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Navid Manafi
Medical student
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Navid Manafi
Iran University of medical sciences
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Navid Manafi
Iran University of medical sciences
Ronald A. Squires , MD
Professor,Department of
Surgery,University of Oklahoma
Health Sciences Center,Oklahoma
city,Oklahoma
3
Navid Manafi
Iran University of medical sciences
Russell G. Postier, MD
John A. Schilling Professor and
Chairman,Department of Surgery,University of
Oklahoma Health sciences Center,Oklahoma
City,Oklahoma
4
Navid Manafi
Iran University of medical sciences
5
Navid Manafi
Iran University of medical sciences
Alex Nagle , MD, FACS
Northwestern University Feinberg School of
Medicine
Chicago,IL
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Navid Manafi
Iran University of medical sciences
Dr. Zachary Cope
English surgeon
1921 until 1971
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Navid Manafi
Iran University of medical sciences
HISTORY
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Navid Manafi
Iran University of medical sciences
DEFINITION
• Sabiston :
Signs & symptoms of abdominal pain &
tenderness,a clinical presentation that
often requires emergency surgical
therapy
• ACS Surgery :
Previously undiagnosed pain that arises
suddenly & is of less than 48 hour
duration
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Navid Manafi
Iran University of medical sciences
• younger : appendicitis
older :biliary disease , bowel obstruction
intestinal ischemia & Infarction ,
diverticulitis
• surgical dd. A/W acute abdomen :
1-Infection
2-Obstruction
3-Ischemia
4- Perforation
W/O : Hx , Ph/E , labs , Imaging
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Navid Manafi
Iran University of medical sciences
Surgical Acute Abdominal Conditions
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Navid Manafi
Iran University of medical sciences
Surgical Acute Abdominal Conditions
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Navid Manafi
Iran University of medical sciences
Abdominal Pain
1-Visceral (vague , mostly midline
(epigastrium ,periumbilical , hypogastrium)
usually from distention of a hollow viscus
2-Parietal (Sharper & better localized)
Sensory innervation of the viscera
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Navid Manafi
Iran University of medical sciences
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Navid Manafi
Iran University of medical sciences
Out pouching of
fluid
from peritoneal
membrane
Peritoneum:
Blood flow
permeability
formation of fibrinous exudate on
its surface
Bowel : local or generalized paralysis
Adherence between bowel & omentum
or abdominal wall
& help localize inflammation
Abscess :
sharply localized pain
+
normal bowel sounds & GI function
Diffuse process(perforated duodenal ulcer):
generalized abdominal pain
+
quiet abdomen
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Navid Manafi
Iran University of medical sciences
Entire abdominal cavity or part of visceral or parietal peritoneum
sever tenderness on palpation +/- rebound tenderness & guarding
causes infections e.g. Gram -ve bacteria or anaerobes
noninfectious e.g pancreatitis
Primary peritonitis in children (esp by Pneumococcus or Hemolytic Strep spp.)
Adults with ESRD on peritoneal dialysis Gram -ve cocci
adults with ascites & cirrhosis primary peritonitis esp E.Coli & klebsiella
PERITONITIS
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Navid Manafi
Iran University of medical sciences
Pain shown with finger (parietal innervation) peritoneal inflammation
……………….. palm of hand (visceral innervation) bowel or solid organ disease
sudden onset of excruciating pain intestinal perforation
arterial embolization with ischemia
biliary colic
Pain that develops & worsens over several hh. bowel obstruction
(progressive inflammation or infection) colitis
cholecystitis
Intermittent episodes of pain (colicky pain ) bowel obstruction
biliary colic from cystic duct obstruction
Genitourinary obstruction
HISTORY TAKING PEARLS
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Navid Manafi
Iran University of medical sciences
Small bowel pain periumbilical
colon pain between umbilicus & pubic symphysis
liver pain to shoulder is via C3 - C5 n. roots
Genitourinary pain commonly radiates
Flank (Splanchnic nn. of T11-L1)
Scrotum or Labia (Hypogastric plexus of S2-S4)
pain of Bowel obstruction , biliary colic,pancreatitis
, diverticulitis , bowel perforation
pain of non perforated PUD or gastritis
HISTORY TAKING PEARLS
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Navid Manafi
Iran University of medical sciences
Patients with peritoneal inflammation will avoid any
activity that stretches or jostles the abdomen
pain with sudden body movement
pain when knees flexed
Vomiting may occur because of severe abdominal pain of any
cause or as a result of mechanical bowel obstruction or ileum
HISTORY TAKING PEARLS
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Navid Manafi
Iran University of medical sciences
Many conditions : Vomiting severe abdominal pain
Acute surgical abdomen : Severe pain Vomiting
(via medullary efferent fibers)
Complete obstruction subsequent bowel ischemia
or perforation caused by massive distention that can occur
Infectious enteritis
IBD
Parasitic contamination
Colonic ischemia
A/W
Bloody
diarrhea
Diarrhea in
acute abdomen
HISTORY TAKING PEARLS
Lower abdominal pain
in a young lady
EP ,
PID ,
Mittelschmerz ,
Severe endometriosis 20
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Iran University of medical sciences
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High dose Narcotic Obstipation & Obstruction (Interfer with bowel activity)
Spasm of sphincter of Oddi(exacerbate biliary or pancreatic pain)
Suppress pain sensation & alter mental status
NSAIDs risk of upper GI inflammation & perforation
Steroids block protective gastric mucous production by chief cells & the inflammatory reaction
to infection ( e.g. Advanced peritonitis)
DRUG HISTORY
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Iran University of medical sciences
Coagulopathy & portal HTN from liver impairment
Intense vasospastic reaction Life threatening HTN
Cardiac & intestinal ischemia
DRUG HISTORY
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Iran University of medical sciences
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Navid Manafi
Iran University of medical sciences
PHYSICAL
EXAMINATION
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Iran University of medical sciences
