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International Conference on Informatics for Development 2011 (ICID 2011)



  Avian Influenza (H5N1) Expert System using Dempster-Shafer
                           Theory
                                     Andino Maseleno, Md. Mahmud Hasan
                 Department of Computer Science, Faculty of Science, Universiti Brunei Darussalam
                         Jalan Tungku Link, Gadong BE 1410, Negara Brunei Darussalam
                        E-mail: andinomaseleno@yahoo.com, mahmud.hasan@ubd.edu.bn


Abstract— Based on Cumulative Number of Confirmed           challenges with pandemic preparedness as there may be a
Human Cases of Avian Influenza (H5N1) Reported to           higher death rate in developing countries compared with
World Health Organization (WHO) in the 2011 from            more developed countries [5]. In this research, we use
15 countries, Indonesia has the largest number death        chicken as research object because chicken population
because Avian Influenza which 146 deaths. In this           has grown very fast in Lampung Province in the 2009,
research, the researcher built an Avian Influenza           native chicken population around 11,234,890, broiler
(H5N1) Expert System for identifying avian influenza        population around 15,879,617, layer population around
disease and displaying the result of identification         3,327,847. Lampung Province has been divided into 10
process. In this paper, we describe five symptoms as        regencies, 204 districts and 2279 villages with area of
major symptoms which include depression, combs,             3,528,835 hectare [6].
wattle, bluish face region,      swollen face region,           Expert System is a computer application of artificial
narrowness of eyes, and balance disorders. We use           intelligence [7],[9],[10] which contains a knowledge base
chicken as research object. Research location is in the     and an inference engine [8]. Since such programs attempt
Lampung Province, South Sumatera. The researcher            to emulate the thinking patterns of an expert, it is natural
reason to choose Lampung Province in South                  that the first work was done in artificial intelligence
Sumatera on the basis that has a high poultry               circles. Among the first expert systems were the 1965
population. Dempster-Shafer theory to quantify the          Dendral programs [11], which determined molecular
degree of belief as inference engine in expert system,      structure from mass spectrometer data; R1 [12] used to
our approach uses Dempster-Shafer theory to                 configure computer systems; and MYCIN [13] for
combine beliefs under conditions of uncertainty and         medical diagnosis. The basic idea behind expert system is
ignorance, and allows quantitative measurement of           simply that expertise, which is the vast body of task-
the belief and plausibility in our identification result.   specific knowledge, is transferred from a human to a
The result reveal that Avian Influenza (H5N1) Expert        computer. This knowledge is then stored in the computer
System has successfully identified the existence of         and users call upon the computer for specific advice as
avian influenza and displaying the result of                needed. The computer can make inferences and arrive at
identification process.                                     a specific conclusion. Then like a human consultant, it
                                                            gives advices and explains, if necessary, the logic behind
   Keywords- avian influenza (H5N1), expert system,         the advice [14]. Some expert systems for diagnosis in
uncertainty, dempster-shafer theory                         avian influenza have been developed which were expert
                                                            system for avian influenza disease using Visual
                                                            Basic.NET [15],         and web based [16]. Actually,
                   I.   INTRODUCTION                        according to researchers knowledge, Dempster-Shafer
    Historically, outbreaks of avian influenza first        theory of evidence has never been used for built an expert
occurred in Italy in the 1878, when it was a lot of dead    system for identifying avian influenza.
birds [1]. Then came another outbreak of Avian Influenza        The remainder is organized as follows. The
in Scotland in the 1959 [2]. The virus that causes Avian    uncertainty in expert system is briefly reviewed in Section
                                                            2. Section 3 details the proposed Dempster-Shafer Theory.
Influenza in Italy and Scotland are the current strain of
                                                            Architecture of Avian Influenza (H5N1) Expert System in
H5N1 virus appeared again attacked poultry and humans       Section 4. The experimental results are presented in
in various countries in Asia, including Indonesia, which    Section 5, and final remarks are concluded in Section 6.
caused many deaths in humans [3].
    Avian influenza virus H5N1, which has been limited
to poultry, now has spread to migrating birds and has
                                                                    II.   UNCERTAINTY IN EXPERT SYSTEM
emerged in mammals and among the human population.
It presents a distinct threat of a pandemic for which the       The construction of expert and other intelligent
World Health Organization and other organizations are       computer systems requires sophisticated mechanism for
making preparations. In the 2005, the World Health          representing and reasoning with uncertain information.
Assembly urged its Member States to develop national        At least three forms of uncertainty can be identified as
preparedness plans for pandemic influenza [4].              playing a significant role in these types of systems. The
Developing countries face particular planning and other     first of these possibilistic uncertainty appears in situations


ISSN:2088-5520                                              C2-93
International Conference on Informatics for Development 2011 (ICID 2011)


where the value of a variable can only be narrowed down                  related question. The advantages of the Dempster-Shafer
to a set of values one of which is the actual value of the               theory as follows:
variable. The second kind of uncertainty is related to                   1. It has the ability to model information in a flexible
situations in which there exists uncertainty as to                           way without requiring a probability to be assigned to
satisfaction of a predicate by an element. This is                           each element in a set,
manifested by concepts which have imprecise or gray                      2. It provides a convenient and simple mechanism
boundaries. A very powerful tool for handling this type                      (Dempster's combination rule) for combining two or
of uncertainty which also handles the first type of                          more pieces of evidence under certain conditions.
uncertainty is the fuzzy set. The third type of uncertainty              3. It can model ignorance explicitly.
is related to situations in which the value of a variable                4. Rejection of the law of additivity for belief in disjoint
assumes can be modeled by the performance of a random                        propositions.
experiment [17]. Figure 1 shows the process for dealing                  Avian Influenza (H5N1) Expert System using Dempster-
with uncertainty in Avian Influenza (H5N1) Expert                        Shafer theory in the decision support process. Flowchart
System.                                                                  of Avian Influenza (H5N1) Expert System shown in
                                                                         Figure 1.
Step 1


