1. VICTOR V. OZOLS
3060 North Ridgecrest, House #179, Mesa, AZ 85207
vozols@cox.net (480) 518-5216
SUMMARY
Over 20 years of laboratory research experience in oncology, Parkinson’s disease, cystic fibrosis, Alzheimer’s
disease, veterinary pharmaceuticals, multiple sclerosis, and juvenile diabetes. Looking for a career-oriented
position in which my management, education, and research skills will be fully utilized, as well as enhanced.
PROFESSIONAL EXPERIENCE
Phoenix Children’s Hospital- 3/12 – 7/15
University of Arizona College of Medicine- Phoenix
Department of Neurosciences/Neuro-Oncology, Phoenix, AZ
Senior Research Technologist and Laboratory Manager
- Manage a new research laboratory focusing on the study of atypical teratoid rhabdoid tumor
- Identification of potential drugs/compounds for the study and analysis of AT/RT
- Development of a novel vaccine for the treatment of AT/RT
- Coordination and implementation of murine and canine studies for AT/RT vaccine trials
- Next-generation sequencing and analysis of AT/RT
St. Joseph’s Hospital and Medical Center- 5/05 – 1/12
Barrow Neurological Institute, Phoenix, AZ
Clinical Mass Spectrometry and Neuro-Proteomics Laboratory
Senior Research Technologist and Laboratory Core Manager
- Established, developed, and managed both a new clinical mass spectrometry and neuro-
proteomics core laboratories for the hospital
- Developed and transferred existing radio-immunoassay for 25OH Vitamin D to a new novel
LC/ESI-Ion Trap mass spectrometry 25OH Vitamin D2/D3 assay
- Analyzed and reported all clinic patient samples for 25OH Vitamin D2/D3 as a core facility for the
hospital
- Identified known and novel proteins-peptides using MALDI-TOF/TOF mass spectrometry and
LC/ESI-Ion Trap mass spectrometry analysis in Parkinson’s and other neurodegenerative diseases
Mayo Clinic College of Medicine 7/03 – 2/05
Department of Biochemistry and Molecular Biology, Scottsdale, AZ
Research Technologist II
- Identification of potential drugs for the treatment of cystic fibrosis by developing a high-
throughput screening assay to detect the appearance of F508 CFTR at the cell surface
- Studied trafficking and turnover of mature wild type and mutant CFTR in the endocytic pathway
- Retroviral and adenoviral expression of CFTR and mutant variants in polarized epithelial cells to
study the turnover of the proteins in a more physiologically-relevant system
- Mass protein production in mammalian cells for crystallization and x-ray structure determination

2. Victor V. Ozols 2
Mayo Clinic College of Medicine 5/02 – 6/03
Laboratory of Molecular Neurobiology, Jacksonville, FL
Special Project Associate
- Identification of candidate compounds in the treatment of Alzheimer’s disease
- Examination of nonsteroidal anti-inflammatory (NSAIDs) effects on amyloid precursor protein
(APP) metabolism
- Behavioral testing of transgenic mouse models of Alzheimer’s disease and amyloid beta (A)
modulating compounds
- MALDI-TOF mass spec analysis of protein species in transgenic mouse models
- Purification of the APP complex from in vitro systems
Heska Corporation, Fort Collins, Colorado 7/93 – 9/01
Pharmaceutical Research Group
Science Technologist II
- Identification of candidate compounds for potential use in a flea and tick control product
- Identification and purification of recombinant antigens for the development of flea and tick
vaccines in canines and felines
- Identification, characterization, and purification of candidate parasite antigens for the use in both
heartworm diagnostics and vaccine development for canines and felines
- In vivo Feline/Canine vaccine trials
- Produce cat fleas on a mass scale for the flea vaccine and flea allergy projects
- Management of 25-30 part-time employees
Synergen, Inc., Boulder, Colorado 11/91 – 4/93
Department of Neuroscience
Research Associate
- Discover and purify a remyelination factor for multiple sclerosis
- Further quantify potential in vitro based factors in the study of Parkinson's disease
Barbara Davis Center for Childhood Diabetes- 5/89 – 11/91
University of Colorado Health Sciences Center, Denver, Colorado
Professional Research Associate
- Development and maintenance of murine islet-specific T-cell clones
- Identification and characterization of islet cell antigens
AMC Cancer Research Center, Denver, Colorado 8/87 – 5/89
Research Assistant
- Tumor cell fusion in order to study tumor development, progression, and diversity
PEER-REVIEWED PUBLICATIONS
1. Madhavi Chakravadhanula, Victor Ozols, Chris N. Hampton, Parth Chodavadia, Li Zhou, Daniel
Catchpoole, Matthew Huentelman, Anat Erdreich-Epstein, Ratan D. Bhardwaj. Wnt pathway in
atypical teratoid rhabdoid tumors. Neuro-Oncology. (2014) Sept. 21:1-10.

