4. INTRODUCTION
VITAMIN
• vitamin are a class of organic
compounds categorised as essential
nutrients.
• They are required by the body in very
small amounts.
• They fall in the category of micro
nutrients.
5. Vitamin are divided into 2 groups:-
vVITAMIN
VITAMIN A,D ,E &
K
VITAMIN B &
VITAMIN C
6.
7. FAT SOLUBLE VIT-
The fat soluble vitamin A,D,E & K. Control
protein synthesis at either the
trancriptional or post transcriptional level.
Breast feeding is deficient in both vitamin
D & K and must be supplement with
these vitamins to protect breast feed
infants.
8.
9. VITAMIN- ‘A’
Vitamin-A is a fat soluble
vitamin.Vitamin-A activity is also
possessed by carotenoids found in plants.
Hence, carotenoids are caused Pro
Vitamin-A.
10. It occurs in 4 forms:-
Vit.A
(retinol)
Vit.A
(found in liver of
fresh water fish)
Vit.A acid
(retinoic acid)
Vit.A aldehyde
(retinol retinence)
11. ABSORPTION-
Vitamin-A is absorbed through
lymphatic system into blood stream
along with fat & stored in large amount
in liver.
12.
13. FUNCTIONS OF VIT-A-
Production of retinal pigments.
Its maintaing the integrity & the normal
functioning of glandular & epithelial
tissue.
It supports the growth especially
skeletal muscles growth.
It is an anti infective.
14. BENEFITS
It is important for normal vision,and for the
immune system.
Vitamin A also helps the heart, lungs,
kidney and others organs work properly.
27. PREVENTION
Maternal high supplementation.
Increased consumption of vit.A.
Diet which rich in vitamin A.
Adminstration of vit.A as a part of the
immunization schedule.
29. HYPERVITAMINOSIS ‘A’ -
An excess intake of retinal causes
nausea,anorexia,& sleep disorders
followed by desquatmation.
30.
31. VITAMIN ‘D’
Vitamin D is referred to as-
‘SUNSHINE VITAMIN’.
Because it can be synthesised in body in
presence of the UV rays from sun.
Vitamin D is essential for bone growth or health
and regulation of calcium & phosphorus
levels.
34. FUNCTIONS OF VIT.D-
It promote absorption of calcium &
phosphorus.
Reabsorption & mobilization.
It causes mineralization of the bones.
It has immune regulatory role.
37. DAILY REQUIREMENTS
Infants, children, pregnant &
nursing women need 400I.U of
vitamin D.
Older children & adults require 200
I.U of vitamin D.
38. VITAMIN D DEFICIENCY-
Lack of vitamin D result in vitamin D
deficiency in children.
Deficiency of vitamin D leads to a
disease called RICKETS.
39.
40. RICKETS
Rickets occurs in a result of dietary
deficiency of vitamin D.
In rickets, the failure of mineralisation of
growing bones or osteoid tissue occurs.
Thus bones becomes weak & an adapts an
abnormal shape & under stress.
41.
42. PATHOPHYSIOLOGY-
Vitamin D is useful for absorption of calcium from gut
Sunlight especially UV rays let human cells to convert vit.D from
in active stage
Inabsence of vitamin D
Dietary calcium is not properly absorbed
Resulting in hypocalcemia leads to skeletal deformities & neuro
muscular symptoms.
43.
44. SIGN & SYMPTOMS-
Common skeletal deformities
Delayed closure of anterior fontaneles
Enamel defect
Enlargement of long bones around wrist &
ankel
Bow legs
Osteomalacia
45.
46. COMPLICATIONS
Permanent skeletal deformity
Poor motor skills
Delay in physical growth
Severe vitamin D deficiency can lead to
seizures.
50. MANAGEMENT
For the treatment of the RICKETS &
OSTEOMALACIA, vitamin D is given
in a dose of 1000-5000IU, orally for a
month, followed by 800 IU daily for 6
months.
53. HYPERVITAMINOSIS ‘D’-
Excess of vitamin D intake of leads to
hypervitaminosis D.
It is manifested by-
• Dehydration
• Vomiting
• Decreased appetite
• Irritability
• Fatigue
• Muscle weakness
54.
55. VITAMIN ‘E’-
Vitamin E is a group of 8 closely related fat
soluble compounds 4 Tocopherols & 4
Tocotrinols.
There are three components of vitamin E
viz. alpha, beta, gamma tocopherol.
56. ABSORPTION
Vitamin E is absorbed with fat in
intestines. It is stored in liver
muscles & body fat.
57.
58. FUNCTION OF VITAMIN E
It has an anti oxidant activity
It prevent pre oxidation of poly
unsaturated fatty acids in tissues and cell
membranes.
It protects RBCs from hemolysis due to
oxidazing agents.
It has antisterility action.
69. VITAMIN K DEFICIENCY-
Vitamin K deficiency occurs when the
child does not get enough vitamin K.
It interference with child’s normal
physiological changes.
70.
71. SIGN & SYMPTOMS-
Abnormal bleeding even small test.
Spontaneous nose bleeding.
Bruise.
Bleeding gums.
Blood in urine or stool.
72.
73. MANAGEMENT
Dietary intake of vitamin K rich food
items.
Adminstration of oral suspension of
vitamin K.
Injection vitamin K can be given
intramusculary.
74. HYPERVITAMINOSIS ‘K’
V itamin K toxicity is extremely rare.
When toxicity is occur, it manifested with signs of
jaundice, hyperbilirubinemia, hemolytic anemia &
kernicterus in infants.
It may result in –
• Nausea
• Diarrhoea
• Hemorrhage
• Heart palpitation
75.
76. SUMMARIZE THE TOPIC-
Definition of VITAMIN- A,D,E & K.
Absorption of VITAMIN- A,D,E & K.
Functions of VITAMIN- A,D,E & K.
Sources of VITAMIN- A,D,E & K.
Deficiency of VITAMIN- A,D,E & K.
Causes of VITAMIN- A,D,E & K.
Sign & symptoms of VITAMIN- A,D,E & K.
Pathophysiology of VITAMIN- D.
Management of VITAMIN- A,D,E & K.
Prevention of VITAMIN- A,D,E & k.
77.
78. RECAPTUALIZE THE TOPIC-
Define the VITAMIN A,D,E & K ?
What are the sources of VITAMIN A,D,E & K?
What are the functions of the VITAMIN A, D,E & K ?
Define the VITAMIN A,D,E & K deficiency?
What are the causes of VITAMIN A,D,E & K deficiency?
Which symptoms are appear in the VIT. A,D,E & K deficiency?
What is the pathophysiology of VIT.D deficiency?
How will manage the VIT.A,D,E & K deficiency?
How will prevent the VIT. A,D,E & K deficiency?