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Chemistry-The center of
Science
Dr. V. Sivamurugan
Assistant Professor
PG & Research Department of Chemistry
E mail: sivaatnus@gmail.com
Mobile: 9444316582
This portrayal shows an alchemist’s workshop circa 1580.
“Can we name one thing in our daily life, which
is not the result of chemical developments?
No, chemistry made its tremendous
contributions, making our life better, more
convenient and pleasurable”
-Attila Pavlath
ACS President 2001
Chemistry Other sciences
Why Chemistry is the Central Science?
We are looking at molecular level
Anti-bacterial
Anti-fungal
?
Molecules 2014, 19, 6929-6940;
doi:10.3390/molecules19066929
Electronic Age
Chemistry is Fundamental Science
Chemistry and othersciences
CHEMISTRY BIOLOGY
BIO-
CHEMISTRY
CHEMISTRY PHYSICS
PHYSICO-
CHEMICAL
Chemical analysis of the components of living organisms
that may explain their biological functionality.
Study the structure and physical properties of matter,
laws of chemical interaction and the theories involved
CHEMISTRY
AGRICULT
URE
EDAFOLOGY
CHEMISTRY MEDICINE
PHARMACOL
OGY
CHEMISTRY PETROLIUM
PETROCHEMI
STRY
Science that studies the soils. It’s mineral composition
and production of chemical fertilizers
Science that studies the origin, actions and properties
of chemical substances in living organisms
Study of oil and its natural and synthetic derivatives
Why Study Chemistry?
 Everyone and everything around us
involves chemistry – explains our world
 What in the world is n’t Chemistry?
 Helps you make choices; helps make you a
better informed citizen
 A possible career for your future
 Used to attain a specific goal
How mobile phones made?
Medical Testing and Disease Diagnostics
Evolution of personal monitoring
• Simplified at-home test kits facilitate the personal monitoring of human health. For
example, diabetic patients once had to visit a laboratory to determine if sugar was
present in their urine.
• In 1941, Miles Laboratories introduced the first convenient sugar-in-urine assay for
home use. Although difficult to develop, dip-and-read urine tests were finally
introduced in 1956.
• In the 1960s, the first portable, battery-operated blood glucose meter was introduced
to work with chemical sticks to detect the glucose, considerably improving the quality
of life for diabetic patients.
• In the 1970s and 1980s, home-use diagnostic kits for fecal occult blood, ovulation,
pregnancy, and strep were introduced.
Cancer Chemotherapy
Evolution of cancer chemotherapy
• The use of chemicals to treat cancer (cancer chemotherapy) began in 1942 with the
clinical use of nitrogen mustards by Louis S. Goodman and Alfred Gilman.
• Subsequent discoveries included mechlorethamine (Mustargen), chlorambucil (1952),
and cyclophosphamide (1956). Drugs which block folic acid (also called
antimetabolites) were also developed.
• Aminopterin (1947) was effective against leukemia, but its adverse effects on white
blood cells quickly led to its replacement by methotrexate.
• In the 1950s, George Hitchings and Charles Heidelberger developed the
antimetabolitic mercaptopurine for leukemia and Fluorouracil for gastrointestinal and
breast tumors.
Artificial limbs and medical devices
• Modern artificial limbs and organs,
replacement joints, contact lenses
and hearing aids, and biomaterials
which are crafted from specialized
plastics and other high-tech
materials have all been produced
through chemistry.
• By manipulating the structures of
molecules and creating new ones,
chemists and engineers have
developed new medical materials
that are strong, flexible, and
durable.
• A few such medical devices include
the 1945 artificial kidney, the 1950s
prosthetic heart valves, and the 1982
surgical implantation of a permanent
artificial heart.
• Plastic contact lenses were
introduced in 1956, and soft bifocal
contacts were refined in 1985.