3. Victor V. Ozols 3
2. Chakravadhanula M., Ozols V.V., Hampton C.N., Zhou L., Catchpoole D., Bhardwaj R.D.
Expression of the HOX genes and HOTAIR in atypical teratoid rhabdoid tumors and other
pediatric brain tumors. Cancer Genetics. (2014) Sept; 207(9): 425-428.
3. Pingerelli, P.L., Ozols, V.V., Saleem, H., Anderson, C.R., Burns, R.S. The calcium-modulated
structures of calmodulin and S100b proteins are useful to monitor hydrogen/deuterium
exchange efficiency using matrix-assisted laser desorption ionization time-of-flight mass
spectrometry. European Journal of Mass Spectrometry (Chichester, England). (2009)
15(6): 739-746.
4. Kukar, T., Murphy, M.P., Eriksen, J.L., Sagi, S.A., Weggen, S., Smith, T.E., Ladd, T., Khan, M.A.,
Beard, J., Dodson, M., Merit, S., Ozols, V.V., Anastasiadis, P.Z., Das, P., Fauq, A., Koo, E.H., and
Golde, T.E. Diverse compounds mimic Alzheimer’s disease-causing mutations by augmenting
A42 production. Nature Medicine. (2005) May; 11(5): 545-550.
5. Gentzsch, M., Chang, X-B., Cui, L., Wu, Y., Ozols, V.V., Choudhury, A., Pagano, R.E., Riordan, J.R.
Endocytic trafficking routes of wild type and F508 cystic fibrosis transmembrane conductance
regulator. Molecular Biology of the Cell. (2004) Jun; 15(6): 2684-2696.
6. Eriksen, J.L., Sagi, S.A., Smith, T.E., Weggen, S., Das, P., McLendon, D.C., Ozols, V.V.,
Jessing, K.W., Zavitz, K.H., Koo, E.H., Golde, T.E. NSAIDs and enantiomers of flurbiprofen target
-secretase and lower A42 in vivo. Journal of Clinical Investigation. (2003) Aug 1; 112(3):
440-449.
7. Weggen, S., Eriksen, J.L., Ozols, V., McLendon D.C., Golde, T., Koo, E.H. Evidence that
nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation
of -secretase activity. Journal of Biological Chemistry. (2003) Aug 22; 278(34): 31831-31837.
8. Tsuji N., Morales T., Carmody A., Ozols V., Chandrashekar R. Cloning and preliminary
characterization of a novel cuticular antigen from the filarial parasite Dirofilaria immitis.
Parasitology International. (2000) Dec; 49(4): 321-325.
9. Chandrashekar R., Tsuji N., Morales T., Carmody A., Ozols V., Welton J., and Tang L. Removal of
hydrogen peroxide by a 1-cysteine peroxiredoxin enzyme of the filarial parasite Dirofilaria
immitis. Parasitology Research. (2000) Mar; 86(3): 200-206.
10. Tsuji N., Morales T., Ozols V., Carmody A., and Chandrashekar R. Identification of an asparagine
amidohydrolase from the filarial parasite Dirofilaria immitis. International Journal of Parasitology.
