2. We are working to disrupt the healthcare industry
through wearable technology .
3. HUiNNO is a new innovative Blood Pressure Monitor that can be worn on your
wrist to instantaneously detect blood pressure, heart rate, ECG, and more
6. Hypertension (High BP) is a leading cause of stroke, heart attack, de
mentia, kidney failure, etc.
PROBLEM
406,351
total death
(2007)
1
death in every
1.3
minute
7. If you can continuously be aware of
Blood Pressure to manage and
control hypertension,
you can significantly reduce risk of
life-threatening complications
[1] Jeffrey J. Goldberger, Michael E. Cain, Stefan H. Hohnloser, Alan H. Kadish, Bradley P. Knight, Michael S. Lauer, Barry J. Maron, Richard L.
Page, Rod S. Passman, David Siscovick, William G. Stevenson, Douglas P. Zipes, “American Heart Association/American College of Cardiology
Foundation/Heart Rhythm Society Scientific Statement on Noninvasive Risk Stratification Techniques for Identifying Patients at Risk for Sudden
Cardiac Death”, Circulation 2008, pp. 1497-1518, 2009.
9. BP Monitors are very difficult and inconvenient to use
PROBLEM
All current devices are
• PRESSURE & CUFF BASED
• VERY SLOW
• CAN’T USE CONTINUOUSLY
• UNCOMFORTABLE
• INACCURATE
10. Lots of things can mess up your blood pressure
PROBLEM
Cause BP can appear higher by[2,3]
A full bladder 10 – 15 mmHg
An unsupported back 5 – 10 mmHg
Unsupported feet 5 – 10 mmHg
Crossed legs 2 – 8 mmHg
Cuff over clothing 10 – 40 mmHg
Unsupported arm 10mmHg
A conversation or is talking 10 - 15 mmHg
[1] http://www.ama-assn.org/ama/pub/ama-wire/ama-wire/post/doctor-quickly-improved-patients-blood-pressure-readings
[2] Pickering, et al. Circulation 2005
[3] O’Brien, et al. Blood Press Mon. 2002
13. INSTANT BLOOD PRESSURE
HIGHLY ACCURATE
CONVENIENT
1-seconds to measure BP
Provide up to 94% accuracy via
combining biometrics (ECG + PTT + SpO2 )
No cuffs or pressures to measure
continuous and accurate BP
CIRCLO by HUiNNO
14. 50 subject clinic trial at Pusan National University hospital
Provide BP measurement up to
94% Accuracy
via combining biometrics ( ECG + PTT + SpO2 )
95%+ accuracy receives
Grade A
from BHS (British Hypertension Society)
17. Cuff-free measurement of blood pressure using PTT[1]
Latest Researches On Wearable BPMs
Offline analysis comprised
(1) the automatic extraction of PTT values from ECG and
PPG signals,
(2) the evaluation of the ST and MT device accuracy by
comparison of estimated and reference BP values.
Through the calibration step, the parameters mS/mD and qS/qD of the systolic/diastolic
linear models were estimated in each subject.
[1] Masè M, Mattei W, Cucino R, Faes L, Nollo G., “Feasibility of cuff-free measurement
of systolic and diastolic arterial blood pressure.,” J Electrocardiol. 2011 Mar, Vol. 44, No.
2, pp 201-207
18. Cuff-free measurement of blood pressure using PTT
- MIT Media lab
- Specification: Using PTT
- Inventors: Jae-Geol Cho, etc
- Original Assignee: Samsung Electronics
- Section: Human Necessities
- Classification: Medical Or Veterinary Science; Hygiene
- Specification: Method and apparatus for cufflessly and
non-invasively measuring wrist blood pressure in
association with communication device
Latest Researches On Wearable BPMs
19. HUiNNO vs Other Wearable BPMs
1) ECG - Electrocardiogram
2) SpO2 - Saturation of peripheral Oxygen
Developer Parameter Accurate Instant Continuous
Biofeedback
Platform
Visi Mobile Oscillation
Withings Oscillation
Bpro PPG
Samsung
Electronics
PTT
MIT
Prototype
PTT
OUR
DEVICE
ECG1)
+ PTT + SpO2
2)
20. Wearables Are Totally Failing [WIRED.com]
As of September 30, there were 266
wearable devices on the market [1]
[1] http://www.wired.com/2014/11/where-fitness-trackers-fail/
Smart Watches
21. Wearables Are Totally Failing [WIRED.com]
Wearable medical devices are currently a $2.8b market
and will grow 25% p.a. by 2019 to $8.3b[1].