Patients with peritoneal irritation typically lie
very still in bed during evaluation & often maintain
flexion of knees & hips to tension on Anterior
abdominal wall
pain other than peritoneal irritation
( Ischemic bowel or ureteral or biliary colic)typically cause
the patient to shift & fidget in bed continually while trying
to
find a position that lessens their discomfort
Erythema or edema of skin cellulitis of
abdominal wall
ecchymosis sometimes observed with deeper
necrotizing infections of the fascia or
abdominal structures (e.g. pancreatitis)
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Navid Manafi
Iran University of medical sciences
Bowel sounds quantity & quality
Quiet abd. ileus
Hyperactive Enteritis & early ischemic intestine
Mechanical bowel obstruction high pitched tinkling sounds that tend to come in rushes & A/W pain
echoing sounds when significant luminal distention exists
Bruits in abd. turbulent blood flow in vascular system 70% - 95% : High grade arterial stenoses
also if AV fistula
Use stethoscope to check consistency of information with palpation
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Navid Manafi
Iran University of medical sciences
Percussion
Hyperresonance(tympany to percussion) gas-filled loops of bowel
peritonitis is also assessed by percussion
Firmly tapping the iliac crest,flank,or heel of an extended leg will jar the abdominal viscera & elicit
characteristic pain when peritonitis is present
Palpation
gives most of the information
always begin away from the reported area of pain
involuntary guarding sign of peritonitis(must distinguish from voluntary guarding)
abdominal wall muscle spasm
The examiner applies constant pressure to the abdominal wall,away from the point of maximal pain,while
asking the pt to take a slow deep breath
voluntary guarding abdominal wall muscles relax during inspiration
involuntary guarding spastic & tense
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Navid Manafi
Iran University of medical sciences
Abdominal examination signs
Sign Description Dx /condition
Aaron Pain or pressure in epigastrium or ant. chest with persistent firm pressure to
McBurney’s point
Acute appendicitis
Bassler sharp pain created by compressing appendix between abdominal wall & illiacus chronic appendicitis
Blumberg Transient abd. wall rebound tenderness peritoneal inflammation
Carnett Loss of abdominal tenderness when abd. wall muscles are contracted Intra-abdominal source of
abdominal pain
Chandelier Extreme lower abdominal & pelvic pain with movement of cervix PID
Charcot Intermittent RUQ pain,jaundice & fever choledocholithiasis
Claybrook accentuation of breath & cardiac sounds through abdominal wall ruptured abdominal viscus
Courvoisier Palpable gallbladder in presence of jaundice periampullary tumor
Cruveihier varicose vv. at umbilicus (caput medusa) Portal HTN
Cullen periumbilical bruising
Hemoperitoneum
Danforth shoulder pain on inspiration
Ballance presence of dull percussion note in both flanks,constant on L. side but but
shifting with change of position on R. side
ruptured spleen
Beevor Upward movement of umbilicus paralysis of lower portions
of rectus abdominis
muscles
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Abdominal examination signs
Sign Description Dx / condition
Fothergill abdominal wall mass that does not cross midline & remains palpable
when rectus contracted
rectus muscle hematomas
Grey turner local areas of discoloration around umbilicus & flanks acute hemorrhagic pancreatitis
Iliopsoas elevation & extension of leg against resistance creates pain appendicitis with retrocecal
abscess
Kehr L. shoulder pain when supine & pressure placed on left upper abd. hemoperitoneum(esp from splenic
origin)
Mannkopf increased pulse when painful abd. palpated Absent if malingering
Murphy pain caused by inspiration while applying pressure to RUQ. acute cholecystitis
Obturator flexion & ext. rotation of R. thigh while supine creates hypogastric
pain
pelvic abscess or inflammatory
mass in pelvis
Ransohoff Yellow discoloration of umbilical region ruptured common bile duct
Rovsing Pain at McBurney’s point when compressing the L. lower abd.
Acute appendicitis
Ten Horn Pain caused by gentle traction of R. testicle
Chaussier severe epigastric pain in gravid female prodrome of eclampsia
33
Abdominal examination signs
Sign Description Dx / condition
Cutaneous
hyperesthesia
increased abdominal wall sensation to light touch parietal peritoneal inflammation
2nd to inflammatory intra-
abdominal pathology
Dance slight retraction in area of R. iliac fossa Intussusception
Kustner palpable mass ant. to uterus dermoid cyst of ovary
McClintock HR>100 in 1 hour postpartum postpartum hemorrhage
Puddle alteration in intensity of transmitted sound in intra-abdominal
cavity 2nd to percussion when patient is positioned on all fours &
stethoscope is gradually moved toward flank opposite percussion
free peritoneal fluid
Toma R. sided tympany & L.sided dullness in supine position as a result
of peritoneal inflammation & subsequent mesenteric contraction of
intestine to R. side of abdominal cavity
Inflammatory ascites
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Navid Manafi
Iran University of medical sciences
Carnett’s sign
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Iran University of medical sciences
Charcot’s sign
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Iran University of medical sciences
Cruveihier’s sign
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Iran University of medical sciences
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Grey turner’s sign
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Iran University of medical sciences
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Iran University of medical sciences
Obturator’s sign
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Iran University of medical sciences
Ransohoff’s sign
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Iran University of medical sciences
Rovsing's sign
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Iran University of medical sciences
Beevor’s sign
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Iran University of medical sciences
Dance’s sign
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Iran University of medical sciences
Puddle’s sign
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Navid Manafi
Iran University of medical sciences
Signs helping to localize site Obturator , Psoas , Rovsing’s
of underlying peritonitis
Intra-abdominal VS abd. wall Fothergill & Carnett signs
A DRE needs to be performed in ALL patients with Acute abdominal pain.
