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Cardiovascular System
Heart Structure

•   Hollow
•   Located within the mediastinum of the thorax.
•   Base is attached to several large blood vessels.
•   Distal end extends downward and to the left
    forming a blunt apex at the fifth intercostal
    space.
Pericardium or
pericardial sac covers
the heart.
The inner layer of the pericardium is called the visceral pericardium (epicardium)
which covers the heart.
The parietal pericardium forms the inner lining of the fibrous pericardium.
The fibrous pericardium is tough and composed of mostly connective tissue.
Between the layers is the pericardial cavity which has pericardial fluid that
lubricates the membranes to reduce friction when the heart moves.
The heart consists of three different layers
Mitral Valve Closed
Mitral Valve Open
Semilunar Valve Function
Tricuspid Valve




Chordae Tendineae
Pulmonary
and
Systemic
Bloodflow
Circumflex artery – supplies the blood to the walls of the left atrium and left
                    ventricle.

Left anterior descending artery – supplies the walls of both ventricles.

Posterior interventricular artery – supplies the walls of both ventricles.

Marginal artery – supplies the walls of the right atrium and right ventricle.
Heart Actions
• Atrial systole is when the atria contract while
  the ventricles relax which is called ventricular
  diastole.
• Thus systolic and diastolic blood pressure.
• This series of contraction and relaxation is
  called a cardiac cycle.
Cardiac Cycle
Heart Sounds
• “Lubb” heart sound occurs during the
  ventricular contraction when the A-V valves
  are closing.
• “Dubb” heart sound occurs during ventricular
  relaxation when the pulmonary and aortic
  valves are closing.
• A heart murmur is when the heart valves fail
  to close completely causing leakage.
Sinoatrial Node



AtrioVentricular Node




Atrioventricular Bundle



    Purkinje Fibers

Heart Conduction System
Sympathetic & Parasympathetic
          Nervous Systems
• Physical exercise, body temperature, and
  concentration of various ions affect heartbeat.
• Branches of sympathetic and parasympathetic nerve
  fibers innervate the S-A and A-V nodes.
• Parasympathetic impulses decrease heart action,
  sympathetic increases heart action.
• Cardiac center in the medulla oblongata regulates
  autonomic impulses to the heart.
Effects of K+ & Ca2+

• Potassium and calcium are two ions that
  influence heart action and are the most
  important.
• Potassium affects the electrical potential of the
  cell membrane.
• Calcium ions are needed more for cardiac muscles
Conditions
• Hyperkalemia (excessive potassium ions) decreases
  the rate and force of cardiac contractions.
• Very high amounts may block cardiac impulses.
• Hypokalemia is low potassium and can cause an
  abnormal arrhythmia.
• Hypercalcemia increases heart action causing a
  prolonged contraction.
• Hypocalcemia depresses heart action.
Arteries are strong, elastic
vessels adapted for carrying
blood away from the heart
under high pressure.

Three distinct layers:
Endothelium – Inner most
layer. Rich in elastic and
collagenous fibers. Called the
tunica interna.

Middle layer – Tunica media.
Smooth muscle fibers, thick
layer of elastic connective
tissue.

Outer layer – Tunica externa.
Attaches the artery to tissues.
Contains vasa vasorum that gives
Rise to capillaries
• Vasomotor fibers stimulate smooth muscle to contract, thus
  reducing the diameter of the vessel.
• This is called vasoconstriction.
• Vasodilation changes the diameter of the vessel that
  influences the blood flow and pressure.
• Arterioles are microscopic continuations of arteries that give
  off branches called metarterioles that join capillaries.
• If arteries are cut they spurt blood due to the high pressure of
  the heart.
Venules are microscopic vessels
That continue from capillaries into
To form veins.

Veins have valves and are
Pushed back if blood begins
To back up in a vein.

Valves aid in the return of
Blood to the heart.

Arterial blood loss will cause
a sympathetic nerve impulse
to stimulate vein walls to
return more blood to the
heart to maintain blood
pressure.
Capillaries exchanges nutrients, gases, and metabolic by-products between the
Capillary blood and tissue fluid.

Diffusion provides the most important means of transport. The pathways depend
on lipid solubilities.

Filtration causes a net outward movement of fluid at the arteriolar end of a
capillary.

Osmosis causes a net inward movement of fluid at the venular end of a capillary.

Plasma proteins generally stay in the blood.
Blood Pressure
• Arterial blood pressure is produced by heart action; it rises
  and falls with phases of the cardiac cycle.
• Systolic pressure occurs when the ventricle contracts;
  diastolic pressure occurs when the ventricle relaxes.
• Heart action, blood volume, resistance to flow and blood
  viscosity influence arterial blood pressure.
• Blood pressure is controlled by cardiac output.
• The more blood that enters the ventricle the greater the
  stroke volume and the greater the cardiac output.
Venous Blood Flow

• Not a direct result of heart action.
• Skeletal muscle contraction, breathing
  movements and vasoconstriction influence
  the flow.
• Venous constriction can increase venous
  pressure and blood flow.