                                                                                 Start
 Representation of uncertainty      Alternative Rule
   on the set of basic events



                                                                                               Yes                   Input
                                                                              Symptoms                           m1 (B) m2 (C)
Step 2                                   Step 3



                                                                                    No
 Merging uncertain information                         Conclusion

                                                                              m (A) = 1




 Figure 1. The process for dealing with uncertainty in Avian Influenza
                        (H5N1) Expert System
                                                                                 End

In step 1, an expert provides uncertain knowledge in the
form of rules with the possibility. These rules are                         Figure 2. Flowchart of Avian Influenza (H5N1) Expert System
probability values. In step 2, the uncertain knowledge on
a set of basic events can be directly used to draw                       The consultation process begins with selecting the
conclusions in simple cases (step 3). However, in many                   symptoms. If there are symptoms then will calculate, The
cases the various events associated with each other.                     Dempster-Shafer theory provides a rule to combine
Therefore, it is necessary to combine the information                    evidences from independent observers and into a single
contained in step 1 into the global value system. In step 3,             and more informative hint. Evidence theory is based on
the goal is knowledge-based systems draw conclusions. It                 belief function and plausible reasoning. First of all, we
is derived from uncertain knowledge in steps 1 and 2, and                must define a frame of discernment, indicated by the sign
is usually implemented by an inference engine. Working                   Θ . The sign 2Θ indicates the set composed of all the
with the inference engine, the expert can adjust the input               subset generated by the frame of discernment. For a
that they enter in Step 1 after displaying the results in                hypothesis set, denoted by A, m(A)→[0,1].
steps 2 and 3.
                                                                         m( )=0

           III.    DEMPSTER-SHAFER THEORY                                                                                                 (1)

                                                                         ∅ is the sign of an empty set. The function m is the basic
    The Dempster-Shafer theory was first introduced by
                                                                         probability assignment. Dempster's rule of combination
Dempster [18] and then extended by shafer [19], but the
                                                                         combines two independent sets of mass assignments.
kind of reasoning the theory uses can be found as far back
                                                                                       (∅) = 0                                  (2)
as the seventeenth century. This theory is actually an
extension to classic probabilistic uncertainty modeling.
                                                                                                                                          (3)
Whereas the Bayesian theory requires probabilities for
each question of interest, belief functions allow us to base
degrees of belief for on question on probabilities for a



ISSN:2088-5520                                                           C2-94
International Conference on Informatics for Development 2011 (ICID 2011)


Where                                                                 with structured interviews. In the structured interviews,
                                                                      we revised and discussed in depth familiar tasks to clarify
                                                                (4)   questions.

                                                                      4.2 Knowledge Base
                                                                          A critical aspect of building an expert system is
    The results are that Avian Influenza (H5N1) Expert                formulating the scope of the problem and gleaning from
System successfully identifying disease and displaying                the source expert the domain information needed to solve
the result of identification process.                                 the problem. The reliability of an expert system depends
                                                                      on the quality of knowledge contained in the knowledge
                                                                      base. In this research, we built a Avian Influenza (H5N1)
      IV.    AVIAN INFLUENZA (H5N1) EXPERT                            Expert System and we describe five symptoms which
                      SYSTEM                                          include depression, combs, wattle, bluish face region,
    Avian Influenza (H5N1) Expert System has four main                swollen face region, narrowness of eyes, and balance
architectural components that are the knowledge base, the             disorders. Knowledge of which input on the testing of
inference engine, the knowledge acquisition module, and               this expert system can be seen in Table I.
the user interface for input/output. Figure 3 shows
architecture of Avian Influenza (H5N1) Expert System.                               TABLE I. KNOWLEDGE BASE TABLE




  Knowledge Acquisition




     Knowledge Base




                                                                      4.3 Inference Engine
                                                                          The inference engine is charged with the role of
     Inference Engine                         User Interface          performing and controlling inference on the knowledge
                                                                      base. Specific features of the inference engine depend on
                                                                      the knowledge representation scheme used for the
                                                                      knowledge base. Because the most common
   Figure 3. Architecture of Avian Influenza (H5N1) Expert System
                                                                      representation scheme is production rules, this inference
                                                                      engine will be exemplified. In this research we use
4.1 Knowledge acquisition                                             forward chaining inference engine using Dempster-
    In the present work, knowledge has been obtained                  Shafer Theory. The following will be shown the
from two sources. We acquired textual information from                inference engine using Dempster-Shafer Theory to
literature such as extension booklets, reports, papers, etc.,         diagnose avian influenza.
related to the avian influenza diseases. The printed                  Symptoms:
material allowed became familiar with the subject and a               1. Depression
more effective communication with the experts. Most                   2. Combs, wattle, bluish face region
knowledge was acquired from the experts using                         3. Swollen face region
conventional interviewing techniques. The interview                   4. Narrowness of eyes
methods permitted a better understanding of the problem               5. Balance disorder
and its further representation. This knowledge was
provided by experts on avian influenza. Unstructured                  A. Symptom 1
and structured interviews were used. The unstructured                     Depression is a symptom of Avian Influenza (AI),
interviews were used to define the familiar tasks involved            Newcastle Disease (ND), Fowl Cholera (FC), Infectious
in the process of identification, to obtain an initial                Bronchitis respiratory form (IBRespi), Infectious
understanding of the range of complications involved,                 Bronchitis reproduction form (IBRepro), and Swollen
and to define specific problems for later discussion. The             Head Syndrome (SHS). The measures of uncertainty,
questions were more or less spontaneous and notes were                taken collectively are known in Dempster-Shafer Theory
taken on discussion. These methods were complemented                  terminology as a ``basic probability assignment'' (bpa).