Artificial heart
Artificial
heart
valves
Novel Healthcare Materials
Chemistry Far and Wide
Norman Borlaug
 Nobel Peace Prize
 Presidential Medal of
freedom
 Congressional Gold
Medal
 Father of the Green
Revolution
 Credited with saving
over 1 billion people
from starvation
Agriculture
Crop Protection and Pest Managament
DDT and pesticides
 Pesticides shield agricultural
crops from harm by fungi,
insects, and competition
from other plants.
 In 1939, Paul Mueller
developed the inexpensive
insecticide DDT (dichlor-
diphenyl-trichlorethan) to
control potato beetles and
other insects.
 Today’s low-application
pesticides provide greater
economy for farmers, added
worker safety, and are more
environmentally friendly
than ever before.
Thinned egg-
shells caused by
DDT
DDT in combating
malaria
Crop Protection and Pest Managament
Livestock protection
• In 1881, Louis Pasteur
successfully perfected techniques
to vaccinate animals in order to
induce immunity against the
anthrax-causing organism.
• In 1981, the anti-parasitic
Ivermectin was introduced to fight
a wide range of mites, worms, and
other internal parasites that effect
animal health.
• Current research is attempting to
prevent bovine spongiform
encephalopathy (BSE), the so
called `mad cow disease’ that is
believed to be caused by proteins
in animal feed that harbor the
infectious agent.
Louis
Pasteur
Pasteur vaccinates animals
Food analysis
 Organophosphorous most popular pesticide
 Most commonly used organophosphorous: QUINALPHOS (O,O diethyl-o-
quinoxalinly phosphorothioate)
Quinalphos +H2O2 peroxophosphonate
Peroxophosphonate+ luminol 3aminophthalate anion*
3-aminophthalate* 3-aminophthalate +
observed emission
Food analysis
Food Processing - Handling and Safety
The roots of food chemistry go back to the
German Justus Liebig, who first made meet
extract at the middle of nineteenth century.
Advances in preservation and
manufacturing techniques have allowed us
to create processed foods. As food
chemistry fueled industrial practices, many
processed foods were developed. New
technologies also extended the shelf life of
food, including freeze-drying (liophilisation)
(1906), deep-freezing foods (1920),
precooking frozen foods (1939), and making
concentrates from fluids (1946).
The one-time placard of
Liebig’s meat extract
Preservation and manufacturing advances
Food Processing - Handling and Safety
Food safety and testing
Any raw agricultural product or prepared
food can be contaminated and adversely
affect human health. Contaminations may
occur during preparation, cooking, serving
and storage. Chemical advances that
increase food safety include rapid test
methods which enable the detection
ofmicrobial food contaminants and control
of food-borne epidemics. Illnesses from the
most common food-borne pathogens have
been reduced by 20% from 1997 to 1999 in
the USA.
Food Storing
Food packaging
Packaging food with plastics, metal,
glass, and ceramic technologies help to
preserve food during sale, shipping, and
preparation. Ralph Wiley invented
industrial saran polymer in the 1930s,
and household Saran wrap was
introduced in 1953 to provide an
excellent barrier to oxygen, moisture,
aroma, and chemicals under extreme
humidity and temperature conditions.
Saran wrap is a copolymer of vinylidene
chloride and vinyl chloride. Other
innovations include utilization of
aluminum cans for foods and beverages
(1960s), and of PET (polyethylene
terephthalate) as recyclable container
packaging to replace glass or aluminum
(1970s).
Food Storing
Refrigerants and chlorofluorocarbons
Since it was introduced for home use in
1918, refrigeration has altered food
preservation by providing the ability to
transport and store fresh foods safely. Early
1920s refrigerators were unpopular after the
sulfur dioxide coolant proved toxic. The
solution was Freon 12, a chlorofluorocarbon
(also referred to as a CFC, CCl2F2)
compound made into a refrigerant gas by
Thomas Midgley and Charles Kettering in
1931. Refrigerators quickly became
standard in homes, restaurants, and
grocery stores. Freon’s role is now being
discontinued because of its role in the
destruction of the earth’s ozone layer.
