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INTERESTING CASE
PRESENTATION
Presented by : Dr Shaz Pamangadan
Chair : Prof . Sudeep .K
• 40/F
• Housewife
• presenting complaints :
Headache - 3 days
Difficulty in closing right eye – 3 days
• Her headache started insidiously, had a
progressive course, squeezing nature , mainly
bifrontal distribution and was associated with
nausea, vomiting, dizziness, transient visual
disturbances in her right eye, and a feeling of
both her ears being clogged.
• A day prior to the presentation, she started to
feel numbness and weakness of the right side of
her face, along with an inability to close her right
eye properly.
• No h/o diplopia, loss of vision, photophobia,
tinnitus, or any feeling of weakness,
numbness, or tingling in other locations of her
body.
• She had no history of migraine headaches, tick
bite, or any recent illness or fever, trauma .
• She was not taking oral contraceptive pills at
the time.
Past History
• History of Obesity, BMI  of 32
• Systemic Hypertension  10 years
• No h/o T2dm , dyslipidemia or significant
medical or surgical history in the past .
Family history
• No significant illnesses in family
Personal history
• Mixed diet.
• Normal bowel bladder.
• No addictions.
• Sleep and appetite adequate.
To summarize …
On examination
• Conscious , oriented , co-operative .
• BP – 140/90 mmHg
• PR – 88/mt regular .
• T – Afebrile
• RR – 18/mt
• GRBS- 97mg/dl.
General examination
• No pallor ,icterus , cyanosis , clubbing , lymph
node enlargement , oedema .
• Skin , hair , nails appear normal .
• No thyroid swelling
CNS Examination
• HMF  fully alert and oriented, fluent speech
and intact comprehensive abilities.
• CN  3–4 mm pupils, PEARL & Accommodation;
intact extra-ocular movements, no nystagmus,
saccadic movement or skew, full visual fields.
• No signs of abducent nerve palsy were present.
• There was facial asymmetry evident by right
lower facial droop, weaker right eye closure, and
limited ability to raise the right eyebrow.
• Facial sensation  equal on both sides, with a
strong jaw opening and a midline tongue of
good power. shoulder shrug was symmetrical,
and hearing was intact.
• A fundus examination revealed bilateral grade
I–II papilledema.
• No signs of meningeal irritation.
• motor function, sensation, gait analysis, skull
and spine -wnl
Other systems
• CVS – S1S2 heard . No murmur
• RS – NVBS b/l . No added sounds
• P/A – soft ; No HSM
investigations
• Blood r/e ,
• lft ,
• rft ,
• se ,rbs
• ur/e ,
• cxr-pa view ,
• ecg ,
• s.ca , s.mg , s.ph , s.uric acid  normal
Eventually ???
• She underwent a computed tomography (CT)
scan of her head that showed right-sided
pontomedullary hypodensity.
• Brain magnetic resonance imaging (MRI) with
magnetic resonance venography (MRV)
revealed a stenosis in the lateral aspect of the
transverse sinus, a partially empty sella
turcica, and a picture of mild papilledema.
Lumbar puncture :
• opening pressure  28 cm of csf
• The cytological and chemical findings of the LP
WBCs  2
• lymphocytes 100%
• protein 24
• RBCs 13
• Glucose 58
• c/s ,gram stain, ada , normal
Differential diagnosis
• Migraine variants.
• Meningitis/meningoencephalitis.
• Subarachnoid hemorrhage.
• Intracranial hemorrhage .
• Hydrocephalus.
• Intracranial epidural abscess.
• Lymes disease.
• Pseudotumour cerebri.
Diagnosis ???
• Pseudotumour cerebri
Or
• Benign intracranial hypertension
Or
• Idipathic intracranial hypertension.
• She was started on prednisone 60 mg daily
for 5 days and 500 mg of acetazolamide twice
daily.
• Two days later, she reported a dramatic
improvement in both the headache and the
facial nerve palsy. A week later, right facial
nerve examination was done, which was
completely normal.
In our patient …?
• Why seventh nerve palsy ??? Not sixth ???
Thank you .
