1. Curriculum Vitae – Yu Zhou, Ph.D.
7/6/2015
Contact information:
Office P.O. Box 8054
Department of Anesthesiology
Washington University School of Medicine
660 South Euclid Avenue
St. Louis, MO 63110
Home: 10823 Chase Park Lane, Apt. C
St. Louis, MO 63141
Telephone: (314) 800-8187 (Mobile)
(314) 362-8559 (Office)
Email: zhouy@wustl.edu
Professional Experience::
Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO
Instructor 2010 - present
Postdoctoral Associate 2005 - 2010
Education:
State University of New York at Buffalo, Buffalo, N.Y.
Ph.D. in Neuroscience 2005
Zhejiang University, Hangzhou, Zhejiang, China,
M.S. in Biophysics 1999
Wuhan University, Wuhan, Hubei, China,
B.S. in Biochemistry 1996
Professional Societies and Organizations:
Biophysical Society
Society for Neuroscience
2. Yu Zhou, Ph. D. Curriculum Vitae, p. 2
7/6/2015
Honors and Awards:
Zhejiang University Guanghua Scholoar's Award 1997
Bibliography:
1. Zhou, Y. (corresponding author), Xia, X.-M., Lingle, C.J. Cadmium-cysteine coordination in the BK
inner pore region and its structural and functional implications, Proc Natl Acad Sci U S A. 2015 Apr 6.
pii: 201500953;
2. Zhou, Y. and Lingle, C.J. Paxilline inhibits BK channels by an almost exclusively closed channel block
mechanism, Journal of General Physiology 2014; 144:415-440 (commented by Dr. McManus and Dr.
Rothberg);
3. Brenker, C., Zhou, Y., Müller, A., Echeverry, FA.,Trötschel, C., Poetsch, A., Xia, XM., Bönigk, W.,
Lingle, CJ., Kaupp, UB., Strünker, T., The Ca2+
-activated K+
current of human sperm is mediated by
Slo3, eLife, 2014 Mar 26;3:e01438. doi: 10.7554/eLife.01438.;
4. Zhou, Y., Zeng, X.-H., and Lingle, C.J. Barium ions selectively activate BK channels via the Ca2+
-bowl
site. Proc Natl Acad Sci U S A. 2012 Jul 10; 109(28):11413-8;
5. Yang, C., Zeng, X.-H., Zhou, Y., Xia, X.-M., and Lingle, C.J. LRRC52, a testis-specific auxiliary
subunit of the alkalization-activated Slo3 channel. Proc Natl Acad Sci U S A. 2011 Nov 29;
108(48):19419-24;
6. Zhou, Y. (corresponding author), Xia, X.-M., and Lingle, C.J. Cysteine scanning and modification
reveal major differences between BK channels and Kv channels in the inner pore region. Proc Natl
Acad Sci U S A. 2011 Jul 19; 108(29):12161-6;
7. Zhou, Y. (corresponding author), Xia, X.-M., and Lingle, C.J. Inhibition of large-conductance Ca2+
-
activated K+
channels by nanomolar concentrations of Ag+
. Molecular Pharmacology 2010
Nov;78(5):952-60;
8. Zhou, Y., Tang, Q.-T., Xia, X.-M., and Lingle, C.J. Glycine311, a determinant of paxilline block in BK
channels: a novel bend in the BK S6 helix. Journal of General Physiology 2010; 135:481-94;
9. Zhang, Z., Zhou, Y., Ding, J.-P., Xia, X.-M., and Lingle, C.J. A limited access compartment between
the pore domain and cytosolic domain of the BK channel. Journal of Neuroscience 2006; 26:11833-
11843.
10. Zhou, Y., Auerbach A. Gating reaction mechanisms for NMDA receptor channels. Journal of
Neuroscience 2005; 25:7914-23
11. Zhou, Y., Pearson J.E., Auerbach A. Phi-value analysis of a linear, sequential reaction mechanism:
theory and application to ion channel gating. Biophys. J. 2005; 89:3680-5 (commented by Dr.
Colquhoun);
12. Shen Y., Zhou Y., Yang XL. Characterization of AMPA receptors on isolated amacrine-like cells in
carp retina. Eur. J. Neurosci. 1999; 11:4233-40;
Peer Reviews:
ACS Chemical Biology
Biophysical Journal
3. Yu Zhou, Ph. D. Curriculum Vitae, p. 3
7/6/2015
Journal of General Physiology
Pflügers Archiv European Journal of Physiology
4. Yu Zhou, Ph. D. Curriculum Vitae, p. 4
7/6/2015
References:
1. Professor Christopher Lingle
Washington University, School of Medicine
St. Louis, MO 63110
Email: clingle@wustl.edu
Office Phone: 314-362-8558
FAX: 314-362-8571
2. Professor Joseph Henry Steinbach
Washington University, School of Medicine
St. Louis, MO 63110
Email: jhs@wustl.edu
Office Phone: 314-362-8560
FAX: 314-362-8571
3. Professor Anthony Auerbach
Center for Single Molecule Biophysics
State University of New York at Buffalo
Department Of Physiology and Biophysics
324 Cary Hall, South Campus
3435 Main Street
Buffalo, NY 14214
Email: auerbach@buffalo.edu
Office Phone: 716-829-2435
FAX: 716-829-2569