Icebox (1890) and
household refrigerator by Kelvinator
(1926)
Forensic Science
A trail of blood made visible with the use of
the reagent luminol.
Forensic science
 Chemiluminescence is used by criminalists to
detect traces of blood at crime scene
 Solution: luminol powder (C8H7O3N3),
hydrogen peroxide, and a hydroxide (eg.
KOH) sprayed where blood might found
 Tiny amount of iron from Hb in blood serves
as catalyst for the chemiluminescence
reaction, luminol to glow
Innovations in Electronics
Evolution of consumer electronics
• Electronic materials and
microelectronic devices are the
heart of countless modern
products, such as CD players,
televisions, computers, digital
cameras and wireless devices.
• From vacuum tubes to transistors
to integrated circuits, chemical
engineers have made electronics
smaller, more powerful, energy-
efficient, and cheaper. New
materials, processes for
producing highly purified
materials.
Innovations in Electronics
Advanced synthetic materials
• Consumer electronics, cellular
phones, and personal computers
rely on though, durable, non-
conducting plastics to protect
sensitive electronic components.
• Plastics are essential in electronic
applications because of their
insulating properties;
• By manipulating the structures of
molecules and creating new ones,
chemists and engineers produce
new materials that are both strong
and flexible.
• These advances have improved
impact resistance, reduced the
total weight of equipment, and
reduced the cost of consumer
goods.
Innovations in Electronics
• It was the tiny, reliable
electronic component called a
transistor.
• The transistor and the
subsequent integrated circuits
(that contains millions of
transistors) served as the
foundation for the
development of modern
electronics.
Transistors
The inventors
of transistor
The first
transistor
green chemistry
It means producing the chemicals of our daily
needs using such reactions and chemical
processes which neither use toxic chemicals
nor emit such chemicals into the atmosphere.
Our focus
Nano chemistry
Clean and Green energy: Fuel Cell
“LIFE WITHOUT
CHEMISTRY, WE WOULD
BE BACK TO THE STONE
AGE”
Thank you all

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Chemistry-The center of Science

  • 1. Chemistry-The center of Science Dr. V. Sivamurugan Assistant Professor PG & Research Department of Chemistry E mail: sivaatnus@gmail.com Mobile: 9444316582
  • 2. This portrayal shows an alchemist’s workshop circa 1580.
  • 3. “Can we name one thing in our daily life, which is not the result of chemical developments? No, chemistry made its tremendous contributions, making our life better, more convenient and pleasurable” -Attila Pavlath ACS President 2001 Chemistry Other sciences
  • 4. Why Chemistry is the Central Science?
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  • 8. We are looking at molecular level Anti-bacterial Anti-fungal ? Molecules 2014, 19, 6929-6940; doi:10.3390/molecules19066929
  • 11. Chemistry and othersciences CHEMISTRY BIOLOGY BIO- CHEMISTRY CHEMISTRY PHYSICS PHYSICO- CHEMICAL Chemical analysis of the components of living organisms that may explain their biological functionality. Study the structure and physical properties of matter, laws of chemical interaction and the theories involved
  • 12. CHEMISTRY AGRICULT URE EDAFOLOGY CHEMISTRY MEDICINE PHARMACOL OGY CHEMISTRY PETROLIUM PETROCHEMI STRY Science that studies the soils. It’s mineral composition and production of chemical fertilizers Science that studies the origin, actions and properties of chemical substances in living organisms Study of oil and its natural and synthetic derivatives
  • 13. Why Study Chemistry?  Everyone and everything around us involves chemistry – explains our world  What in the world is n’t Chemistry?  Helps you make choices; helps make you a better informed citizen  A possible career for your future  Used to attain a specific goal
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  • 18. Medical Testing and Disease Diagnostics Evolution of personal monitoring • Simplified at-home test kits facilitate the personal monitoring of human health. For example, diabetic patients once had to visit a laboratory to determine if sugar was present in their urine. • In 1941, Miles Laboratories introduced the first convenient sugar-in-urine assay for home use. Although difficult to develop, dip-and-read urine tests were finally introduced in 1956. • In the 1960s, the first portable, battery-operated blood glucose meter was introduced to work with chemical sticks to detect the glucose, considerably improving the quality of life for diabetic patients. • In the 1970s and 1980s, home-use diagnostic kits for fecal occult blood, ovulation, pregnancy, and strep were introduced.
