Leuconychia • Palmar erythema • Dupuytren’s contractures Exam. of RS...Dr Sana Kauser (Pathology) 38
  • 38. Clubbing  Bulbous enlargement of soft parts of the terminal phalanges with both transverse and longitudinal curving of the nails.  CA bronchus  TB  Empyema  Abscess  Fibrosing alveolitis  Bronchiectasis Exam. of RS...Dr Sana Kauser (Pathology) 39
  • 39. Schamroth’s sign Exam. of RS...Dr Sana Kauser (Pathology) 40 When the nails of two normal fingers are opposed each other, there is a diamond shaped gap. In clubbing this gap disappears known as Schamroth’s sign
  • 40. HANDS Palmar erythema Dupuytren’s contractures Exam. of RS...Dr Sana Kauser (Pathology) 41
  • 41. HANDS Peripheral Cyanosis Exam. of RS...Dr Sana Kauser (Pathology) 42
  • 42. ARMS • Spider naevi (telangiectatic lesions) • Bruising • Wasting • Scratch marks (chronic cholestasis) Exam. of RS...Dr Sana Kauser (Pathology) 43
  • 43. PULSE  Normal- 78/min  Tachycardia- >120/min—Infections ---P.E --B. asthma --COPD exacerbation  Bradycardia: Generally no underlying disease, fitness  Collapsing pulse- Large volume bounding pulse (aortic regurgitation) PULSES PARADOXUS  Status Asthmaticus  Massive pulmonary embolism  Tension pneumothorax  Cardiac temponade Exam. of RS...Dr Sana Kauser (Pathology) 45
  • 47. Exam. of RS...Dr Sana Kauser (Pathology) 49
  • 48. INSPECTION • Upper respiratory tract (nose, oral cavity, larynx) • Trachea • Shape of chest • Apex impules • Engorged veins, pulsations • Scars, sinuses, swellings, bulgings Exam. of RS...Dr Sana Kauser (Pathology) 50
  • 49. Cont… • Drooping of shoulder • Widening of intercostal spaces • Indrawing of intercostal spaces, crowding of ribs • Increased hollowness or fullness of supra and infra clavicular fossae • Mediastinum: Trails sign, apex impulse Exam. of RS...Dr Sana Kauser (Pathology) 51
  • 50. SHAPE OF THE CHEST Normal: transverse diam> AP A-P diameter Pectus excavatum---funnel chest Pectus carinatum---pigeon chest Kyphoscoliosis Exam. of RS...Dr Sana Kauser (Pathology) 52
  • 51. Pigeon chest Funnel chest Exam. of RS...Dr Sana Kauser (Pathology) 53 Barrel chest
  • 52. Kyphosis Scoliosis Exam. of RS...Dr Sana Kauser (Pathology) 54
  • 53. Respiratory rate and Rhythm • Rate: • Normal Respiratory Rate-{14-16/min} • Hyperventilation-DKA, PE • Hypoventilation-type 2 resp. failure • Bradypnea: rate under 12: coma, medications, deep sleep • Tachypnea: rate over 20: anxiety, heart or lung disease, pain • Respiratory rhythm: Chyne stokes breathing: Cyclical variation in the depth of respiration with period of apnoea. drugs, CNS damage, stroke Kussmaul: rapid, deep Labored: metabolic acidosis Exam. of RS...Dr Sana Kauser (Pathology) 55
  • 54. Cont… • Character: Abdominal, thoracic, thoraco-abdominal, abdomino-thoracic • Respiratory movements:  Bilaterally equal  Flail chest Exam. of RS...Dr Sana Kauser (Pathology) 56
  • 55. Deviated Trachea Exam. of RS...Dr Sana Kauser (Pathology) 57
  • 56. DILATED VEINS SVC obstruction---Ca lung Exam. of RS...Dr Sana Kauser (Pathology) 58
  • 58. PALPATION • Tracheal position • Apex beat • Movements of chest • Measurements—AP & transverse diameter, • Chest-inspiration, expiration • Hemi thorax measurement • Palpation of inter costal spaces • Vocal fremitus • Tenderness, local rise of temp Exam. of RS...Dr Sana Kauser (Pathology) 60
  • 59. Tracheal position 4-5 cm of the upper trachea can be felt in the neck between the cricoid cartilage and the sternal notch.  Pushed –pneumothorax -pleural effusion  Pulled—fibrosis --collapse Exam. of RS...Dr Sana Kauser (Pathology) 61
  • 60. Apex beat • Lowermost & outermost point where cardiac impulse is felt. • Normally- 5th ICS within midclavicular line. • Heaving apex: LVH (sustained throghout systole, exaggerated ) • Tapping apex: mitral stenosis (loud first heart sound) • Parasternal heave: left parasternal region, RV enlargement 62 Exam. of RS...Dr Sana Kauser (Pathology)
  • 61. Movements of chest  Chest expansion– normal up to 5 cm -abnormal < 2 cm • Movements of chest  Use of accessory muscles- Status Asthmaticus  Tenderness: Fractured ribs, metastasis , neuralgia Exam. of RS...Dr Sana Kauser (Pathology) 63
  • 62. Palpation of respiratory movements Anterior, Apical, Posterior Exam. of RS...Dr Sana Kauser (Pathology) 64
  • 63. Palpation of inter costal spaces Exam. of RS...Dr Sana Kauser (Pathology) 65
  • 64. Tactile Vocal Fremitus Vocal fremitus is a vibration transmitted through the body. It refers to the assessment of the lungs by either the vibration intensity felt on the chest wall (tactile fremitus) and/or heard by a stethoscope on the chest wall with certain spoken words (vocal resonance). Exam. of RS...Dr Sana Kauser (Pathology) 66
