1. Sarah Fox-Greer Resume Page 1
RESUME
SARAH FOX-GREER
Ph.D, BSc (HONS)
2356 Fenton Parkway Apt 305
San Diego, 92108
Email: sarahfox4689@gmail.com
Cell: 619 384 4581
PERSONAL INFORMATION
 Nationality: British
 Date of Birth: 6th February 1983
 Permanent resident of the USA
PROFILE
 Over a decade of lab experience with particular expertise in pharmacology, inflammation biology,
and immunology.
 Diligent, data driven scientist that works well independently and in team settings.
 Looking for an industrial scientist position where my strong knowledge base and technical
expertise can be used to advance drug discovery.
 Productive and collaborative scientist with a proven track record of publishing data (see attached
publication list).
LABORATORY SKILLS
 Isolation and culture of primary human and murine cells (PBMCs, neutrophils, intestinal
organoids). Immune cell, intestinal and lung cell line culture, bacterial culture.
 Cell Transfection (siRNA, luciferase reporter assays).
 Multi-color flow cytometry, ELISA, Western Blot, confocal imaging, myography,
Electroparamagnetic resonance (EPR), electrochemical detection.
 In vivo - intra-tracheal and intra-peritoneal administration of drugs, harvesting of tissues,
preparation of tissues for histology
RESEARCH EXPERIENCE
2011 – Present University of California, San Diego
Post-Doctoral Researcher – Department of Pathology
 Consequences of Apoptotic Epithelial Cell Engulfment in the Gastrointestinal Tract.
I am investigating the pathology of IBD with a particular focus on the engulfment of apoptotic
cells of the GI tract by phagocytes and the how this process can influence the progression and
resolution of inflammation. Work in this lab has identified a potential pathway involved in
determining macrophage inflammatory responsiveness during apoptotic cell clearance.

2. Sarah Fox-Greer Resume Page 2
 Teaching and Training: I have mentored various undergraduate students and volunteers in
the lab, teaching basic lab skills as well as project planning, troubleshooting and data
presentation. I attended the AAI advanced immunology course in Boston in 2013.
2008 – 2011 University of Edinburgh
Post-Doctoral Researcher – Centre for Inflammation Research
 CDK inhibitor Drugs as a Novel Class of Anti-Inflammatory Therapeutics.
Working under the supervision of Professor Rossi, I investigated the pharmacological effects
of CDK inhibitor drugs on granulocyte and macrophage function and the potential of these
drugs as therapeutics for chronic inflammatory diseases.
 Teaching: I mentored two undergraduate students during their honours projects and helped
out on assessment panels (student presentations) for the Pharmacology honours course.
2007 (Sep) – 2007 (Dec) University of Edinburgh
Data Collection - Research Assessment Exercise.
 I worked alongside Professor Seckl in the run up to the submission of the Research
Assessment Exercise (RAE) results for the University of Edinburgh. I helped gather and mine
the data for official submission. The university gained a five star rating for the medical
departments following this assessment.
2004 – 2007 University of Edinburgh
PhD- ‘ Cation Exchanged Zeolites as Novel Storage Materials of Nitric Oxide;
Therapeutic Potential in Biomedical Applications ‘
Supervisors; Professor Adriano G Rossi and Professor Ian L Megson.
 The clinical applications of novel nitric oxide (NO) releasing zeolites (a micro-porous
material) were investigated to examine the potential of these materials as biocompatible
coatings for medical devices. Work during my PhD led to the publication of a number of
papers and due to the nature of the results, provoked interest form the national press.
Industrial Experience- March 2004 – September 2004 Quintiles UK Ltd.
Placement Student – Cardiovascular Pharmacology; Telemetry Dept.
 I worked for 6 months in a contract research organization where I gained valuable industrial
experience, working to GLP standards on drug safety studies within a large department. My
honours project involved validating a system to monitor animal activity to complement
telemetry data.
 Techniques: Study planning and design, Good laboratory practice skills (GLP), animal
handling and data analysis.
SUMMARY OF QUALIFICATIONS
 PhD 2004 - 2008 “Cation Exchanged Zeolites as Novel Storage Materials of
Nitric Oxide; Therapeutic Potential in Biomedical Applications”. University of
Edinburgh.
 BSc (HONS) 2000 - 2004 Pharmacology with Industrial Experience. 1st
Class.
University of Edinburgh.

3. Sarah Fox-Greer Resume Page 3
REFEREES
Dr Peter Ernst
University of California, San Diego
Department of Pathology,
9500 Gilman Drive,
San Diego,
92093
Tel: 858.534.2975
Email – pernst@ucsd.edu
Dr Soumita Das
University of California, San Diego
Department of Pathology,
9500 Gilman Drive,
San Diego,
92093
Tel: 858 822 5523
Email – sodas@ucsd.edu
Professor Adriano Rossi
Queen’s Medical Research Institute,
Centre for Inflammation Research,
47 Little France Crescent,
Edinburgh,
EH16 4TJ
Tel: +44 0131 242 6659
Email – A.G.Rossi@ed.ac.uk