ISSN:2088-5520                                                        C2-95
International Conference on Informatics for Development 2011 (ICID 2011)


Hence we have a bpa, say m1 of 0.7 given to the focal                    0.747  0.153
                                                               m5 (AI) =                0.9
element {AI, ND, FC, IBRespi, IBRepro, SHS} in                               1 0
example, m1({AI, ND, FC, IBRespi, IBRepro, SHS}) =                                0.0581  0.0249
0.7, since we know nothing about the remaining                 m5 (AI, ND, FC) =                   0.083
                                                                                       1 0
probability it is allocated to the whole of the frame of the
                                                               m5 (AI, ND, FC, IBRespi, IBRepro, SHS) =
discernment in example, m1({AI, ND, FC, IBRespi,
                                                               0.0119
IBRepro, SHS}) = 0.3, so:                                               0.0119
m1{AI, ND, FC, IBRespi, IBRepro, SHS} = 0.7                     1 0
m1{Θ} = 1 - 0.7 = 0.3                                    (5)
                                                                           0.0051
                                                               m5 (Ө) =            0.0051
                                                                            1 0                                       (9)
B. Symptom 2
   Combs, wattle, bluish face region are symptoms of           D. Symptom 4
Avian Influenza with a bpa of 0.9, so that:                        Narrowness of eyes is a symptom of Swollen Head
m2{AI} = 0.9                                                   Syndrome with a bpa of 0.9, so that:
m2 {Θ} = 1 – 0.9 = 0.1                              (6)        m6 (SHS) = 0.9
   With the symptoms comb, wattle, bluish face region          m6 (Θ) = 1 – 0.9 = 0.1                              (10)
then required to calculate the new bpa values for some             With narrowness of eyes in the absence of symptoms
combinations (m3). Combination rules for the m3 can be         then required to recalculate the new bpa values for each
seen in the Table II.                                          subset with bpa m7. Combination rules for m7 can be seen
                                                               in Table IV.
     TABLE II. COMBINATION OF SYMPTOM 1 AND SYMPTOM 2
                                                                TABLE IV. COMBINATION OF SYMPTOM 1, SYMPTOM 2, SYMPTOM 3,
                                                                                    AND SYMPTOM 4




            0.63  0.27
m3 (AI) =                0.9
               1 0

                                              0.07
m3 (AI, ND, FC, IBRespi, IBRepro, SHS) =            0.07
                                              1 0
                                                                             0.01071  0.00459
                                                               m7 (SHS) =                         0.13270
m3 (Θ) =
         0.03
               0.03                                                         1  (0.81  0.0747)
         1 0                                           (7)
                                                                                   0.09
                                                               m7 (AI) =                        0.78057
C. Symptom 3                                                               1  (0.81  0.0747)
    Swollen face region is a symptom of            Avian
                                                                                           0.0083
Influenza, Newcastle Disease, Fowl Cholera with a bpa          m7 (AI, ND, FC) =                         0.07199
of 0.83, so that                                                                    1  (0.81  0.0747)
m4 {AI, ND, FC} = 0.83
m4 (Θ) = 1 – 0.83= 0.17                                (8)     m7 (AI, ND, FC, IBRespi,              IBRepro,   SHS)    =
    With the symptom of swollen face region then                     0.00119
                                                                                    0.01032
required to calculate the new bpa values for each subset.      1  (0.81  0.0747)
Combination rules for the m5 can be seen in Table III.
                                                                                 0.00051
TABLE III. COMBINATION OF SYMPTOM 1, SYMPTOM 2, AND SYMPTOM    m7 (Θ) =                         0.00442
                             3                                             1  (0.81  0.0747)                       (11)

                                                               E. Symptom 5
                                                                   Balance disorders is a symptom of Newcastle
                                                               Diseases and Swollen Head Syndrome with a bpa of 0.6,
                                                               so that:
                                                               m8 {ND,SHS} = 0.6
                                                               m8 {Θ} = 1 - 0.6 = 0.4                          (12)




ISSN:2088-5520                                                 C2-96
International Conference on Informatics for Development 2011 (ICID 2011)


   With balance disorders symptom will be required to           The most highly bpa value is the m9 (AI) that is equal to
recalculate the new bpa values for each subset with m9          0.58725 which means the possibility of a temporary
bpa. Combination rules for the m9 can be seen in Table          diseases with symptoms of depression, comb, wattle,
V.                                                              bluish face region, swollen region face, narrowness of
                                                                eyes, and balance disorders is the Avian influenza
 TABLE V. COMBINATION OF SYMPTOM 1, SYMPTOM 2, SYMPTOM 3,       (H5N1).
                SYMPTOM 4, AND SYMPTOM 5