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Navid Manafi
Iran University of medical sciences
Evaluation
&
Diagnosis
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Navid Manafi
Iran University of medical sciences
Test indication
Hemoglobin level
WBC count with differential Most pts with acute abd. will have a leukocytosis or bandemia
Electrolyte,BUN,Cr helpful in evaluating effect of vomiting or third space fluid losses
U/A bacterial cystitis,pyelonephritis,endocrine abnormalities (Diabetes or
renal parenchymal disease)
urine culture………UTI
Urine human chorionic gonadotropin level Pregnancy
Amylase,Lipase Pancreatitis (also increase in small bowel infarction or duodenal ulcer
perforation)
{if normal does not exclude pancreatitis}
Total & direct bilirubin levels
LFTs …….. for partial biliary tract causes of acute abdominal painAlkaline phosphatase
Serum aminotransferase
Serum Lactate level in intestinal ischemia or infarction
Stool for Ova & Parasites
C. difficile culture & toxin assay esp in patients with diarrhea
Laboratory studies
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Navid Manafi
Iran University of medical sciences
plain radiograph upright CXR…………………………1 mL air in peritoneum
lat. decubitus abd. radiograph ……….5-10 mL air in peritoneum
(Patients who can’t stand)
75% of patients with perforated duodenal ulcer have enough pneumoperitoneum to be visible with X-ray
Abnormal calcifications 5% of appendicoliths
10% of gallstones Radiopaque
90% of renal stones
Pancreatic calcifications in chronic pancreatitis
AAA calcifications
Visceral a. aneurysm……..splenic,renal,hepatic,mesenteric aa.
Atherosclerosis in visceral vessels
}
IMAGING STUDIES
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Navid Manafi
Iran University of medical sciences
Upright & supine abd. radiograph GOO
Obstruction of small bowel
Complete +ve gas in colon
Partial -ve gas in colon
Volvulus of cecum or sigmoid
IMAGING STUDIES
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Navid Manafi
Iran University of medical sciences
ULTRASOUND
Extremely accurate for gallstones & assessing gallbladder wall thickness & presence of fluid around gallbladder
Determining diameter of extra hepatic & intrahepatic bile ducts
(limited use in detecting common bile duct stones)
Abdominal & Transvaginal U/S………………..Ovaries,Adnexa,Uterus
intraperitoneal fluid
IMAGING STUDIES
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Navid Manafi
Iran University of medical sciences
Imaging modality of choice in acute abdomen 1-Abdominal radiography
2-CT
For appendicitis CT with oral,rectal & IV contrast (Perfect)
CT excellent for differentiating mechanical small bowel obstruction from paralytic ileus
Many patients suffering a blunt abdominal trauma will have altered mental states from coexisting closed
head injuries or from intoxicating substances.
small bowel injury Bowel wall thickening
following blunt trauma Any gas outside of lumen
Intraperitoneal fluid
IMAGING STUDIES
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Navid Manafi
Iran University of medical sciences
Appendicitis
CT scan of uncomplicated
appendicitis.A thick-walled,
distended,retrocecal
appendix
is seen with inflammatory
change
in the surrounding fat
54
Navid Manafi
Iran University of medical sciences
Appendicitis
CT scan of complicated
appendicitis -a retrocecal
appendeceal abscess(A) with
an associated phlegmon
posteriorly found in a 3 W
postpartum, obese
woman.inflammatory change
extends through the flank
musculature into the
subcutaneous fat
55
Navid Manafi
Iran University of medical sciences
Small bowel infarction
A/W mesenteric
venous thrombosis
Note the low density
thrombosed SMV (solid
arrow) & incidental
gallstones(open arrow)
56
Navid Manafi
Iran University of medical sciences
Small bowel infarction
A/W mesenteric
venous thrombosis
Thickening of proximal
small bowel wall (arrow)
coincided with several feet
of infracting small bowel
at time of operation
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Navid Manafi
Iran University of medical sciences
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Iran University of medical sciences
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Iran University of medical sciences
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Iran University of medical sciences
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Iran University of medical sciences
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Iran University of medical sciences
68
IAP Blood flow to organs
Venous return to heart
Upward press on diaphragm peak inspiratory pressure ventilatory efficiency
Risk of esophageal reflux & pulmonary aspiration
consider possibility of Abdominal HTN in any patient who presents with a rigid or significantly distended
abdomen.
Normal IAP = 5-7 mmHg ( in obesity & elevation of head of bed)
Morbid obesity……………………………… normal pressure by 4-8 mmHg
elevation of head of bed to 30 degrees……… normal pressure by 5 mmHg
INTRA-ABDOMINAL PRESSURE MONITORING
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Navid Manafi
Iran University of medical sciences
we measure pressure via bladder by a pressure transducer to a foley catheter
pressure recordings are obtained at end-expiration following instillation of 50 mL of saline into an
otherwise empty bladder
Pressure > 11 mmHg = abdominal HTN
Abdominal HTN=4 grades :
grade 1 medical intervention (maintaing euvolemia,gut decompression with NGT,laxatives & ,
enemas,withdrawing enteral feeding,catheter aspiration of ascitic fluid,abd. wall
relaxation,judicious use of hypotonic IV fluids
grade 2
grade 3
grade 4
}
}Laparotomy
INTRA-ABDOMINAL PRESSURE MONITORING
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Navid Manafi
Iran University of medical sciences
INTRA-ABDOMINAL PRESSURE MONITORING
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Navid Manafi
Iran University of medical sciences
DIFFERENTIAL
DIAGNOSIS
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Navid Manafi
Iran University of medical sciences
Peritoneal lavage………..1000 mL of saline
Preparation for emergency operation:
— IV access should be obtained & any fluid or electrolyte abnormalities corrected
— Almost all patients require antibiotic infusions Gram -ve enteric organism & anaerobes ( initiated
once a presumptive Dx has been made)
— NGT for patients with generalized paralytic ileus likelihood of vomiting & aspiration
— Foley………assess urinary output
prep urine output of 0.5 mL/kg/h
SBP > 100 Adequate IV volume
HR < 100
If significant hypokalemia Get CV line (administering potassium through a peripheral line is limited
by the potential of PHLEBITIS)
Preop acidosis fluid repletion & IV bicarbonate infusion
Acidosis caused by intestinal ischemia or infarction may be refractory preop therapy.