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Cardiovascular system

  • 2. Heart Structure • Hollow • Located within the mediastinum of the thorax. • Base is attached to several large blood vessels. • Distal end extends downward and to the left forming a blunt apex at the fifth intercostal space.
  • 3. Pericardium or pericardial sac covers the heart.
  • 4.
  • 5. The inner layer of the pericardium is called the visceral pericardium (epicardium) which covers the heart. The parietal pericardium forms the inner lining of the fibrous pericardium. The fibrous pericardium is tough and composed of mostly connective tissue. Between the layers is the pericardial cavity which has pericardial fluid that lubricates the membranes to reduce friction when the heart moves.
  • 6. The heart consists of three different layers
  • 7.
  • 8.
  • 9.
  • 15.
  • 16. Circumflex artery – supplies the blood to the walls of the left atrium and left ventricle. Left anterior descending artery – supplies the walls of both ventricles. Posterior interventricular artery – supplies the walls of both ventricles. Marginal artery – supplies the walls of the right atrium and right ventricle.
  • 17. Heart Actions • Atrial systole is when the atria contract while the ventricles relax which is called ventricular diastole. • Thus systolic and diastolic blood pressure. • This series of contraction and relaxation is called a cardiac cycle.
  • 19. Heart Sounds • “Lubb” heart sound occurs during the ventricular contraction when the A-V valves are closing. • “Dubb” heart sound occurs during ventricular relaxation when the pulmonary and aortic valves are closing. • A heart murmur is when the heart valves fail to close completely causing leakage.
  • 20. Sinoatrial Node AtrioVentricular Node Atrioventricular Bundle Purkinje Fibers Heart Conduction System
  • 21.
  • 22.
  • 23.
  • 24.
  • 25.
  • 26. Sympathetic & Parasympathetic Nervous Systems • Physical exercise, body temperature, and concentration of various ions affect heartbeat. • Branches of sympathetic and parasympathetic nerve fibers innervate the S-A and A-V nodes. • Parasympathetic impulses decrease heart action, sympathetic increases heart action. • Cardiac center in the medulla oblongata regulates autonomic impulses to the heart.
  • 27.
  • 28. Effects of K+ & Ca2+ • Potassium and calcium are two ions that influence heart action and are the most important. • Potassium affects the electrical potential of the cell membrane. • Calcium ions are needed more for cardiac muscles
  • 29. Conditions • Hyperkalemia (excessive potassium ions) decreases the rate and force of cardiac contractions. • Very high amounts may block cardiac impulses. • Hypokalemia is low potassium and can cause an abnormal arrhythmia. • Hypercalcemia increases heart action causing a prolonged contraction. • Hypocalcemia depresses heart action.
  • 30. Arteries are strong, elastic vessels adapted for carrying blood away from the heart under high pressure. Three distinct layers: Endothelium – Inner most layer. Rich in elastic and collagenous fibers. Called the tunica interna. Middle layer – Tunica media. Smooth muscle fibers, thick layer of elastic connective tissue. Outer layer – Tunica externa. Attaches the artery to tissues. Contains vasa vasorum that gives Rise to capillaries
  • 31. • Vasomotor fibers stimulate smooth muscle to contract, thus reducing the diameter of the vessel. • This is called vasoconstriction. • Vasodilation changes the diameter of the vessel that influences the blood flow and pressure. • Arterioles are microscopic continuations of arteries that give off branches called metarterioles that join capillaries. • If arteries are cut they spurt blood due to the high pressure of the heart.
  • 32. Venules are microscopic vessels That continue from capillaries into To form veins. Veins have valves and are Pushed back if blood begins To back up in a vein. Valves aid in the return of Blood to the heart. Arterial blood loss will cause a sympathetic nerve impulse to stimulate vein walls to return more blood to the heart to maintain blood pressure.
  • 33. Capillaries exchanges nutrients, gases, and metabolic by-products between the Capillary blood and tissue fluid. Diffusion provides the most important means of transport. The pathways depend on lipid solubilities. Filtration causes a net outward movement of fluid at the arteriolar end of a capillary. Osmosis causes a net inward movement of fluid at the venular end of a capillary. Plasma proteins generally stay in the blood.
  • 34.
  • 35. Blood Pressure • Arterial blood pressure is produced by heart action; it rises and falls with phases of the cardiac cycle. • Systolic pressure occurs when the ventricle contracts; diastolic pressure occurs when the ventricle relaxes. • Heart action, blood volume, resistance to flow and blood viscosity influence arterial blood pressure. • Blood pressure is controlled by cardiac output. • The more blood that enters the ventricle the greater the stroke volume and the greater the cardiac output.
  • 36. Venous Blood Flow • Not a direct result of heart action. • Skeletal muscle contraction, breathing movements and vasoconstriction influence the flow. • Venous constriction can increase venous pressure and blood flow.

Editor's Notes

  1. Features of the heart especially the systemic and pulmonary blood vessels chambers and valves.