                                                                4.4 User Interface
                                                                    A user interface is the method by which the expert
                                                                system interacts with a user. The input or output interface
                                                                defines the way in which the expert system interacts with
                                                                the user and other systems such as databases. Interfaces
                                                                are graphical with screen displays, windowing, and
                                                                mouse control. They receive input from the user and
                                                                display output to the user The user interface development
                                                                of Avian Influenza (H5N1) Expert System to begin with
                                                                designing web pages and designing a web-based
                                                                applications. Designing web pages using PHP, the web
                                                                page then connected to the MySQL database, after that
                                                                designing a web-based applications which used to access
              0.07962  0.05308
m9 (SHS) =                       0.24960                       the network database. The relationship between
                 1  0.46834                                    applications with network database has shaped overall
                                                                applications to manage information to be displayed.
              0.31222                                               .
m9 (AI) =                0.58725
            1  0.46834
                                                                               V.     IMPLEMENTATION
               0.04319                                               The following will be shown the working process of
m9 (ND) =                 0.08124                              expert system in diagnosing a case. The consultation
             1  0.46834
                                                                process begins with selecting the symptoms found on the
                   0.00619  0.00265
                                                                list of symptoms. In the cases tested, a known symptoms
m9 (ND, SHS) =                        0.01663                  are depression, comb, wattle, bluish-colored facade
                      1  0.46834                               region, region of the face swollen, eyes narrowed and
                                                                balance disorders. The consultation process and can be
                       0.02880                                  seen in Figure 4.
m9 (AI, ND, FC) =                 0.05417
                     1  0.46834

m9 (AI, ND, FC, IBRespi,             IBRepro,    SHS)       =
  0.00413
             0.00777
1  0.46834

              0.000232
m9 (Θ) =                  0.00025
            1  0.061038                             (13)

   The final result can be seen in Table VI.

                  TABLE VI. FINAL RESULT




                                                                                 Figure 4. Symptoms Selection


                                                                    In the case of depression, comb, wattle and region of
                                                                the face bluish, region of the face swollen, eyes narrowed
                                                                and lachrymal glands swollen. The result of consultation
                                                                is avian influenza with bpa value equal to
                                                                0.587275693312. Figure 5 shows the result of
                                                                consultation.



ISSN:2088-5520                                                  C2-97
International Conference on Informatics for Development 2011 (ICID 2011)


                                                                [2]. A. S. Fauci, “Emerging              and Re-Emerging
                                                                      Infectious Diseases: Influenza as a Prototype of the
                                                                      Host-Pathogen Balancing Act,” Elsevier, Cell, pp.
                                                                      665 -670, 2006.
                                                                [3]. L. D Sims, J. Domenech, C. Benigno, S. Kahn, A.
                                                                      Kamata, J. Lubrouth, V. Martin, and P. Roeder,
                                                                      “Origin and evolution of highly pathogenic H5N1
                                                                      avian influenza in Asia,” The Veterinary Record,
                                                                      pp. 159 – 164, 2006.
                                                                [4]. W. H. Assembly, “Strengthening pandemic-
                                                                      influenza preparedness and response,” Resolution
                                                                      WHA58.5, 2005.
                                                                [5]. E. Azziz-Baumgartner, N. Smith, R. González-
                                                                      Alvarez,       “National       pandemic      influenza
                                                                      preparedness planning,” Influenza and Other
                                                                      Respiratory Viruses, pp. 189 – 196, 2006.
               Figure 5. The Result of Consultation             [6]. Anonim, Lampung in Figures, BPS – Statistics of
                                                                      Lampung Province, BPS, Lampung, 2010.
                                                                [7]. J. Durkin, Expert system: Catalog of applications:
                   VI.     CONCLUSION                                 Intelligent Computer Systems, Inc., Akron, OH.
                                                                      First Edition, 1993.
    Identification of avian influenza can be performed          [8]. J. Durkin, Expert Systems: Design and
using Dempster-Shafer Theory. In this paper we describe               Development, Prentice Hall, Englewood Cliffs,
five symptoms as major symptoms which include                         N.J., 1994.
depression, combs, wattle, bluish face region, swollen          [9]. J. Giarratano, and G. Riley, Expert Systems:
face region, narrowness of eyes, and balance disorders.               Principles and Programming, Fourth Edition.
The simplest possible method for using probabilities to               Boston, MA, Thomson/PWS Publishing Company,
quantify the uncertainty in a database is that of attaching           2004.
a probability to every member of a relation, and to use         [10]. S. Russell, and P. Norvig, Artificial Intelligence: A
these values to provide the probability that a particular             Modern Approach, Prentice Hall, Englewood Cliffs,
value is the correct answer to a particular query. An                 NJ, Second Edition. 2002.
expert in providing knowledge is uncertain in the form of       [11]. E. A. Feigenbaum, “Dendral and Meta-Dendral:
rules with the possibility, the rules are probability value.          Roots of Knowledge Systems and Expert System
The knowledge is uncertain in the collection of basic                 Applications,” Artificial Intelligence 59 (1-2), pp.
events can be directly used to draw conclusions in simple             233 – 240, 1993.
cases, however, in many cases the various events                [12]. J. McDermott, “R1: an expert in the computing
associated with each other. Knowledge based is to draw                system domain,” In Proceedings of the National
conclusions, it is derived from uncertain knowledge.                  Conference on Artificial Intelligence, pp. 269–271,
Reasoning under uncertainty that used some of                         1980.
mathematical expressions, gave them a different                 [13]. E. H. Shortliffe, “Computer-Based Medical
interpretation: each piece of evidence (finding) may                  Consultations: MYCIN,” Elsevier, New York,
support a subset containing several hypotheses. This is a             1976.
generalization of the pure probabilistic framework in           [14]. E. Turban, J. E. Aronson, Decision support systems
which every finding corresponds to a value of a variable              and intelligent systems, sixth Edition (6th ed),
(a single hypothesis). In this research, Avian Influenza              Hongkong: Prentice International Hall. 2001.
(H5N1) Expert System has been successfully identifying         [15]. V. Akbar, T. Sulistyorini, “Expert System for Avian
Avian Influenza diseases and displaying the result of                 Influenza Diagnose using Visual Basic.NET,”
identification process This research can be an alternative            Research Report, Gunadarma University, 2007.
in addition to direct consultation with doctor and to find     [16]. U. Ridwan, “Sistem Pakar Diagnosa Penyakit Avian
out quickly avian influenza (H5N1) disease.                           Influenza pada Unggas Berbasis Web,” Research
                                                                      Report, IPB, 2010.
                                                                [17]. R. Yager, “Reasoning with Uncertainty for Expert
                                                                      Systems,” International Joint Conference on
                                                                      Artificial Intelligence, 1985.
                         REFERENCES
                                                                [18]. A. P. Dempster, “A Generalization of Bayesian
[1]. B. L. Ligon, Avian Influenza Virus H5N1:                         inference,” Journal of the Royal Statistical Society,
     “A    Review of Its History and Information                      pp. 205 – 247, 1968.
     Regarding Its Potential to Cause the Next                  [19]. G. Shafer, A Mathematical Theory of Evidence,
     Pandemic,” Seminars in Pediatric Infectious                      Princeton University Press, New Jersey, 1976.
     Diseases, Elsevier, pp. 326 – 335, 2005.