(1999) Sept; 29(9): 1451-1455.
11. Tsuji N., Morales T., Ozols V., Carmody A., and Chandrashekar R. Molecular characterization of a
calcium-binding protein from the filarial parasite Dirofilaria immitis. Molecular and Biochemical
Parasitology. (1998) Nov 30; 97(1-2): 69-79.
12. Chandrashekar R., Tsuji N., Morales T., Ozols V., and Mehta K. An ERp60-like protein from filarial
parasite Dirofilaria immitis has both transglutaminase and protein disulfide isomerase activity.
Proceedings of the National Academy of Sciences, USA. (1998) Jan 20; 95(2): 521-536.

4. Victor V. Ozols 4
POSTERS AND ORAL PRESENTATIONS
1. Ozols V., Bhardwaj R.D., Chakravadhanula M. (2015). Study of biomarker RNA in pediatric brain
tumors. Phoenix Children’s Hospital Research Day, Phoenix, AZ (Poster).
2. Kala M., Ozols V., Hampton C., Bhardwaj R.D., Chakravadhanula M. (2015). Sonic hedgehog
pathway as a therapeutic target for atypical teratoid rhabdoid tumor and medulloblastoma type
of pediatric brain tumors. Phoenix Children’s Hospital Research Day, Phoenix, AZ (Poster).
3. Norris, G.A., Hampton, C.N., Ozols, V., Bhardwaj R.D., Chakravadhanula, M. (2015). Targeting
the Hippo signaling pathway in atypical teratoid rhabdoid tumor. Phoenix Children’s Hospital
Research Day, Phoenix, AZ (Poster).
4. Bhardwaj RD, Chakravadhanula M, Ozols V, Hampton C, Yeri A. (2015). Expression of Polycomb
Repressor Complex proteins and miR-181 in atypical teratoid rhabdoid tumors. Epigenetics and
Cancer 2015, Keystone Symposia, Keystone, CO (Poster).
5. Ratan D. Bhardwaj, Victor V. Ozols, Chris N. Hampton, Li Zhou, Daniel Catchpoole, Madhavi
Chakravadhanula. (2014). Expression of HOX genes and HOTAIR in atypical teratoid rhabdoid
tumor and other pediatric brain tumors. 16th
International Symposium on Pediatric Neuro-
Oncology (ISPN), Singapore (Poster).
6. Bhardwaj R.D., Chakravadhanula M., Hampton C., Ozols V., Georges .J, Decker W.K., Kodibagkar
V. (2014). Autologous dendritic cell vaccine to combat brain tumors in mice. 16th
International
Symposium on Pediatric Neuro-Oncology (ISPN), Singapore (Poster).
7. Ratan D. Bhardwaj, Victor V. Ozols, Chris N. Hampton, Li Zhou, Daniel Catchpoole, Madhavi
Chakravadhanula. (2014). Study of miR-21, miR-196, and miR-302 in atypical teratoid rhabdoid
tumors. 16th
International Symposium on Pediatric Neuro-Oncology (ISPN), Singapore (Poster).
8. Madhavi Chakravadhanula, Chris N. Hampton, Victor Ozols, Li Zhou, Daniel Catchpoole, Anat
Erdreich-Epstein, Ratan D. Bhardwaj. (2014). Frizzled1 receptor, a potential therapeutic target
for atypical teratoid rhabdoid tumor. American Association for Cancer Research (AACR),
Philadelphia, PA (Poster).
9. Bhardwaj R.D., Philip Schissler, Chris Levine, Kim Knowles, Scott Plummer, Chakravadhanula M,
Ozols V., Decker WK. (2014). Autologous dendritic cell vaccine to combat brain tumors in dogs
and mice. Phoenix Children’s Hospital Research Day, Phoenix, AZ (Poster).
10. Bhardwaj R.D., Philip Schissler, Chris Levine, Kim Knowles, Scott Plummer, Chakravadhanula M,
Ozols V., Decker WK. (2013). Autologous dendritic cell vaccine to combat brain tumors in dogs
and mice. Society for Neuro-Oncology, San Francisco, CA (Poster).