Idiopathic intracranial hypertension - Dr Shaz Pamangadan
Idiopathic intracranial hypertension - Dr Shaz Pamangadan
Idiopathic intracranial hypertension - Dr Shaz Pamangadan
Idiopathic intracranial hypertension - Dr Shaz Pamangadan

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Idiopathic intracranial hypertension - Dr Shaz Pamangadan

  • 1. INTERESTING CASE PRESENTATION Presented by : Dr Shaz Pamangadan Chair : Prof . Sudeep .K
  • 2. • 40/F • Housewife • presenting complaints : Headache - 3 days Difficulty in closing right eye – 3 days
  • 3. • Her headache started insidiously, had a progressive course, squeezing nature , mainly bifrontal distribution and was associated with nausea, vomiting, dizziness, transient visual disturbances in her right eye, and a feeling of both her ears being clogged. • A day prior to the presentation, she started to feel numbness and weakness of the right side of her face, along with an inability to close her right eye properly.
  • 4. • No h/o diplopia, loss of vision, photophobia, tinnitus, or any feeling of weakness, numbness, or tingling in other locations of her body. • She had no history of migraine headaches, tick bite, or any recent illness or fever, trauma . • She was not taking oral contraceptive pills at the time.
  • 5. Past History • History of Obesity, BMI  of 32 • Systemic Hypertension  10 years • No h/o T2dm , dyslipidemia or significant medical or surgical history in the past .
  • 6. Family history • No significant illnesses in family
  • 7. Personal history • Mixed diet. • Normal bowel bladder. • No addictions. • Sleep and appetite adequate.
  • 9. On examination • Conscious , oriented , co-operative . • BP – 140/90 mmHg • PR – 88/mt regular . • T – Afebrile • RR – 18/mt • GRBS- 97mg/dl.
  • 10. General examination • No pallor ,icterus , cyanosis , clubbing , lymph node enlargement , oedema . • Skin , hair , nails appear normal . • No thyroid swelling
  • 11. CNS Examination • HMF  fully alert and oriented, fluent speech and intact comprehensive abilities. • CN  3–4 mm pupils, PEARL & Accommodation; intact extra-ocular movements, no nystagmus, saccadic movement or skew, full visual fields. • No signs of abducent nerve palsy were present. • There was facial asymmetry evident by right lower facial droop, weaker right eye closure, and limited ability to raise the right eyebrow.
  • 12. • Facial sensation  equal on both sides, with a strong jaw opening and a midline tongue of good power. shoulder shrug was symmetrical, and hearing was intact. • A fundus examination revealed bilateral grade I–II papilledema. • No signs of meningeal irritation. • motor function, sensation, gait analysis, skull and spine -wnl
  • 13. Other systems • CVS – S1S2 heard . No murmur • RS – NVBS b/l . No added sounds • P/A – soft ; No HSM
  • 14. investigations • Blood r/e , • lft , • rft , • se ,rbs • ur/e , • cxr-pa view , • ecg , • s.ca , s.mg , s.ph , s.uric acid  normal
  • 15. Eventually ??? • She underwent a computed tomography (CT) scan of her head that showed right-sided pontomedullary hypodensity. • Brain magnetic resonance imaging (MRI) with magnetic resonance venography (MRV) revealed a stenosis in the lateral aspect of the transverse sinus, a partially empty sella turcica, and a picture of mild papilledema.
  • 16. Lumbar puncture : • opening pressure  28 cm of csf • The cytological and chemical findings of the LP WBCs  2 • lymphocytes 100% • protein 24 • RBCs 13 • Glucose 58 • c/s ,gram stain, ada , normal
  • 17. Differential diagnosis • Migraine variants. • Meningitis/meningoencephalitis. • Subarachnoid hemorrhage. • Intracranial hemorrhage . • Hydrocephalus. • Intracranial epidural abscess. • Lymes disease. • Pseudotumour cerebri.
  • 18. Diagnosis ??? • Pseudotumour cerebri Or • Benign intracranial hypertension Or • Idipathic intracranial hypertension.
  • 19. • She was started on prednisone 60 mg daily for 5 days and 500 mg of acetazolamide twice daily. • Two days later, she reported a dramatic improvement in both the headache and the facial nerve palsy. A week later, right facial nerve examination was done, which was completely normal.
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  • 36. In our patient …? • Why seventh nerve palsy ??? Not sixth ???
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