ISSN:2088-5520                                                 C2-98

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Avian Influenza (H5N1) Expert System using Dempster-Shafer Theory

  • 1. International Conference on Informatics for Development 2011 (ICID 2011) Avian Influenza (H5N1) Expert System using Dempster-Shafer Theory Andino Maseleno, Md. Mahmud Hasan Department of Computer Science, Faculty of Science, Universiti Brunei Darussalam Jalan Tungku Link, Gadong BE 1410, Negara Brunei Darussalam E-mail: andinomaseleno@yahoo.com, mahmud.hasan@ubd.edu.bn Abstract— Based on Cumulative Number of Confirmed challenges with pandemic preparedness as there may be a Human Cases of Avian Influenza (H5N1) Reported to higher death rate in developing countries compared with World Health Organization (WHO) in the 2011 from more developed countries [5]. In this research, we use 15 countries, Indonesia has the largest number death chicken as research object because chicken population because Avian Influenza which 146 deaths. In this has grown very fast in Lampung Province in the 2009, research, the researcher built an Avian Influenza native chicken population around 11,234,890, broiler (H5N1) Expert System for identifying avian influenza population around 15,879,617, layer population around disease and displaying the result of identification 3,327,847. Lampung Province has been divided into 10 process. In this paper, we describe five symptoms as regencies, 204 districts and 2279 villages with area of major symptoms which include depression, combs, 3,528,835 hectare [6]. wattle, bluish face region, swollen face region, Expert System is a computer application of artificial narrowness of eyes, and balance disorders. We use intelligence [7],[9],[10] which contains a knowledge base chicken as research object. Research location is in the and an inference engine [8]. Since such programs attempt Lampung Province, South Sumatera. The researcher to emulate the thinking patterns of an expert, it is natural reason to choose Lampung Province in South that the first work was done in artificial intelligence Sumatera on the basis that has a high poultry circles. Among the first expert systems were the 1965 population. Dempster-Shafer theory to quantify the Dendral programs [11], which determined molecular degree of belief as inference engine in expert system, structure from mass spectrometer data; R1 [12] used to our approach uses Dempster-Shafer theory to configure computer systems; and MYCIN [13] for combine beliefs under conditions of uncertainty and medical diagnosis. The basic idea behind expert system is ignorance, and allows quantitative measurement of simply that expertise, which is the vast body of task- the belief and plausibility in our identification result. specific knowledge, is transferred from a human to a The result reveal that Avian Influenza (H5N1) Expert computer. This knowledge is then stored in the computer System has successfully identified the existence of and users call upon the computer for specific advice as avian influenza and displaying the result of needed. The computer can make inferences and arrive at identification process. a specific conclusion. Then like a human consultant, it gives advices and explains, if necessary, the logic behind Keywords- avian influenza (H5N1), expert system, the advice [14]. Some expert systems for diagnosis in uncertainty, dempster-shafer theory avian influenza have been developed which were expert system for avian influenza disease using Visual Basic.NET [15], and web based [16]. Actually, I. INTRODUCTION according to researchers knowledge, Dempster-Shafer Historically, outbreaks of avian influenza first theory of evidence has never been used for built an expert occurred in Italy in the 1878, when it was a lot of dead system for identifying avian influenza. birds [1]. Then came another outbreak of Avian Influenza The remainder is organized as follows. The in Scotland in the 1959 [2]. The virus that causes Avian uncertainty in expert system is briefly reviewed in Section 2. Section 3 details the proposed Dempster-Shafer Theory. Influenza in Italy and Scotland are the current strain of Architecture of Avian Influenza (H5N1) Expert System in H5N1 virus appeared again attacked poultry and humans Section 4. The experimental results are presented in in various countries in Asia, including Indonesia, which Section 5, and final remarks are concluded in Section 6. caused many deaths in humans [3]. Avian influenza virus H5N1, which has been limited to poultry, now has spread to migrating birds and has II. UNCERTAINTY IN EXPERT SYSTEM emerged in mammals and among the human population. It presents a distinct threat of a pandemic for which the The construction of expert and other intelligent World Health Organization and other organizations are computer systems requires sophisticated mechanism for making preparations. In the 2005, the World Health representing and reasoning with uncertain information. Assembly urged its Member States to develop national At least three forms of uncertainty can be identified as preparedness plans for pandemic influenza [4]. playing a significant role in these types of systems. The Developing countries face particular planning and other first of these possibilistic uncertainty appears in situations ISSN:2088-5520 C2-93