significant anemia is uncommon & preop blood transfusions are usually unnecessary
}
WHAT TO DO…
73
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Navid Manafi
Iran University of medical sciences
ATYPICAL
PATIENTS
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Navid Manafi
Iran University of medical sciences
ATYPICAL PATIENTS
-Greatest threat facing the pregnant patient with acute
abdominal pain is the potential for delayed diagnosis
-The appendix rises out of the pelvis to within a few
centimeters out of the right anterolateral costal margin
late in the 3rd. trimester.
-results of lab studies are altered in pregnancy(e.g.
WBC)
-periop risk is by maintaining physiologic O2 & CO2
levels during surgery, avoiding episodes of hypotension
& minimally manipulating the uterus
PREGNANCY
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Navid Manafi
Iran University of medical sciences
Appendicitis
-Most common non obstetric disease requiring
surgery(1/1500 pregnancies)
-50% - 60% ………..right lateral abdominal
pain,nausea,anorexia
-fever is uncommon unless appendix is perforated with
abdominal sepsis
-Leukocytosis as high as 16000 cells/mm3 is common
in pregnancy,& labor can the count to 21000.Many
authors have suggested that a neutrophil shift > 80%
is suspicious for an acute inflammatory process, e.g.
appendicitis
PREGNANCY
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Navid Manafi
Iran University of medical sciences
APPENDICITIS
1st
Most common non obstetric surgical
diseases in a pregnant woman
BILIARY TRACT
DISORDERS
2nd
BOWEL
OBSTRUCTIONS
3rd
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Navid Manafi
Iran University of medical sciences
Biliary tract disorders……..U/S & Alp(increased by estrogen)
If nuclear scan……foley (so that isotope cleared by the kidneys does not collect near the uterus)
Gallstone pancreatitis & acute cholecystitis should be managed more carefully( 60% fetal loss)
Bowel obstruction……..1-2/4000 deliveries
cause: 66%…..adhesion
25%…..volvulus
3 periods in gestation A/W
risk of obstruction with rapid
changes in uterine size
{
weeks 16-20 ……….uterus grows beyond the pelvis
weeks 32-36………..fetal head descends
early postpartum period
PREGNANCY
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Navid Manafi
Iran University of medical sciences
CPB mesenteric ischemia
paralytic ileus
ogilvie’s syndrome
stress peptic ulceration
acute calculus cholecystitis
acute pancreatitis
vasoactive
medications
ventilator
support
{
CRITICALLY ILL PATIENTS
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Navid Manafi
Iran University of medical sciences
mild-moderate compromise
(less abdominal pain &
delayed fever &
blunted leukocytosis)
Severely compromised Transplant recipients with immunosuppression for > 2months
Cancer patients on chemo ( esp those with neutropenia )
HIV patients with CD4 < 200/mm3
Older patients
diabetics
malnourished
Transplant patients on routine maintenance therapy
Cancer patients
Renal failure patients
HIV patients with CD4 > 200/mm3
{
{
IMMUNOCOMPROMISED PATIENTS
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Navid Manafi
Iran University of medical sciences
-also in lymphoma,leukemia,& AIDS
s&s……..diarrhea , dehydration , abdominal pain , fever , leukocytosis
CT Bowel wall thickening
pancolonic distribution
pericolonic standing
ascitis , generalized mucosal enhancement , diffuse bowel dilation,
double halo sign(IV contrast enhances the mucosa & muscular propria
while edema in submucosa creates an area of low attenuation in
between)
-14% normal CT
Atypical infections -peritoneal tuberculosis
-fungal infections……..aspergillus & endemic
mycoses
CMV,EBV
{
{
PSEUDOMEMBRANOUS COLLITIS
82
Morbidly obese patients
Abdominal sepsis is a more subtle diagnosis & may
only be A/W malaise , shoulder pain , hiccups , SOB
Laparoscopy is a valuable tool here (esp designed
trochars & hand assist ports
83
Navid Manafi
Iran University of medical sciences
ALGORITHMS
IN ACUTE ABDMEN
84
Navid Manafi
Iran University of medical sciences
Navid manafi
medical student,Rasool Akram hospital,Tehran,Iran
acute-onset,severe ,
generalized abdominal pain
85
Navid Manafi
Iran University of medical sciences
Navid manafi
medical student,Rasool Akram hospital,Tehran,Iran
Treatment of gradual-onset , severe ,
generalized abdominal pain
86
Navid Manafi
Iran University of medical sciences
Navid manafi
medical student,Rasool Akram hospital,Tehran,Iran
Treatment of RUQ
abdominal pain
87
Navid Manafi
Iran University of medical sciences
Navid manafi
medical student,Rasool Akram hospital,Tehran,Iran
Treatment of LUQ
abdominal pain
88
Navid Manafi
Iran University of medical sciences
Navid manafi
medical student,Rasool Akram hospital,Tehran,Iran
Treatment of RLQ
abdominal pain
89
Navid Manafi
Iran University of medical sciences
Navid manafi
medical student,Rasool Akram hospital,Tehran,Iran
Treatment of LLQ
abdominal pain
90
Navid Manafi
Iran University of medical sciences
91
Thank
you
92

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Acute abdomen

  • 1. Navid Manafi Medical student 1 Navid Manafi Iran University of medical sciences
  • 2. 2 Navid Manafi Iran University of medical sciences
  • 3. Ronald A. Squires , MD Professor,Department of Surgery,University of Oklahoma Health Sciences Center,Oklahoma city,Oklahoma 3 Navid Manafi Iran University of medical sciences
  • 4. Russell G. Postier, MD John A. Schilling Professor and Chairman,Department of Surgery,University of Oklahoma Health sciences Center,Oklahoma City,Oklahoma 4 Navid Manafi Iran University of medical sciences