  • 65. Exam. of RS...Dr Sana Kauser (Pathology) 67
  • 67. “ ” The percussion note loses its normal resonance when ever aerated lung tissue is separated from the chest wall by fluid or pleural thickening . OR When lung tissue is separated from chest wall by collapse or consolidation or fibrosis Exam. of RS...Dr Sana Kauser (Pathology) 69
  • 68. PERCUSSION Direct percussion Over clavicles Indirect percussion Anterior KRONIGS ISTHMUS Supra clavicular Infra clavicular Mammary Infra mammary Lateral Axillary Infra axillary Posterior Supra scapular Inter scapular Infra scapular area Exam. of RS...Dr Sana Kauser (Pathology) 70
  • 69. Cont… Tidal percussion Kronig isthmus Traube’s space S-shifting dullness S –succusion splash Skodaic resonance Coin test above the fluid level Liver dullness Exam. of RS...Dr Sana Kauser (Pathology) 71
  • 70. Exam. of RS...Dr Sana Kauser (Pathology) 72
  • 71. Cont… • Traube's (semilunar) space is an anatomic space of some clinical importance. It is a crescent-shaped space, encompassed by the lower edge of the left lung, the anterior border of the spleen, the left costal margin and the inferior margin of the left lobe of the liver. Thus, its surface markings are respectively the left sixth rib superiorly, the left mid axillary line laterally, and the left costal margin inferiorly. • A succussion splash, also known as a gastric splash, is a sloshing sound heard through a stethoscope during sudden movement of the patient on abdominal auscultation. It reflects the presence of gas and fluid in an obstructed organ, as in gastric outlet obstruction. • A coin test (or a bell metal resonance) is a medical diagnostic test used to test for a punctured lung. A punctured lung can cause air or fluid to leak into the pleural cavity, leading to, for example, pneumothorax or hydrothorax. Exam. of RS...Dr Sana Kauser (Pathology) 73
  • 72. Cont… • Kronig isthmus is a band of resonance representing the apex of lung,[1] also it's described as the narrow strap- like portion of the resonant field that extends over the shoulder, that connect the larger areas of resonance over the pulmonary apex in front and behind.[2 • Skodaic resonance - a peculiar, high-pitched sound, less musical than that obtained over a cavity, elicited by percussion just above the level of a pleuritic effusion. • Shifting dullness and fluid thrill (wave) are clinical signs that confirm ascites. Free fluid will flow to the dependent part of the abdominal cavity, while the gut filled with air will float in the middle. If the child is supine, the fluid collects posteriorly and in the flanks. Exam. of RS...Dr Sana Kauser (Pathology) 74
  • 73. Cont… • Liver dullness: The purpose of liver percussion is to measure the liver size. Starting in the midclavicular line at about the 3rd intercostal space, lightly percuss and move down. Percuss inferiorly until dullness denotes the liver's upper border (usually at 5th intercostal space in MCL). Exam. of RS...Dr Sana Kauser (Pathology) 75
  • 74. Areas of Percussion Exam. of RS...Dr Sana Kauser (Pathology) 76
  • 76. BREATH SOUNDS • Breath sounds come from the lungs when you breathe in and out. A person can hear these sounds using a stethoscope or simply when breathing. • A typical breath sound is similar to the sound of air.  Check for Intensity  Character: Vesicular- https://www.google.com/search?q=vesicular+sound&rlz=1C1LOQA Bronchial- https://www.google.com/search?q=bronchial+spund&rlz Vesicular Normal Insp. twice that of expiration No pause Bronchial Inspiration is shorter than expiration Gap between insp. and exp. Exam. of RS...Dr Sana Kauser (Pathology) 78
  • 77. ADDED SOUNDS • However, it may include some irregular breath sounds.  Added/ adventitious sounds: Exam. of RS...Dr Sana Kauser (Pathology) 79
  • 78. Cont… • Rhonchi: https://www.google.com/search?q=rhonchi+sound&rlz Low pitched breath sounds that are similar to snoring. These sounds occur when air tries to pass through bronchial tubes that contain fluid or mucus. Wheezing: https://www.google.com/search?q=wheezing+sound&rlz • Wheezing, is a high pitched whistling sound that occurs due to the narrowing of the bronchial tubes • This sound occurs when the bronchial tubes become inflamed and narrowed.  Wheezes or rhonchi---COPD --bronchial asthma Exam. of RS...Dr Sana Kauser (Pathology) 80
