Blood pressure is generated by the contraction of the heart ventricle which pumps blood through narrow capillaries and arterioles, creating resistance. Systolic pressure occurs when the heart contracts while diastolic pressure is lower but present when arteriole walls contract. Regulation involves oscillation through signals that change smooth muscle state in arteriole walls, causing vasoconstriction or vasodilation. Gravity also impacts as animals like giraffes have higher blood pressure to pump blood against gravity to the brain.