4. Sarah Fox-Greer Resume Page 4
PUBLICATIONS
Original Research Articles.
Das S, Sarkar A, Sinha Choudhury S, Owen KA, Castillo V, Fox S, Eckmann L, Elliott MR, Casanova JE, Ernst PB.
ELMO1 has an essential rolein the internalization of Salmonella Typhimurium intoenteric macrophages that
impacts disease outcome CMGH. (2015) accepted for publication in May edition.
Fox S, Ryan, KA, Berger AH, Petro K, Das S, Crowe SE, Ernst PB. The role of C1q in recognition of apoptotic
epithelial cells and inflammatory cytokine production by phagocytes during Helicobacter pylori infection.
(Revisions Submitted).
Fox S, Das S, Den Hartog C, Smith P, Crowe SE, Ernst PB. Activation of AMPK in Macrophages; Insights into
apoptotic cell induced macrophage anergy. (in preparation).
Das S, Sarkar A, Ryan KA, Fox S, Berger AH, Juncadella IJ, Bimczok D, Smythies LE, Harris PR, Ravichandran KS,
Crowe SE, Smith PD, Ernst PB. Brain angiogenesis inhibitor 1 is expressed by gastric phagocytes during
infection withHelicobacter pyloriand mediates the recognition and engulfment of human apoptotic gastric
epithelial cells. FASEB J. (2014) May;28(5):2214-24.
Marwick JA, Dorward DA, Lucas CD, Jones KO, Sheldrake TA, Fox S, Ward C, Murray J, Brittan M, Hirani N, Duffin
R, Dransfield I, Haslett C, Rossi AG. Oxygen Levels Determine the Ability of Glucocorticoids to Influence
Neutrophil Survival in Inflammatory Environments. J Leukoc Biol (2013) Dec 94(6):1285-92
Lucas CD, Dorward DA, Tait MA, Fox S, Marwick JA, Allen KC, Robb CT, Hirani N, Haslett C, Duffin R, Rossi AG.
Downregulation of Mcl-1 has anti-inflammatory pro-resolution effects and enhances bacterial clearance from the lung.
Mucosal Immunol. 2014 Jul;7(4):857-68.
Shaw CA, Taylor EL, Fox S, Megson IL, Rossi AG. Differential Susceptibility to Nitric Oxide-Evoked Apoptosis in
Human Inflammatory Cells. Free Radical Biology and Medicine (2011) Jan 1;50(1):93-101.
Leitch AE, Riley NA, Sheldrake TA, Festa M, Fox S, Duffin R, Haslett C, Rossi AG. The cyclin-dependent kinase
inhibitor R-roscovitine down-regulates Mcl-1 to override pro-inflammatory signalling and drive neutrophil
apoptosis. European Journal of Immunology, (2010) Apr;40(4):1127-38.
Fox, S, Wilkinson, T.S, Wheatley P.S, Morris R.E. Xiao B, Barlow PG, Simpson AJ, Sutherlnd, A, Butler A.R Megson I.L,
Rossi A.G. NO-loaded Zn2+-exchanged zeolite materials: A potential bifunctional anti-bacterial strategy. Acta
Biomaterialia (2010) Apr;6(4):1515-21.
Duffin R, Leitch AE, Sheldrake TA, Hallet JM, Mayer C, Fox S, Alessandri AL, Martin MC, Brady HJ, Teixeira MM,
Dransfield I, Haslett C, Rossi AG. The CDK Inhibitor R-roscovitine, Promotes Eosinophil Apoptosis by Down-
regulation of Mcl-1. FEBS Letters (2009) 583, 15 2540-2546.
Turnbull CM, Marcarino P, Sheldrake TA, Lazzarato L, Cena C, Fruttero R, Gasco A, Fox S, Megson IL, Rossi AG. A
Novel Hybrid Aspirin-NO-Releasing Compound Inhibits TNFalpha Release from LPS-activated Human
Monocytes and Macrophages. Journal of Inflammation (2008) 5:12.
Xiao B, Wheatley P.S, Zhao X, Fletcher A.J, Fox S, Rossi A.G, Megson I.L, Bordiga S, Regil L, Thomas K.M, Morris R.E.
High-capacity hydrogen and nitric oxide adsorption and storage in a metal-organic framework. Journal of the
American Chemical Society (2007) 129(5): 1203-12.
Wheatley P.S, Butler A.R, Crane M.S, Fox S, Xiao B, Rossi A.G, Megson I.L, Morris R.E. NO-Releasing Zeolites and
their Antithrombotic Properties. Journal of the American Chemical Society (2006) 128, 502-509.
Review Articles
Fox, S*, Leitch AE*, Duffin R, Haslett C, Rossi AG. Neutrophil Apoptosis, Relevance to the Innate Immune
Response and Inflammatory Disease. Journal of Innate Immunity, (2010) 2(3):216-27 .
Duffin R, Leitch AE, Fox S, Haslett C, Rossi AG. Targeting Granulocyte Apoptosis: mechanisms, models and
therapies. Immunological Reviews (2010) 236, 26-40.
Book Chapter
Fox S, Rossi AG. Chapter 8 “The Macrophage” Pages 96-107. Fundamentals of Inflammation. Editors Charlie Serhan,
Peter Ward and Derek Gilroy, Medicine and Life Sciences Cambridge University Press, ISBN 9780521887298.
* Joint 1st authorship.