[1] http://mordorintelligence.com/product/global-wearable-market-growth-trends-and-forecasts-2014-2019/
$2.8 B
2014
$8.3 B
2019
Smart Watches
22. Wearable devices can’t measure Blood Pressure
Smart Watches
All of the wearable devices are focusing more on healthcare,
but no device can measure the most vital sign:
BLOOD PRESSURE
24. $1.2
Billion
in 2015
103Million
Hypertensive Patients
Blood Pressure monitoring market to
grow to 1.2 Billion USD in 2015
(HIS Media Group 2013)
32.5% of adults in the U.S.
over 20 suffer from hypertension
(M brain trend monitor 2014.02)
Blood Pressure Monitor + Smart Watch Market
MARKET
Increase in demand for blood pressure measurement in smart devices
25. DEVICE APP / SERVICE CLOUD PLATFORM
165
80
CUSTOMERS HEALTHCARE
Business Model
Good evening everyone. My name is YJ Gil and I am the CEO of HUiNNO.
At HUiNNO, we are working on innovation of healthcare and humanity.
HUiNNO is a new innovative Blood Pressure Monitor that can be worn on your wrist to instantly, accurately, continuously measure blood pressure at any time, without traditional cuffs.
So, what is first things the doctor check, when you visit to the hospital?
What is one of the most important vital sign?
We can probably all agree, they check the blood pressure first.
Knowing your blood pressure and managing hypertension is very important as you see here.
Having high blood pressure or Hypertension can lead to many different serious complications.
In U.S, approximately every minute, a person dies of hypertension related illness.
A lot of papers and journals on hypertension say the following.
“If you can continuously be aware of Blood Pressure to manage and control hypertension….
The problem is that existing Blood Pressure Monitors cannot measure blood pressure continuously and conveniently.
The current cuffed based devices haven’t been changed over 100 years.
Blood Pressure Monitors are very difficult and inconvenient to use. They can’t be use used continuously and they are very slow in working. And they are also not very accurate.
Lots of things can mess up your blood pressure as you see here. Like crossing your legs or having a full bladder while measuring the blood pressure will affect the results.
I will now explain about our solution.
This device is called CIRCLO.
This smart watch can instantly, accurately and easily measure blood pressure.
So it is very convenient to use.
It is very accurate because we use multiple biometric to estimate blood pressure in real time.
Compared to other invasive blood pressure monitor, CIRCLO is accurate for 94%.
I discovered this algorithm during my Ph.D course. This technology is for which I received my Ph.D.
Let’s now compare CIRCLO with competitors.
There have been studies which outline the development of non-invasive blood pressure monitoring system since mid 2000.
This paper proves the highest level of feasibility when PTT(Pulse Transit Time) is used to measure blood pressure.
This proves the co-relation between blood pressure and a reciprocal of PTT.
The left picture that you see here is a prototype system for measuring blood pressure using PTT.
On the right you see a patent of Samsung Electronics, also using PTT.
As you can see, our technology is unlike any other competitors.
We use 3-biometrics to measure blood pressure while the others have only one biometric. So therefore we are very accurate.
A report in Wired says that the number of wearable devices on the market counts 266 as of September 30, 2014.
But these wearable devices are totally failing the people who need them most.
It also says that “So who made a long-term commitment to measuring and tracking their health? People with two or more chronic diseases. According to a Research Survey, 45% of US adults are dealing with at least one chronic condition.”
So Wearables should more focus on chronic patients like high blood pressure patients and Diabetics.
Unfortunately, wearable devices cannot measure Blood Pressure.
Until now Wearable devices for chronic patients could not be found.
Now about the market…
32.5% of US adults over their 20’s suffer from hypertension. Proximately 13% of these people are serious hypertension patients. They need to control their health by measuring their blood pressure every day.
Statistically it shows that blood pressure monitoring market will grow up to 1.2BUSD in 2015.
Our business model is represented on this slide.
Consumers can buy our device from retail shop or online.
Initial App will be provide for free.
However for more analysis data and connectivity, we will charge premium cost.
Our milestone is represented on this slide.
In June last year, we finalized the incorporation in US. And in December 2014, we developed the working mock-up. Our plan for the second quarter of 2015 will be the FDA Approval. And in 4th quarter of the year, we plan to launch globally our product.