11. Bhardwaj R.D., Hampton C., Ozols V., Chakravadhanula M. (2013). Analysis of the Wnt5b
signaling pathway to identify novel therapeutics for atypical teratoid rhabdoid tumors. Society
for Neuro-Oncology, San Francisco, CA (Poster and Oral Presentation).

5. Victor V. Ozols 5
12. Sereduk C., Chakravadhanula M., Hampton C., Ozols V., Yin H., Bhardwaj R. (2013). High-
throughput compound screening of atypical teratoid rhabdoid tumor for exploration of possible
novel therapeutic pathways. Translational Genomics Research Institute (TGen) Scientific Retreat,
Phoenix, AZ (Poster).
13. Parth Chodavadia, Madhavi Chakravadhanula, Maya Sarihan, Chris Hampton, Victor Ozols, Ratan
Bhardwaj. (2013). Characterizing Wnt5B ligand-receptor interactions in atypical teratoid
rhabdoid tumor. Helios Education Foundation and the Translational Genomics Research Institute
(TGen) Symposium, Phoenix, AZ (Poster).
14. Peter L. Pingerelli, Haroon Saleem, Victor V. Ozols, Becky K. Duffy, Charles H. Adler, Thomas G.
Beach, Holly Shill, Marwan Sabbagh, John Caviness and Richard S. Burns. (2008). Proteomic
profiling of human ventricular cerebrospinal fluid. 7th
Annual World Congress Human Proteomic
Organization (HUPO), Amsterdam, Netherlands (Poster).
15. Soren A. Burns, Crystal. R. Moran, Peter L. Pingerelli, Victor V. Ozols, and Richard S. Burns.
(2008). Redefining the Lewy body: Evidence of distinct protein composition and nonrandom
assembly process. 12th
International Congress of Parkinson’s Disease and Movement Disorders,
Chicago, IL (Poster).
16. Pingerelli, P.L., Saleem, H., Ozols, V.V., Burns, R.S. (2007). Dimerization of A53T, A30P, and E46k
mutants of -synuclein: Differences in anti-parallel conformation and NAC region interaction.
Society for Neuroscience, San Diego, CA (Poster).
17. Pingerelli, P.L., Ozols, V.V., Anderson, C.R., Burns, R.S. (2007). Ca2+
-dependent deuterium
exchange properties of EF-hand calcium-binding proteins calmodulin and S100 are useful to
monitor MALDI HDX efficiency. 55th
ASMS Conference on Mass Spectrometry, Seattle, WA
(Poster).
18. Burns, S.A., Pingerelli, P.L., Ozols, V.V., and Burns, R.S. (2006). Redefining the Lewy body.
Annals of Neurology, Chicago, IL (Poster; Abstract: Vol 60; Supplement 3, p. S51).
19. Ozols, V.V., Gentzsch, M., Cui, L., Chang, X., Riordan, J.R. (2004). A high-throughput assay for the
direct detection of F508 CFTR at the cell surface. The 18th
Annual North American Cystic Fibrosis
Conference, St. Louis, MO (Poster).
20. Eriksen, J.L., Nicolle, M.M. Prescot, S., Ozols, V.V., Zhuo, J.M., Smith, T.E., Beard, J.L., Weggen, S.,
Sagi, S.A., Koo, E.H., Golde, T.E. (2003). Chronic treatment of transgenic APP mice with
r-Flurbiprofen. Society for Neuroscience, New Orleans, LA (Poster).
21. Sagi, S., Eriksen, J.L., Beard, J., Ozols, V.V., Weggen, S., Smith, T., Koo, E.H., Golde, T.E. (2003).
A42 lowering NSAIDs can be converted into A42 raising agents by simple structural
modifications. Society for Neuroscience, New Orleans, LA (Poster).