  • 5. 5 Navid Manafi Iran University of medical sciences
  • 6. Alex Nagle , MD, FACS Northwestern University Feinberg School of Medicine Chicago,IL 6 Navid Manafi Iran University of medical sciences
  • 7. Dr. Zachary Cope English surgeon 1921 until 1971 7 Navid Manafi Iran University of medical sciences
  • 9. DEFINITION • Sabiston : Signs & symptoms of abdominal pain & tenderness,a clinical presentation that often requires emergency surgical therapy • ACS Surgery : Previously undiagnosed pain that arises suddenly & is of less than 48 hour duration 9 Navid Manafi Iran University of medical sciences
  • 10. • younger : appendicitis older :biliary disease , bowel obstruction intestinal ischemia & Infarction , diverticulitis • surgical dd. A/W acute abdomen : 1-Infection 2-Obstruction 3-Ischemia 4- Perforation W/O : Hx , Ph/E , labs , Imaging 10 Navid Manafi Iran University of medical sciences
  • 11. Surgical Acute Abdominal Conditions 11 Navid Manafi Iran University of medical sciences
  • 12. Surgical Acute Abdominal Conditions 12 Navid Manafi Iran University of medical sciences
  • 13. Abdominal Pain 1-Visceral (vague , mostly midline (epigastrium ,periumbilical , hypogastrium) usually from distention of a hollow viscus 2-Parietal (Sharper & better localized) Sensory innervation of the viscera 13 Navid Manafi Iran University of medical sciences
  • 14. 14 Navid Manafi Iran University of medical sciences
  • 15. Out pouching of fluid from peritoneal membrane Peritoneum: Blood flow permeability formation of fibrinous exudate on its surface Bowel : local or generalized paralysis Adherence between bowel & omentum or abdominal wall & help localize inflammation Abscess : sharply localized pain + normal bowel sounds & GI function Diffuse process(perforated duodenal ulcer): generalized abdominal pain + quiet abdomen 15 Navid Manafi Iran University of medical sciences
  • 16. Entire abdominal cavity or part of visceral or parietal peritoneum sever tenderness on palpation +/- rebound tenderness & guarding causes infections e.g. Gram -ve bacteria or anaerobes noninfectious e.g pancreatitis Primary peritonitis in children (esp by Pneumococcus or Hemolytic Strep spp.) Adults with ESRD on peritoneal dialysis Gram -ve cocci adults with ascites & cirrhosis primary peritonitis esp E.Coli & klebsiella PERITONITIS 16 Navid Manafi Iran University of medical sciences
  • 17. Pain shown with finger (parietal innervation) peritoneal inflammation ……………….. palm of hand (visceral innervation) bowel or solid organ disease sudden onset of excruciating pain intestinal perforation arterial embolization with ischemia biliary colic Pain that develops & worsens over several hh. bowel obstruction (progressive inflammation or infection) colitis cholecystitis Intermittent episodes of pain (colicky pain ) bowel obstruction biliary colic from cystic duct obstruction Genitourinary obstruction HISTORY TAKING PEARLS 17 Navid Manafi Iran University of medical sciences
  • 18. Small bowel pain periumbilical colon pain between umbilicus & pubic symphysis liver pain to shoulder is via C3 - C5 n. roots Genitourinary pain commonly radiates Flank (Splanchnic nn. of T11-L1) Scrotum or Labia (Hypogastric plexus of S2-S4) pain of Bowel obstruction , biliary colic,pancreatitis , diverticulitis , bowel perforation pain of non perforated PUD or gastritis HISTORY TAKING PEARLS 18 Navid Manafi Iran University of medical sciences
  • 19. Patients with peritoneal inflammation will avoid any activity that stretches or jostles the abdomen pain with sudden body movement pain when knees flexed Vomiting may occur because of severe abdominal pain of any cause or as a result of mechanical bowel obstruction or ileum HISTORY TAKING PEARLS 19 Navid Manafi Iran University of medical sciences
  • 20. Many conditions : Vomiting severe abdominal pain Acute surgical abdomen : Severe pain Vomiting (via medullary efferent fibers) Complete obstruction subsequent bowel ischemia or perforation caused by massive distention that can occur Infectious enteritis IBD Parasitic contamination Colonic ischemia A/W Bloody diarrhea Diarrhea in acute abdomen HISTORY TAKING PEARLS Lower abdominal pain in a young lady EP , PID , Mittelschmerz , Severe endometriosis 20
  • 21. 21 Navid Manafi Iran University of medical sciences
  • 22. 22
  • 23. 23
  • 24. 24
  • 25. High dose Narcotic Obstipation & Obstruction (Interfer with bowel activity) Spasm of sphincter of Oddi(exacerbate biliary or pancreatic pain) Suppress pain sensation & alter mental status NSAIDs risk of upper GI inflammation & perforation Steroids block protective gastric mucous production by chief cells & the inflammatory reaction to infection ( e.g. Advanced peritonitis) DRUG HISTORY 25 Navid Manafi Iran University of medical sciences
  • 26. Coagulopathy & portal HTN from liver impairment Intense vasospastic reaction Life threatening HTN Cardiac & intestinal ischemia DRUG HISTORY 26 Navid Manafi Iran University of medical sciences
  • 27. 27 Navid Manafi Iran University of medical sciences
  • 29. Patients with peritoneal irritation typically lie very still in bed during evaluation & often maintain flexion of knees & hips to tension on Anterior abdominal wall pain other than peritoneal irritation ( Ischemic bowel or ureteral or biliary colic)typically cause the patient to shift & fidget in bed continually while trying to find a position that lessens their discomfort Erythema or edema of skin cellulitis of abdominal wall ecchymosis sometimes observed with deeper necrotizing infections of the fascia or abdominal structures (e.g. pancreatitis) 29 Navid Manafi Iran University of medical sciences