  • 2. International Conference on Informatics for Development 2011 (ICID 2011) where the value of a variable can only be narrowed down related question. The advantages of the Dempster-Shafer to a set of values one of which is the actual value of the theory as follows: variable. The second kind of uncertainty is related to 1. It has the ability to model information in a flexible situations in which there exists uncertainty as to way without requiring a probability to be assigned to satisfaction of a predicate by an element. This is each element in a set, manifested by concepts which have imprecise or gray 2. It provides a convenient and simple mechanism boundaries. A very powerful tool for handling this type (Dempster's combination rule) for combining two or of uncertainty which also handles the first type of more pieces of evidence under certain conditions. uncertainty is the fuzzy set. The third type of uncertainty 3. It can model ignorance explicitly. is related to situations in which the value of a variable 4. Rejection of the law of additivity for belief in disjoint assumes can be modeled by the performance of a random propositions. experiment [17]. Figure 1 shows the process for dealing Avian Influenza (H5N1) Expert System using Dempster- with uncertainty in Avian Influenza (H5N1) Expert Shafer theory in the decision support process. Flowchart System. of Avian Influenza (H5N1) Expert System shown in Figure 1. Step 1 Start Representation of uncertainty Alternative Rule on the set of basic events Yes Input Symptoms m1 (B) m2 (C) Step 2 Step 3 No Merging uncertain information Conclusion m (A) = 1 Figure 1. The process for dealing with uncertainty in Avian Influenza (H5N1) Expert System End In step 1, an expert provides uncertain knowledge in the form of rules with the possibility. These rules are Figure 2. Flowchart of Avian Influenza (H5N1) Expert System probability values. In step 2, the uncertain knowledge on a set of basic events can be directly used to draw The consultation process begins with selecting the conclusions in simple cases (step 3). However, in many symptoms. If there are symptoms then will calculate, The cases the various events associated with each other. Dempster-Shafer theory provides a rule to combine Therefore, it is necessary to combine the information evidences from independent observers and into a single contained in step 1 into the global value system. In step 3, and more informative hint. Evidence theory is based on the goal is knowledge-based systems draw conclusions. It belief function and plausible reasoning. First of all, we is derived from uncertain knowledge in steps 1 and 2, and must define a frame of discernment, indicated by the sign is usually implemented by an inference engine. Working Θ . The sign 2Θ indicates the set composed of all the with the inference engine, the expert can adjust the input subset generated by the frame of discernment. For a that they enter in Step 1 after displaying the results in hypothesis set, denoted by A, m(A)→[0,1]. steps 2 and 3. m( )=0 III. DEMPSTER-SHAFER THEORY (1) ∅ is the sign of an empty set. The function m is the basic The Dempster-Shafer theory was first introduced by probability assignment. Dempster's rule of combination Dempster [18] and then extended by shafer [19], but the combines two independent sets of mass assignments. kind of reasoning the theory uses can be found as far back (∅) = 0 (2) as the seventeenth century. This theory is actually an extension to classic probabilistic uncertainty modeling. (3) Whereas the Bayesian theory requires probabilities for each question of interest, belief functions allow us to base degrees of belief for on question on probabilities for a ISSN:2088-5520 C2-94
  • 3. International Conference on Informatics for Development 2011 (ICID 2011) Where with structured interviews. In the structured interviews, we revised and discussed in depth familiar tasks to clarify (4) questions. 4.2 Knowledge Base A critical aspect of building an expert system is The results are that Avian Influenza (H5N1) Expert formulating the scope of the problem and gleaning from System successfully identifying disease and displaying the source expert the domain information needed to solve the result of identification process. the problem. The reliability of an expert system depends on the quality of knowledge contained in the knowledge base. In this research, we built a Avian Influenza (H5N1) IV. AVIAN INFLUENZA (H5N1) EXPERT Expert System and we describe five symptoms which SYSTEM include depression, combs, wattle, bluish face region, Avian Influenza (H5N1) Expert System has four main swollen face region, narrowness of eyes, and balance architectural components that are the knowledge base, the disorders. Knowledge of which input on the testing of inference engine, the knowledge acquisition module, and this expert system can be seen in Table I. the user interface for input/output. Figure 3 shows architecture of Avian Influenza (H5N1) Expert System. TABLE I. KNOWLEDGE BASE TABLE Knowledge Acquisition Knowledge Base 4.3 Inference Engine The inference engine is charged with the role of Inference Engine User Interface performing and controlling inference on the knowledge base. Specific features of the inference engine depend on the knowledge representation scheme used for the knowledge base. Because the most common Figure 3. Architecture of Avian Influenza (H5N1) Expert System representation scheme is production rules, this inference engine will be exemplified. In this research we use 4.1 Knowledge acquisition forward chaining inference engine