  • 79. Cont… • Crackles/Crepitations: https://www.youtube.com/watch?v=z2Ra9UxndI0 https://www.google.com/search?q=crackles+sound&rlz=1 Crackles, are high pitched breath sounds that are similar to popping or snapping. These sounds occur if the small air sacs in the lungs fill with fluid and there’s air movement in the sacs, such as when you’re breathing. The air sacs fill with fluid when a person has pneumonia or heart failure. Fine • Heart failure • Fibrosing alveolitis Coarse • Bronchiectasis • Infections Exam. of RS...Dr Sana Kauser (Pathology) 81
  • 80. Cont… • Stridor: https://www.google.com/search?q=stridor+sound&rl A harsh, vibratory sound that occurs due to the narrowing of the upper airway, heard most prominently in inhalation. • Pleural rub: https://youtu.be/xxVvxdoAUPk A Pleural friction rub or Pleural rub, is an audible raspy breathing sound. It is a medical sign present in some patients with pleurisy and other conditions affecting the chest cavity. It can be noticed by listening to the internal sounds of the body, usually using a stethoscope on the lungs. These are the squeaking or grating sounds of the pleural linings rubbing together. It is best described as the sound made by treading on fresh snow. Pleural rubs are common in pneumonia, pulmonary embolism, and pleurisy. Exam. of RS...Dr Sana Kauser (Pathology) 82
  • 81. Exam. of RS...Dr Sana Kauser (Pathology) 83
  • 82. VOCAL RESONANCE • Definition: Vocal resonance is an assessment of the density of lung tissue, performed by auscultating the chest and asking the patient to speak. Increased vocal resonance suggests increased density, while reduced vocal resonance suggests an increase in the amount of air present. • How to Assess: Auscultate the patient's chest, starting at the top and moving to the bottom, as they perform the following: Bronchophony - ask the patient to say ' blue balloons'. Whispered pectoriloquy - ask the patient to whisper 'blue balloons'. Egophony - ask the patient to say 'eeee'. Exam. of RS...Dr Sana Kauser (Pathology) 84
  • 83. Impaired vocal resonance • Increased Vocal Resonance • Increased resonance of vocal sounds on auscultation of the chest. • Significance • Occurs due to increased density within the lung parenchyma. • Causes of Increased Vocal Resonance • Pneumonia • Atelectasis • Lung cancer • Reduced Vocal Resonance • Reduced resonance of vocal sounds on auscultation of the chest. • Significance • Occurs due to reduced density within the lung parenchyma. • Causes of Reduced Vocal Resonance • Pneumothorax • Emphysema • Haemothorax • Pleural effusion • Obesity Exam. of RS...Dr Sana Kauser (Pathology) 85
  • 84. Bronchophony • Bronchophony is a type of pectoriloquy, in which voice transmission through lung structures is heard with a higher resonance. In particular, bronchophony refers to an atypical increase in the intensity and clarity of the individual's spoken voice heard when auscultating the lungs with a stethoscope. • Why Blue Balloons? • Tactile fremitus was first described by a German physician who called for the patient to say "neunundneunzig" (ninety-nine). "Blue Balloons" is an English phrase that closely resembles the sound and vibration emitted from the lungs when saying "neunundneunzig" (a low frequency 'diphthong' phrase). Exam. of RS...Dr Sana Kauser (Pathology) 86
  • 85. Egophony Egophony (also known as “E” to “A” change) is an auscultatory finding due to a change in the quality of the voice. A solid (consolidated), fluid-filled, or compressed lung decreases the amplitude and only allows select frequencies to pass through. This changes the sound of the vowel “E” to "A." Method: • ask the patient to say “ ee “ continuously • you should hear muffled ‘’ee ‘’ • if you hear an ‘’ ay ‘’ then it is egophony Exam. of RS...Dr Sana Kauser (Pathology) 87
  • 86. Whispering pectroloquy Pectoriloquy is the increased resonance of the voice through the lung structures, so that it is clearly comprehensible using a stethoscope on the chest. It usually indicates consolidation of the underlying lung parenchyma. Method: • Ask the patient to whisper 99 • you should hear only faint sounds or nothing • Consolidation- If you hear the sound clearly then this is referred as whispering pectroloquy. Exam. of RS...Dr Sana Kauser (Pathology) 88
  • 87. Bronchophony vs Egophony vs Pectoriloquy Bronchophony: Vocal resonance increased in intensity and clearness. Pectoriloquy: Exaggerated bronchophony with articulated overtones- syllabic speech. Whispered pectoriloquy: sounds heard with whispered voice. Egophony: A variety of bronchophony having a nasal or bleating quality. Exam. of RS...Dr Sana Kauser (Pathology) 89
  • 88. THANK YOU Exam. of RS...Dr Sana Kauser (Pathology) 90