  • 30. Bowel sounds quantity & quality Quiet abd. ileus Hyperactive Enteritis & early ischemic intestine Mechanical bowel obstruction high pitched tinkling sounds that tend to come in rushes & A/W pain echoing sounds when significant luminal distention exists Bruits in abd. turbulent blood flow in vascular system 70% - 95% : High grade arterial stenoses also if AV fistula Use stethoscope to check consistency of information with palpation 30 Navid Manafi Iran University of medical sciences
  • 31. Percussion Hyperresonance(tympany to percussion) gas-filled loops of bowel peritonitis is also assessed by percussion Firmly tapping the iliac crest,flank,or heel of an extended leg will jar the abdominal viscera & elicit characteristic pain when peritonitis is present Palpation gives most of the information always begin away from the reported area of pain involuntary guarding sign of peritonitis(must distinguish from voluntary guarding) abdominal wall muscle spasm The examiner applies constant pressure to the abdominal wall,away from the point of maximal pain,while asking the pt to take a slow deep breath voluntary guarding abdominal wall muscles relax during inspiration involuntary guarding spastic & tense 31 Navid Manafi Iran University of medical sciences
  • 32. Abdominal examination signs Sign Description Dx /condition Aaron Pain or pressure in epigastrium or ant. chest with persistent firm pressure to McBurney’s point Acute appendicitis Bassler sharp pain created by compressing appendix between abdominal wall & illiacus chronic appendicitis Blumberg Transient abd. wall rebound tenderness peritoneal inflammation Carnett Loss of abdominal tenderness when abd. wall muscles are contracted Intra-abdominal source of abdominal pain Chandelier Extreme lower abdominal & pelvic pain with movement of cervix PID Charcot Intermittent RUQ pain,jaundice & fever choledocholithiasis Claybrook accentuation of breath & cardiac sounds through abdominal wall ruptured abdominal viscus Courvoisier Palpable gallbladder in presence of jaundice periampullary tumor Cruveihier varicose vv. at umbilicus (caput medusa) Portal HTN Cullen periumbilical bruising Hemoperitoneum Danforth shoulder pain on inspiration Ballance presence of dull percussion note in both flanks,constant on L. side but but shifting with change of position on R. side ruptured spleen Beevor Upward movement of umbilicus paralysis of lower portions of rectus abdominis muscles 32
  • 33. Abdominal examination signs Sign Description Dx / condition Fothergill abdominal wall mass that does not cross midline & remains palpable when rectus contracted rectus muscle hematomas Grey turner local areas of discoloration around umbilicus & flanks acute hemorrhagic pancreatitis Iliopsoas elevation & extension of leg against resistance creates pain appendicitis with retrocecal abscess Kehr L. shoulder pain when supine & pressure placed on left upper abd. hemoperitoneum(esp from splenic origin) Mannkopf increased pulse when painful abd. palpated Absent if malingering Murphy pain caused by inspiration while applying pressure to RUQ. acute cholecystitis Obturator flexion & ext. rotation of R. thigh while supine creates hypogastric pain pelvic abscess or inflammatory mass in pelvis Ransohoff Yellow discoloration of umbilical region ruptured common bile duct Rovsing Pain at McBurney’s point when compressing the L. lower abd. Acute appendicitis Ten Horn Pain caused by gentle traction of R. testicle Chaussier severe epigastric pain in gravid female prodrome of eclampsia 33
  • 34. Abdominal examination signs Sign Description Dx / condition Cutaneous hyperesthesia increased abdominal wall sensation to light touch parietal peritoneal inflammation 2nd to inflammatory intra- abdominal pathology Dance slight retraction in area of R. iliac fossa Intussusception Kustner palpable mass ant. to uterus dermoid cyst of ovary McClintock HR>100 in 1 hour postpartum postpartum hemorrhage Puddle alteration in intensity of transmitted sound in intra-abdominal cavity 2nd to percussion when patient is positioned on all fours & stethoscope is gradually moved toward flank opposite percussion free peritoneal fluid Toma R. sided tympany & L.sided dullness in supine position as a result of peritoneal inflammation & subsequent mesenteric contraction of intestine to R. side of abdominal cavity Inflammatory ascites 34 Navid Manafi Iran University of medical sciences
  • 35. Carnett’s sign 35 Navid Manafi Iran University of medical sciences
  • 36. Charcot’s sign 36 Navid Manafi Iran University of medical sciences
  • 37. Cruveihier’s sign 37 Navid Manafi Iran University of medical sciences
  • 38. 38
  • 39. Grey turner’s sign 39 Navid Manafi Iran University of medical sciences
  • 40. 40 Navid Manafi Iran University of medical sciences
  • 41. Obturator’s sign 41 Navid Manafi Iran University of medical sciences
  • 42. Ransohoff’s sign 42 Navid Manafi Iran University of medical sciences
  • 43. Rovsing's sign 43 Navid Manafi Iran University of medical sciences
  • 44. Beevor’s sign 44 Navid Manafi Iran University of medical sciences
  • 45. Dance’s sign 45 Navid Manafi Iran University of medical sciences
  • 46. Puddle’s sign 46 Navid Manafi Iran University of medical sciences