22. Eriksen, J.L., McLendon, C., Monnier, T., Weggen, S.A., Ozols, V.V., Fauq, A., Kahn, M., Howard,
V., Koo, E.H., Golde, T.E. (2002). NSAIDs decrease A42 production by direct modulation of
gamma secretase activity. Society for Neuroscience, Orlando, FL (Poster).

6. Victor V. Ozols 6
23. Wisnewski, N., Brandt, K.S., Silver, G.M., Ozols, V.V., Maddux, J.D., Cupp, E., Zang, D., and Cupp, M.
(2001). Expression and purification of recombinant horn fly thrombostasin. 18th
International
Conference of the World Association for the Advancement of Veterinary Parasitology, Stresa, Italy
(Oral Presentation).
24. Chandrashekar R., Morales T., Carmody A., and Ozols V. (2000). Molecular characterization of
CUT-1 like proteins from Dirofilaria immitis. 47th Annual Meeting of the American Society of
Tropical Medicine and Hygiene, Houston, TX (Poster).
25. Chandrasheka R., Tsuji N., Morales T., Ozols V., and Mehta K. (1997). Cloning and functional
expression of a novel transglutaminase with protein disulfide isomerase activity isolated from the
filarial parasite Dirofilaria immitis. 46th Annual Meeting of the American Society of Tropical
Medicine and Hygiene, Orlando, FL (Oral Presentation; Late Breaker in Molecular Biology).
26. Chandrasheka R., Tsuji N., Morales T., Carmody A., and Ozols V. (1997). Identification of an
asparagine amidohydrolase from Dirofilaria immitis. 46th Annual Meeting of the American
Society of Tropical Medicine and Hygiene, Orlando, FL (Poster; Abstract #535).
27. Tsuji N., Morales T., Carmody A., Ozols V., Welton J., and Chandrasheka R. (1997). Molecular
characterization of a second thioredoxin peroxidase from Dirofilaria immitis. 46th Annual
Meeting of the American Society of Tropical Medicine and Hygiene, Orlando, FL (Poster; Abstract
#538).
28. Thomas R.E., Ozols V., Hausser N., and Silver G.M. (1997). The biology of cat fleas,
Ctenocephalides felis, reared on an in vitro feeding system. Fourth International Symposium on
Ectoparasites of Pets, University of California, Riverside, CA (Oral Presentation).
29. Thomas R.E., Wallenfels L., Ozols V., and Popiel I. (1995). Assessment of cat flea survival and
fecundity on cats using a novel chambered flea technique. Third International Symposium on
Ectoparasites of Pets. College Station, TX (Poster; Abstract, p. 115).
30. Ozols V., Thomas R.E., and Popiel I. (1994). The use of an artificial feeding system for the mass
production of fleas and as an in vitro bioassay. Rocky Mountain Conference of Parasitologists,
Colorado Springs, CO (Oral Presentation).
31. McDonald J.R., Crawford F., Huettl P., Ozols V., and McManaman J. (1992). Growth factor
expression during demyelination and remyelination of the adult mouse CNS. Gordon Research
Conference on Myelin, Holderness School, NH (Poster).
32. McDonald J.R., Crawford F., Huettl P., Ozols V., and McManaman J. (1992). Growth factor
expression during demyelination and remyelination of the adult mouse CNS. Advances in the
Understanding and Treatment of Multiple Sclerosis (IBC), Sheraton Boston Hotel and Towers, MA
(Poster).
33. Lin L.-F., Ross J., Zhang TJ, Lile J., Ozols V., Collins F., and McMamaman J. (1992). Characterization
of native (as opposed to recombinant) GDNF. Aspen Lodge Symposium, Estes Park, CO (Poster).

7. Victor V. Ozols 7
34. Stecha P., Ozols V., Bergman B., and Haskins K. (1991). T cell hybridomas reactive with islet cell
antigens. Journal of Cellular Biochemistry, (Poster; Abstract, Supplement 15A, C516).
EDUCATION
B.A. (Biology), University of Colorado, Boulder, CO 1985
Emphasis: Molecular/Cellular Biology