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NanoSafety – A Safe-by-Design Manufacturing Process
Dr Selina Ambrose
11th July 2019
Technical talk about Promethean’s technology and capabilities already presented by Ed Lester,
our Technical Director
Promethean design, develop and manufacture inorganic nanomaterial dispersions
Use Continuous-flow hydrothermal and solvothermal synthesis
Promethean Particles
Infinity Series - 1,000+ tons/yr
The world’s largest continuous multi-nanomaterial manufacturing plant
• Manufacture nanoparticles in liquid dispersion, not dry powders
• Work with our customers to adapt the downstream processing so that nanomaterials are not
handled in dry powder form
• Greatly reduced inhalation risks; easier to contain nanomaterials
• One approach is to reduce risk by reducing exposure
• Also consider ways to reduce hazard through collaborative projects…
A Safe-by-Design Manufacturing Approach
Risk = Hazard x Exposure
• Hand-in-hand with our innovation
• Strong involvement in collaborative European Projects focussing on Nano Safety:
• NanoMILE (FP7): Engineered nanomaterial mechanisms of interactions with living systems
and the environment
• NanoFASE (H2020): Nanomaterial Fate and Speciation in the Environment
• Involved in other European projects which have Tasks specifically addressing Nano Safety:
• Cell3Ditor (H2020): development of a 3D printing technology to produce Solid Oxide Fuel Cell
(SOFC) stacks
• CARMOF (H2020): tailor made 3D printed structures based on CNTs and MOFs for efficient
CO2 capture
Nano Safety is Promethean’s Priority
Article published 29th May 2019 in
The Guardian
Nano Safety in the Media
• Data obtained from animal studies
• Different animals respond differently from each other and from
humans
• Should consider Occupational Health data from
workers/manufacturers?
GBP Consulting Ltd
1. Nanomaterials are not the next asbestos
2. Particle toxicity appears primarily predictable based on composition and,
for inhalation, persistence and shape
3. To date a uniquely “nano” mechanism for toxicity has not been
established
4. Natural and incidental nanomaterials predominate from an exposure
perspective
5. If regulation is to be applied, base on material function rather than size
https://ceint.duke.edu/news-events/conference/nano2018
13TH INTERNATIONAL CONFERENCE ON THE ENVIRONMENTAL
EFFECTS OF NANOPARTICLES AND NANOMATERIALS (ICEENN 2018)
SCIENTIFIC HIGHLIGHTS - CONCLUSIONS
Thank you for listening!
Promethean Particles are exhibiting at Stand 1024
Contact:
Dr Selina Ambrose, Technical Manager
selina.ambrose@proparticles.co.uk
+44 (0) 115 9678119
www.prometheanparticles.co.uk
@ProParticles

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Selina ambrose promethean particles

  • 1. NanoSafety – A Safe-by-Design Manufacturing Process Dr Selina Ambrose 11th July 2019
  • 2. Technical talk about Promethean’s technology and capabilities already presented by Ed Lester, our Technical Director Promethean design, develop and manufacture inorganic nanomaterial dispersions Use Continuous-flow hydrothermal and solvothermal synthesis Promethean Particles
  • 3. Infinity Series - 1,000+ tons/yr The world’s largest continuous multi-nanomaterial manufacturing plant
  • 4. • Manufacture nanoparticles in liquid dispersion, not dry powders • Work with our customers to adapt the downstream processing so that nanomaterials are not handled in dry powder form • Greatly reduced inhalation risks; easier to contain nanomaterials • One approach is to reduce risk by reducing exposure • Also consider ways to reduce hazard through collaborative projects… A Safe-by-Design Manufacturing Approach Risk = Hazard x Exposure
  • 5. • Hand-in-hand with our innovation • Strong involvement in collaborative European Projects focussing on Nano Safety: • NanoMILE (FP7): Engineered nanomaterial mechanisms of interactions with living systems and the environment • NanoFASE (H2020): Nanomaterial Fate and Speciation in the Environment • Involved in other European projects which have Tasks specifically addressing Nano Safety: • Cell3Ditor (H2020): development of a 3D printing technology to produce Solid Oxide Fuel Cell (SOFC) stacks • CARMOF (H2020): tailor made 3D printed structures based on CNTs and MOFs for efficient CO2 capture Nano Safety is Promethean’s Priority
  • 6. Article published 29th May 2019 in The Guardian Nano Safety in the Media • Data obtained from animal studies • Different animals respond differently from each other and from humans • Should consider Occupational Health data from workers/manufacturers?
  • 7. GBP Consulting Ltd 1. Nanomaterials are not the next asbestos 2. Particle toxicity appears primarily predictable based on composition and, for inhalation, persistence and shape 3. To date a uniquely “nano” mechanism for toxicity has not been established 4. Natural and incidental nanomaterials predominate from an exposure perspective 5. If regulation is to be applied, base on material function rather than size https://ceint.duke.edu/news-events/conference/nano2018 13TH INTERNATIONAL CONFERENCE ON THE ENVIRONMENTAL EFFECTS OF NANOPARTICLES AND NANOMATERIALS (ICEENN 2018) SCIENTIFIC HIGHLIGHTS - CONCLUSIONS
  • 8. Thank you for listening! Promethean Particles are exhibiting at Stand 1024 Contact: Dr Selina Ambrose, Technical Manager selina.ambrose@proparticles.co.uk +44 (0) 115 9678119 www.prometheanparticles.co.uk @ProParticles