  • 19. Cancer Chemotherapy Evolution of cancer chemotherapy • The use of chemicals to treat cancer (cancer chemotherapy) began in 1942 with the clinical use of nitrogen mustards by Louis S. Goodman and Alfred Gilman. • Subsequent discoveries included mechlorethamine (Mustargen), chlorambucil (1952), and cyclophosphamide (1956). Drugs which block folic acid (also called antimetabolites) were also developed. • Aminopterin (1947) was effective against leukemia, but its adverse effects on white blood cells quickly led to its replacement by methotrexate. • In the 1950s, George Hitchings and Charles Heidelberger developed the antimetabolitic mercaptopurine for leukemia and Fluorouracil for gastrointestinal and breast tumors.
  • 20. Artificial limbs and medical devices • Modern artificial limbs and organs, replacement joints, contact lenses and hearing aids, and biomaterials which are crafted from specialized plastics and other high-tech materials have all been produced through chemistry. • By manipulating the structures of molecules and creating new ones, chemists and engineers have developed new medical materials that are strong, flexible, and durable. • A few such medical devices include the 1945 artificial kidney, the 1950s prosthetic heart valves, and the 1982 surgical implantation of a permanent artificial heart. • Plastic contact lenses were introduced in 1956, and soft bifocal contacts were refined in 1985. Artificial heart Artificial heart valves Novel Healthcare Materials
  • 21. Chemistry Far and Wide Norman Borlaug  Nobel Peace Prize  Presidential Medal of freedom  Congressional Gold Medal  Father of the Green Revolution  Credited with saving over 1 billion people from starvation Agriculture
  • 22. Crop Protection and Pest Managament DDT and pesticides  Pesticides shield agricultural crops from harm by fungi, insects, and competition from other plants.  In 1939, Paul Mueller developed the inexpensive insecticide DDT (dichlor- diphenyl-trichlorethan) to control potato beetles and other insects.  Today’s low-application pesticides provide greater economy for farmers, added worker safety, and are more environmentally friendly than ever before. Thinned egg- shells caused by DDT DDT in combating malaria
  • 23. Crop Protection and Pest Managament Livestock protection • In 1881, Louis Pasteur successfully perfected techniques to vaccinate animals in order to induce immunity against the anthrax-causing organism. • In 1981, the anti-parasitic Ivermectin was introduced to fight a wide range of mites, worms, and other internal parasites that effect animal health. • Current research is attempting to prevent bovine spongiform encephalopathy (BSE), the so called `mad cow disease’ that is believed to be caused by proteins in animal feed that harbor the infectious agent. Louis Pasteur Pasteur vaccinates animals
  • 24. Food analysis  Organophosphorous most popular pesticide  Most commonly used organophosphorous: QUINALPHOS (O,O diethyl-o- quinoxalinly phosphorothioate)
  • 25. Quinalphos +H2O2 peroxophosphonate Peroxophosphonate+ luminol 3aminophthalate anion* 3-aminophthalate* 3-aminophthalate + observed emission Food analysis
  • 26. Food Processing - Handling and Safety The roots of food chemistry go back to the German Justus Liebig, who first made meet extract at the middle of nineteenth century. Advances in preservation and manufacturing techniques have allowed us to create processed foods. As food chemistry fueled industrial practices, many processed foods were developed. New technologies also extended the shelf life of food, including freeze-drying (liophilisation) (1906), deep-freezing foods (1920), precooking frozen foods (1939), and making concentrates from fluids (1946). The one-time placard of Liebig’s meat extract Preservation and manufacturing advances
  • 27. Food Processing - Handling and Safety Food safety and testing Any raw agricultural product or prepared food can be contaminated and adversely affect human health. Contaminations may occur during preparation, cooking, serving and storage. Chemical advances that increase food safety include rapid test methods which enable the detection ofmicrobial food contaminants and control of food-borne epidemics. Illnesses from the most common food-borne pathogens have been reduced by 20% from 1997 to 1999 in the USA.