  • 47. Signs helping to localize site Obturator , Psoas , Rovsing’s of underlying peritonitis Intra-abdominal VS abd. wall Fothergill & Carnett signs A DRE needs to be performed in ALL patients with Acute abdominal pain. 47 Navid Manafi Iran University of medical sciences
  • 49. Test indication Hemoglobin level WBC count with differential Most pts with acute abd. will have a leukocytosis or bandemia Electrolyte,BUN,Cr helpful in evaluating effect of vomiting or third space fluid losses U/A bacterial cystitis,pyelonephritis,endocrine abnormalities (Diabetes or renal parenchymal disease) urine culture………UTI Urine human chorionic gonadotropin level Pregnancy Amylase,Lipase Pancreatitis (also increase in small bowel infarction or duodenal ulcer perforation) {if normal does not exclude pancreatitis} Total & direct bilirubin levels LFTs …….. for partial biliary tract causes of acute abdominal painAlkaline phosphatase Serum aminotransferase Serum Lactate level in intestinal ischemia or infarction Stool for Ova & Parasites C. difficile culture & toxin assay esp in patients with diarrhea Laboratory studies 49 Navid Manafi Iran University of medical sciences
  • 50. plain radiograph upright CXR…………………………1 mL air in peritoneum lat. decubitus abd. radiograph ……….5-10 mL air in peritoneum (Patients who can’t stand) 75% of patients with perforated duodenal ulcer have enough pneumoperitoneum to be visible with X-ray Abnormal calcifications 5% of appendicoliths 10% of gallstones Radiopaque 90% of renal stones Pancreatic calcifications in chronic pancreatitis AAA calcifications Visceral a. aneurysm……..splenic,renal,hepatic,mesenteric aa. Atherosclerosis in visceral vessels } IMAGING STUDIES 50 Navid Manafi Iran University of medical sciences
  • 51. Upright & supine abd. radiograph GOO Obstruction of small bowel Complete +ve gas in colon Partial -ve gas in colon Volvulus of cecum or sigmoid IMAGING STUDIES 51 Navid Manafi Iran University of medical sciences
  • 52. ULTRASOUND Extremely accurate for gallstones & assessing gallbladder wall thickness & presence of fluid around gallbladder Determining diameter of extra hepatic & intrahepatic bile ducts (limited use in detecting common bile duct stones) Abdominal & Transvaginal U/S………………..Ovaries,Adnexa,Uterus intraperitoneal fluid IMAGING STUDIES 52 Navid Manafi Iran University of medical sciences
  • 53. Imaging modality of choice in acute abdomen 1-Abdominal radiography 2-CT For appendicitis CT with oral,rectal & IV contrast (Perfect) CT excellent for differentiating mechanical small bowel obstruction from paralytic ileus Many patients suffering a blunt abdominal trauma will have altered mental states from coexisting closed head injuries or from intoxicating substances. small bowel injury Bowel wall thickening following blunt trauma Any gas outside of lumen Intraperitoneal fluid IMAGING STUDIES 53 Navid Manafi Iran University of medical sciences
  • 54. Appendicitis CT scan of uncomplicated appendicitis.A thick-walled, distended,retrocecal appendix is seen with inflammatory change in the surrounding fat 54 Navid Manafi Iran University of medical sciences
  • 55. Appendicitis CT scan of complicated appendicitis -a retrocecal appendeceal abscess(A) with an associated phlegmon posteriorly found in a 3 W postpartum, obese woman.inflammatory change extends through the flank musculature into the subcutaneous fat 55 Navid Manafi Iran University of medical sciences
  • 56. Small bowel infarction A/W mesenteric venous thrombosis Note the low density thrombosed SMV (solid arrow) & incidental gallstones(open arrow) 56 Navid Manafi Iran University of medical sciences
  • 57. Small bowel infarction A/W mesenteric venous thrombosis Thickening of proximal small bowel wall (arrow) coincided with several feet of infracting small bowel at time of operation 57 Navid Manafi Iran University of medical sciences
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  • 62. 62 Navid Manafi Iran University of medical sciences
  • 63. 63 Navid Manafi Iran University of medical sciences
  • 64. 64 Navid Manafi Iran University of medical sciences
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  • 67. 67 Navid Manafi Iran University of medical sciences
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  • 69. IAP Blood flow to organs Venous return to heart Upward press on diaphragm peak inspiratory pressure ventilatory efficiency Risk of esophageal reflux & pulmonary aspiration consider possibility of Abdominal HTN in any patient who presents with a rigid or significantly distended abdomen. Normal IAP = 5-7 mmHg ( in obesity & elevation of head of bed) Morbid obesity……………………………… normal pressure by 4-8 mmHg elevation of head of bed to 30 degrees……… normal pressure by 5 mmHg INTRA-ABDOMINAL PRESSURE MONITORING 69 Navid Manafi Iran University of medical sciences
  • 70. we measure pressure via bladder by a pressure transducer to a foley catheter pressure recordings are obtained at end-expiration following instillation of 50 mL of saline into an otherwise empty bladder Pressure > 11 mmHg = abdominal HTN Abdominal HTN=4 grades : grade 1 medical intervention (maintaing euvolemia,gut decompression with NGT,laxatives & , enemas,withdrawing enteral feeding,catheter aspiration of ascitic fluid,abd. wall relaxation,judicious use of hypotonic IV fluids grade 2 grade 3 grade 4 } }Laparotomy INTRA-ABDOMINAL PRESSURE MONITORING 70 Navid Manafi Iran University of medical sciences
