The document discusses research into automating ultrasound tasks to make ultrasound easier to perform. It proposes developing easy-to-use ultrasound sensors and automated interpretation of scans to put ultrasound experts like itself out of a job. Specifically, it discusses prototypes for automated measurement of the inferior vena cava and internal carotid artery which could track values and trends without expert involvement. The goal is to develop automated ultrasound that is so simple even non-experts can use it.
My talk from the 2018 Information Architecture Summit in Chicago on March 23rd. You can find the video and audio of this talk on my website at http://www.andyfitzgeraldconsulting.com/speaking/prototyping-ia
There's an entire industry sprouting up around Social Media. Here's what you need to know.
Presentation for Southern New Hampshire University Students.
Jorrit Ebben himsseu Dementia 20180529Jorrit Ebben
In the session I presented an overview of innovations in health technology used in the Netherlands and by Siza and Academy het Dorp for people with brain injury and/or learning disabilities to show the cross-overs with dementia.
SMSS 2018 - Using an Instagram Story to Help Sexual Assault SurvivorsJon McBride
BYU found some important pieces of data in its campus climate survey: 1. Survivors of sexual assault first turn to friends and roommates. 2. Friends and roommates felt ill equipped to help. 3. Friends and roommates wanted to help. So we created an Instagram story directed to the entire student body, coaching them on what to say, how to help and what specific resources to point their friends and roommates to, if they come to them for support after an assault.
My talk from the 2018 Information Architecture Summit in Chicago on March 23rd. You can find the video and audio of this talk on my website at http://www.andyfitzgeraldconsulting.com/speaking/prototyping-ia
There's an entire industry sprouting up around Social Media. Here's what you need to know.
Presentation for Southern New Hampshire University Students.
Jorrit Ebben himsseu Dementia 20180529Jorrit Ebben
In the session I presented an overview of innovations in health technology used in the Netherlands and by Siza and Academy het Dorp for people with brain injury and/or learning disabilities to show the cross-overs with dementia.
SMSS 2018 - Using an Instagram Story to Help Sexual Assault SurvivorsJon McBride
BYU found some important pieces of data in its campus climate survey: 1. Survivors of sexual assault first turn to friends and roommates. 2. Friends and roommates felt ill equipped to help. 3. Friends and roommates wanted to help. So we created an Instagram story directed to the entire student body, coaching them on what to say, how to help and what specific resources to point their friends and roommates to, if they come to them for support after an assault.
Determine the frequency of 16 high-risk conditions and associated complications in a Michigan state-wide network of academic and community EDs (MiPEM) during the COVID-19 pandemic
Acute ischemic stroke (AIS) management is time-sensitive
Co-management between Emergency Medicine and Neurology
In-person neurology-based stroke team
EM resident and attending
Goal to develop a workflow where EM residents became active decision-makers in care of AIS patients
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
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Determine the frequency of 16 high-risk conditions and associated complications in a Michigan state-wide network of academic and community EDs (MiPEM) during the COVID-19 pandemic
Acute ischemic stroke (AIS) management is time-sensitive
Co-management between Emergency Medicine and Neurology
In-person neurology-based stroke team
EM resident and attending
Goal to develop a workflow where EM residents became active decision-makers in care of AIS patients
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Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
ABDOMINAL TRAUMA in pediatrics part one.drhasanrajab
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Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
32. Cindy H. Hsu, MD, PhD
Assistant Professor
Department of Emergency
Medicine & Surgery
March 2nd, 2018
Automated
extracranial
internal carotid
artery ultrasound
sensor for TBI
NIK THEYYUNNI @HEYDRNIK #BRF18
37. PUT ME OUT OF A JOB
NIK THEYYUNNI @HEYDRNIK #BRF18
Editor's Notes
Rather than presenting one specific research project today I want to give you an overview – a more global sense - of some of the things we’re doing, and what I think our research program builds towards. And I want to talk a little bit about research we do that’s really unique to our program.
I want you to keep in the back of your mind as I go our overarching goal with out research
Which is to put ourselves out of a job.
My goal is, by the time I retire, they won’t need to replace me. We don’t have airway directors, some day we might not need US directors. So how do we do that? US is a complex skill, we spend a lot of resources right now to teach our residents how to scan. How do we get from here to no need for me? Well lets talk research
This one is chocolate. And this is a big part of how we make me obsolete. If EVERYONE knows ultrasound, why have an US director? It needs to be in the water
This one is chocolate. And this is a big part of how we make me obsolete. If EVERYONE knows ultrasound, why have an US director?
