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Ultrasound Research in 2018
PUTTING OURSELVES
OUT OF A JOB
NIK THEYYUNNI @HEYDRNIK #BRF18
CONFLICT OF INTEREST
No personal disclosures
NIK THEYYUNNI @HEYDRNIK #BRF18
GE research Funding
NIK THEYYUNNI @HEYDRNIK #BRF18
NIK THEYYUNNI @HEYDRNIK #BRF18
NIK THEYYUNNI @HEYDRNIK #BRF18
Ultrasound Research in 2018
PUTTING OURSELVES
OUT OF A JOB
NIK THEYYUNNI @HEYDRNIK #BRF18
EVERYONE should do
ultrasound… EVERYONE
NIK THEYYUNNI @HEYDRNIK #BRF18
Teach EVERYONE to do
ultrasound…
EVERYONE
NIK THEYYUNNI @HEYDRNIK #BRF18
Make it so EASY to do ultrasound
that everyone does it
NIK THEYYUNNI @HEYDRNIK #BRF18
EVERYONE DO ULTRASOUND
• Showcase innovative educational
methods
• Gamification
NIK THEYYUNNI @HEYDRNIK #BRF18
NIK THEYYUNNI @HEYDRNIK #BRF18
NIK THEYYUNNI @HEYDRNIK #BRF18
NIK THEYYUNNI @HEYDRNIK #BRF18
Make it so EASY to do ultrasound
that everyone does it
NIK THEYYUNNI @HEYDRNIK #BRF18
AUTOMATION?
NIK THEYYUNNI @HEYDRNIK #BRF18
AUTOMATION
• Piecemeal
• Tedious tasks first
• Tasks that are hard for people
NIK THEYYUNNI @HEYDRNIK #BRF18
AUTOMATION
Acquisition is hard
NIK THEYYUNNI @HEYDRNIK #BRF18
AUTOMATION
Start with interpretation
NIK THEYYUNNI @HEYDRNIK #BRF18
AUTOMATED IVC
NIK THEYYUNNI @HEYDRNIK #BRF18
NIK THEYYUNNI @HEYDRNIK #BRF18
AUTOMATED IVC
Fung et al. Algorithm-Based Automated Inferior Vena Cava Diameter Tracking Correlates With Physician Performed Measurements.
Presented at AIUM 2016
NIK THEYYUNNI @HEYDRNIK #BRF18
AUTOMATION
• Tedious tasks first
• Tasks that are hard for people
NIK THEYYUNNI @HEYDRNIK #BRF18
TTE EXCELLENCE: VTI
NIK THEYYUNNI @HEYDRNIK #BRF18
NIK THEYYUNNI @HEYDRNIK #BRF18
NIK THEYYUNNI @HEYDRNIK #BRF18
NIK THEYYUNNI @HEYDRNIK #BRF18
AUTOMATION
Acquisition is hard
NIK THEYYUNNI @HEYDRNIK #BRF18
PROTOTYPE SENSOR
NIK THEYYUNNI @HEYDRNIK #BRF18
29
Step 1:
VR sensor applied
to patients neck by
nurse
Step 3:
VR Monitor
automates
measurements and
records trend for
physician
Step 2:
VR algorithms
extract
measurements
NIK THEYYUNNI @HEYDRNIK #BRF18
NIK THEYYUNNI @HEYDRNIK #BRF18
PROTOTYPE SENSOR
NIK THEYYUNNI @HEYDRNIK #BRF18
Cindy H. Hsu, MD, PhD
Assistant Professor
Department of Emergency
Medicine & Surgery
March 2nd, 2018
Automated
extracranial
internal carotid
artery ultrasound
sensor for TBI
NIK THEYYUNNI @HEYDRNIK #BRF18
Center Position
100 ml/min
200 ml/min
Left Position4 mm phantom
NIK THEYYUNNI @HEYDRNIK #BRF18
PROTOTYPE SENSOR
NIK THEYYUNNI @HEYDRNIK #BRF18
NIK THEYYUNNI @HEYDRNIK #BRF18
NIK THEYYUNNI @HEYDRNIK #BRF18
PUT ME OUT OF A JOB
NIK THEYYUNNI @HEYDRNIK #BRF18

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Putting ourselves out of a job: Ultrasound Research in 2018 by Nikhil Theyyunni, MD