  • 71. INTRA-ABDOMINAL PRESSURE MONITORING 71 Navid Manafi Iran University of medical sciences
  • 73. Peritoneal lavage………..1000 mL of saline Preparation for emergency operation: — IV access should be obtained & any fluid or electrolyte abnormalities corrected — Almost all patients require antibiotic infusions Gram -ve enteric organism & anaerobes ( initiated once a presumptive Dx has been made) — NGT for patients with generalized paralytic ileus likelihood of vomiting & aspiration — Foley………assess urinary output prep urine output of 0.5 mL/kg/h SBP > 100 Adequate IV volume HR < 100 If significant hypokalemia Get CV line (administering potassium through a peripheral line is limited by the potential of PHLEBITIS) Preop acidosis fluid repletion & IV bicarbonate infusion Acidosis caused by intestinal ischemia or infarction may be refractory preop therapy. significant anemia is uncommon & preop blood transfusions are usually unnecessary } WHAT TO DO… 73
  • 74. 74 Navid Manafi Iran University of medical sciences
  • 76. ATYPICAL PATIENTS -Greatest threat facing the pregnant patient with acute abdominal pain is the potential for delayed diagnosis -The appendix rises out of the pelvis to within a few centimeters out of the right anterolateral costal margin late in the 3rd. trimester. -results of lab studies are altered in pregnancy(e.g. WBC) -periop risk is by maintaining physiologic O2 & CO2 levels during surgery, avoiding episodes of hypotension & minimally manipulating the uterus PREGNANCY 76 Navid Manafi Iran University of medical sciences
  • 77. Appendicitis -Most common non obstetric disease requiring surgery(1/1500 pregnancies) -50% - 60% ………..right lateral abdominal pain,nausea,anorexia -fever is uncommon unless appendix is perforated with abdominal sepsis -Leukocytosis as high as 16000 cells/mm3 is common in pregnancy,& labor can the count to 21000.Many authors have suggested that a neutrophil shift > 80% is suspicious for an acute inflammatory process, e.g. appendicitis PREGNANCY 77 Navid Manafi Iran University of medical sciences
  • 78. APPENDICITIS 1st Most common non obstetric surgical diseases in a pregnant woman BILIARY TRACT DISORDERS 2nd BOWEL OBSTRUCTIONS 3rd 78 Navid Manafi Iran University of medical sciences
  • 79. Biliary tract disorders……..U/S & Alp(increased by estrogen) If nuclear scan……foley (so that isotope cleared by the kidneys does not collect near the uterus) Gallstone pancreatitis & acute cholecystitis should be managed more carefully( 60% fetal loss) Bowel obstruction……..1-2/4000 deliveries cause: 66%…..adhesion 25%…..volvulus 3 periods in gestation A/W risk of obstruction with rapid changes in uterine size { weeks 16-20 ……….uterus grows beyond the pelvis weeks 32-36………..fetal head descends early postpartum period PREGNANCY 79 Navid Manafi Iran University of medical sciences
  • 80. CPB mesenteric ischemia paralytic ileus ogilvie’s syndrome stress peptic ulceration acute calculus cholecystitis acute pancreatitis vasoactive medications ventilator support { CRITICALLY ILL PATIENTS 80 Navid Manafi Iran University of medical sciences
  • 81. mild-moderate compromise (less abdominal pain & delayed fever & blunted leukocytosis) Severely compromised Transplant recipients with immunosuppression for > 2months Cancer patients on chemo ( esp those with neutropenia ) HIV patients with CD4 < 200/mm3 Older patients diabetics malnourished Transplant patients on routine maintenance therapy Cancer patients Renal failure patients HIV patients with CD4 > 200/mm3 { { IMMUNOCOMPROMISED PATIENTS 81 Navid Manafi Iran University of medical sciences
  • 82. -also in lymphoma,leukemia,& AIDS s&s……..diarrhea , dehydration , abdominal pain , fever , leukocytosis CT Bowel wall thickening pancolonic distribution pericolonic standing ascitis , generalized mucosal enhancement , diffuse bowel dilation, double halo sign(IV contrast enhances the mucosa & muscular propria while edema in submucosa creates an area of low attenuation in between) -14% normal CT Atypical infections -peritoneal tuberculosis -fungal infections……..aspergillus & endemic mycoses CMV,EBV { { PSEUDOMEMBRANOUS COLLITIS 82
  • 83. Morbidly obese patients Abdominal sepsis is a more subtle diagnosis & may only be A/W malaise , shoulder pain , hiccups , SOB Laparoscopy is a valuable tool here (esp designed trochars & hand assist ports 83 Navid Manafi Iran University of medical sciences
  • 84. ALGORITHMS IN ACUTE ABDMEN 84 Navid Manafi Iran University of medical sciences
  • 85. Navid manafi medical student,Rasool Akram hospital,Tehran,Iran acute-onset,severe , generalized abdominal pain 85 Navid Manafi Iran University of medical sciences
  • 86. Navid manafi medical student,Rasool Akram hospital,Tehran,Iran Treatment of gradual-onset , severe , generalized abdominal pain 86 Navid Manafi Iran University of medical sciences
  • 87. Navid manafi medical student,Rasool Akram hospital,Tehran,Iran Treatment of RUQ abdominal pain 87 Navid Manafi Iran University of medical sciences
  • 88. Navid manafi medical student,Rasool Akram hospital,Tehran,Iran Treatment of LUQ abdominal pain 88 Navid Manafi Iran University of medical sciences
  • 89. Navid manafi medical student,Rasool Akram hospital,Tehran,Iran Treatment of RLQ abdominal pain 89 Navid Manafi Iran University of medical sciences
  • 90. Navid manafi medical student,Rasool Akram hospital,Tehran,Iran Treatment of LLQ abdominal pain 90 Navid Manafi Iran University of medical sciences
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