This one is chocolate. And this is a big part of how we make me obsolete. If EVERYONE knows ultrasound, why have an US director?
Motivating people to learn. Some of you have participated or seen some of the game based US teaching we do, and we work on research with that as well, this year I was involved in a manuscript talking about Sonoslam We do some of this – lets teach EVERYONE todo ultrasound
We do a lot of educational work.
Strain of our research is figuring out how to get everyone educated.
Some of that is defining what they need to be taught would be familiar to the med ed/MERG people and done in collaboration with them – The Delphi method
Sonogames
We’ve worked with national colleagues to set up an educational endevour called sonoslam focused on gamifiying ultrasound education for students. Showcase novel educational methods
Gameification
We use phantoms and more advanced simulators or normal live models to both educate and assess students knowledge. This picture is one of the teams using an advanced model that simulates transvaginal ultrasound – a procedure that’spretty rare for students to get access to, gamification spurs our competitive edges
I think if
This one is chocolate. And this is a big part of how we make me obsolete. If EVERYONE knows ultrasound, why have an US director?
People still need to do the scans, how can we reduce the barriers to do each of these things? Automate automate, automate. We don’t count our own cells anymore, how much of our own ultrasound will we do in 10 years
We do this elsewhere! Noone uses a microscope anymore! Maybe some ultrasound applications can be fully or partially automated. If EVERYONE does ultrasound, and we can automate some of the harder/tedious/technical parts, maybe that takes us the rest of the way. What I’m about to show you is where I think U of M has a unique chance to make out mark
We do this elsewhere! Noone uses a microscope anymore! Maybe some ultrasound applications can be fully or partially automated. If EVERYONE does ultrasound, and we can automate some of the harder/tedious/technical parts, maybe that takes us the rest of the way. What I’m about to show you is where I think U of M has a unique chance to make out mark
So pick an area where acquisition could conceivably be much easier to start with.
The Neck has great windows and lots of stuff to look at
We do this elsewhere! Noone uses a microscope anymore! Maybe some ultrasound applications can be fully or partially automated. If EVERYONE does ultrasound, and we can automate some of the harder/tedious/technical parts, maybe that takes us the rest of the way. What I’m about to show you is where I think U of M has a unique chance to make out mark
So pick an area where acquisition could conceivably be much easier to start with.
The Neck has great windows and lots of stuff to look at
Manuscript submitted for publication
We do this elsewhere! Noone uses a microscope anymore! Maybe some ultrasound applications can be fully or partially automated. If EVERYONE does ultrasound, and we can automate some of the harder/tedious/technical parts, maybe that takes us the rest of the way. What I’m about to show you is where I think U of M has a unique chance to make out mark
Further and further beyond the basics.
We do this elsewhere! Noone uses a microscope anymore! Maybe some ultrasound applications can be fully or partially automated. If EVERYONE does ultrasound, and we can automate some of the harder/tedious/technical parts, maybe that takes us the rest of the way. What I’m about to show you is where I think U of M has a unique chance to make out mark
So pick an area where acquisition could conceivably be much easier to start with.
The Neck has great windows and lots of stuff to look at
This is our platform, can use it for different things
Target Product Profile
Description of product that will eventually be sold
Anticipated Feature/Benefits - (Performance level required for clinical and commercial success)
1) Clearly articulate the clinical workflow process.
2) Describe your Envisioned Product. A wireless ultrasound-based disposable smart sensor patch that nurses can quickly and easily place on the side of a patient’s neck with little training to provide continuous volume responsiveness trending.
How do you expect this to get commercialized after Coulter funding?
Initially form a company and raise angel capital as well as SBIR/STTR funding
Ultimately exit through sale of company
- Form a new company and raise venture capital/angel $, or
- Direct license to a revenue generating company
Speak to Jack Miner – venture center
Early success with this platform, for our TBI research project ct here is the sensor quantifying blood flow in a phantom model. I can’t get into the secret sauce thaty makes this work, but it’s not using doppler, and it’s a promising new way for us to get at this problem.
This is our platform, can use it for different things