A review of Dietary Anticancer Agents Available abundantly in nature...

1. DIETARY ANTICANCER AGENTS
University College of Technology,O.U
Submitted By
Sana Yasmeen
H.No.1008-17-884-015

2. CONTENTS
Introduction
Dietary Anticancer Agents
i. Curcuma
ii. Green Tea
iii. Ginger
iv. Fenugreek
v. Paprika and Chilli
vi. Flaxseed oil
vii. Soybean
viii. Berries
ix. Citrus Fruits
x. Cruciferous vegetables
xi. Clove
xii. Cumin
xiii. Fennel
xiv. Garcinia
xv. Camphor
xvi. Mustard
Conclusion
References

3. CANCER
What is Cancer?
We have varied definitions for cancer ….
By summarizing all of them.We get to know that,
Cancer is the condition developed out of long term
exposure to an agent(physical,chemical,biological).

4. cancer is “TREATABLE”
is “ERADICABLE”
 As I’ve grown up I’ve observed….....the Popularity of
a condition termed “cancer”……Now it seemed to be
turned as a regular emotion amongst the World
population,whose consequences are prefixed.
My Contribution to the World as a Science Aspirer is
To eliminate the fact that cancer isn’t
treatable……..Infact make them aware of the
supplements gifted by the nature which if included in
our diet reduces the risk of cancer…..to cent percent.

5. Dietary Anticancer Agents
These are the agents which forms major portion of
our daily diet.Their generalized mechanistic action
is:
They are
Antioxidant,
Free-radical scavenger,
Inhibitors of (lipoxygenase,urokinase
enzymes)….etc…

6. CURCUMA
The active constituent in curcuma is “CURCUMIN”.
Curcumin is responsible for antitumorigenic effect

7. Green Tea
The catechin (-)-Epigallocatechin-3-gallate(EGCG) is
responsible for inhibition of extensive cell
proliferation.

8. GINGER
The pungent constituents(gingerol,zingerone
and paradol) exhibits cancer preventive activity.

9. FENUGREEK
The anticarcinogenoic activity of fenugreek has
been reported by several workers. Devasena and
Menon (2003) observed that fenugreek seeds in
the diet inhibited colon carcinogensis, by
modulating the activities of b-glucoronidase and
mucinase.

10. PAPRIKA AND CHILLI
Zhang et al. (2003) found the potential of capsaicin
in inhibiting the growth of adult T-cell leukaemia
cells. The inhibitory effect was due mainly to the
induction of cell cycle arrest and apoptosis.

11. FLAXSEED OIL
Flax lignans, have shown promising affect towards
hormone-dependant cancerous condition.
Flaxseed along with Sesame seed produces
mammalian lignans, which produces potential
anticancer effects

12. SOYBEAN
The soy isoflavone(flavonoid),Lunasin(peptide),soy
saponins have demonstrared anticancerous
activity.

13. BERRIES
Anthocyanins ,have shown inhibition of
carcinogenesis, and suppression of progression
and proliferation of tumor .

14. CITRUS FRUITS
Hesperidin(flavonoid),Limnoid(terpenoid)have
found to show profound action against the cancer
cell mediated pathways.

15. CRUCIFEROUS VEGETABLES
Cruciferous vegetables have decreased the risk of
breast cancer by 40% because of high fibre content.

16. CLOVE
Clove has strong anticancerous properties.The
sesquiterpenes, b-cayophyllene,b-cayophyllene
epoxide, a-humulene, ahumuleneepoxide and
eugenol present inclove oil showed potent
anticarcinogenicactivity by inducing the detoxifying
enzyme,glutathione-S-transferase, in mouse
liverand small intestine (Zheng et al., 1992).

17. CUMIN
Cumin seeds may also have anticarcinogenic
properties, as they protect from developing stomach
or liver tumours.
This effect may stem from cumin’s free radical
scavenging abilities and its ability to enhance the
liver’s detoxification enzymes.(Gurudeep et.al 2003)

18. FENNEL
Anetholes from fennel, have the potential to be
used to prevent and treat cancer (Aggarwal and
Shishodia, 2006).

19. GARCINIA
Human telomerase reverse transcriptase gene
expression was inhibited by gambogic acid in human
hepatoma SMMC-7721 cells, indicating the
gambogic acid’s potent anticancer activity (Guo et
al., 2006).

20. CAMPHOR
The use of camphor odor as a conditioning agent
for the cancer cells of YC8 lymphoma in mice gave
a suppressive effect on the growth of YC8 tumor,
when it is combined with immunotherapy
treatment.
Camphor prior to a radiation showed reduced
growth of tumor volume.

21. MUSTARD
Mustard seeds, Brassica juncea, are also an
excellent source of selenium, a trace element that
is also thought to have an anti-cancer effect.

22. CONCLUSION
To establish Cancer Eradication Committee from
Primary to International level.
To regularise the consumption of the above
mentioned,as mandate from Housing to
Schooling,and have a Happy,Healthy,Cancer-free
society.

23. REFERNCES
1. www.slideshare.net
2. Chemistry of Spices…..(book from IISR)
3. www.Bing.com
4. www.wikipedia.org
5. http://pubchem.ncbi.nlm.nih.gov/

24. REFERENCES