using Dempster- In the present work, knowledge has been obtained Shafer Theory. The following will be shown the from two sources. We acquired textual information from inference engine using Dempster-Shafer Theory to literature such as extension booklets, reports, papers, etc., diagnose avian influenza. related to the avian influenza diseases. The printed Symptoms: material allowed became familiar with the subject and a 1. Depression more effective communication with the experts. Most 2. Combs, wattle, bluish face region knowledge was acquired from the experts using 3. Swollen face region conventional interviewing techniques. The interview 4. Narrowness of eyes methods permitted a better understanding of the problem 5. Balance disorder and its further representation. This knowledge was provided by experts on avian influenza. Unstructured A. Symptom 1 and structured interviews were used. The unstructured Depression is a symptom of Avian Influenza (AI), interviews were used to define the familiar tasks involved Newcastle Disease (ND), Fowl Cholera (FC), Infectious in the process of identification, to obtain an initial Bronchitis respiratory form (IBRespi), Infectious understanding of the range of complications involved, Bronchitis reproduction form (IBRepro), and Swollen and to define specific problems for later discussion. The Head Syndrome (SHS). The measures of uncertainty, questions were more or less spontaneous and notes were taken collectively are known in Dempster-Shafer Theory taken on discussion. These methods were complemented terminology as a ``basic probability assignment'' (bpa). ISSN:2088-5520 C2-95
  • 4. International Conference on Informatics for Development 2011 (ICID 2011) Hence we have a bpa, say m1 of 0.7 given to the focal 0.747  0.153 m5 (AI) =  0.9 element {AI, ND, FC, IBRespi, IBRepro, SHS} in 1 0 example, m1({AI, ND, FC, IBRespi, IBRepro, SHS}) = 0.0581  0.0249 0.7, since we know nothing about the remaining m5 (AI, ND, FC) =  0.083 1 0 probability it is allocated to the whole of the frame of the m5 (AI, ND, FC, IBRespi, IBRepro, SHS) = discernment in example, m1({AI, ND, FC, IBRespi, 0.0119 IBRepro, SHS}) = 0.3, so:  0.0119 m1{AI, ND, FC, IBRespi, IBRepro, SHS} = 0.7 1 0 m1{Θ} = 1 - 0.7 = 0.3 (5) 0.0051 m5 (Ө) =  0.0051 1 0 (9) B. Symptom 2 Combs, wattle, bluish face region are symptoms of D. Symptom 4 Avian Influenza with a bpa of 0.9, so that: Narrowness of eyes is a symptom of Swollen Head m2{AI} = 0.9 Syndrome with a bpa of 0.9, so that: m2 {Θ} = 1 – 0.9 = 0.1 (6) m6 (SHS) = 0.9 With the symptoms comb, wattle, bluish face region m6 (Θ) = 1 – 0.9 = 0.1 (10) then required to calculate the new bpa values for some With narrowness of eyes in the absence of symptoms combinations (m3). Combination rules for the m3 can be then required to recalculate the new bpa values for each seen in the Table II. subset with bpa m7. Combination rules for m7 can be seen in Table IV. TABLE II. COMBINATION OF SYMPTOM 1 AND SYMPTOM 2 TABLE IV. COMBINATION OF SYMPTOM 1, SYMPTOM 2, SYMPTOM 3, AND SYMPTOM 4 0.63  0.27 m3 (AI) =  0.9 1 0 0.07 m3 (AI, ND, FC, IBRespi, IBRepro, SHS) =  0.07 1 0 0.01071  0.00459 m7 (SHS) =  0.13270 m3 (Θ) = 0.03  0.03 1  (0.81  0.0747) 1 0 (7) 0.09 m7 (AI) =  0.78057 C. Symptom 3 1  (0.81  0.0747) Swollen face region is a symptom of Avian 0.0083 Influenza, Newcastle Disease, Fowl Cholera with a bpa m7 (AI, ND, FC) =  0.07199 of 0.83, so that 1  (0.81  0.0747) m4 {AI, ND, FC} = 0.83 m4 (Θ) = 1 – 0.83= 0.17 (8) m7 (AI, ND, FC, IBRespi, IBRepro, SHS) = With the symptom of swollen face region then 0.00119  0.01032 required to calculate the new bpa values for each subset. 1  (0.81  0.0747) Combination rules for the m5 can be seen in Table III. 0.00051 TABLE III. COMBINATION OF SYMPTOM 1, SYMPTOM 2, AND SYMPTOM m7 (Θ) =  0.00442 3 1  (0.81  0.0747) (11) E. Symptom 5 Balance disorders is a symptom of Newcastle Diseases and Swollen Head Syndrome with a bpa of 0.6, so that: m8 {ND,SHS} = 0.6 m8 {Θ} = 1 - 0.6 = 0.4 (12) ISSN:2088-5520 C2-96
  • 5. International Conference on Informatics for Development 2011 (ICID 2011) With balance disorders symptom will be required to The most highly bpa value is the m9 (AI) that is equal to recalculate the new bpa values for each subset with m9 0.58725 which means the possibility of a temporary bpa. Combination rules for the m9 can be seen in Table diseases with symptoms of depression, comb, wattle, V. bluish face region, swollen region face, narrowness of eyes, and balance disorders is the Avian influenza TABLE V. COMBINATION OF SYMPTOM 1, SYMPTOM 2, SYMPTOM 3, (H5N1). SYMPTOM 4, AND SYMPTOM 5 4.4 User Interface A user interface is the method by which the expert system interacts with a user. The input or output interface defines the way in which the expert system interacts with the user and other systems such as databases. Interfaces are graphical with screen displays, windowing, and mouse control. They receive input from the user and display output to the user The user interface development of Avian Influenza (H5N1) Expert System to begin with designing web pages and designing a web-based applications. Designing web pages using PHP, the web page then connected to the MySQL database, after that designing a web-based applications which used to access 0.07962  0.05308 m9 (SHS) =  0.24960 the network database. The relationship between 1  0.46834 applications with network database has shaped overall applications to manage information to be displayed. 