Editor's Notes

  1. Rather than presenting one specific research project today I want to give you an overview – a more global sense - of some of the things we’re doing, and what I think our research program builds towards. And I want to talk a little bit about research we do that’s really unique to our program. I want you to keep in the back of your mind as I go our overarching goal with out research
  2. Which is to put ourselves out of a job. My goal is, by the time I retire, they won’t need to replace me. We don’t have airway directors, some day we might not need US directors. So how do we do that? US is a complex skill, we spend a lot of resources right now to teach our residents how to scan. How do we get from here to no need for me? Well lets talk research
  3. This one is chocolate. And this is a big part of how we make me obsolete. If EVERYONE knows ultrasound, why have an US director? It needs to be in the water
  4. This one is chocolate. And this is a big part of how we make me obsolete. If EVERYONE knows ultrasound, why have an US director?
  5. This one is chocolate. And this is a big part of how we make me obsolete. If EVERYONE knows ultrasound, why have an US director?
  6. Motivating people to learn. Some of you have participated or seen some of the game based US teaching we do, and we work on research with that as well, this year I was involved in a manuscript talking about Sonoslam We do some of this – lets teach EVERYONE todo ultrasound We do a lot of educational work. Strain of our research is figuring out how to get everyone educated. Some of that is defining what they need to be taught would be familiar to the med ed/MERG people and done in collaboration with them – The Delphi method
  7. Sonogames We’ve worked with national colleagues to set up an educational endevour called sonoslam focused on gamifiying ultrasound education for students. Showcase novel educational methods Gameification
  8. We use phantoms and more advanced simulators or normal live models to both educate and assess students knowledge. This picture is one of the teams using an advanced model that simulates transvaginal ultrasound – a procedure that’spretty rare for students to get access to, gamification spurs our competitive edges
  9. I think if
  10. This one is chocolate. And this is a big part of how we make me obsolete. If EVERYONE knows ultrasound, why have an US director?
  11. People still need to do the scans, how can we reduce the barriers to do each of these things? Automate automate, automate. We don’t count our own cells anymore, how much of our own ultrasound will we do in 10 years
  12. We do this elsewhere! Noone uses a microscope anymore! Maybe some ultrasound applications can be fully or partially automated. If EVERYONE does ultrasound, and we can automate some of the harder/tedious/technical parts, maybe that takes us the rest of the way. What I’m about to show you is where I think U of M has a unique chance to make out mark
  13. We do this elsewhere! Noone uses a microscope anymore! Maybe some ultrasound applications can be fully or partially automated. If EVERYONE does ultrasound, and we can automate some of the harder/tedious/technical parts, maybe that takes us the rest of the way. What I’m about to show you is where I think U of M has a unique chance to make out mark So pick an area where acquisition could conceivably be much easier to start with. The Neck has great windows and lots of stuff to look at
  14. We do this elsewhere! Noone uses a microscope anymore! Maybe some ultrasound applications can be fully or partially automated. If EVERYONE does ultrasound, and we can automate some of the harder/tedious/technical parts, maybe that takes us the rest of the way. What I’m about to show you is where I think U of M has a unique chance to make out mark So pick an area where acquisition could conceivably be much easier to start with. The Neck has great windows and lots of stuff to look at
  15. Manuscript submitted for publication
  16. We do this elsewhere! Noone uses a microscope anymore! Maybe some ultrasound applications can be fully or partially automated. If EVERYONE does ultrasound, and we can automate some of the harder/tedious/technical parts, maybe that takes us the rest of the way. What I’m about to show you is where I think U of M has a unique chance to make out mark
  17. Further and further beyond the basics.
  18. We do this elsewhere! Noone uses a microscope anymore! Maybe some ultrasound applications can be fully or partially automated. If EVERYONE does ultrasound, and we can automate some of the harder/tedious/technical parts, maybe that takes us the rest of the way. What I’m about to show you is where I think U of M has a unique chance to make out mark So pick an area where acquisition could conceivably be much easier to start with. The Neck has great windows and lots of stuff to look at
  19. This is our platform, can use it for different things
  20. Target Product Profile Description of product that will eventually be sold Anticipated Feature/Benefits - (Performance level required for clinical and commercial success) 1) Clearly articulate the clinical workflow process. 2) Describe your Envisioned Product. A wireless ultrasound-based disposable smart sensor patch that nurses can quickly and easily place on the side of a patient’s neck with little training to provide continuous volume responsiveness trending. How do you expect this to get commercialized after Coulter funding? Initially form a company and raise angel capital as well as SBIR/STTR funding Ultimately exit through sale of company - Form a new company and raise venture capital/angel $, or - Direct license to a revenue generating company Speak to Jack Miner – venture center
  21. Early success with this platform, for our TBI research project ct here is the sensor quantifying blood flow in a phantom model. I can’t get into the secret sauce thaty makes this work, but it’s not using doppler, and it’s a promising new way for us to get at this problem.
  22. This is our platform, can use it for different things