iron & b12 deficiency anemia

1. iron deficency anemiya

2. Iron Deficiency Anemia
• "anemia" usually refers to a condition in
which our blood has a lower than normal
number of red blood cells.
• Iron is an essential mineral that is needed
to form hemoglobin, an oxygen carrying
protein inside red blood cells.
• Iron deficiency anemia is a condition in
which the body lack enough red blood cell
to transport oxygen-rich blood to body
tissues

4. Etiology
• Iron-deficiency anemia is usually due
to :
 blood loss
 poor diet
 an inability to absorb enough iron
from food.

5. • Blood Loss
 Blood lost causes iron depletion
In women, long or heavy menstrual
periods or bleeding fibroids in the
uterus.
Childbirth
Internal bleeding
• Poor Diet
Low iron intake.
During some stages of life, such as
pregnancy and childhood.

6. • Iron-deficiency anemia can cause:
brittle nails
cracks in the sides of the mouth
symptoms

7.  Extreme fatigue (tiredness)
chest pain
tachycardia

8. an enlarged spleen
Cold hands and feet
frequent infections.
Irritability
shortness of breath
swelling or soreness of the tongue

9. • Some signs and symptoms of iron-deficiency
anemia are related to the condition's causes.
 A sign of intestinal bleeding is bright red
blood in the stools or black, tarry-looking
stools.
 Very heavy menstrual bleeding, long periods,
or other vaginal bleeding may suggest that a
woman is at risk for iron-deficiency anemia.

10. • Auscultation:-
functional systolic murmur at the
apex of the heart
• Laboratary investigation:-
reduced in the level of
hemoglobin with combination of reduced
amount of eretrocytes

11. TREATMENT
IRON SUPPLEMENT

12. ORAL IRON THERAPY
• Oral iron treatment may require 3-6
months to replenish body stores.

13. B12 DEFICENCY ANEMIA
• This anemia associated with violation of
the synthesis of DNA and RNA
cheracterised by the type of megaloblastic
hematopoiesis,intramedullary destruction
of red blood cells,pancytopenia with
hyperchromic anemia.

14. ETIOLOGY
• Violation of the secretion and absorbtion
of vitamin B12 (atropy of gastric mucosa)
• Competitive consumption of vit B12 (broad
tapeworm infection and other worm
infections)

15. Symptoms:-
• Specific features of anemic syndrome
• Pained tongue that is atropy of tongue
• Burning sensation and pain in the tongue
• Pain in legs,stagging during
walking,sensitivity distrabence,muscle
atropy
• Signs of myelosis

16. Lab diagnosis:-
• Increase in CPU(hyper chromia)
• Macrocytosis,megalocytosis.
• Polysegmentary nuclei of nutrophils in the
blood
• Myelogram:-large quantities of
megaloblasts determined

17. treatment:-
• Vit B12 1mcg 500 once a day by im
injection 4-6weeks and then 200 mg 1
time per week for 2 months
• Treatment of the underlying disease
• Diet(receive a sufficient quantity of
meat,vegetabuls and fruits)

18. REFERENCES
• The HealthCentralNetwork, Inc.Copyright © 2001-2011. Treatment of Iron
Deficiency,retrieved on 2011-10-05. Retrieved from
http://www.healthscout.com/ency/68/575/main.html#TreatmentofIronDeficie
ncy
• A-Z Drug Facts for the Professional,Copyright © 2000-2011. Iron
supplement, retrieved on 2011-10-03. Retrieved from
ttp://www.drugs.com/ppa/
• A-Z Drug Facts for the Professional,Copyright © 2000-2011. What should I
avoid while taking iron supplement, retrieved on 2011-10-03. Retrieved from
http://www.drugs.com/ferrous_sulfate.html
• National Center for Biotechnology Information, U.S. National Library of
Medicine 8600 Rockville Pike, Bethesda MD, 20894 USA Iron supplements:
a common cause of drug interactions, retrieved on 2011-10-06. Retrieved
from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1368348/
• Basic and clinical pharmacology 10th
edition, Beram.G. Katzung,MD,PhD.
Professor Emertus, Department of cellular & Molecular Pharmacology,
University of California San Francisco.