  • 28. Food Storing Food packaging Packaging food with plastics, metal, glass, and ceramic technologies help to preserve food during sale, shipping, and preparation. Ralph Wiley invented industrial saran polymer in the 1930s, and household Saran wrap was introduced in 1953 to provide an excellent barrier to oxygen, moisture, aroma, and chemicals under extreme humidity and temperature conditions. Saran wrap is a copolymer of vinylidene chloride and vinyl chloride. Other innovations include utilization of aluminum cans for foods and beverages (1960s), and of PET (polyethylene terephthalate) as recyclable container packaging to replace glass or aluminum (1970s).
  • 29. Food Storing Refrigerants and chlorofluorocarbons Since it was introduced for home use in 1918, refrigeration has altered food preservation by providing the ability to transport and store fresh foods safely. Early 1920s refrigerators were unpopular after the sulfur dioxide coolant proved toxic. The solution was Freon 12, a chlorofluorocarbon (also referred to as a CFC, CCl2F2) compound made into a refrigerant gas by Thomas Midgley and Charles Kettering in 1931. Refrigerators quickly became standard in homes, restaurants, and grocery stores. Freon’s role is now being discontinued because of its role in the destruction of the earth’s ozone layer. Icebox (1890) and household refrigerator by Kelvinator (1926)
  • 30. Forensic Science A trail of blood made visible with the use of the reagent luminol.
  • 31. Forensic science  Chemiluminescence is used by criminalists to detect traces of blood at crime scene  Solution: luminol powder (C8H7O3N3), hydrogen peroxide, and a hydroxide (eg. KOH) sprayed where blood might found  Tiny amount of iron from Hb in blood serves as catalyst for the chemiluminescence reaction, luminol to glow
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  • 33. Innovations in Electronics Evolution of consumer electronics • Electronic materials and microelectronic devices are the heart of countless modern products, such as CD players, televisions, computers, digital cameras and wireless devices. • From vacuum tubes to transistors to integrated circuits, chemical engineers have made electronics smaller, more powerful, energy- efficient, and cheaper. New materials, processes for producing highly purified materials.
  • 34. Innovations in Electronics Advanced synthetic materials • Consumer electronics, cellular phones, and personal computers rely on though, durable, non- conducting plastics to protect sensitive electronic components. • Plastics are essential in electronic applications because of their insulating properties; • By manipulating the structures of molecules and creating new ones, chemists and engineers produce new materials that are both strong and flexible. • These advances have improved impact resistance, reduced the total weight of equipment, and reduced the cost of consumer goods.
  • 35. Innovations in Electronics • It was the tiny, reliable electronic component called a transistor. • The transistor and the subsequent integrated circuits (that contains millions of transistors) served as the foundation for the development of modern electronics. Transistors The inventors of transistor The first transistor
  • 36. green chemistry It means producing the chemicals of our daily needs using such reactions and chemical processes which neither use toxic chemicals nor emit such chemicals into the atmosphere. Our focus
  • 38. Clean and Green energy: Fuel Cell
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  • 40. “LIFE WITHOUT CHEMISTRY, WE WOULD BE BACK TO THE STONE AGE”
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Editor's Notes

  1. To be able to make conscious decisions in everyday life. (battery acid baking soda) DO YOU LIKE A NEW CAR SMELL? Organic compounds breaking down.