A blood product is any therapeutic substance prepared from human blood. This includes whole blood; blood components; and plasma derivatives. Whole blood is not commonly used in transfusion medicine.

1. BLOOD PRODUCT
Presented by:Yadav Suman

2. Whole blood and blood components
Withdrawn from human who are certified by a physical as being free of
transmissible disease and mixed with a suitable anticoagulant.
Whole human blood is the final mixture of blood and anticoagulant solution
contains not less then 9.7% w/v of hemoglobin.
Whole blood is a mixture of plasma and blood cells.
The blood plasma is made up of water ( 92%), plasma proteins, inorganic salts,
nutrients, waste materials, hormones, and gases, albumins are the most abundant
plasma protein.
The main function of albumin is to maintain normal plasma osmotic pressure and
it act as carrier molecules for free fatty acids, some drugs and hormone.

4. PLASMA SUBSTITUTES
 Any liquid used to replace blood plasma, usually a saline
solution, often with serum albumins, dextrans or other
preparations.
 These substances do not enhance the oxygen- carrying capacity
of blood, but merely replace the volume.
 They are also used to treat dehydration.

7. Factor affecting donor
• Age:
• You are aged between 18 and 65.
• In some countries national legislation permits 16–17 year-olds to donate
provided that they fulfil the physical and hematological criteria required and
that appropriate consent is obtained.
• In some countries, regular donors over the age of 65 may be accepted at
the discretion of the responsible physician. The upper age limit in some
countries are 60.

8. • Weight:
• You weigh at least 50 kg.
• In some countries, donors of whole blood donations should weigh at least 45 kg to donate 350 ml ±
10% .
• Health:
• You must be in good health at the time you donate.
• You cannot donate if you have a cold, flu, sore throat, cold sore, stomach bug or any other infection.
• If you have recently had a tattoo or body piercing you cannot donate for 6 months from the date of the
procedure. If the body piercing was performed by a registered health professional and any
inflammation has settled completely, you can donate blood after 12 hours.
• If you have visited the dentist for a minor procedure you must wait 24 hours before donating; for major
work wait a month.
• You must not donate blood If you do not meet the minimum hemoglobin level for blood donation
• * A test will be administered at the donation site. In many countries, a hemoglobin level of not less
than 12.0 g/dl for females and not less than 13.0 g/dl for males as the threshold.

9. • Travel:
Travel to areas where mosquito-borne infections are endemic, e.g. malaria, dengue and Zika virus
infections, may result in a temporary deferral .
• Many countries also implemented the policy to defer blood donors with a history of travel or residence for
defined cumulative exposure periods in specified countries or areas, as a measure to reduce the risk of
transmitting variant Creutzfeldt-Jakob Disease (vCJD) by blood transfusion.
• Behaviors:
• You must not give blood:
• Individuals with behaviors below will be deferred permanently:
• Have ever had a positive test for HIV (AIDS virus)
• Have ever injected recreational drugs.
• In the national blood donor selection guidelines, there are more behavior eligibility criteria. Criteria could be
different in different countries.
• Pregnancy and breastfeeding:
• Following pregnancy, the deferral period should last as many months as the duration of the pregnancy.
• It is not advisable to donate blood while breast-feeding. Following childbirth, the deferral period is at least 9
months (as for pregnancy) and until 3 months after your baby is significantly weaned (i.e. getting most of
his/her nutrition from solids or bottle feeding).
•

11. Collection
• The blood is collected aseptically from the median cubital vein, in front of the
elbow.
• Blood is collected in sterile plastic bags or medicinal research council blood bottles
containing an anticoagulant solution.
• During collection the bottle is gently shaken to mix blood and anticoagulant
solution.
• This collected blood is known as whole blood transfusion.
• One unit of donated blood may be divided into components as red cell
concentration, fresh frozen plasma, platelet concentrates etc.

15. Collecting blood step
1.Identify donor and label blood collection bag and test tubes. Ask
the donor to state their full name.
2.Select the vein.
3.Disinfect the skin.
4.Perform the venepuncture.
5.Monitor the donor and the donated unit.
6.Remove the needle and collect samples.

17. Storage
• Blood is withdraw not more than 420 ml at once.
• The blood is transferred to plastic containers, sealed and cooled to 4 to 6 ° C
refrigerators are commonly used for storage of blood components.
• The temperature in all area of refrigerators must be maintained at between 2-6° C.
• The interior of refrigerator must be clean, insulated and there must be well
organization of storage area which are properly labeled and designated for cross
matched blood, labelled blood and outdated blood.
• All blood storage refrigerators must contain recording thermometers and audible
alarms.
• Temperature records are maintained for at atleast 5 years as a part of blood bank
records.

18. • A freezer that can achieve a storge temperature of -20 ° C or lower is required for
storing fresh frozen that plasma and cryoprecipitate.
• The whole blood or its components may be procured by the primary health centre or
any hospital from the government blood banks, Indian red cross society blood banks
or regional blood transfusion centres.