0.31222 . m9 (AI) =  0.58725 1  0.46834 V. IMPLEMENTATION 0.04319 The following will be shown the working process of m9 (ND) =  0.08124 expert system in diagnosing a case. The consultation 1  0.46834 process begins with selecting the symptoms found on the 0.00619  0.00265 list of symptoms. In the cases tested, a known symptoms m9 (ND, SHS) =  0.01663 are depression, comb, wattle, bluish-colored facade 1  0.46834 region, region of the face swollen, eyes narrowed and balance disorders. The consultation process and can be 0.02880 seen in Figure 4. m9 (AI, ND, FC) =  0.05417 1  0.46834 m9 (AI, ND, FC, IBRespi, IBRepro, SHS) = 0.00413  0.00777 1  0.46834 0.000232 m9 (Θ) =  0.00025 1  0.061038 (13) The final result can be seen in Table VI. TABLE VI. FINAL RESULT Figure 4. Symptoms Selection In the case of depression, comb, wattle and region of the face bluish, region of the face swollen, eyes narrowed and lachrymal glands swollen. The result of consultation is avian influenza with bpa value equal to 0.587275693312. Figure 5 shows the result of consultation. ISSN:2088-5520 C2-97
  • 6. International Conference on Informatics for Development 2011 (ICID 2011) [2]. A. S. Fauci, “Emerging and Re-Emerging Infectious Diseases: Influenza as a Prototype of the Host-Pathogen Balancing Act,” Elsevier, Cell, pp. 665 -670, 2006. [3]. L. D Sims, J. Domenech, C. Benigno, S. Kahn, A. Kamata, J. Lubrouth, V. Martin, and P. Roeder, “Origin and evolution of highly pathogenic H5N1 avian influenza in Asia,” The Veterinary Record, pp. 159 – 164, 2006. [4]. W. H. Assembly, “Strengthening pandemic- influenza preparedness and response,” Resolution WHA58.5, 2005. [5]. E. Azziz-Baumgartner, N. Smith, R. González- Alvarez, “National pandemic influenza preparedness planning,” Influenza and Other Respiratory Viruses, pp. 189 – 196, 2006. Figure 5. The Result of Consultation [6]. Anonim, Lampung in Figures, BPS – Statistics of Lampung Province, BPS, Lampung, 2010. [7]. J. Durkin, Expert system: Catalog of applications: VI. CONCLUSION Intelligent Computer Systems, Inc., Akron, OH. First Edition, 1993. Identification of avian influenza can be performed [8]. J. Durkin, Expert Systems: Design and using Dempster-Shafer Theory. In this paper we describe Development, Prentice Hall, Englewood Cliffs, five symptoms as major symptoms which include N.J., 1994. depression, combs, wattle, bluish face region, swollen [9]. J. Giarratano, and G. Riley, Expert Systems: face region, narrowness of eyes, and balance disorders. Principles and Programming, Fourth Edition. The simplest possible method for using probabilities to Boston, MA, Thomson/PWS Publishing Company, quantify the uncertainty in a database is that of attaching 2004. a probability to every member of a relation, and to use [10]. S. Russell, and P. Norvig, Artificial Intelligence: A these values to provide the probability that a particular Modern Approach, Prentice Hall, Englewood Cliffs, value is the correct answer to a particular query. An NJ, Second Edition. 2002. expert in providing knowledge is uncertain in the form of [11]. E. A. Feigenbaum, “Dendral and Meta-Dendral: rules with the possibility, the rules are probability value. Roots of Knowledge Systems and Expert System The knowledge is uncertain in the collection of basic Applications,” Artificial Intelligence 59 (1-2), pp. events can be directly used to draw conclusions in simple 233 – 240, 1993. cases, however, in many cases the various events [12]. J. McDermott, “R1: an expert in the computing associated with each other. Knowledge based is to draw system domain,” In Proceedings of the National conclusions, it is derived from uncertain knowledge. Conference on Artificial Intelligence, pp. 269–271, Reasoning under uncertainty that used some of 1980. mathematical expressions, gave them a different [13]. E. H. Shortliffe, “Computer-Based Medical interpretation: each piece of evidence (finding) may Consultations: MYCIN,” Elsevier, New York, support a subset containing several hypotheses. This is a 1976. generalization of the pure probabilistic framework in [14]. E. Turban, J. E. Aronson, Decision support systems which every finding corresponds to a value of a variable and intelligent systems, sixth Edition (6th ed), (a single hypothesis). In this research, Avian Influenza Hongkong: Prentice International Hall. 2001. (H5N1) Expert System has been successfully identifying [15]. V. Akbar, T. Sulistyorini, “Expert System for Avian Avian Influenza diseases and displaying the result of Influenza Diagnose using Visual Basic.NET,” identification process This research can be an alternative Research Report, Gunadarma University, 2007. in addition to direct consultation with doctor and to find [16]. U. Ridwan, “Sistem Pakar Diagnosa Penyakit Avian out quickly avian influenza (H5N1) disease. Influenza pada Unggas Berbasis Web,” Research Report, IPB, 2010. [17]. R. Yager, “Reasoning with Uncertainty for Expert Systems,” International Joint Conference on Artificial Intelligence, 1985. REFERENCES [18]. A. P. Dempster, “A Generalization of Bayesian [1]. B. L. Ligon, Avian Influenza Virus H5N1: inference,” Journal of the Royal Statistical Society, “A Review of Its History and Information pp. 205 – 247, 1968. Regarding Its Potential to Cause the Next [19]. G. Shafer, A Mathematical Theory of Evidence, Pandemic,” Seminars in Pediatric Infectious Princeton University Press, New Jersey, 1976. Diseases, Elsevier, pp. 326 – 335, 2005. ISSN:2088-5520 C2-98